Mothers’ perceptions of their child’s enrollment in a randomized clinical trial: Poor understanding, vulnerability and contradictory feelings

BMC Medical Ethics 14 (1):52 (2013)
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Abstract

Little is known about the views of mothers when their children are invited to participate in randomized clinical trials (RCTs) investigating medicines and/or invasive procedures. Our goal was to understand mothers’ perceptions of the processes of informed consent and randomization in a RCT that divided uncooperative children into three intervention groups (physical restraint, sedation, and general anesthesia) for dental rehabilitation

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