Abstract

The article presents a retrospective analysis of the author’s 70-year contribution to philosophy and science, focusing primarily on the hard problem of consciousness – the relationship between mental phenomena and neurophysiological processes. The author traces his intellectual journey in addressing this fundamental challenge to natural scientific knowledge and presents his conceptual framework, initially developed in the early 1960s. The discussion examines the significant challenges faced in defending an information-based approach to consciousness, particularly during the notable debate with E.V. Ilyenkov and subsequent opposition from his followers who held considerable influence in philosophical circles. Despite ideological pressure and accusations of revisionism, the author successfully advanced his theoretical framework, publishing numerous books and articles that elaborate on his theoretical and methodological approaches to decoding neural correlates of subjective reality. Following the publication of an English-language article outlining his theoretical foundations in a leading international neuroscience journal in 2019, the author received extensive recognition, including invitations to keynote international conferences and join editorial boards of international journals. This response demonstrates the pressing need for theoretical and methodological developments in neuroscience and related disciplines, highlighting a deficit in fundamental theoretical frameworks capable of guiding and integrating empirical research. The article concludes by emphasizing the significance of the information paradigm and its derivative approaches for studying consciousness, mental processes, and genetic aspects of biological functions.