Los libros plúmbeos del Sacromonte forman un audaz intento de resistencia intelectual e intervención en el pensamiento cristiano por parte de la comunidad morisca granadina. Tomando elementos tanto de la proliferación pseudoprofética en la España del XVI como de la visión islámica de la historia de las religiones, se crean unos textos que aunque islámicos en su mensaje final, pueden ser aceptables tanto para cristianos como para musulmanes, especialmente a partir de las traducciones realizadas de los textos árabes. Este intento (...) cristalizaría con esa "Verdad del Evangelio" anunciada en el Sacromonte, que se materializa en el Evangelio de Bernabé, cuyas similitudes con los libros plúmbeos son numerosas, y que presenta lo que desde el punto de vista del Islam podría ser un relato de la vida y mensaje de Jesús antes de las alteraciones efectuadas por el cristianismo. (shrink)

Background In the EU, clinical assessors, rapporteurs and the Committee for Medicinal Products for Human Use are obliged to assess the ethical aspects of a clinical development program and include major ethical flaws in the marketing authorization deliberation processes. To this date, we know very little about the manner that these regulators put this obligation into action. In this paper, we intend to look into the manner and the extent that ethical issues discovered during inspection have reached the deliberation processes. (...) Methods To gather data, we used the Dutch Medicines Evaluation Board database and first searched for the inspections, and their accompanying site inspection reports and integrated inspection reports, related to central marketing authorization applications of drugs submitted to the European Medicines Agency from 2011 to 2015. We then extracted inspection findings that were purely of ethical nature, i.e., those that did not affect the benefit/risk balance of the study. Only findings graded at least major by the inspectorate were included. Lastly, to identify how many of the ethically relevant findings reach the application deliberation processes, we extracted the relevant joint response assessment reports and reviewed the sections that discussed inspection findings. Results From 2011 to 2015, there were 390 processed applications, of which 65 had inspection reports and integrated inspection reports accessible via the database of the Dutch Medicines Evaluation Board. Of the 65, we found ERFs in 37. The majority of the ERFs were graded as major and half of the time it was informed-consent related. A third of these findings were related to research ethics committee processes and requirements. Of the 37 inspections with ERFs, 30 were endorsed in the integrated inspection reports as generally GCP compliant. Day 150 joint response assessment reports and Day 180 list of outstanding issues were reviewed for all 37 inspections, and none of the ERFs were carried over in any of the assessment reports or list of outstanding issues. Conclusion None of the ethically relevant findings, all of which were graded as major or critical in integrated inspection reports, were explicitly carried over to the joint assessment reports. This calls for more transparency in EMA application deliberations on how ERFs are considered, if at all, in the decision-making processes. (shrink)

In this work we will take up again the contributions of the feminist philosophy of science around androcentrism, with special emphasis on biology and biomedical sciences. We will propose that such contributions can be ordered according to three different senses of androcentrism, and that important tensions appear between these senses. Following the path traced by Longino, contextual critical empiricism, we will defend that the rational reconstruction of theories can help us to specify where patriarchal decision vectors crouch in scientific practice. (...) To this end, we will present an alternative analysis to Longino’s and use it as an input to discuss the idea of type brains in the framework of the neuroendocrinology of behaviour. (shrink)

Die Bibliotheca Teubneriana, gegründet 1849, ist die weltweit älteste, traditionsreichste und umfangreichste Editionsreihe griechischer und lateinischer Literatur von der Antike bis zur Neuzeit. Pro Jahr erscheinen 4-5 neue Editionen. Sämtliche Ausgaben werden durch eine lateinische oder englische Praefatio ergänzt. Die wissenschaftliche Betreuung der Reihe obliegt einem Team anerkannter Philologen: Gian Biagio Conte (Scuola Normale Superiore di Pisa) Marcus Deufert (Universität Leipzig) James Diggle (University of Cambridge) Donald J. Mastronarde (University of California, Berkeley) Franco Montanari (Università di Genova) Heinz-Günther Nesselrath (Georg-August-Universität (...) Göttingen) Dirk Obbink (University of Oxford) Oliver Primavesi (Ludwig-Maximilians Universität München) Michael D. Reeve (University of Cambridge) Richard J. Tarrant (Harvard University) Vergriffene Titel werden als Print-on-Demand-Nachdrucke wieder verfügbar gemacht. Zudem werden alle Neuerscheinungen der Bibliotheca Teubneriana parallel zur gedruckten Ausgabe auch als eBook angeboten. Die älteren Bände werden sukzessive ebenfalls als eBook bereitgestellt. Falls Sie einen vergriffenen Titel bestellen möchten, der noch nicht als Print-on-Demand angeboten wird, schreiben Sie uns an: [email protected] Sämtliche in der Bibliotheca Teubneriana erschienenen Editionen lateinischer Texte sind in der Datenbank BTL Online elektronisch verfügbar. (shrink)

The paper deals with of one aspect of “The Laws”: the rules proposed on partying, drinking and the type of music and dance presided over by Dionysus. The Athenian tries to combine: a) the need for education to form law-abiding citizens capable of defending the city; b) the need to control the disturbing effects of drinking and debauchery on music and dance; and c) the desire to maintain the Athenian tradition they were proud of: the conciliation of military excellence and (...) the fun produced by drinking, music and dance. (shrink)

The paper presents Amartya Sen’s critique of the anthropological model that underlies the conception of neoclassical economics, in order to present the conception of subject offered by the abilities approach and then the notion of development as freedom.

