Abstract
The Man is a relational being influenced by the environment and by others. A relationship that can be positive since it allows dialogue, fraternity, affection and care or negative, because it can generate overprotection, destruction and even violence. In this sense, in this work we will delve into the understanding of precisely what is different. For this, we will focus on the case of rare diseases and the mechanisms to minimize the exclusion processes suffered by this group of people, the relationship with medical professionals and aspects related to the world of work, among others. A series of aspects that, due to the low prevalence of these diseases, are little studied so that progress in the knowledge of these diseases is greatly reduced. All this entails serious consequences for the people affected, finding themselves unprotected in areas such as social and labor.