The medial temporal lobe supports both navigation and declarative memory. On this basis, a theory of phylogenetic continuity has been proposed according to which episodic and semantic memories have evolved from egocentric and allocentric navigation in the physical world, respectively. Here, we explored the behavioral significance of this neurophysiological model by investigating the relationship between the performance of healthy individuals on a path integration and an episodic memory task. We investigated the path integration performance through a proprioceptive Triangle Completion Task (...) and assessed episodic memory through a picture recognition task. We evaluated the specificity of the association between performance in these two tasks by including in the study design a verbal semantic memory task. We also controlled for the effect of attention and working memory and tested the robustness of the results by including alternative versions of the path integration and semantic memory tasks. We found a significant positive correlation between the performance on the path integration the episodic, but not semantic, memory tasks. This pattern of correlation was not explained by general cognitive abilities and persisted also when considering a visual path integration task and a non-verbal semantic memory task. Importantly, a cross-validation analysis showed that participants' egocentric navigation abilities reliably predicted episodic memory performance. Altogether, our findings support the hypothesis of a phylogenetic continuity between egocentric navigation and episodic memory and pave the way for future research on the potential causal role of egocentric navigation on multiple forms of episodic memory. (shrink)

The internet is widely used for health information and support, often by vulnerable people. Internet-based research raises both familiar and new ethical problems for researchers and ethics committees. While guidelines for internet-based research are available, it is unclear to what extent ethics committees use these. Experience of gaining research ethics approval for a UK study (SharpTalk), involving internet-based discussion groups with young people who self-harm and health professionals is described. During ethical review, unsurprisingly, concerns were raised about the vulnerability of (...) potential participants. These were dominated by the issue of anonymity, which also affected participant safety and consent. These ethical problems are discussed, and our solutions, which included: participant usernames specific to the study, a closed website, private messaging facilities, a direct contact email to researchers, information about forum rules displayed on the website, a ‘report’ button for participants, links to online support, and a discussion room for forum moderators. This experience with SharpTalk suggests that an approach to ethics, which recognises the relational aspects of research with vulnerable people, is particularly useful for internet-based health research. The solutions presented here can act as guidance for researchers developing proposals and for ethics committees reviewing them. (shrink)

Clinical ethics consultants should show bold moral courage in discharging their duties to patients, families, and healthcare providers. Given the corrosive impact on trust, and on the appropriate d...

In response to concern over the numeracy skills deficit displayed by student nurses, an online computer programme, ?Authentic World??, which aims to simulate a real-life clinical environment and improve the medication dosage calculation skills of users, was developed (Founded in 2004 Authentic World Ltd is a spin out company of Glarmorgan and Cardiff Universities, Cardiff, Wales UK.). Two randomised controlled trials were conducted, each at a UK University, in order to investigate the impact of Authentic World? on student nurses? general (...) numeracy abilities. All first year nursing students who gave consent were randomised equally into an intervention or control group. The intervention group were given access to Authentic World?. The primary outcome measure was the students? scores on a general numeracy test. The Intention to Treat (ITT) analysis in both trials revealed a small negative effect of Authentic World? on general numeracy, which was statistically significant in one trial. However, compliance with the intervention was very low in both trials, with only 24 and 12% of students allocated to the intervention groups spending more than 15 minutes using the programme. Providing nursing students with access to Authentic World? is not an effective use of resources since use of the programme appears to be very low. (shrink)

Volume 25, Issue 2, February 2025, Page 132-134.

