Arsenic and phosphorus are group 15 elements with similar chemical properties. Is it possible that arsenate could replace phosphate in some of the chemicals that are required for life? Phosphate esters are ubiquitous in biomolecules and are essential for life, from the sugar phosphates of intermediary metabolism to ATP to phospholipids to the phosphate backbone of DNA and RNA. Some enzymes that form phosphate esters catalyze the formation of arsenate esters. Arsenate esters hydrolyze very rapidly in aqueous solution, which makes (...) it improbable that phosphorous could be completely replaced with arsenic to support life. Studies of bacterial growth at high arsenic:phosphorus ratios demonstrate that relatively high arsenic concentrations can be tolerated, and that arsenic can become involved in vital functions in the cell, though likely much less efficiently than phosphorus. Recently Wolfe‐Simon et al. 1 reported the isolation of a microorganism that they maintain uses arsenic in place of phosphorus for growth. Here, we examine and evaluate their data and conclusions. (shrink)

In recent years, there has been tremendous growth in the amount of natural language text through various sources. Computational analysis of this text has got considerable attention among the NLP researchers. Automatic analysis and representation of natural language text is a step by step procedure. Deep level tagging is one of such steps applied over the text. In this paper, we demonstrate a methodology for deep level tagging of Malayalam text. Deep level tagging is the process of assigning deeper level (...) information to every noun and verb in the text along with normal POS tags. In this study, we move towards a direction that is not much explored in the case of Malayalam language. Malayalam is a morphologically rich and agglutinative language. The morphological features of the language are effectively utilized for the computational analysis of Malayalam text. The language level details required for the study are provided by Thunjath Ezhuthachan Malayalam University, Tirur. (shrink)

A continuoxis t- norm is a continuous map * from [0, 1]² into [0,1] such that is a commutative totally ordered monoid. Since the natural ordering on [0,1] is a complete lattice ordering, each continuous t-norm induces naturally a residuation → and becomes a commutative naturally ordered residuated monoid, also called a hoop. The variety of basic hoops is precisely the variety generated by all algebras, where * is a continuous t-norm. In this paper we investigate the structure of the (...) variety of basic hoops and some of its subvarieties. In particular we provide a complete description of the finite subdirectly irreducible basic hoops, and we show that the variety of basic hoops is generated as a quasivariety by its finite algebras. We extend these results to Hájek's BL-algebras, and we give an alternative proof of the fact that the variety of BL-algebras is generated by all algebras arising from continuous t-norms on [ 0,1] and their residua. The last part of the paper is devoted to the investigation of the subreducts of BL- algebras, of Gödel algebras and of product algebras. (shrink)

In this paper, we discuss an approach to ‘design for wow’ that focuses on the emotions that constitute a wow-experience. In this approach, the eliciting conditions of these emotions are used to define a product character with a high wow-impact. In addition to the approach, a measurable wow-index is introduced. First, a concept of wow is described in which wow is explained as a combination of fascination, pleasant surprise, and desire. The eliciting conditions of these three emotions are examined and (...) combined to a ‘wow-appraisal.’ This concept is applied in the design of a mobile telephone. A combination of qualitative and quantitative research methods was used to formulate concern themes relevant for the wow-appraisal. These themes were used to create a layered product character and a prototype of the final design. An evaluation study demonstrated that the product designed with this approach rated higher on the wow-index than alternative products. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Aristotle on the Etruscan Robbers:A Core Text of "Aristotelian Dualism"Abraham P. Bos (bio)1. A Non-Platonic Dualism in Aristotle's Lost WorksThe Soul of a Mortal on Earth is not "At Home," says Aristotle in his dialogue Eudemus. The story about the mantic dream of the expatriate Eudemus and his expectation that he "will return home"1 is well known. It makes clear that, in Aristotle's view, the death of the human (...) individual should be interpreted as the soul's "return to its homeland."2 This is strongly suggested by "the revelation of Silenus" which Plutarch (first century CE) passes down in a literal quotation from the Eudemus.3 It contains the theme of human life on earth as a punishment (timôria). The motif of human life as a punishment is central to two texts by Iamblichus (250-325 CE) and Augustine (354-430 CE), which are usually connected with Aristotle's Protrepticus.4 I want to examine these texts in more detail here. My intention in the following exposition is to propose a non-Platonistic explanation of these texts. In my opinion they have wrongly been read as testimonies of a "Platonistic" phase in Aristotle. The existence of such a phase in Aristotle's development has never been proved. Besides, the interpretation of these texts suffered from the fact that [End Page 289] Aristotle's De anima had also been explained in an unhistorical way since Alexander of Aphrodisias in the third century CE.2. Revising the Modern View of AristotleWe have to make a different assessment of Aristotle's contribution to the discussion on the soul compared with what was current until recently. For after W. Jaeger5 and F. Nuyens6, modern scholars became inclined to leave Aristotle's dialogues out of consideration, because they regarded them as "Platonizing." But a fundamental correction is necessary on this point.7 Jaeger led modern Aristotle studies in a wrong direction by assuming a sharp distinction between Aristotle's lost dialogue Eudemus and his surviving treatise De anima. Although nowadays Jaeger's theory for many scholars is something of a dead horse, nevertheless a real alternative has not been proposed. We still have to get rid of the consequences of the Jaegerian paradigm and develop a unitary interpretation of Aristotle's entire oeuvre. Even more consistently than O. Gigon has already done,8 we should assume that Aristotle's lost works and his surviving biological writings and De anima did not propose two (or more) different psychological theories but one and the same. Because this one Aristotelian psychology was a non-Platonistic but nevertheless dualistic psychology, we have much more reason than could be recognized in the past to assume Aristotelian influence on this discussion.On one essential issue Aristotle disagreed with his teacher Plato: the soul,9 more particularly the indissoluble bond of the soul with a body. Aristotle radically and [End Page 290] consistently argued for the distinction between nous and psychè.10 For Aristotle the nous-in-act is always wholly incorporeal. But he considered it characteristic of the soul that it cannot carry out its functions "without body."11However, the crucial question is: what body does Aristotle mean when he says that the soul cannot perform its specific activities "without body"? Jaeger and Nuyens were wholly convinced that Aristotle was referring to the visible, external body of a human being, animal, or plant. Hence they saw a yawning gap between Aristotle's views in De anima and his position in the dialogue the Eudemus. In the Eudemus Aristotle had clearly argued that the soul can perform its own functions very well, indeed better, without the galling and oppressive visible body.12 But in De anima II 1, in his famous definition of "the soul," Aristotle says that the soul is inextricably bound up with a "sôma physikon organikon."13 Jaeger and Nuyens, following an almost unanimous tradition since Alexander of Aphrodisias in the third century CE, interpreted this sentence in the sense that the soul is the formal principle or entelechy of an "organic body" or a "natural body equipped with organs," i.e., the visible body... (shrink)

