In the present book, Pauline Phemister argues against traditional Anglo-American interpretations of Leibniz as an idealist who conceives ultimate reality as a plurality of mind-like immaterial beings and for whom physical bodies are ultimately unreal and our perceptions of them illusory. Re-reading the texts without the prior assumption of idealism allows the more material aspects of Leibniz's metaphysics to emerge. Leibniz is found to advance a synthesis of idealism and materialism. His ontology posits indivisible, living, animal-like corporeal substances as (...) the real metaphysical constituents of the universe; his epistemology combines sense-experience and reason; and his ethics fuses confused perceptions and insensible appetites with distinct perceptions and rational choice. In the light of his sustained commitment to the reality of bodies, Phemister re-examines his dynamics, the doctrine of pre-established harmony and his views on freedom. The image of Leibniz as a rationalist philosopher who values activity and reason over passivity and sense-experience is replaced by the one of a philosopher who recognises that, in the created world, there can only be activity if there is also passivity; minds, souls and forms if there is also matter; good if there is evil; perfection if there is imperfection. (shrink)

Recent work in science and technology studies has looked at how chemical industries manufacture doubt about the toxicity of their products and manage to establish their scientific views in the field of international regulations on toxic substances. Rather than examining yet another “victory” for the industry, this article analyzes the deployment of a “pro-industrial” scientific position, punctuated mainly by failure and opposition. This trajectory is tracked through the analysis of several data sets: archives, scientific documentation, and sociological interviews. The (...) first part of the article charts the development of a biochemical concept, “peroxisome proliferation,” within an academic subfield and its subsequent appropriation by certain industrial parties who used it as a defensive weapon for their commercial interests. Through the example of the International Agency for Research on Cancer and its network of interdependent institutions, the article goes on to analyze the multiple attempts of chemical industry players to establish their interpretation of the concept within the regulatory bodies for carcinogenic substances. The study of such systems of sociological interdependence shows that a full analysis of the “doubt manufacturing” requires an examination not only of the manufacturing process but also of the reception of the ideas produced. (shrink)

It is standardly held that Aristotle denies that artifacts are substances. There is no consensus on why this is so, and proposals include taking artifacts to lack autonomy, to be merely accidental unities, and to be impermanent. In this paper, I argue that Aristotle holds that artifacts are substances. However, where natural substances are absolutely fundamental, artifacts are merely relatively fundamental—like any substance, an artifact can ground such nonsubstances as its qualities; but artifacts are themselves partly grounded (...) in natural substances. Many contemporary metaphysicians view authorial intentions or communal recognition as an essential feature of most artifactual kinds. Drawing on Aristotle’s own examples of artifactual definitions, I note that there is little reason to ascribe this view to Aristotle. So Aristotle has the resources to hold that it is possible that there are kinds with both artifactual and non-artifactual members. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:HUME'S USE OF ILLICIT SUBSTANCES Now as every perception is distinguishable from another, and may be consider 'd as separately existent; it evidently follows, that there is no absurdity in separating any particular perception from the mind; that is, in breaking off all its relations, with that connected mass of perceptions, which constitute a thinking being. 1. The Problem Hume is often classified as an 'atomist'. He is (...) alleged to hold that every simple perception (impression and idea) is 'independent': to say that a simple perception P. exists does not entail the existence of any other entity. As the passage above makes clear, part of this atomism is a neutral monism. That is, no perception is intrinsically mental, or material. Yet, he is also claimed to adhere staunchly to the so-called theory of ideas. Indeed, Stroud devotes the entire second chapter of his book Hume to discussion of Hume's adaptation of it. Now we shall argue that any plausible reading of the theory of ideas identifies that which is directly perceived -in Hume's case, (at least) simple perceptions -- as intrinsically mental. This means either that every perception P_ must be in some mind, thus violating one tenet of atomism, or that perceptions themselves are intrinsically mental, thus compromising their neutrality. Can Hume escape this apparent dilemma? The answer seems reasonably clear if one knows Hume. He claims that the mind is a bundle of perceptions. As a member of the bundle, a perception is mental. However, this notion of the mental is genuinely contextual; that is, no perception is, despite appearances, intrinsically mental, due to some nonrelational quality it has. To say the same thing differently, Hume holds merely that perceptions must, as a matter of fact, be 'in' minds in order to exist. Why he thinks this, according to Stroud (and others), is probably at least a function of the reasons other members of the way of ideas tradition classify the directly perceived as mental. More accurately, the following two propositions are considered to be merely contingent, i.e., non-necessary truths for Hume; one can imagine their contradictories: (1)In order to exist, a perception must be 'in' a mind, i.e., some mind or other. (2)If a person S_ has a perception P., then P_ is 'in' S., in the sense that P is a member of a collection of perceptions that constitute S_. Thus, if a perception exists, it must as a matter of fact be in some mind or other, but it is not connected necessarily to any mind. Hence perceptions are mental, yet independent i.e., neither necessarily in the collections they are in fact in, nor necessarily in any collections at all. Given (1) and (2), the existence of a perception entails the existence of a mind only in a contingent, not a logical, sense. As the reader shall see, this defense of Hume comes in the end to classifying him as some sort of phenomenalist, who reconstructs the 1 notions of mental and physical from a given data base. Ne are not satisfied with this answer. Indeed, we think it quite inadequate. To begin to show that, let us turn to a set of passages in the Treatise that set the problem we have been trying to outline. Hume himself speculates, in an infamous passage in the Appendix, that something is radically wrong with his claims about the self, that somewhere in his system there is a contradiction and, indeed, he senses that the contradiction has something to do with his atomism (T 633ff). We think he is right. Our thesis is as follows. The contradiction Hume senses is that he both holds and disavows the claim that g perceptions are mind dependent in an intrinsic sense. Thus, though a given perception is (perhaps) not necessarily in a given mind, it must either be in some mind or other in a logical sense of "must," or intrinsically mental in the sense of being intentional. As we explain in detail in section 2, the argument from perceptual variation, a cornerstone of the theory of ideas, leads inevitably to the view that there are intentional entities. Not only is... (shrink)