Multidisciplinary healthcare committees meet regularly to discuss patients’ candidacy for emerging functional neurosurgical procedures, such as Deep Brain Stimulation . Through debate and discussion around the surgical candidacy of particular patients, functional neurosurgery programs begin to mold practice and policy supported both by scientific evidence and clear value choices. These neurosurgical decisions have special considerations not found in non-neurologic committees. The professional time used to resolve these conflicts provides opportunities for the emergence of careful, ethical practices simultaneous with the expansion (...) of therapy applications. (shrink)

The purpose of this study was to evaluate, revise, and extend the Informed Consent Ontology (ICO) for expressing clinical permissions, including reuse of residual clinical biospecimens and health data. This study followed a formative evaluation design and used a bottom-up modeling approach. Data were collected from the literature on US federal regulations and a study of clinical consent forms. Eleven federal regulations and fifteen permission-sentences from clinical consent forms were iteratively modeled to identify entities and their relationships, followed by community (...) reflection and negotiation based on a series of predetermined evaluation questions. ICO included fifty-two classes and twelve object properties necessary when modeling, demonstrating appropriateness of extending ICO for the clinical domain. Twenty-six additional classes were imported into ICO from other ontologies, and twelve new classes were recommended for development. This work addresses a critical gap in formally representing permissions clinical permissions, including reuse of residual clinical biospecimens and health data. It makes missing content available to the OBO Foundry, enabling use alongside other widely-adopted biomedical ontologies. ICO serves as a machine-interpretable and interoperable tool for responsible reuse of residual clinical biospecimens and health data at scale. (shrink)

As neural implants transition from engineering design and testing into human subjects research, careful consideration must be paid to the ethical elements in developing research protocols. Although these ethical aspects may be framed by the design choices of the engineering, a number of challenging choices arise. In spite of many ethical considerations for neural implant technologies being shared with generic research ethics questions, there are subsets needing special attention. Even in considerations requiring increased attention, substantial overlap can be found with (...) research ethics questions for general medical implants and for psychiatric pharmaceuticals. The special attention to specific ethical questions in neural implants exists because of the value placed on preserving cognition and control as well as our continued memory of significant past research abuses in neurosurgery. This paper focuses on three issues of particular saliency to neural implant testing: inclusion/exclusion of subjects with psychiatric conditions, consent withdrawal of research subjects, and enhancement as a goal. (shrink)

Supported decision making, as outlined by Peterson et al. highlights real-world challenges in the messy context of clinical care. We agree with Peterson et al. that patients...

The language of science goes from description ton explanation; the first one is concerned in telling how phenomena happen and the second one to tell why they happen. This article explores two postures within science: the descriptive and the explanatory.

This essay pretends to bring to discussion some ideas for the clearing of the concept of measurement, and, from there, to the discussion of the nature of variables and their scales.

Valeroso ha sido el esfuerzo de Arno Münster, filósofo franco-alemán, profesor de la Universidad de Amiens, por hacer conocer la obra de Ernst Bloch. Esta lucha, larga de muchos años de enseñanza e investigación, a veces solitaria, a veces a contracorriente de ciertas tendencias dominantes en la filosofía universitaria continental europea, se materializa una vez más con ocasión de la publicación de su último libro que reagrupa de una serie de conferencias de diverso contenido temático sobre el pensamiento de Bloch, (...) pronunciadas en distintos escenarios a lo largo de los últimos cinco años. La primera, establece una especie de cuadro comparativo entre la idea de “comprenderse a sí mismo en la existencia” de Kierkegaard, el concepto de angustia en Heidegger y la ontología del todavía-no de Bloch. (shrink)

