The posterior parietal cortex (PPC) is the most likely site where egocentric spatial relationships are represented in the brain. PPC cells receive visual, auditory, somaesthetic, and vestibular sensory inputs; oculomotor, head, limb, and body motor signals; and strong motivational projections from the limbic system. Their discharge increases not only when an animal moves towards a sensory target, but also when it directs its attention to it. PPC lesions have the opposite effect: sensory inattention and neglect. The PPC does not seem (...) to contain a “map” of the location of objects in space but a distributed neural network for transforming one set of sensory vectors into other sensory reference frames or into various motor coordinate systems. Which set of transformation rules is used probably depends on attention, which selectively enhances the synapses needed for making a particular sensory comparison or aiming a particular movement. (shrink)

The paper begins with consideration of Plato and Aristotle, but the question addressed in this essay is the following: What has been meant--and what role has been played--in the succession of doctrines of physics we have had since the seventeenth century, by notions of “power” and of “cause”? The essay concludes with consideration of field theories set in relativistic space-time.

Enzymes are protein catalysts of extraordinary efficiency, capable of bringing about rate enhancements of their biochemical reactions that can approach factors of 1020. Theories of enzyme catalysis, which seek to explain the means by which enzymes effect catalytic transformation of the substrate molecules on which they work, have evolved over the past century from the “lock-and-key” model proposed by Emil Fischer in 1894 to models that explicitly rely on transition state theory to the most recent theories that strive to provide (...) accounts that stress the essential role of protein dynamics. In this paper, I attempt to construct a metaphysical framework within which these new models of enzyme catalysis can be developed. This framework is constructed from key doctrines of process thought, which gives ontologic priority to becoming over being, as well as tenets of a process philosophy of chemistry, which stresses environmentally responsive molecular transformation. Enzyme catalysis can now be seen not as enzyme acting on its substrate, but rather as enzyme and substrate entering into a relation which allows them to traverse the reaction coordinate as an ontologic unity. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:preface This issue of Feminist Studies includes a cluster of essays that demonstrates new approaches to life writing, with special attention to unconventional women’s autobiographies. Lara Vapnek describes the historical inhibitions that shaped the self-presentation of pioneering American labor activist Elizabeth Gurley Flynn in the early twentieth century such that she omitted her sexual relationships with both women and men from her autobiographical writings. Overlapping with Vapnek’s historical focus, (...) Nora Doyle’s essay takes a new look at Gertrude Stein’s bestknown and most accessible work, The Autobiography of Alice B. Toklas, seeing it as Stein’s clever reworking of the women’s genre of domestic fiction in its pairing of a domesticated wife with a “genius” husband. In her examination of Kamala Das’s Balyakala Smaranakal (Memories of childhood), Sharmila Sreekumar discusses how the memoir’s depiction of self-deferral rather than self-realization unsettles autobiographical conventions through its troubling of the relationship between “self,” “life,” and “writing” that is constitutive of the genre. In Olga Zilberbourg’s short story, two women are baffled as they contemplate a friend’s suicide: what does it say about their own accomplishments and losses? Attention to the visual aspects of women’s lives and to their embodiment is highlighted in Estelle Carol’s memoir about her time spent as a member of the Graphic Collective of the Chicago Women’s Liberation Union in the 1970s. Corey Hickner-Johnson’s lyrical essay describes the first-person I of the poem as pushing herself to a physical extreme. Her autobiographical crisis-moment, depicted in acutely visceral and visual terms, wills into relief life’s underlying colors against a backdrop of otherwise drab monotony and disappointment. Feminist graphic artwork is discussed in Hillary Chute’s review essay on the newly popular genre of graphic novels by women. Alexandra Ketchum’s “‘The Place We’ve Always Wanted to Go But Never Could Find’: Finding Woman Space in Feminist Restaurants and Cafés in Ontario 1974–1982” and Samantha Pergadia’s “Geologies of 8 Sex and Gender: Excavating the Materialism of Gayle Rubin and Judith Butler” shift our attention away from individual life trajectories to broader sweeps of space and time. Ketchum’s history of feminist restaurants and cafes in Ontario, Canada, in the mid 1970s to early 1980s encourages us to consider the importance of space to the formation of feminist solidarities and political organizing, while Pergadia’s analysis of the geological understandings that undergird the work of both Gayle Rubin and Judith Butler invites us to rethink the temporalities through which gendered and sexed subjects, as well as academic disciplines, are formed. In closing, Ashwini Tambe reflects on the #MeToo movement and how we might fashion a more responsive public reckoning with sexual coercion. The issue leads off with Vapnek’s essay, “The Rebel Girl Revisited: Rereading Elizabeth Gurley Flynn’s Life Story.” As Vapnek details, Flynn, an activist in the Industrial Workers of the World, chronicled her life only as far as 1926. Although she envisioned women’s emancipation as an integral component of the socialist revolution, her self-censorship reveals “how communism as well as anticommunism has limited our knowledge of the feminist past.” Flynn remained committed to socialism and women’s rights and continued to agitate for social change, but her efforts to narrate her later life were stymied by internal inhibitions and external forces. For a decade she lived with another woman at a time when leftists were not open about same-sex relationships. Nor did she wish to reveal her sexual relationships with a number of men or the psychological breakdown she suffered in 1926. Joining the US Communist Party in 1936 re-energized her career as a labor organizer and resulted in her being sent to prison from 1955 to 1957 during the period of the Red Scare in the United States. By her middle age, she had experienced not only nonconventional personal relationships but also a dramatic change in her appearance: rather than the slim girl pictured on the cover of songs designed to encourage the labor movement, she was a stout, matronly woman. Inhibited from revising her autobiography to account for her later life... (shrink)

