Abstract
Trying to understand better the role played by epistemic artifacts in our quest for reliable knowledge, it is interesting to compare their contribution with the one made by the epistemic organs or systems with which we are naturally endowed. This comparative approach may yield the further benefit of an improved understanding of the nature and epistemic functions of our natural epistemic equipment. In this paper, I shall concern myself with comparing the role of a family of instruments, microscopes, with that of visual systems and with assessing the similarities and dissimilarities in accounts of their epistemic contributions