La abandonada cuestión del sujeto histórico desde la des-construcción meramente negativa y algo superficial de los mega-relatos propios de la filosofía moderna culminante, retoma su actualidad filosófica en el momento de la denominada globalización, coincidente con una general decadencia de la cultura y de la responsabilidad políticas. La mencionada cuestión es acuciante para quienes, por diversas razones, no se conforman con el desconcierto o no pueden quedar conformados en él, sea por la conciencia de la tarea que la existencia histórica (...) implica, sea por el apremio que recibe su posición de algún modo determinante en la historia contemporánea. El A. aborda el tema desde un planteo preliminar -dividido en dos partes- que intenta primero demostrar, desde el actual redimensionamiento de la decisiva importancia de la sociedad civil para una democracia viva, la necesidad de abordar el sentido de la configuración del sujeto histórico; en segundo lugar, muestra lo decisivo de una recapitulación, en paralelo con lo anterior, de la experiencia fundante y de las tesis básicas que determinaron el potente resurgimiento moderno de esta cuestión, bajo el signo del "sujeto colectivo", para deslindar el horizonte de un nuevo tratamiento de la misma. The abandoned issue of the historical subject since the merely negative and somewhat superficial de-construction of the mega-narration proper of the uppermost modern philosophy, retakes its philosphical actuality at the moment of the so called globalization, coincident with a general decadence of the political culture and responsability. This matter is pressing for those who, for different reasons, do not adjust themselves to the bewilderment or cannot agree with it, either because of the concience of the task that historical existence implies, or because of the pressure that its position, in some way determinating, recieves in contemporary history. A. approaches the subject from a preliminary raising of the -divided in two parts- that tries to demonstrate first, from the actual redimensioning of the decisive importance of the civil society for an alive democracy, the necesity to approach the sense of the configuration of the historical subject; secondly, it shows the decisiveness of a recapitulation, in connection with the previous matter of the founding experience and of the basic theses that determinated the powerful modern revival of this question, under the sign of the "colective subject", to define the horizon of a new tratement of it. (shrink)

Se intenta desarrollar el movimiento de pensamiento que conforma el libro Libertad, Poder y Discurso del filósofo santafesino Julio De Zan, dentro de la línea de la racional dad comunicativa y de la ética del discurso de Habermas y Apel, redefinidos a partir de la problemática político-cultural latinoamericana, del debate entre modernidad y post-modernidad y en orden a una democratización estructural de las sociedades. Se exponen los núcleos y pasajesargumentativos para un diálogo productivo en orden a la superación de las (...) raíces de la "subjetividad egocéntrica" y su ideal ético-político plasmado en la cultura dominante y en las evidencias del actual proyecto de un "nuevo orden mundial".En una primera parte se delinean los momentos de la actual crisispolítico-cultural, con especial énfasis en la crisis de la racionalidad que no alcanza a ser superada, sino que es más bien profundizada, por las formas restaurativas, postmodernas y positivistas de discurso.En una segunda parte se ponen de relieve los momentos superadores elaborados desde dentro de la situación de crisis. Planteando una reconstrucción de Ja fuerza de la racionalidad dialectizable con Jos significados de las culturas efectivas; reelaborando comunicativamente el significado específico del poderpolítico y, finalmente, diseñando el valor ético de la democracia participativa como régimen político de la libertad positiva. En un próximo artículo se indicarán algunos puntos de discusión sobre la base del horizonte de reflexión abierto por este provocante libro. (shrink)

Partindo do questionamento acerca daorigem da confiança de Agostinho na objetivida-de inerente à subjetividade humana, ligada essen-cialmente à pergunta pela verdade, o autor desen-volve o modo como Agostinho realiza a passagemdo não-eu para 0 eu, enfocando a investigação deAgostinho sobre a liberdade do ser humano e so-bre a perda da liberdade, bem como o modo comoo ser humano experimenta o desejo, a desordeme a violência do seu próprio eu, podendo perdê-lo.