This is a paperback edition of what has become an important contribution to aesthetics and the theory of literature. The author analyses in detail how the reader responds to literature and how he begins to evaluate it. Mr Olsen characterizes literature as an institution and thus forges links with contemporary philosophy which sees all human action as ordered and defined by social institutions.

Many people believe that a person's sexual orientation is genetic. Given the widespread prejudice against, and hatred of, homosexuals in many societies, it seems likely that many parents will be interested in using genetic technologies to prevent the birth of children who will not be heterosexual. This paper considers the moral and legal implications of such procedures (whether or not they would work). It is argued that the availability of procedures to select the sexual orientation of children would contribute to (...) discrimination and prejudice against lesbians, gay men and bisexuals and, more generally, undermine the maintenance of a just society. These effects carry significant weight in determining whether genetic technologies should be developed and whether their use is, or should be, legally permissible and morally acceptable. (shrink)

A Special Issue of the Journal of Philosophy of Education, 2005, issue 2, contains an interesting ‘Philosophy of the Teacher’ by Nigel Tubbs. It rejects attempts in pedagogical traditions to ignore or avoid the contradiction between the teacher as master and as servant, and ends with an interpretation of ‘upbuilding’, a central concept in Søren Kierkegaard’s writings. According to Tubbs’ reading, the teacher’s patient struggle with herself in doubt is the basic condition for upbuilding, whereby the eternal’s perfect gift of (...) love is given to the students. I maintain that the original Danish text does not fully support this interpretation and defend an alternative reading. The text says that the condition for receiving the perfect gift is itself a gift of God. Doubt is necessary, but if our doubt were sufficient, we could manage our lives without God, the condition for receiving the gift would not be a gift, and the possibility for receiving the gift would be spoiled both for teachers and students. (shrink)

Grafts of embryonic neural tissue into the brains of adult patients are currently being used to treat Parkinson's disease and are under serious consideration as therapy for a variety of other degenerative and traumatic disorders. This target article evaluates the use of transplants to promote recovery from brain injury and highlights the kinds of questions and problems that must be addressed before this form of therapy is routinely applied. It has been argued that neural transplantation can promote functional recovery through (...) the replacement of damaged nerve cells, the reestablishment of specific nerve pathways lost as a result of injury, the release of specific neurotransmitters, or the production of factors that promote neuronal growth. The latter two mechanisms, which need not rely on anatomical connections to the host brain, are open to examination for nonsurgical, less intrusive therapeutic use. Certain subjective judgments used to select patients who will receive grafts and in assessment of the outcome of graft therapy make it difficult to evaluate the procedure. In addition, little long-term assessment of transplant efficacy and effect has been done in nonhuman primates. Carefully controlled human studies, with multiple testing paradigms, are also needed to establish the efficacy of transplant therapy. (shrink)

We have reason to think that a fundamental goal of natural science, on Aristotle’s view, is to discover the essence-specifying definitions of natural kinds—with biological species as perhaps the most obvious case. However, we have in the end precious little evidence regarding what an Aristotelian definition of the form of a natural kind would look like, and so Aristotle’s view remains especially obscure precisely where it seems to be most applicable. I argue that if we can get a better understanding (...) of how the forms of natural kinds are or come to be known, and how they make things intelligible, we can get a better appreciation of the nature of form in general, as well as solve certain puzzles about form and definition. (shrink)

