BackgroundIn this manuscript, we argue that within the context of phase IV, physician-researchers retain their fiduciary obligation to treat the patient-participants.DiscussionWe first clarify why the perspective that research ethics ought to be differentiated from clinical ethics is not applicable in phase IV, and therefore, why therapeutic orientation is most convivial in this phase. Next, assuming that ethics guidelines may be representative of common morality, we show that ethics guidelines see physician-researchers primarily as physicians and only secondarily as researchers. We then (...) elaborate on what a fiduciary obligation is and how some of the obligations are default duties. Lastly, we look at the fiduciary obligation of the physician-researcher in phase IV interventional trials.ConclusionThe fiduciary obligation to treat is not as easily waived as in earlier trials. Assuming the entwinement of research and practice in phase IV, physician-researchers, in collaboration with other researchers, investigators, and research ethics committees, should ensure that in terms of study design, methodology, and research practice, the therapeutic value of the research to the patient-participants is not diminished. (shrink)

BackgroundIn research ethics, the most basic question would always be, “which is an ethical issue, which is not?” Interestingly, depending on which ethics guideline we consult, we may have various answers to this question. Though we already have several international ethics guidelines for biomedical research involving human participants, ironically, we do not have a harmonized document which tells us what these various guidelines say and shows us the areas of consensus. In this manuscript, we attempted to do just that.MethodsWe extracted (...) the imperatives from five internationally-known ethics guidelines and took note where the imperatives came from. In doing so, we gathered data on how many guidelines support a specific imperative.ResultsWe found that there is no consensus on the majority of the imperatives and that in only 8.2 % of the imperatives were there at least moderate consensus. Of the 12 clusters, Informed Consent has the highest level of consensus and Research Collaboration and Regulatory Sanctions have the least.ConclusionThere was a lack of consensus in the majority of imperatives from the five internationally-known ethics guidelines. This may be partly explained by the differences among the guidelines in terms of their levels of specification as well as conceptual/ideological differences. (shrink)

In Philosophical Fragments the pseudonymous author Johannes Climacus explored the question: What is required in order to go beyond Socratic recollection of eternal ideas already possessed by the learner? Written as an afterword to this work, Concluding Unscientific Postscript is on one level a philosophical jest, yet on another it is Climacus's characterization of the subjective thinker's relation to the truth of Christianity. At once ironic, humorous, and polemical, this work takes on the "unscientific" form of a mimical-pathetical-dialectical compilation of (...) ideas. Whereas the movement in the earlier pseudonymous writings is away from the aesthetic, the movement in Postscript is away from speculative thought. Kierkegaard intended Postscript to be his concluding work as an author. The subsequent "second authorship" after The Corsair Affair made Postscript the turning point in the entire authorship. Part One of the text volume examines the truth of Christianity as an objective issue, Part Two the subjective issue of what is involved for the individual in becoming a Christian, and the volume ends with an addendum in which Kierkegaard acknowledges and explains his relation to the pseudonymous authors and their writings. The second volume contains the scholarly apparatus, including a key to references and selected entries from Kierkegaard's journals and papers. (shrink)

Tem-se analisado, recorrentemente, a influência de Homero e de Hesíodo no proêmio do poema de Parmênides. As possíveis influências da poesia órfica tem sido apenas consideradas. Todavia, diversas descobertas de textos órficos aconselham voltar a analisar os vestígios da tradição mistérica, em geral, e órfica, em particular, no poema do filósofo de Eléia, sem minimizar, com isso, as outras influências já postas em relevo. O autor assinalou, em um trabalho anterior, algumas conexões entre Parmênides e os textos órficos; neste artigo, (...) a análise se centra nos pontos de contato com ideias e imagens literárias dos Mistérios que se encontram no proêmio. Não se trata de determinar as crenças do filósofo, senão de situar, no âmbito da tradição, os conteúdos doutrinais e/ou poéticos expressados nesta parte fundamental do seu poema, para fazer ver o que têm de poderosamente originais e, em consequência, tratar de determinar o significado do proêmio no conjunto da obra. (shrink)