Resumen: La concepción dominante en ámbitos artísticos y académicos del ritmo está atravesada por una definición que prioriza aspectos numéricos como la repetición, la duración y la división proporcional del tiempo y los acontecimientos, la sobrevaloración de los aspectos métricos en relación a otros componentes del fenómeno rítmico, además de una obsoleta teorización mono-disciplinar por la cual se lo piensa como si fuera un fenómeno cuyas características no son comparables en sus manifestaciones en - Danse, théâtre et spectacle vivant – (...) GALERIE – Nouvel article. (shrink)

Ce texte a déjà paru dans Telondefondo. Revista de Teoria y Critica Teatral, n° 9, julio, 2009. Nous remercions Aníbal Zorrilla de nous avoir autorisé à le reproduire sur RHUTHMOS.: The artistic works that cross different languages present a particular phenomenon because of the folds, ambiguities and juxtapositions they offer. The analysis of their rhythmic aspects and the mechanism used by rhythm to bring meaning in this kind of works, requires a new notional frame ; it is necessary - (...) Danse, théâtre et spectacle vivant – GALERIE – Nouvel article. (shrink)

A breathtaking detective story, this book charts the adventure of Whitehead's ideas in a remarkably detailed and careful reconstruction of his metaphysical views.

Aníbal Pineda Canabal: Sabemos que Ernst Bloch sentía aversión por la biografía, pero el camino de los estudiosos de un pensamiento, a veces, funciona también de traición en traición.

This study examines how the self-reported cheating behaviors of students from a single large institution serving primarily adult students in online courses differ from those previously reported in large-scale studies of academic integrity among traditional-age college students. Specifically, the research presented here demonstrates that students at a large online university are no more likely to engage in most forms of cheating than the traditional-age students in residential institutions studied by Donald McCabe in his seminal research on academic integrity. Relatedly, our (...) study finds that students’ age decreases the likelihood of engaging in cheating behaviors. Moreover, traditional-age undergraduates in our study were no more likely to engage in cheating behaviors than the undergraduate students McCabe surveyed. Our study offers a unique contribution to the extant literature on academic integrity, as we believe this is the largest survey of student attitudes, beliefs, and behaviors from a single institution. The research presented here confounds the common perception that cheating is more prevalent and easier to accomplish in online learning and assessment. (shrink)

In the first monograph on Lyotard and education, Derek R. Ford approaches Lyotard's thought as pedagogical in itself. The result is a novel, soft, and accessible study of Lyotard organized around two inhuman educations: that of "the system" and that of "the human." The former enforces an interminable process of development, dialogue and exchange, while the latter finds its force in the mute, secret, opaque, and inarticulable. Threading together a range of Lyotard's work through four pedagogical processes-reading, writing, voicing, (...) and listening-the author insists on the distinct educational logics that can uphold or interrupt different ways of being-together in the world, touching on a range of topics from literacy and aesthetics to time and political-economy. While Inhuman Educations can serve as an introduction to Lyotard's philosophy, it also constitutes a singular, provocative, and fresh take on his thought. (shrink)

The present work intends to investigate about explanation models related to the evolution concept in school texts in Argentina, using categories proposed by Bar (2005). The reconstructed model shows characteristics of adaptation systems, models that give account of biological phenomena with end..

En este artículo se revisan los conceptos principales de la metodología cuantitativa, considerando el contexto histórico de la ciencia en Latino América y se presentan las áreas del conocimiento que se nutren de estudios de tipo cuantitativo en Latino América en revistas de investigación.In this essay it is reviewed the main concepts of quantitative methodology, considering the historical context of science in Latin America and it is showed the areas of knowledge that use quantitative studies in Latin American in journals.

Social Research can be made both from an analytical conception or from a systemic conception. In the first, the system is divisible in its parts, which keep the properties of the system. In the second, the system constitutes a hole which cannot be re-constituted from the properties of the mere sub-..

En el presente trabajo analizamos la novela Un verdor terrible (2020) de Benjamín Labatut como un texto que dialoga con las representaciones en torno al Antropoceno. A partir de este contexto geológico y planetario comprendemos la monstruosidad de los científicos y de la ciencia en términos de literatura gótica. La monstruosidad de la ciencia se produce por la ruptura de los marcos de representación, lo que construye una estética anamórfica cercana a las formas en que el arte puede aniquilar al (...) sujeto de la representación según el psicoanálisis. Estos dos hilos, antropoceno y goticidad, los tejemos para señalar la intrusión e insurgencia de Gaia dentro de la novela como factor desestabilizador de los afectos. (shrink)

We are in the midst of an unprecedented, human-caused, environmental crisis.

