Reduced self-awareness is a well-known phenomenon investigated in patients with vascular disease; however, its impact on neuropsychological functions remains to be clarified. Importantly, selective vascular lesions provide an opportunity to investigate the key neuropsychological features of reduced self-awareness in neurocognitive disorders. Because of its rarity, we present an unusual case of a woman affected by a combined polar and paramedian bilateral thalamic infarction. The patient underwent an extensive neuropsychological evaluation to assess cognitive, behavioral, and functional domains, with a focus on (...) executive functions. She was assessed clinically in the acute phase and after 6 months from the stroke, both clinically and by magnetic resonance imaging. The patient developed a cognitive impairment, characterised by prevalent executive dysfunction associated with reduced self-awareness and mood changes, in terms of apathy and depression. Such condition persisted after 6 months. In May 2020, the patient underwent the serology test in chemiluminescence to detect IgG antibodies against SARS-CoV-2. The result of the quantitative test highlighted a high probability of previous contact with the virus. We suggest that reduced self-awareness related to executive dysfunction and behavioral changes may be due to combined polar and paramedian bilateral thalamic lesion. Metacognitive–executive dysfunction affecting the instrumental abilities of everyday life might make people less able to take appropriate precautions, facilitating the risk of SARS-CoV-2 contagion. (shrink)

Resumen En este artículo se reflexiona sobre la relación entre literatura y enfermedad, concentrando la atención en la perspectiva de Kierkegaard y de Kafka. Después de analizar la postura kierkegaardiana se pasa a la kafkiana y, finalmente, se comparan los resultados obtenidos. De este modo, se pueden apreciar las diferencias entre los dos planteamientos y, sucesivamente, utilizar los elementos en común para esbozar unas características interesantes sobre la relación entre literatura y enfermedad en los siglos XIX y XX en el (...) contexto de influencia alemana. Esto nos lleva a reflexionar sobre las conexiones causales entre la enfermedad y la literatura, y sobre el contexto social o íntimo en el cual estas se desarrollan.I analyze the topic of sickness in relation to 19th and 20th Century Literature in the Germanophile area. In particular, I examine Kierkegaard's and Kafka's perspectives. In the case of Kierkegaard, he principally wrote about sickness in his diaries, and in two important books: The Concept of Anxiety and The Sickness unto Death. However, Kafka wrote about the same theme in all his diaries. Therefore, in this study, I will compare the different perspectives of these two authors in relation to both sickness and literature. Through this, I will attempt to extract any key aspects that can be used for identifying a more general relation between sickness and literature in the 19th and 20th Centuries. To achieve this aim, I will firstly scrutinize Kierkegaard's posture, and then Kafka's posture. Following this, I will compare the findings to draw general conclusions. (shrink)

Frailty is an age-related dynamic status, characterised by a reduced resistance to stressors due to the cumulative decline of multiple physiological systems. Several researches have highlighted a relationship between physical frailty and cognitive decline; however, the role of specific cognitive domains has not been deeply clarified yet. Current studies have hypothesised that physical frailty and neuropsychological deficits may share systemic inflammation and increased oxidative stress in different neurodegenerative disorders, such as Alzheimer’s and Parkinson’s disease. However, the role of the executive (...) dysfunction should be investigated in a more detailed way using a multidimensional approach. With this aim, we conducted a review of the literature on the few experimental articles published to discuss the existence of a relationship between frailty and cognitive impairment in neurocognitive disorders, particularly focusing on the domain of executive dysfunction. The data suggest that physical frailty and cognitive decline, especially executive dysfunction, are two aspects strongly linked in mild and major neurocognitive disorders due to Alzheimer's and Parkinson's disease. In light of this, a new framework linking ageing, cognitive decline, and neurodegenerative diseases is needed. In order to analyse the effects that ageing processes have on neural decline and neurocognitive disease, and to identify relevant groups of users and patients, future longitudinal studies should adopt a multidimensional approach, in the field of primary prevention and in the continuum from mild to major neurocognitive disorder. (shrink)