Cohen (1981) and others have made an interesting argument for the thesis that humans are rational: normative principles of reasoning and actual human reasoning ability cannot diverge because both are determined by the same process involving our intuitions about what constitutes good reasoning as a starting point. Perhaps the most sophisticated version of this argument sees reflective equilibrium as the process that determines both what the norms of reasoning are and what actual cognitive competence is. In this essay, I will (...) evaluate both the general argument that humans are rational and the reflective equilibrium argument for the same thesis. While I find both accounts initially appealing, I will argue that neither successfully establishes that humans are rational. (shrink)

For more than a century, law schools have trained students to 'think like a lawyer'. In these times of legal crisis, both in legal education and in global society, what does that mean for the rest of us? In this book, thirty leading international scholars - including Louis Assier-Andrieu, Marianne Constable, Yves Dezalay, Denise Ferreira da Silva, Bryant G. Garth, Peter Goodrich, Duncan Kennedy, Martti Koskenniemi, Shaun McVeigh, Samuel Moyn, Annelise Riles, Charles F. Sabel and William H. Simon - examine (...) what is distinctive about legal thought. They probe the relation between law and time, law and culture, and legal thought and legal action; the nature of current legal thought; the geography of legal thought; and the conditions for recognition of a new 'contemporary' style of law. This work will help theorists, social scientists, historians and students understand the intellectual context of legal problems, legal doctrine, and jurisprudential trends in the current conjuncture. (shrink)

Philosophers discussing causation take on, as one of their responsibilities, the task of specifying an ontology of causation. Both standard and non-standard accounts of that ontology make two assumptions: that the ontological category of causal relata admits a unique specification, and that cause and effect are of the same ontological type. These assumptions are rarely made explicit, but there is in fact little reason to think them true. It is argued here that, if the question has any interest, there are (...) some considerations in favor of rejecting Uniqueness and Uniformity, no good reasons in favor of them, but good reason to think that we are not in a position to make a decisive pronouncement, since some of the information needed to make a judgement on the matter is empirical in character. Philosophers have therefore made two mistakes about the relata of causation: one is to have accepted unwarranted restrictions on the categories pertinent to causation; the other is to have wrongly assumed that we are in a position to name them. (shrink)

Residências Integradas Multiprofissionais em Saúde são programas de pós-graduação caracterizados por ensino em serviço. A ULBRA oferece o programa com ênfase em Saúde do Adulto e do Idoso e Saúde Comunitária. Objetiva-se descrever as atividades realizadas em ambiente hospitalar por enfermeiras. Trata-se de um relato de experiência de enfermeiras residentes em relação ao primeiro ano de formação especializada. O primeiro ano de residência abrangeu atividades em unidades de internação, centro cirúrgico e unidade de tratamento intensivo. Diversas foram as atividades desenvolvidas (...) pelas residentes, abrangendo aperfeiçoamento técnico, produção de conhecimento científico e atuação em gestão e gerenciamento. A presença de tutores e preceptores é fundamental no sentido de discutir, orientar e facilitar a inserção e o desenvolvimento profissional do residente. O programa de residência permitiu aperfeiçoar habilidades nos três campos de atuação da categoria: assistência, gerenciamento e pesquisa. (shrink)

The alleged but unclear distinction between so-called “immanent” and so-called “transeunt” causation is structurally similar to an Aristotelian distinction between two kinds of potentiality (dunamis). It is argued that Aristotle’s distinction is in turn grounded in one between a metaphysically basic notion, rooted in his property theory, and a metaphysically posterior notion proper to the understanding of change in the science of nature. By examining Aristotle’s distinction, we can give a satisfying account of immanent and transeunt causation more generally. Furthermore, (...) once we clarify the distinction in this way, some contemporary appeals to immanent causation turn out to be misguided, while others look promising. (shrink)

This chapter contains sections titled: Philosophical Context Knowing History The Content of History and Historiography Conclusion Further Reading.