BackgroundIn research ethics, the most basic question would always be, “which is an ethical issue, which is not?” Interestingly, depending on which ethics guideline we consult, we may have various answers to this question. Though we already have several international ethics guidelines for biomedical research involving human participants, ironically, we do not have a harmonized document which tells us what these various guidelines say and shows us the areas of consensus. In this manuscript, we attempted to do just that.MethodsWe extracted (...) the imperatives from five internationally-known ethics guidelines and took note where the imperatives came from. In doing so, we gathered data on how many guidelines support a specific imperative.ResultsWe found that there is no consensus on the majority of the imperatives and that in only 8.2 % of the imperatives were there at least moderate consensus. Of the 12 clusters, Informed Consent has the highest level of consensus and Research Collaboration and Regulatory Sanctions have the least.ConclusionThere was a lack of consensus in the majority of imperatives from the five internationally-known ethics guidelines. This may be partly explained by the differences among the guidelines in terms of their levels of specification as well as conceptual/ideological differences. (shrink)

The use in psychology of crowdsourcing platforms as a method of data collection has been increasing in popularity because of its relative ease and versatility. Our goal is to adapt the Gratitude Questionnaire–20 Items to the English language by using data collected through a crowdsourcing platform. The G20 is a comprehensive instrument that takes in consideration the different basic processes of gratitude and assesses the construct’s cognitive, evaluative, emotional, and behavioral processes. We test the psychometric properties of the English version (...) of the G20 with a Prolific user sample. We assess the adequacy of the G20 for the crowdsourcing population in its English version. A description of the characteristics of the participants is conducted. Reliability analyses reveal an optimal internal consistency of the adapted scale. The results are discussed from a cross-cultural vision of gratitude. We conclude that the Gratitude Questionnaire–20 Items, adapted to English with an American sample, is a psychometrically strong instrument to measure gratitude using crowdsourcing platforms for data collection and, therefore, a reference and useful tool in future research. (shrink)

Es muy posible que en más de una ocasión hayamos oído expresiones como ¡Si no está de acuerdo con tal decisión de la jerarquía eclesial que se vaya! O bien, ¡La Iglesia no es un club! En el fondo de ambas expresiones y de otras que hablan sobre la pertenencia a la Iglesia hay una precomprensión de lo que es ésta y lo que implica su pertenencia a ella. En algún caso parece pensarse que la Iglesia es un club fundado (...) por Jesucristo que estableció unos estatutos imposibles de modificar que al entrar te comprometes a acatar y que quien no está de acuerdo puede entregar el carné e irse porque las normas están claras, o dicho de otro modo que la Iglesia es una "entidad" tan especial que no tiene nada que ver con la decisión personal y comunitaria de sus integrantes. En el fondo estamos ante un tema de gran importancia como es la pertenencia grupal y su dinámica. (shrink)

El escrito tiene como objetivo reflexionar sobre la entrevista narrativa como una posibilidad teórica de comprender el procedimiento adecuado para desarrollar una investigación biográfico narrativa en torno a las trayectorias académicas de unos profesores de tiempo completo que laboran en un programa doctoral a los que denomino académicos porque hacen las funciones sustantivas de investigación, docencia y difusión de sus investigaciones, además de gestión y vinculación como funciones adjetivas. La reflexión se tematiza a partir de participar en un seminario permanente (...) sobre la Narrativa y subjetividad en investigación en educación. También se vincula con mi investigación en proceso denominada egresados del doctorado del ISCEEM. Relatos de trayectorias académicas, identidad y subjetividades. La reflexión se enmarca tratando de pensar con dos autores centrales Antonio Bolivar sobre la investigación biográfico narrativa y Hugo Zemelman sobre el sujeto social que deviene en sujeto académico. (shrink)

The topic of mixed emotions has received considerable attention in recent years. However, two limitations in this research are the lack of (a) theoretical prediction regarding the types of conditions likely to cause one emotion to yield to another, and (b) attention given to the moment-to-moment (MTM) experience of mixed emotions. Using the empirical context of competitive contests, the mixed emotions state of suspense was manipulated in a series of studies designed to address these shortcomings. The results indicate that the (...) most appropriate emotion pair to describe suspense is hope and fear. In addition, we find that the juxtaposition of these two emotions over the temporal sequence relies on viewers’ interpretation of observed events relative to a preferred outcome. The results indicate a prevalence of bipolarity between hope and fear at lower levels of suspense and bivariance at higher levels. Given a high-suspense episode, both hope and fear are activated; whereas when suspense is low, hope (fear) is ascendant and fear (hope) declines when it becomes obvious a preferred competitor will ultimately win (lose). (shrink)

