Background: Only data of published study results are available to the scientific community for further use such as informing future research and synthesis of available evidence. If study results are reported selectively, reporting bias and distortion of summarised estimates of effect or harm of treatments can occur. The publication and citation of results of clinical research conducted in Germany was studied.Methods: The protocols of clinical research projects submitted to the research ethics committee of the University of Freiburg in 2000 were (...) analysed. Published full articles in several databases were searched and investigators contacted. Data on study and publication characteristics were extracted from protocols and corresponding publications.Results: 299 study protocols were included. The most frequent study design was randomised controlled trial , followed by uncontrolled studies , laboratory studies and non-randomised studies . 182 were multicentre studies including 97 international collaborations. 152 of 299 had commercial funding and 46 non-commercial funding. 109 of the 225 completed protocols corresponded to at least one full publication ; the publication rate was 48%. 168 of 210 identified publications were cited in articles indexed in the ISI Web of Science. The median was 11 citations per publication .Conclusions: Results of German clinical research projects conducted are largely underreported. Barriers to successful publication need to be identified and appropriate measures taken. Close monitoring of projects until publication and adequate support provided to investigators may help remedy the prevailing underreporting of research. (shrink)

Encyclopedic dictionary of Yogasūtra of Patañjali.

I would like to begin with the role of philosophy in solving ecological problems, emphasizing two aspects of its role: the struggle against hostile ideology and the organizing and guiding of activity in the sphere of the development of science and the shaping of its problems. This role of Marxist-Leninist philosophy clearly appears in the complex interdisciplinary problem of the interaction between nature and society.

Brain tumor classification plays a niche role in medical prognosis and effective treatment process. We have proposed a combined feature and image-based classifier for brain tumor image classification in this study. Carious deep neural network and deep convolutional neural networks -based architectures are proposed for image classification, namely, actual image feature-based classifier, segmented image feature-based classifier, actual and segmented image feature-based classifier, actual image-based classifier, segmented image-based classifier, actual and segmented image-based classifier, and finally, CFIC. The Kaggle Brain Tumor Detection (...) 2020 dataset has been used to train and test the proposed classifiers. Among the various classifiers proposed, the CFIC performs better than all other proposed methods. The proposed CFIC method gives significantly better results in terms of sensitivity, specificity, and accuracy with 98.86, 97.14, and 98.97%, respectively, compared with the existing classification methods. (shrink)

Книга представляет собой собрание избранных докладов, прочитанных на семинаре в 2004-2009 гг.

Монография посвящена теории и практике очеловечивания человека. Уделено внимание факторам, способствующим укреплению здоровья и восхождению человека к своей истинной природе, или, наоборот, способствующим его деградации.

В книге говорится о творце, генерирующем творческие акты – непредсказуемые решения and (озарения and ), феномены, которыми обладает только человек-личность. Общественные институты, как и само общество в целом, не могут исключительно своими социальными усилиями генерировать творческий акт. Таким образом, без этого личностного, практически абсолютно автономного, творческого решения общество не может ни обойтись, ни чем-либо его заменить. Используя творческие акты, эти феномены, имманентные только человеку, общество консолидируется и развивается, и, таким образом, человек-творец становится двигателем истории человечества. В этом смысле категория личность (...) имеет не меньшую значимость, чем категория производительные силы или категория общество. Рассматривается концепция природы творчества по Вифляеву, с полным философским обоснованием. (shrink)