Abstract

Physicians are trained to an expert degree in the scientific knowledge and skills of biomedicine. Despite this training, however, physicians’ professional lives are rife with instances in which they do not know. They must operate adeptly in the face of numerous uncertainties, as the extensiveness of the scientific literature, unknown mechanisms of pharmaceuticals or biological processes, and variations in patients’ etiologies and anatomies render it impossible to know everything. Similarly, physicians study vast swaths of scientific concepts and clinical skills throughout their careers, yet individual physicians cannot commit all that biomedical knowledge to memory. Given the impossibility of absolute knowledge...