In this work we will take up again the contributions of the feminist philosophy of science around androcentrism, with special emphasis on biology and biomedical sciences. We will propose that such contributions can be ordered according to three different senses of androcentrism, and that important tensions appear between these senses. Following the path traced by Longino, contextual critical empiricism, we will defend that the rational reconstruction of theories can help us to specify where patriarchal decision vectors crouch in scientific practice. (...) To this end, we will present an alternative analysis to Longino’s and use it as an input to discuss the idea of type brains in the framework of the neuroendocrinology of behaviour. (shrink)

The paper deals with of one aspect of “The Laws”: the rules proposed on partying, drinking and the type of music and dance presided over by Dionysus. The Athenian tries to combine: a) the need for education to form law-abiding citizens capable of defending the city; b) the need to control the disturbing effects of drinking and debauchery on music and dance; and c) the desire to maintain the Athenian tradition they were proud of: the conciliation of military excellence and (...) the fun produced by drinking, music and dance. (shrink)

Examina a relevância da Lei de Acesso à Informação – LAI na consolidação institucional do Ministério Público Federal - MP no Brasil. Analisa a sua a atuação durante o regime militar e no processo de redemocratização após a Constituição de 1988. Aponta a sua evolução como instituição permanente e essencial à função jurisdicional do Estado, responsável, perante o Judiciário, pela defesa da ordem jurídica e dos interesses indisponíveis da sociedade, assim como seu papel na investigação de fatos nacionais sobre os (...) perpetradores de violações aos direitos humanos. (shrink)

The diffusion of ideas about contemporary terrorism is analyzed using a sociology of science methodology. One of the most common means of creating understandings of a phenomenon is the development and diffusion of ideas that influence the positions adopted by a wide range of actors, including government bureaucrats and decision makers, legislative and corporate bodies, and the public. How did terrorism researchers interact with these actors to construct, maintain, and modify the development and perception of contemporary terrorism? How were the (...) ideas diffused and what impact did they have on policymakers? Did the invisible college of terrorism researchers function as an epistemic community? These questions are analyzed using an integrated research strategy that employs a number of techniques and data sources such as bibliometrics, content analysis, and citation analysis of selected terrorism research publications, biographies, and conferences, and on-line tracing of researchers’ affiliations, participations, and collaborations. (shrink)

Los libros plúmbeos del Sacromonte forman un audaz intento de resistencia intelectual e intervención en el pensamiento cristiano por parte de la comunidad morisca granadina. Tomando elementos tanto de la proliferación pseudoprofética en la España del XVI como de la visión islámica de la historia de las religiones, se crean unos textos que aunque islámicos en su mensaje final, pueden ser aceptables tanto para cristianos como para musulmanes, especialmente a partir de las traducciones realizadas de los textos árabes. Este intento (...) cristalizaría con esa "Verdad del Evangelio" anunciada en el Sacromonte, que se materializa en el Evangelio de Bernabé, cuyas similitudes con los libros plúmbeos son numerosas, y que presenta lo que desde el punto de vista del Islam podría ser un relato de la vida y mensaje de Jesús antes de las alteraciones efectuadas por el cristianismo. (shrink)

The use in psychology of crowdsourcing platforms as a method of data collection has been increasing in popularity because of its relative ease and versatility. Our goal is to adapt the Gratitude Questionnaire–20 Items to the English language by using data collected through a crowdsourcing platform. The G20 is a comprehensive instrument that takes in consideration the different basic processes of gratitude and assesses the construct’s cognitive, evaluative, emotional, and behavioral processes. We test the psychometric properties of the English version (...) of the G20 with a Prolific user sample. We assess the adequacy of the G20 for the crowdsourcing population in its English version. A description of the characteristics of the participants is conducted. Reliability analyses reveal an optimal internal consistency of the adapted scale. The results are discussed from a cross-cultural vision of gratitude. We conclude that the Gratitude Questionnaire–20 Items, adapted to English with an American sample, is a psychometrically strong instrument to measure gratitude using crowdsourcing platforms for data collection and, therefore, a reference and useful tool in future research. (shrink)