In this book, Carl Cranor utilizes material from ethics, philosophy of law, epidemiology, tort law, regulatory law, and risk assessment to argue that the evidentiary standards for science used in the law to control toxics ought to be ...

According to the Institute of Medicine, chronic pain affects at least 116 million adults in the United States, which is more than the total affected by heart disease, cancer, and diabetes combined. Pain costs the nation up to $635 billion each year in medical treatment and lost productivity. It has been conceptualized as a public health problem due to its prevalence, seriousness, disparities, vulnerable populations, the utility of population health strategies, and the importance of prevention at both the population and (...) individual levels. For many patients, treatment of pain is inadequate due to uncertain diagnoses, societal stigma, the lack of effective treatments, and inadequate patient and clinician knowledge about the best ways to manage pain. This article explores the inadequate treatment of pain in the U.S. and the subsequent rise of prescription painkiller abuse, misuse, and overdoses. This is followed by a review of the actions taken by states to regulate the prescribing of controlled substances. (shrink)

Medieval scholastics share a commitment to a substance-accident ontology and to an analysis of efficient causation in which agents act in virtue of their powers. Given these commitments, it seems ready-made which entities are the agents or powers: substances are agents and their accidents powers. William of Ockham, however, offers a rather different analysis concerning material substances and their essential powers, which this article explores. The article first examines Ockham’s account of propria and his reasons for claiming that (...) a material substance is essentially powerful sine accidentibus. However, the article subsequently argues that, given Ockham’s reductionism about material substance, only substantial forms – never substances – are truly agents and powers. Thus, a material substance is essentially powerful but only by courtesy – per accidens, as Ockham calls it – because it has a non-identical part, its substantial form, which does all the causal work by itself, per se. (shrink)

In this paper I discuss the role played by Ernst Mach on Nietzsche’s thought. Starting from the contents of his Beiträge zur Analyse der Empfindungen, I’ll show the close similarities between their view on both human knowledge and the scientific world description. In his writing on science Nietzsche shares Mach’s critique to the 19th century mechanism and its metaphysical ground, as much as his way of defining the substantial notions such as matter, ego and free will. Moreover, my investigation will (...) make it clear that Mach cannot be seen as a direct source of Nietzsche’s thought, since the latter wrote many times on the same subjects long before his first reading one of his works. Rather, it is possible to consider the writings of Lange, Spir and Spencer as the first sources of Nietzsche’s views on the main themes Mach dealt with in his work from 1886. (shrink)