Ponencia inédita presentada en el II Congreso Internacional de Teatro, Buenos Aires 12 al 15 de octubre 2011. Instituto de Investigación en Teatro Departamento de Artes Dramáticas, Universidad Nacional de las Artes. Ritmo y lenguaje Muchos autores estudian el ritmo en el lenguaje en general, y especialmente en textos literarios. La mayor parte de ellos, especialmente quienes tratan sobre la poesía, discrimina particularmente el aspecto métrico por un lado, en el cual el número de sílabas y la - Poétique et (...) Études littéraires – GALERIE – Nouvel article. (shrink)

The first complete sequence of an archaebacterial genome, that of Methanococcus jannaschii, has recently been published(1). Less than half of the open reading frames (ORFs) can be assigned a function based on similarity to known sequences in databases. These assignable ORFs fall into two general classes; those involved in transcription, translation and replication are more similar to eukaryotic homologs, while those determining metabolic processes are more similar to eubacterial versions. The immense but very rewarding task of making biological and evolutionary (...) sense of all this information has only just begun. (shrink)

The article reflects, 1) by way of introduction, on the ontological dimension of event, starting from a phenomenology of birth, as a key to a methodological widening of the exercising of reason and to a broadening of its subject-matter. With this aim, and as a whole, this article moves mainly through the thought of Claude Romano, also picking up precise commentaries of Paul Ricoeur's and Romano Guardini's. Then, it deals with the difference and the relation between "fact" and "event", briefly (...) analyzing the theme's anticipation in decisive instances of philosophical tradition, in which reason's competence is acclaimed . 3) Inasmuch as being born from and for event, concerns appropriately only the self [as I], an inquiry about the rigorous and non transferable conceptual meaning corresponding to the word "self"[as I] is carried out, starting from the experience of self: transcendental and existential. Event, inherent to the complete human dynamics, opens finitude up from top to bottom, and is, as such, transgression of the totality of existence in finitude ; this derives into the correlation of event, transfiguration of the world and exceptionality of the self as upcoming. 5) The mutual implication among ontology of birth, broadening of reason and expansion of freedom finally leads to reflect upon the enigma of ipseity, which is impossible starting from sameness and only eventual from alterity/otherness. The bond between alterity and birth raises the issue of the relation, as regards the [subject] arrived-at-the-world, between the history and his/her history. Being born and existing in the ontological dimension of event is to exceed every power of appropriation, self- as much as others'. In reference to the alterity of the immemorial and non appropriable past, birth opens the upcoming self up to a prospect further than any project, and in doing so, takes the base off future-to-come, to which no limit can be set for it belongs to the regime of event.El artículo reflexiona, 1) a modo de introducción, sobre la dimensión ontológica del acontecimiento, desde una fenomenología del nacimiento, como clave para una ampliación metodológica y temática del ejercicio de la razón. El conjunto de este artículo transita, para ello, principalmente a través del pensamiento Claude Romano, retomando también puntuales acotaciones de Paul Ricoeur y Romano Guardini. 2) Trata luego la diferencia y la relación entre "hecho" y "acontecimiento", analizando brevemente la anticipación del tema en instancias decisivas de la tradición filosófica, donde la competencia de la razón es exaltada . 3) Puesto que nacer desde y para el acontecimiento concierne propiamente sólo al yo, se indaga sobre el significado conceptual riguroso e intransferible correspondiente a la palabra "yo", a partir de la experiencia de sí: trascendental y existencial. 4) El acontecimiento, inherente a toda la dinámica humana, abre de punta a punta la finitud y, como tal, es transgresión de la totalización de la existencia en la finitud ; esto deriva en la correlación entre acontecimiento, transfiguración del mundo y excepcionalidad del yo, como adveniente. 5) La mutua implicación entre ontología del nacimiento, ampliación de la razón y expansión de la libertad conduce, finalmente, a reflexionar sobre el enigma de la ipseidad imposible desde la mismidad y sólo eventual desde la alteridad. El vínculo entre alteridad y nacimiento plantea la relación, en el venido-al-mundo, entre la historia y su historia. Nacer y existir en la dimensión ontológica del acontecimiento es exceder todo poder de apropiación, propia y de otros. Referido a la alteridad del pasado inmemorial e inapropiable, el nacimiento abre el adveniente a un porvenir más adelante que todo proyecto y, así, desfonda también el porvenir, al que no se puede poner límite porque está en régimen de acontecimiento. (shrink)