O objetivo deste artigo foi investigar a leitura neopragmatista de Richard Rorty (1931-2007) sobre a concepção de subjetividade em Michel Foucault (1926-1984). Rorty ficou conhecido como um celebre filósofo que se opôs à concepção moderna de sujeito, sobretudo, o excesso de antropocentrismo e cientificismo. Quanto ao filósofo francês Michel Foucault, pode-se constatar no terceiro domínio de sua produção teórica, a presença de uma investigação vigorosa sobre a constituição do sujeito. Inicialmente, percebe-se desde seus primeiros escritos, o papel que exerce o (...) poder e a verdade enquanto mecanismos criadores de subjetividade, impondo aos sujeitos modos de ser e de relacionar-se consigo e com os outros. Todavia, a análise sobre a questão da constituição do sujeito se configura de forma mais delimitada nos cursos Subjetividade e Verdade (1981) e A Hermenêutica do Sujeito (1982). Foucault desenvolve uma investigação sobre a subjetividade a partir das noções de ética, filosofia, espiritualidade, sexualidade, arte de viver e cuidado de si, buscando compreender como o sujeito torna-se assujeitado pelo poder e saber, sugerindo novos modos de subjetividade, diferentes daqueles propostos pelo poder. Entretanto, contrariamente ao que propôs Foucault, o filósofo norte-americano neopragmatista Richard Rorty, conhecido por propor uma filosofia edificante, afirma na obra Contingência, ironia e solidariedade (2007) que as ideias do filósofo francês, embora tentem se desvencilhar da concepção moderna de subjetividade, ainda se mantêm atreladas a ela. Assim, pretende-se explorar os argumentos rortyanos que justificam às objeções a Foucault, e com base na análise de textos específicos de ambos os autores, se busca identificar os argumentos usados por Rorty para acusar Foucault de permanecer no quadro teórico da modernidade. (shrink)

Lotman’s contribution to semiotic theory, anthroposemiotics, the study of artistic texts and defining the relationship between language and culture represent some of the most powerful work produced within the Tartu–Moscow School of Semiotics. The importance of translation is one of the central principles that unites all of Lotman’s work. In the following paper, we will consider Lotman’s definition of translatability in the context of (1) the definition of semiospheric internal and external boundaries and the importance of crossing these boundaries, (2) (...) the role of no fewer than two languages as a minimal unit of semiotic meaning-generation, (3) culture text-level generation of collective memory, and (4) the ever-present tension in the communication act. In our concluding section, we will offer an extended model of the communication act, based on the fundamental principles given in Jakobson, Sebeok and Lotman, in order to specify important moments of the translation process. (shrink)

O presente artigo analisa o projeto filosófico de John Dewey (1859-1952) que consta de uma crítica radical à epistemologia tradicional a partir da concepção pragmatista de experiência. O status científico da filosofia, conforme Dewey, não exigirá uma teoria científica passível de prova, mas um programa metafísico construído a partir de lógicas situacionais. O presente artigo apresenta as dimensões históricas e científicas da metafísica empírica de Dewey, argumentando a favor da articulação entre as duas abordagens que configuram o projeto de reconstrução (...) da filosofia. Dewey compreende que a busca dos fundamentos últimos tornou a filosofia prisioneira de uma imagem da mente como construtora de representações - algumas exatas, outras não, mas todas com a pretensão de serem estudadas por meio de métodos puros, não empíricos. Diferentemente dessa tradição que supõe uma ideia de superioridade intelectual do saber, revelado por meio de métodos não empíricos, Dewey argumenta a favor do empírico em filosofia e se coloca contra uma comum concepção da realidade como segura, regular e acabada. Palavras Chave: Experiência. Natureza. Metafísica empírica. Reconstrução filosófica. (shrink)

A methodology is shown to evaluate the quality of the continuous improvement plans in schools of the upper medium type. For this, a rubric validated by expert judgment and Alpha de Crombach was prepared. The results obtained show the distribution of the quality level of the PMC, as well as the most recurring errors during the planning process.