I will in this paper attempt to extract a positive doctrine on the substantiality of the human soul from Ghazali"s critique of the Aristotelian philosophical tradition. Rather than reflecting on the possibilities and limitations of intercultural dialogue, my aim is to directly engage in such dialogue. Accordingly, I will not suppose that we need to develop and apply external standards according to which one of the two philosophical traditions addressed here, Western and Islamic, may turn out to be superior. Up (...) to a certain point, Western and Islamic philosophy are virtually indistinguishable regarding their style, the main topics, and the arguments discussed, which both take over from Aristotle and the Neoplatonists. Further, at least up to Ghazali, no Islamic philosopher actually employs standards of rationality that would differ from the standards also accepted in the West. Ghazali himself would certainly be at least as disturbed by a valid philosophical objection to his claims as any other serious philosopher. He does not pursue another kind of project, but submits to the same standards of truth and validity, as far as philosophical argument reaches. His point is, of course, that these standards do not reach as far as some philosophers suppose. But this, again, is not a particularly "Islamic� insight. (shrink)

It is widely-accepted that Descartes is a substance dualist, i.e. that he holds that there are two and only two kinds of finite substance – mind and body. However, several scholars have argued that Descartes is a substance trialist, where the third kind of substance he admits is the substantial union of a mind and a body, the human being. In this paper, I argue against the trialist interpretation of Descartes. First, I show that the strongest evidence for trialism, based (...) on Descartes' discussion of so-called incomplete substances, is highly inconclusive. Second, I show that a kind of unity (‘unity of nature’), which is had by all and only substances, is not had by human beings. The fact that the proper parts of a human being, namely a mind and a body, are of different natures entails that what they compose has at most a ‘unity of composition’. And a thing cannot be a substance in virtue of having a unity of composition. Therefore, Cartesian human beings are not substances. (shrink)

Many late medieval Aristotelians assumed that a natural substance has several substantial forms in addition to matter as really distinct parts. This assumption gave rise to a unity problem: why is a substance more than a conglomeration of all these parts? This paper discusses Francisco Suárez’s answer. It first shows that he rejected the idea that there is a plurality of forms, emphasizing instead that each substance has a single form and hence a single structuring principle. It then examines his (...) account of the relationship between matter and form. While accepting the thesis that these two parts are really distinct entities, he claimed that there is a special “mode of union” that binds them together. With this account, he defended the essential unity of a natural substance, but he transformed the program of Aristotelian metaphysics: not substances, but entities and modes inside them, are now the basic building blocks of reality. (shrink)

Computationalism treats minds as computations. It hasn't explained how our quite similar sensory circuits encode our quite different qualia, nor how these circuits encode the binding of the different qualia into unifi ed perceptions. But there is growing evidence that qualia and binding come from neural electrochemical substances such as sensory detectors and the strong continuous electromagnetic field they create. Qualia may thus be neural substances, not neural computations (though computations may still help modulate qualia). This neuroelectrical view (...) not only avoids computationalism's empirical issues but also its problematic metaphysics. (shrink)

Le Système de l'Harmonie préétablie est un système de communication. L'harmonie est une métaphore, que Leibniz reconnaît avoir empruntée à l'art ; la communication est un concept, qui, réglant les rapports perçus entre les éléments, produit et fait fonctionner le système comme tel. La notion de communication s'analyse en termes de correspondance, connexion, liaison, commerce, concomitance, accord, entr'expression (ou, figure négative, entr'empêchement). Lancée dans la controverse avec les cartésiens, elle s'applique à la relation de l'âme au corps ; mais encore (...) des corps aux corps, des substances aux substances, des âmes aux âmes, des esprits aux esprits ; mais aussi à ce qui réunit ou sépare les religions, les églises, les savoirs, les cultures. La communication traverse le système du monde comme celui des textes : elle est de physique, de métaphysique, de morale, de théologie, d'épistémologie. (shrink)

The spirits found in Arabic alchemical texts, namely zi'baq, kibrīt, nūshādir and zarnīkh are identified with their modern counterparts, which are mercury, sulfur, ammonium chloride and arsenic sulfide, respectively. Jābir's conception of spirits has been shown to be related to his practice. The puzzling experiments of Jābir on ‘mineral and organic’ spirits are compared as far as possible with modern knowledge of chemistry. These comparisons lead to an understanding of Jābir's sequence of manipulations within the logic of his alchemy. In (...) treatment of naturally occuring spirits, Jābir aimed at removing the combustibility of spirits and so improving their effect on fusible bodies. Jābir's notion of transmutation of fusible bodies is shown to be a flexible term that is equivalent to purification or reformation. (shrink)