In their latest target article, Zilio and Lavazza (2023) major claim is that research on human cerebral organoids (HCOs) must take into account whether they can acquire sentience or a primitive for...

An outstanding group of leaders left evidence that a richer and more sustainable democracy could be achieved with American independence and democratic principles integrated into a new republican form of government. They were moved by principles that are the very spirit of democracy. These principles are needed to enhance democracy and improve well-being. Using the constructivist tradition of grounded theory and Aristotle’s conception of abstraction, the article proposes a theory of the first principles of democracy based on substantive data: the (...) Declaration of Independence, the Articles of Confederation, The Federalist Papers, and the United States Constitution. Knowledge, fairness, human dignity, hope, unity, and security are the first principles of democracy and are regarded as the bedrock of democracy and a government framework for the people. This theory contributed to a formal model of democratic social change. It also contributes a conceptual framework that supports Solum’s semantic originalism, a theory of constitutional interpretation. The principles of democracy can revitalize democracy and provide new possibilities by protecting education as an innate human right, abolishing capital punishment, criminalizing private prisons on the stock market, and reevaluating the proportionality of prison sentences. (shrink)

There have been 417 gun violence in schools since Columbine. In these shootings, more than 383,000 students were killed. At the time of the event, most offenders of school mass shootings were targets of school bullying, experiencing a mental health crisis, and a history of depression. Effective interventions and support that could help prevent or reduce school bullying incidents require understanding the process of demoralization and empowering social change. This paper is part of an original constructivist grounded theory study on (...) democratic social change in America explored through a post hoc polytheoretical framework comprised of Foucauldian, Bourdieuan, and Marxist power. It aims to answer the question: In which areas would the democratic social change grounded theory resonate the most? Of significance was the finding of a novel framework from which to understand and assess how students unknowingly use power strategies that could lead to the demoralization of targets of bullying who lack adequate coping skills and meaningful support and an empowering social change process that could counter demoralization and lead to security. More research is needed on bully-involved demoralization and specific interventions that lead to positive and sustainable social change. (shrink)

Great Britain subjugated colonists using various power strategies, including dehumanization, misinformation, fear, and other divisive strategies. The Founders described these oppressive strategies as “a long train of abuses and usurpations.” Throughout the Declaration of Independence and the U.S. Constitution, the Founding Fathers imbued the people with hope in a government for the people: one unlike that of the monarchy, which sought to protect itself at the expense of colonists. As a result, the Founders created a government more likely to lead (...) with fairness, demonstrate respect for human dignity, unite Americans as one people, empower citizens through hope, and lead the nation toward security. This socio-ethical framework was an abductive discovery nested within a grounded theory study where it had been concluded that the first principles of democracy were woven within the American founding documents. Using Charmaz’s constructivist grounded theory, the first principles of democracy—knowledge, fairness, human dignity, hope, unity, and security—were used to answer an emerging research question: Are there two democratic frameworks in the founding documents, and how do they differ? The first principles of democracy promote a culture of ethics, resilience, and freedom. Their empowering disposition makes them suitable as a normative framework for a democratic government for the people. (shrink)