Tu duca, tu signore, e tu maestro». Con estas palabras se inicia una relación educativa entre Virgilio y Dante que manifiesta de manera concreta una visión sobre el maestro de permanente validez y actualidad. El viaje de Dante permite descubrir en la Divina Comedia la existencia de unos principios universales que fundamentan la acción del maestro. No obstante, dichos principios no son del todo originales, sino que permiten evidenciar la influencia que Tomás de Aquino ha ejercido en Dante. El Aquinate (...) no solo es mencionado en el Paraíso en los cantos X al XIV, sino que los principios pedagógicos tomistas, especialmente los contenidos en la Suma de Teología, informan la relación concreta entre los dos poetas. En este estudio intentaremos explicitar la visión del maestro propuesta por Dante, a la vez que se buscará mostrar que Tomás de Aquino es la fuente principal de la que Dante se nutre para labrar esa específica relación entre maestro y discípulo. (shrink)

El texto pretende analizar la relación entre la condición de ceguera que puede afectar a un sujeto y sus implicaciones en la actividad poiética del mismo. Para ello, acudimos a la reflexión heideggeriana sobre la poiesis como raíz común de los actuales conceptos de técnica y arte, ilustrando cómo la situación de ceguera puede ser favorable (o no) para las prácticas poiéticas. El análisis se desarrollará considerando, inicialmente, uno de los primeros ejemplos literarios de la Modernidad en plantear la relación (...) entre la ceguera y la poiesis: la última escena del Fausto de Goethe, en donde el protagonista, luego de haber quedado ciego, decide construir un dique para contener la fuerza del mar. En una segunda parte, se complementarán nuestras observaciones con el estudio de algunos casos clínicos que Oliver Sacks expone en sus obras para destacar otras facetas de la relación entre ceguera y poiesis en un contexto de no ficción literaria. Con este análisis, se explicita de una manera clara que existe una relación entre poiesis y ceguera en el Fausto de Goethe y se identifican los rasgos de dicha correlación, destacando también su relevancia en el ámbito terapéutico y existencial de los estudios sobre ceguera. (shrink)

Awareness of deficits in patients with neurological disorders may be described as a theoretical unitary phenomenon, which has been analysed reaching interesting results in the last decades. Awareness of deficits manifests itself in a continuum ranging from full awareness to total absence. In line with a neurocognitive approach, a reduction in self-awareness could be explained considering executive dysfunction associated with prefrontal cortex anatomo-functional changes. Our mini-review will focus on reduced self-awareness in neurological disorders, such as Alzheimer’s disease, behavioural Frontotemporal Dementia (...) and Acquired Brain Injuries. Results achieved thanks to an explanatory investigative approach combined with a theoretical reference model will be presented. Data suggest the key role of executive functions in supporting adequate self-awareness towards patients’ cognitive-behavioural profile and instrumental activity autonomy. The Cognitive Awareness Model seems to be one of the best theoretical model to better approach this phenomenon. (shrink)

The COVID-19 pandemic is a health issue leading older adults to an increased vulnerability to unfavorable outcomes. Indeed, the presence of physical frailty has recently led to higher mortality due to SARS-CoV-2 infection. However, no longitudinal studies have investigated the role of neuropsychogeriatric factors associated with lockdown fatigue in healthy cognitive aging. Eighty-one healthy older adults were evaluated for their neuropsychological characteristics, including physical frailty, before the pandemic. Subsequently, 50 of them agreed to be interviewed and neuropsychologically re-assessed during the (...) lockdown and immediately after it. Moreover, during another home confinement, they performed a psychological screening to evaluate possible mood changes and fatigue. According to Fried's frailty criteria, at T0, 63% of the sample was robust, 34.5% pre-frail, and only 2.5% frail. Significantly, these subjects presented a decrease in handgrip strength and walking speed. Results from Principal Component Analyses and multiple regression models highlighted the contribution of “cognitive” and “psychological” factors in explaining handgrip strength and gait speed. At T3, lockdown fatigue was explained by higher scores on the Beck Depression Inventory and lower scores on the Trail Making Test part A. Results from a moderated-mediation model showed that the effect of psychomotor speed on lockdown fatigue was mediated by depression, with a moderating effect of gait speed. Our findings highlight the complex interrelationship between cognitive, psychological, and physical factors in the emergence of pandemic fatigue in a carefully selected older population. (shrink)