Evans distinguishes between superficial necessity and deep necessity in his analysis of the contingent a priori. The distinction between these two notions of necessity is formalized by Davies and Humberstone through the addition of the operator Fixedly to Actuality Modal Logic (AML, S5A), where deep necessity is represented by the combination Fixedly Actually. Wehmeier’s Subjunctive Modal Logic (SML) provides an extension of the expressive capacity of ordinary modal predicate logic alternative to AML. I add Fixedly to SML and show that (...) in the system SML with Fixedly the distinction between deep and superficial necessity disappears. I conclude that the existence of the distinction between deep and superficial necessity, as well as the existence of the contingent a priori, cannot be asserted independently of the choice of background logic. (shrink)

Dans la Russie post-soviétique, on dénombre environ 12 millions de personnes qui vivent en situation de handicap. Cependant, les recherches scientifiques consacrées à ce large segment de la société russe, principalement à propos de la stigmatisation et de l’auto-stigmatisation, sont rares. Les textes autobiographiques écrits par des personnes qui présentent un handicap, entre 1990 et 2010, permettent de mieux comprendre les expériences de ces personnes dans la Russie post-soviétique. Ces textes témoignent notamment des principales stratégies que les personnes qui présentent (...) des incapacités motrices congénitales ou acquises ont adopté afin de s’adapter aux défis de la vie quotidienne. Le diagnostic médical a profondément transformé le statut social et le mode de vie de ces personnes. Cet article examine le diagnostic selon la perspective des théories du “rite de passage” vers un autre monde, le monde des personnes handicapées, leur “bas-monde.” En s’appuyant sur les autobiographies de personnes handicapées, cet article révèle comment les étiquettes et les notions appliquées à l’infirmité au sein de la société russe contemporaine sont enracinées dans la culture russe dans son ensemble et dans les attitudes soviétiques envers le handicap et les personnes handicapées. (shrink)

In this book Robert Stecker sets out to answer three basic questions in the philosophy of art: What is art? What is it to understand a work of art? And what is the value of art? Stecker addresses each question in turn and delivers what he claims to be “a unified, if incomplete, philosophy of art—a theory of the nature and functions of art and of the practice of interpreting and appreciating it”. His strategy is to discuss thoroughly recent contributions (...) to the debate concerning each of these questions and to put forward his own alternative answers. This leads to an extensive and detailed discussion of the journal literature on each of these subjects and considerable effort is spent both presenting and evaluating this literature. (shrink)

The articles in this collection focus attention on the concept of literature and on the relationship between this concept and the concepts of a literary work and a literary text. Adopting an analytic approach, the articles attempt to clarify how these concepts govern our thinking about the phenomenon of literature in various ways, exploring the issues which arise when these concepts are employed as theoretical instruments for describing and analyzing the phenomenon of literature.

In the course of the nineteenth century the study of literature was professionalized. There was a concerted attempt to make the study of literature an academic pursuit, ‘a particular branch of learning or science’, to turn it into ‘literary studies’ or, as it was called in German, Literaturwissenschaft. 1 This attempt was ultimately successful in the sense that literary studies became a recognized and established discipline within the new Humboldtian kind of university. However, this success brought troubles of its own. (...) Among other things, the arrival of the academic discipline of literary studies not only required a method of study but also a determinate field of study. In order to delimit such a field, a clear and well-defined concept of literature was needed. This meant that academic literary studies would have to transform, for its own specific purposes, such concepts as ‘literary work’ and ‘literary text’ as well as the concept of ‘literature’, from broad, vague, non-theoretical, everyday notions into something like well-designed theoretical tools. Though it has not always been recognized, this transformation has presented a major theoretical problem for literary studies, and it is arguable that to this day no satisfactory solution has been found. (shrink)

P. D. Juhl, Interpretation. An Essay in the Philosophy of Literary Criticism, Princeton University Press, Princeton, N.J. 1980, 332 pp., no price given. References in parentheses are to this work.

This article explores the relationship between interpretation and what is normally called ‘understanding’. It is argued that different modes of interpretation define different kinds of ‘mental uptake’ (‘apprehension’), and that some modes of interpretation define types of apprehension for which the concept of ‘understanding’ is inadequate. It is also argued that given a mode of interpretation, the constraints of that mode are necessary in the sense that it is the constraints on how to interpret that define a mode of interpretation. (...) Thus within a mode of interpretation (historical, literary) one cannot interpret freely. Indeed, unconstrained interpretation is not interpretation. In order to illustrate these points the article offers a detailed discussion of two examples. The interpretative debate over the Magna Carta is used to illustrate the difference between a constitutional and a historical interpretation. These two modes of interpretation are then contrasted with literary interpretation, the aim of which is appreciation. (shrink)