As biobank research has become increasingly widespread within biomedical research, study-specific consent to each study, a model derived from research involving traditional interventions on human subjects, has for the sake of feasibility gradually given way to alternative consent models which do not require consent for every new study. Besides broad consent these models include tiered, dynamic, and meta-consent. However, critics have pointed out that it is normally not known at the time of enrolment in what ways samples deposited in a (...) biobank may be used in future research and that, for a consent to be informed, exactly this kind of knowledge is required. Therefore, there is an ongoing debate about the ethical acceptability of going for less than study-specific consent. In light of this debate we address the question of how to best protect participants against relevant risks and violations of autonomy. We apply the central aims of the informed consent process to the unique circumstances of biobank research where samples and data in many cases are stored for long periods of time and reused in subsequent studies. Thereby we are able to formulate a set of criteria focusing both on the risk of informational harm and the potential violation of participants’ values. We compare existing models of consent based on their ability to satisfy the criteria, and we find that the broad consent model offers the best level of protection for participants, although, it suffers from a few important deficiencies with regards to protection against participant value violations and long-term protection of autonomy, if it is applied without qualifications. For this reason, we propose modifications to the current broad consent model, in order to ensure that it provides protection of autonomy and participant values through strong ethical review and continuous communication. We conclude that a modified form of broad consent is ethically superior in biobank research, not only because it is most feasible but primarily because it offers the best available protection against the hazards facing research subjects in this form of research. (shrink)

Global climate change is likely to become a major cause of future migration. Small Island States are particularly vulnerable since territorial destruction caused by sea level rise poses a threat to their entire existence. This raises important issues concerning state sovereignty and self-determination. Is it possible for a state to remain self-determining even if it lacks a stable population residing on a specific territory? It has been suggested that migrants from disappearing Small Island States could continue to exercise sovereign control (...) over their abandoned territory. Such an arrangement would allow them to retain a measure of self-determination. The question posed in this paper is whether this ?deterritorialized state proposal? is conceptually plausible and normatively acceptable. It is argued that the proposal is conceptually plausible if we adopt a gradual understanding of ?self-determination?, but that its normative acceptability is weak even if it is supplemented with compensatory measures. (shrink)

Late eighteenth-century writings on race by Kant and four of his contemporaries.

Recently Carrie S. Jenkins formulated an epistemology of mathematics, or rather arithmetic, respecting apriorism, empiricism, and realism. Central is an idea of concept grounding. The adequacy of this idea has been questioned e.g. concerning the grounding of the mathematically central concept of set (or class), and of composite concepts. In this paper we present a view of concept formation in mathematics, based on ideas from Carnap, leading to modifications of Jenkins’s epistemology that may solve some problematic issues with her ideas. (...) But we also present some further problems with her view, concerning the role of proof for mathematical knowledge. (shrink)

We propose an account of interpretive effects involving _same_ and _different_, relying on two claims: the first is that _same_ and _different_ are able to take scope, and the second is that they are presuppositional. On this account, _same_ and _different_ are decomposed into two parts: an additive operator TOO and a (non-)identity predicate. We argue that this account provides a more parsimonious account of well-known properties of _same_ and _different_, such as the distinction between internal and external readings, as (...) well as the parallelism effects discovered by Hardt and Mikkelsen (Linguist Philos 38:289–314, 2015). We also present a solution to a previously unexplained puzzle involving comparatives. (shrink)

St. Thomas’s commentary on the Book of Psalms, known as the Postilla super Psalmos, gives us a privileged insight into the mind and heart of a Dominican friar and theologian at work and at prayer. In this contribution I will elucidate these claims on the basis of elements found in his commentary and in particular in the areas of prayer and the liturgy, Christ, Mary and the Church, Sin and Mercy and Contemplation and Preaching.