Leibniz's views on divine concurrence have presented interpreters with great difficulty. On the one hand, Leibniz thought that creatures have genuine causal powers, causing their own states. But he also believed that God is immediately involved in every aspect of the world by endorsing the 'conservation is but continuous creation' thesis . Accordingly, when faced with the question of how divine and creaturely causality relate, Leibniz held that God and creatures concur. It is not obvious, however, how this 'concurrence' is (...) supposed to work or even whether these two commitments can be consistently maintained. ;The key challenge comes from Malebranche who argues, rather persuasively, that occasionalism follows from CCC. Leibniz, thus, needs to avoid this inference if he is to maintain real forces in creatures. In chapter two, I show how he avoids the inference by holding a restricted version of CCC. I go on to propose that Leibniz's account of concurrence is basically a cooperation model, in which God produces the modifications of creatures in accordance with the reasons presented within each creature's nature. Though God is the sole efficient cause, the creature contributes and acts in the form of rational determination, i.e., it determines which particular modification God is to produce. ;This proposal raises the worry that Leibnizian reasons are uncomfortably similar to Malebranchean occasions. In chapter three, I examine Leibniz's own attempts to distance himself from occasionalism but argue that whatever the merits of these arguments are they fall short of addressing this problem. ;Chapter four concentrates on this issue of distinguishing reasons and occasions. I argue that their core difference lies in that Leibnizian reasons demand, unlike Malebranchean occasions. This demand consists in the creature's states having an intrinsic value and this inherent goodness accounts for why they function as reasons behind God's decision to act. Furthermore, reasons as such motivate but do not necessitate and this motivating power of the goodness of reasons is a genuine power for Leibniz. For Malebranche, however, that which does not necessitate is not a cause and I conclude that this is the core difference between Leibniz and Malebranche. (shrink)

(1993). Why Olympic Athletes Should Avoid the Use and Seek the Elimination of Performance-Enhancing Substances and Practices From the Olympic Games. Journal of the Philosophy of Sport: Vol. 20, No. 1, pp. 64-81. doi: 10.1080/00948705.1993.9714504.

Although the Deweyan notion of experience has been largely developed by the pragmatist scholarship, it is surprising that its semiotic structure has been mainly overlooked. The reasons for this gap in the literature could be the fact that "semiotics" is usually associated with the work of Charles S. Peirce rather than Dewey and that Dewey never developed a general theory of signs. The aim of this paper is to introduce a semiotic reading of Dewey's theory of experience through the key (...) notion of indexical existence. I... (shrink)

One important part of Aquinas’s theory of the nature of corruptible corporeal substances is his account of the individuation of such entities. In this paper, I examine an aspect of Aquinas’s account of individuation that has not received as much attention as some others, namely, how Aquinas applies his account of individuation specifically to cases involving non-living corporeal substances. I first offer an interpretation of a key passage in Aquinas’s corpus where he explains his theory of individuation. Second, (...) I examine a text where Aquinas applies his account of individuation to a case involving non-living substances. Finally, I raise a possible objection to what Aquinas says about the individuation of non-living substances and in answering the objection suggest that Aquinas holds the view that non-living substances enjoy a less perfect mode of individuality when compared to living substances. (shrink)

In the March 2010 edition of Mayo Clinic Proceedings, Drs. Rose and Curry declared that resident physicians have an ethical duty to reduce error during periods of fatigue. Problematically, however, they argued this means ingesting a stimulant for performance enhancement and sleep avoidance during a shift when a resident physician is experiencing fatigue as the more ethical choice than forgoing ingesting a stimulant. Rather than accepting enhancement as an unstoppable technological imperative, this article will examine the underlying motivations for enhancement (...) embedded in our culture and the corresponding legal framework relating to stimulant drugs. Although our society seems to be engaged in a pharmacological arms race of efficiency, competition, and self “betterment,” the FDA has not approved stimulant drugs such as modafinil for PESA. As a result, the off-label use of modafinil for PESA means these individuals are part of a large-scale experiment that poses serious immediate and long-term side effects to the individual user as well as society. (shrink)

resumo: Este artigo pretende mostrar que sem a influência de uma filosofia construtivista que eu denomino boa, representada principalmente por Bruno Latour, a elucidação das substâncias químicas teria sido virtualmente impossível. Sem a noção de materiais “artefatuais” cunhada por eles, a Química Moderna seria impensável a partir dos metaparadigmas em uso no campo atual da história e da filosofia da ciência. A tese central que defendo aqui é a de que o construtivismo, tal como definido pelos antropológos da ciência, é (...) uma maneira disfarçada de colocar a histórica filosofia materialista na trilha da discussão histórica e filosófica das ciências e tecnologias e que isso restaura o papel desempenhado pelos materiais usados pelos cientistas para que sejam exatamente o que são. abstract: This paper aims to show that without the influence of a constructivist philosophy I call good, mainly represented by Bruno Latour, the ontological elucidation of the chemical substances would have been virtually impossible. Without the notion of artifactual materials given by them, would be Modern Chemistry unthinkable from the metaparadigms in use in the present field of history and philosophy of science. The central thesis I defended here is that constructivism as defined by the anthropologists of science is a disguised way of sliding historical materialist philosophy into the mainline of philosophical and historical discussion of the sciences and technologies and that those restore the role played by the materials used by sciences to be exactly what they are. (shrink)