In her paper, “The Doctrine of Double Effect: Problems of Interpretation,” Nancy Davis attempts to find an interpretation of the means-end relationship that would provide a foundation for the Doctrine of Double Effect (DDE) and its reliance on the distinction between what an agent intends or brings about intentionally and what that agent merely foresees will result from his/her action, but does not intend (or bring about intentionally). Davis’s inability to find such an interpretation lessens the plausibility of the view (...) that theDDE is an acceptable moral doctrine. In the present paper, it is suggested that Davis’s inability to find an interpretation of the means-end relationship that will support the DDE results from her assumption that an agent must intend to produce whatever he/she produces intentionally. Borrowing an argument from Michael Bratman, this article shows that Davis’s assumption is false. Thatrealization paves the way toward a defense of the DDE. (shrink)

Audio recording of "a group of Philosophical and Environmental Songs," as described by Gunter.

Schwinger’s algebra of microscopic measurement, with the associated complex field of transformation functions, is shown to provide the foundation for a discrete quantum phase space of known type, equipped with a Wigner function and a star product. Discrete position and momentum variables label points in the phase space, each taking \(N\) distinct values, where \(N\) is any chosen prime number. Because of the direct physical interpretation of the measurement symbols, the phase space structure is thereby related to definite experimental configurations.

Evolutionary developmental biology (evo-devo) has undergone dramatic transformations since its emergence as a distinct discipline. This paper aims to highlight the scope, power, and future promise of evo-devo to transform and unify diverse aspects of biology. We articulate key questions at the core of eleven biological disciplines—from Evolution, Development, Paleontology, and Neurobiology to Cellular and Molecular Biology, Quantitative Genetics, Human Diseases, Ecology, Agriculture and Science Education, and lastly, Evolutionary Developmental Biology itself—and discuss why evo-devo is uniquely situated to substantially improve (...) our ability to find meaningful answers to these fundamental questions. We posit that the tools, concepts, and ways of thinking developed by evo-devo have profound potential to advance, integrate, and unify biological sciences as well as inform policy decisions and illuminate science education. We look to the next generation of evolutionary developmental biologists to help shape this process as we confront the scientific challenges of the 21st century. (shrink)

Sorokin, Pitirim Alexandrovich, born January 21,1889, in the small village of Turia in Russia [died 1968]. Student at the Teachers' Seminary in the province of Kostroma in Russia, at the evening school in St. Petersburg, at the Psycho- Neurological Institute in St. Petersburg ; Magistrant of Criminal Law ; Ph.D in Sociology ; Privatdozent at the Psycho-Neurological Institute, at the University of St. Petersburg ; Professor of Sociology at the same university ; Professor of Sociology at the Agricultural Academy, at (...) the University of Minnesota ; Chairman of the Department of Sociology at Harvard University from 1930. Member of the Executive Committee of the All-Russian Peasant's Soviet ; Secretary to the Prime Minister [ Kerensky ] ; member of the Russian Constitutional Assembly ; sentenced to death and finally exiled by the communist administration ; emigrated to the United States, naturalized. Member of the American Academy of Arts and Sciences, the American Sociological Association; honorary member of the International Institute of Sociology of the Czechoslovakian Academy for Agriculture, of the German Sociological Society, and of the Ukrainian Sociological Society; President of the International Institute for Sociology. Member of the Greek-Orthodox Church. (shrink)