The purpose of this dissertation is to establish an interpretive framework for the study of Kant's Critique of Judgment. The central themes of the text are presented in the first chapter in terms of two different problems. The first is referred to as the prima facie problem. This problem concerns the search for a transcendental principle for the faculty of judgment corresponding to the principles established for understanding and reason in the first two critiques. The second is referred to as (...) the systematic problem. This problem concerns the search for a transcendental principle which can mediate between the domains of understanding and reason and provide for a "unity of transition" between nature and freedom. ;The value of this interpretation is demonstrated in the second chapter through a criticism of Paul Guyer's work on the third critique, Kant and the Claims of Taste . This criticism focuses on Guyer's interpretive method and scholarship. ;The interpretation is developed further in the third and fourth chapters in which specific problems that have not been dealt with adequately in the recent literature in English are addressed. The systematic argument of the two introductions that Kant prepared for the text is presented in the third chapter. Finally, the fourth chapter focuses on the deduction of pure aesthetical judgments and advances an account of this argument that is shown to be preferable to the account of Guyer as well as that developed by Donald Crawford in his study Kant's Aesthetic Theory. (shrink)

On the basis of a chronological approach of the decision-making process with regard to the recognition of the PRC we concluded in an analytical part that the decision-making process was merely of the "hypo-institutional" type. Afterwards, we examined the effectivity of the Belgian policy in comparison with the international scientific literature on recognition and with the practice of other small European states. We concluded the non-recognition policy had been ineffective. The relation between "hypo-institutional" decision-making on the one hand and ineffective (...) public policy on the other hand is just one element within a broader research-project : "The effectivity of public policy according to type of decisionmaking". (shrink)

Background Discussions on ethical aspects of life-and-death decisions within the hospital are often made in plenary. The prehospital physician, however, may be faced with ethical dilemmas in life-and-death decisions when time-critical decisions to initiate or refrain from resuscitative efforts need to be taken without the possibility to discuss matters with colleagues. Little is known whether these considerations regarding ethical issues in crucial life-and-death decisions are documented prehospitally. This is a review of the ethical considerations documented in the prehospital medical records (...) of patients in a Danish prehospital setting for whom the decision to resuscitate or not was made at the scene. Methods The study is based on discharge summaries of all patients subjected to crucial life-and-death decisions by the Mobile Emergency Care Unit in Odense in the years 2010 to 2014. The medical records with possible documentation of ethical issues were independently reviewed by two philosophers in order to identify explicit ethical or philosophical considerations pertaining to the decision to resuscitate or not. Results In total, 1275 patients were either declared dead at the scene without exhibiting layman’s reliable signs of death or admitted to hospital following resuscitation. In a total of 62 patients, 85 specific ethical issues related to resuscitation were documented. The expressions of the ethical considerations were generally vague or unclear and almost exclusively concerned the interests of the patient and not the relatives. In the vast majority of cases where an ethical content was identified, the ethical considerations led to a decision to terminate treatment. Conclusions A strengthened practice of documenting ethical considerations in prehospital life-and-death decision-making in the patient’s medical records is required. We suggest that a template be implemented in the prehospital medical records describing the basis for any ethical decisions. This template should contain information regarding the persons involved in the deliberations and notes on ethical considerations. The documentation should include considerations concerning the patient’s end-of-life wishes, the estimations of the quality of life before and after the incident, and a summary of other ethical concerns taken into account, such as the integrity of the patient and frame of mind of relatives. (shrink)

One questioned premiss in the indispensability argument of Quine and Putnam is confirmational holism. In this paper I argue for a weakened form of holism, and thus a strengthened version of the ind ..

Using Carnap’s concept explication, we propose a theory of concept formation in mathematics. This theory is then applied to the problem of how to understand the relation between the concepts formal proof and informal, mathematical proof.

