Abstract
The Empirical school of medicine, which arose in the third century BCE, defined itself in opposition to rationalist tendencies in medical thought. Causal explanation, which typically appeals to hidden, theoretical entities, is most at home in rationalist physiology and pathology, and much of what the Empiricists had to say about causes belongs to their anti-rationalist polemics. Over the course of the school’s history, however, some members appropriated the language and idea of cause, though always in ways that was consistent with its defining commitment to Empiricism.