This paper is devoted to the late Leibnizian doctrine of vinculum substantiale. In the first section I sketch the old problem of possibility of composite substances. This possibility is refuted on the ground of Monadism (presented in section two). However Leibniz’s correspondence with Des Bosses contains new thoughts concerning composite substances. A vinculum enters the stage as a real unifier, transforming aggregates of monads into genuine substances (section three). In the last section I give a systematic interpretation (...) of a vinculum.I start with the thesis that every composed thing, which is not a pure plurality of objects, must have two structures: the whole-parts structure and the subject-properties structure. In the case of substances the latter is ontologically prior over the former. A vinculum is a subject-of-properties (accidents) determining such a way of composition which makes a compound entity a true substance. Since Leibniz still thought a vinculum unifies independent (existentially and with regard to activity) substances he was inclined to separate a vinculum from the integrated monads and finally conceived it as an additional relatively independent monad-like substance. (shrink)

The topic of our analysis is the argument for the existence of substances given by Bernard Bolzano in Athanasia, where he essentially employs two ontological categories: substance and adherence. Bolzano considers the real and conditioned Inbegriff of all adherences, which are wirklich and nicht selbst bestehen. He claims that the formed collection is dependent on something external and non-adherential, which therefore is a substance. Bolzano’s argumentation turns out to be structurally similar to his argument for the existence of God (...) from Lehrbuch der Religionswissenschaft, but in each of these reasonings, we find different plausible interpretations of the key concept “Inbegriff”. The latter argumentation refers to the mereological totality of existentially conditioned objects. We propose the explication of the Bolzanian Inbegriff of all adherences using two types of predication: we consider its extension as composed of certain intensional counterparts of adherences. In our approach, we use a fragment of the theory of abstract objects formulated by E. Zalta, describing two different relations between individuals and properties: extensional exemplification and intensional encoding. We put our reconstruction in a wider context of Bolzano’s ontology, formulating the needed axioms with two primitive predicates of second order... is an adherence,... is conditioned by something real as well as the conditionally introduced first order predicate constant \ for Inbegriff of all adherential ideas. Finally, we sketch a model for our theory. (shrink)

This book offers a sympathetic explanation of the origin of the Theory of Forms that is true both to the dialogues and to Plato's place in history. The author's explanation makes the development of Plato's thought part of an intellectual and philosophical history that begins in the pre-Socratic period, extends through Socrates and the Sophists, and continues into the twentieth century. The explanation provides a unified reading of three passages that scholars have long recognized as keys to Plato's thought about (...) the Forms, but which have proved stubbornly resistant to interpretation, both individually and as a group: (i) the intellectual autobiography in the Phaedo; (ii) the discussion of the philosopher and the lover of spectacles in the Republic; and (iii) the discussion of starting points, the Receptacle, and the four kinds of stuff in the Timaeus. The book will be of special interest to scholars of ancient philosophy, it will also be of interest to philosophers in general, graduate students, and advanced undergraduate students. (shrink)

In Australia, the twin discoveries that resulted in Dolly the Sheep and the isolation of human embryonic stem cells in the 1990s prompted the then Minister for Health to request that the Australian Health Ethics Committee (AHEC) examine the issue of cloning and stem-cell science more closely. It is the AHEC’s job to report—in an ad hoc manner at the Minister’s request—on “any issues deemed to be pertinent to the Australian community.” Cloning and stem-cell science were big news worldwide, and (...) the Australian Government needed to be seen to act on it. What happened next was partly a reflection of the cultural values of the Australian community, and partly an expression of the social context of the use of .. (shrink)

This article aims to make further progress in revising the standard account of Wolff’s philosophy as a popularisation and systematisation of Leibniz’s doctrines. It focuses on the topic of the communication among substances and the metaphysics of simples and activity underlying it. It is argued that Wolff does not accept the pre-established harmony in its orthodox Leibnizian version. The article explains Wolff’s departure from Leibniz’s PEH as stemming from his rejection of Leibniz’s construal of the activity of every simple (...) as representational power and of the metaphysics of unity and activity in which that construal is rooted. (shrink)