Abstract

Treatment of portions of excised imaginal leg discs with an uv laser microbeam was shown to kill cells in the treated region. Treated discs cultured in the abdomens of adult females underwent pattern regulation, either regenerating, duplicating, or triplicating, depending on the precise portion of the disc which was treated. The laser-induced pattern of regulation is similar to that induced by cell removal and by cell-lethal mutations, supporting the hypothesis that pattern regulation in response to all forms of wounding is controlled by the same pattern-forming system. © 1982.