Current debate and policy surrounding the use of genetic editing in humans often relies on a binary distinction between therapy and human enhancement. In this paper, we argue that this dichotomy fails to take into account perhaps the most significant potential uses of CRISPR-Cas9 gene editing in humans. We argue that genetic treatment of sporadic Alzheimer’s disease, breast- and ovarian-cancer causing BRCA1/2 mutations and the introduction of HIV resistance in humans should be considered within a new category of genetic protection (...) treatments. We find that if this category is not introduced, life-altering research might be unnecessarily limited by current or future policy. Otherwise ad hoc decisions might be made, which introduce a risk of unforeseen moral costs, and might overlook or fail to address some important opportunities. (shrink)

Attempts have been made to analyse features in mathematics within a social constructivist context. In this paper we critically examine some of those attempts recently made with focus on problems of the objectivity, ontology, necessity, and atemporality of mathematics. Our conclusion is that these attempts fare no better than traditional alternatives, and that they, furthermore, create new problems of their own.

Mathematical concepts are explications, in Carnap's sense, of vague or otherwise non-clear concepts; mathematical theories have an empirical and a deductive component. From this perspective, I argue that the empirical component of a mathematical theory may be tested together with the fruitfulness of its explications. Using these ideas, I furthermore give an argument for mathematical realism, based on the indispensability argument combined with a weakened version of confirmational holism.

In this paper I discuss possible ways of measuring the power of arithmetical theories, and the possiblity of making an explication in Carnap's sense of this concept. Chaitin formulates several suggestions how to construct measures, and these suggestions are reviewed together with some new and old critical arguments. I also briefly review a measure I have designed together with some shortcomings of this measure. The conclusion of the paper is that it is not possible to formulate an explication of the (...) concept. (shrink)

Herausgegeben von Walter Senner OP (Federf hrender Herausgeber), Kaspar Elm, Thomas Eggensperger OP, Isnard W. Frank OP, Ulrich Horst OP Mit neuen Methoden und Fragestellungen ist in den letzten Jahrzehnten die Erforschung der Geschichte der Bettelorden vorangetrieben und ihre ber die engere Ordens- und Kirchengeschichte hinausgehende Bedeutung f r Politik-, Wirtschafts- und Sozial-, f r Bildungs- und Geistesgeschichte herausgearbeitet worden. Zur Intensivierung und Koordinierung der sie ber hrenden Forschungen gibt die deutsche Dominikanerprovinz Teutonia die Reihe "Quellen und Forschungen zur Geschichte (...) des Dominikanerordens. Neue Folge" heraus. Auch in der Neuen Folge wird die Geschichte der Dominikaner im deutschen Sprachraum den Schwerpunkt bilden. Es werden auch wichtige Untersuchungen zur Ordensverfassung und Fr mmigkeit, zur Philosophie und Theologie aufgenommen, die f r den Dominikanerorden im Untersuchungsraum Verbindlichkeit oder Bedeutsamkeit hatten, selbst wenn die untersuchte Thematik ihrer Entstehung nach nicht speziell mit den deutschen Dominikanern und Dominikanerinnen zu tun hatte. Der Begriff Dominikanerorden wird in einem weiten Sinn verstanden. Alle Gemeinschaften, die nach rechtlicher Verfassung oder geistlicher Ausrichtung mit den Dominikanern zu tun hatten, werden ihm subsumiert: der Predigerorden, die dominikanischen Frauenkl ster und -gemeinschaften, die losen Verb nde der Dritten Orden sowie die verschiedenen Bruderschaften. Dem Zeitraum nach ist Forschungsgegenstand die Geschichte des Dominikanerordens von den Anf ngen bis in die unmittelbare Vergangenheit. Dabei ist auch gedacht an die Aufarbeitung von Entstehen und Geschichte der verschiedenen dominikanischen Frauengemeinschaften des 19. Jahrhunderts, die mit ihren religi sen und sozialen Aktivit ten in der sich rasch wandelnden Gesellschaft eine bedeutende, bisher meist untersch tzte Rolle spielten. Zum Lehrstuhl von P. Prof. Walter Senner OP: http: //philo.pust.op.org/prof/senner/index.html Zur Seite von Dr. theol. Thomas Eggensperger OP, M.A. http: //www.institut-chenu.eu. (shrink)