BackgroundIn this manuscript, we argue that within the context of phase IV, physician-researchers retain their fiduciary obligation to treat the patient-participants.DiscussionWe first clarify why the perspective that research ethics ought to be differentiated from clinical ethics is not applicable in phase IV, and therefore, why therapeutic orientation is most convivial in this phase. Next, assuming that ethics guidelines may be representative of common morality, we show that ethics guidelines see physician-researchers primarily as physicians and only secondarily as researchers. We then (...) elaborate on what a fiduciary obligation is and how some of the obligations are default duties. Lastly, we look at the fiduciary obligation of the physician-researcher in phase IV interventional trials.ConclusionThe fiduciary obligation to treat is not as easily waived as in earlier trials. Assuming the entwinement of research and practice in phase IV, physician-researchers, in collaboration with other researchers, investigators, and research ethics committees, should ensure that in terms of study design, methodology, and research practice, the therapeutic value of the research to the patient-participants is not diminished. (shrink)

Tem-se analisado, recorrentemente, a influência de Homero e de Hesíodo no proêmio do poema de Parmênides. As possíveis influências da poesia órfica tem sido apenas consideradas. Todavia, diversas descobertas de textos órficos aconselham voltar a analisar os vestígios da tradição mistérica, em geral, e órfica, em particular, no poema do filósofo de Eléia, sem minimizar, com isso, as outras influências já postas em relevo. O autor assinalou, em um trabalho anterior, algumas conexões entre Parmênides e os textos órficos; neste artigo, (...) a análise se centra nos pontos de contato com ideias e imagens literárias dos Mistérios que se encontram no proêmio. Não se trata de determinar as crenças do filósofo, senão de situar, no âmbito da tradição, os conteúdos doutrinais e/ou poéticos expressados nesta parte fundamental do seu poema, para fazer ver o que têm de poderosamente originais e, em consequência, tratar de determinar o significado do proêmio no conjunto da obra. (shrink)

It is often assumed that analytic philosophy cannot be treated in a Kuhnian way, since what characterizes philosophical practice is not a disciplinary matrix with paradigmatic exemplars of theoretical and empirical problem solving. We propose to challenge this assumption by arguing that at least in some areas of analytic philosophy one can find disciplinary matrices in the Kuhnian sense and, above all, exemplary cases that give rise to a metatheoretical problem-solving program. In particular, we will focus on meta-theoretical structuralism and (...) its notion of T theoricity. We will show that the work of historical-philosophical analysis carried out by Lorenzano (2008) is a paradigmatic example that has been replicated by several subsequent works, extending the range of application of the disciplinary matrix. (shrink)

Es ya un tópico señalar que en todos los tiempos y en todas las culturas han existido drogas y que han ejercido un papel significativo. Así, han tenido funciones lúdicas, integradoras, explotadoras, medicinales, incluso religiosas. Esta constatación no debería deslizarnos a la falacia historicista en la que, a nuestro juicio, caen algunos estudiosos de la cuestión: como siempre �ha sido así�, no merece reproche ético alguno y, por tanto, puede y �debe ser� así. O a un simplón planteamiento individualista, ultraliberal (...) y burgués: �cada uno consume lo que quiere y cómo quiere�. Esa pretendida libertad individual sólo se puede ejercer autónomamente cuando uno es libre frente a la miseria (no lo eran los yonkis marginales de los 80, ni lo son hoy los niños que viven en las cloacas y esnifan cola) y libre también frente al tedio insoportable (tampoco lo son realmente nuestros actuales jóvenes �triple D�, como veremos). En todo caso, en rigor, un análisis del fenómeno de las drogas es absolutamente inseparable de la consideración cultural de la sociedad en que se produce. (shrink)

El artículo analiza los relatos de la visita de las mujeres a la tumba desde las aportaciones de las ciencias sociales, sobre todo el estudio de los ritos de duelo y la lamentación. A su luz el análisis exegético de los textos evangélicos y otros textos extracanónicos parece apoyar la tesis de que las mujeres discípulas tuvieron una parte importante en los inicios y desarrollo del kerigma pascual y de la tradición posterior, así como en su transmisión. Y eso significa (...) un papel fundamental en la formación de la identidad y legitimación comunitaria Su lugar en esa tradición quedó unido a la sepultura porque posiblemente, debido a su papel tradicional en los ritos de duelo, fue allí donde experimentaron la revelación, donde tuvieron la experiencia reveladora de la resurrección en el curso de su actividad anamnética propia de los lamentos. (shrink)

En este libro tratamos de evaluar la veracidad y de determinar el peso real de los contenidos de la doctrina órfica en Platón, a través del examen exhaustivo de los textos antiguos de que disponemos sobre este movimiento religioso, textos que son, además, presentados y traudcidos en un apéndice final. La indagación pone de manifiesto que hay numerosos puntos del orfismo que inspiraron el pensamiento de Platón, pero que los sometió a una profunda modificación para acoplarlos a sus propias ideas.