There is ample evidence from literature and clinical practice indicating mathematical difficulties in individuals with ADHD, even when there is no concomitant diagnosis of developmental dyscalculia. What factors underlie these difficulties is still an open question. Research on dyscalculia and neurotypical development suggests visual perception of numerosity (the number sense) as a building block for math learning. Participants with lower numerosity estimation thresholds (higher precision) are often those with higher math capabilities. Strangely, the role of numerosity perception in math skills (...) in ADHD has been neglected, leaving open the question whether math difficulties in ADHD also originate from a deficitary visual number sense. In the current study we psychophysically measured numerosity thresholds and accuracy in a sample of children/adolescents with ADHD, but not concomitant dyscalculia (N = 20, 8–16 years). Math abilities were also measured by tasks indexing different mathematical competences. Numerosity performance and math scores were then compared to those obtained from an age-matched control group (N = 20). Bayesian statistics indicated no difference between ADHD and controls on numerosity perception, despite many of the symbolic math tasks being impaired in participants with ADHD. Moreover, the math deficits showed by the group with ADHD remained substantial even when numerosity thresholds were statistically regressed out. Overall, these results indicate that math difficulties in ADHD are unlikely to originate from an impaired visual number sense. (shrink)

El artículo analiza la interpretación que Adorno hace de Kafka en Apuntes sobre Kafka, concentrando la atención en la consideración sobre Kafka como un escritor ilustrado que critica la Ilustración, con el fin de determinar si dicha afirmación es o no coherente con la teoría adorniana. Para esto, se compara la lectura que Adorno y Kafka hacen del episodio del canto de las sirenas de la Odisea y se analizan las diferencias existentes entre las dos interpretaciones. Gracias a ello podemos (...) concluir, parcialmente en contra de Adorno, que Kafka es un crítico de la Ilustración, aunque no es un escritor ilustrado. (shrink)

Este artículo analiza las estrategias de enmascaramiento que Kierkegaard y Kafka adoptaron a lo largo de sus vidas. En primer lugar, se analizan algunos rasgos de la sociedad burguesa y del papel que el escritor tenía en ella. Sucesivamente, se describe la estrategia comunicativa de Kierkegaard y se identifican sus fines; después se hace la misma operación respecto de Kafka. Finalmente, se comparan las dos posturas y se subrayan diferencias y similitudes, para utilizar los resultados como insumos para una breve (...) reflexión sobre el papel de la escritura en la moderna sociedad burguesa. (shrink)

Among the accusations raised against Peter of John Olivi, during the Council of Vienne, one of the strongest concerned de ecclesia vocata Magna meretrix. The Council Fathers were concerned about the identification of the great prostitute of the Apocalypse with the Roman See. This interpretation, as we know, was well weighed by Ubertino de Casale, and the pope, Clement the fifth, preferred to leave the question aside and it disappeared in the final texts of the Council.1The recent “double” publication of (...) the Lectura super Apocalipsim2 now permits us reconsider the question of the conciliar fathers of Vienne regarding the identification between the Church and the great prostitute of Apocalypse. In addition, we can... (shrink)

This book aims to spur critical thought on the various dimensions and impacts of "responsibility" for organizations, including companies, institutions, and governments, while considering international differences and similarities, as well as global challenges. It analyzes to what extent responsibility is becoming a crucial issue for all kinds of organizations, examining both the intensifying pressures of international competition and the growing crisis of confidence towards some management concepts and practices. As more and more socio-economic and political systems are suspected of serving (...) selfish interests instead of the public good, more accountable and integrated processes are appropriate in order to deal with the present and future stakes of our society. Further, with the development of digital technology and the use of data mining, new questions regarding responsibility require examination. This edited collection is a culmination of the international scientific conference "Responsible Organizations in the Global Context", co-organized by the CIED of Georgetown University (United States) and the Larequoi Research Center of the University of Versailles St-Quentin (France) in June 2017 in Washington DC. It will contribute to research and actions in the areas of social responsibility, business ethics, organizational excellence, sustainability, and cross-cultural management. (shrink)

Several mechanisms of perceptual and cognitive relevance which are often activated during artistic fruition are illustrated. These are phenomena of ambiguity, incongruity and masking, largely clarified in their dynamics by perception and thinking psychology researchers. The connections between these phenomena and the psychoanalytic concepts of ambivalence, conflict and repression are indicated. It is claimed that appropriate consideration of these psychological references contributes to enrich complex communications comprehension, such as in the case of artistic languages. Through analyses carried out on renaissance (...) and contemporary works of art, it is shown how the use of the meanings suggested by the above mentioned perceptual phenomena allows to highlight latent contents. (shrink)