AbstractBackgroundEthical challenges constitute an inseparable part of daily decision-making processes in all areas of healthcare. In prehospital emergency medicine, decision-making commonly takes place in everyday life, under time pressure, with limited information about a patient and with few possibilities of consultation with colleagues. This paper explores the ethical challenges experienced by prehospital emergency personnel. MethodsThe study was grounded in the tradition of action research related to interventions in health care. Ethical challenges were explored in three focus groups, each attended by (...) emergency medical technicians, paramedics, and prehospital anaesthesiologists. The participants, 15 in total, were recruited through an internal information network of the emergency services. Focus groups were audio-recorded and transcribed verbatim.ResultsThe participants described ethical challenges arising when clinical guidelines, legal requirements, and clinicians’ professional and personal value systems conflicted and complicated decision-making processes. The challenges centred around treatment at the end of life, intoxicated and non-compliant patients, children as patients—and their guardians, and the collaboration with relatives in various capacities. Other challenges concerned guarding the safety of oneself, colleagues and bystanders, prioritising scarce resources, and staying loyal to colleagues with different value systems. Finally, challenges arose when summoned to situations where other professionals had failed to make a decision or take action when attending to patients whose legitimate needs were not met by the appropriate medical or social services, and when working alongside representatives of authorities with different roles, responsibilities and tasks.ConclusionFrom the perspective of the prehospital emergency personnel, ethical challenges arise in three interrelated contexts: when caring for patients, in the prehospital emergency unit, and during external collaboration. Value conflicts may be identified within these contexts as well as across them. A proposed model of analysis integrating the above contexts can assist in shedding light on ethical challenges and value conflicts in other health care settings. The model emphasises that ethical challenges are experienced from a particular professional perspective, in the context of the task at hand, and in a particular, the organisational setting that includes work schedules, medical guidelines, legal requirements, as well as professional and personal value systems. (shrink)

Based on a dataset of more than 5,000 contentious collective actions from 1700-2000, this paper examines the relation between popular protest and democratization of the Danish political system. The first wave of protests began in the 1830s and culminated in 1848 with the fall of absolutism and the transition to constitutional monarchy. The next protest wave from 1885 to 1887 arose from the so-called ‘constitutional struggle’ and mobilized hundreds of thousands of ordinary Danes, and contributed to the parliamentarization and nationalization (...) of the political system. The third wave unfolded around the end of World War II, while the hitherto last wave of popular struggle erupted in 1968 with the youth rebellion. The analysis show that ‘democracy’ was the central issue of contention in all four of these protest waves, and support the main thesis that periods of intense interaction between popular protest and the state have had a decisive formative influence on the genesis and further development of Danish democracy. (shrink)

Tekster til Buddhismen. Selected and translated by Frede Möller-Kristensen. Gyldendal, Copenhagen 1980. 104 pp. Illustrated. D.Kr.68.50.

In this article I will claim that from a Thomist perspective the question “Soul or Brain: What makes us human?” presents us with a false dilemma and hence must as such remain an unanswerable question. In order to corroborate this claim I will do two things. First, I present the framework of a Thomistic anthropology in so far as it relates to the unity of soul and body in the human person. Next, I deal with the question that immediately results (...) from this unity, i.e. the subsistence of the soul. From a Thomist perspective this question can be answered apart from any findings from neuroscience. (shrink)

Neurobiologically inspired theories of speech perception such as that proposed by Sussman et al. are useful to the extent that they are able to constrain such theories. If they are simply intended as suggestive analogies, their usefulness is questionable. In such cases it is better to stick with the Gibsonian approach of attempting to isolate invariants in speech and to demonstrate their role for the perceiver in perceptual experiments.