Abstract
Sensory substitution refers to the use of one sensory modality to supply environmental information normally gathered by another sense while still preserving some of the key functions of the original sense. For example, the use of auditory signals might give information about visual scenes. The development of sensory substitution devices has profoundly changed the classical definition of sensory modalities and contributed to the emergence of a form of "artificial synaesthesia". In the last decade, our knowledge about cognitive and brain mechanisms involved in sensory substitution has grown considerably bringing new insights into human perception and neural plasticity. Thanks to technological advances and scientific achievements, sensory substitution has become a real alternative for restoring some functions of a defective sensory organ. This paper addresses some of the major questions raised by sensory substitution, demonstrates how the study of sensory substitution enhances our understanding of human perception and brain plasticity and provides an overview of rehabilitation potentialities.