In this article we develop and defend what we call the “Trust View” of promissory obligation, according to which making a promise involves inviting another individual to trust one to do something. In inviting her trust, and having the invitation accepted (or at least not rejected), one incurs an obligation to her not to betray the trust that one has invited. The distinctive wrong involved in breaking a promise is a matter of violating this obligation. We begin by explicating the (...) core notion of “inviting someone to trust one to do something”, suggesting that it involves signaling to the other individual one's recognition of the importance the relevant action has for her, and one’s willingness to license her to have faith or optimism in one's character with regard to the performance of that action. We then turn to a defense of the Trust View, arguing that it has considerable appeal in its own right, that it is distinct from and superior to three similar accounts (T.M. Scanlon's Assurance View, Judith Jarvis Thomson's Reliance View and David Owens' Authority View), and that several objections to it can be answered. (shrink)

This is the third volume to appear in an edition that will be the first complete, critical, and annotated English translation of all of Nietzsche's work. The edition is a new English translation, by various hands, of the celebrated Colli-Montinari edition. The present volume provides for the first time English translations of all of Nietzsche's unpublished notebooks from summer 1872 to the end of 1874. The major works published in this period were the first three Unfashionable Observations: 'David Strauss the (...) Confessor and the Writer,' 'On the Utility and Liability of History for Life,' and 'Schopenhauer as educator.' Translations of the preliminary notes for these pieces are coordinated with the translations of the published texts printed in Volume 2: Unfashionable Observations. These notebooks represent important transitional documents in Nietzsche's intellectual development, marking, among other things, the shift away from philological studies toward unabashed cultural criticism. (shrink)

Überwindet Technik das unheimlich Unbeherrschbare? Oder wird sie uns selbst unheimlich? Zwei scheinbar widersprüchliche Narrative prägen die Geschichte und auch die Theorie der Technik: Das Narrativ der Entzauberung beschreibt, wie eine als fremd und gefährlich erfahrene Natur durch Verwissenschaftlichung und Technisierung gezähmt wurde. Das Narrativ der Verzauberung schildert, wie uns Artefakte und technologische Möglichkeiten unheimlich werden, insbesondere wenn sie sich zu verselbständigen scheinen oder mit „autonomem“ Eigensinn gegenübertreten. In den heutigen Debatten um selbstlernende, ubiquitär verteilte, im Assistenzmodus unsichtbare, dabei opake (...) Techniken schwingt das unheimliche Moment einer „Verselbständigung“ von Technik mit – und trägt im Anschluss an die Mechanisierungs- und Automatisierungsdiskurse des 20. Jahrhunderts zur „Dämonisierung“ der Technik bei. Technik macht Welt einerseits vertraut und nachvollziehbar: Paradigmatisch wird dies in der Idee, dass etwas dann verstanden wird, wenn es technisch rekonstruiert werden kann. Andererseits wird die technische Reproduktion von Welt – oder deren radikale Umgestaltung zu einer entfremdeten – als etwas Verstörendes erlebt. Spätestens, wenn Artefakte zu tun scheinen, „was sie wollen“ oder technische Großsysteme die Lebenswelt nach ihren „Eigenlogiken“ prägen, ist eine schon von Freud benannte Grenze erreicht, an der wir verunsichert werden, ob wir überhaupt noch in der modernen Welt leben. (shrink)

The articles in this volume deal with the main inferential methods that can be applied to different kinds of experimental evidence.

Originally published as separate volumes as Mixed Opinions and Maxims (1879) andThe Wanderer and His Shadow (1880), the two works included here continue the aphoristic style begun in Volume I of Nietzsche's "Book for Free Spirits" and offer a window into the intellectual sources behind his evolution as a philosopher.

The mechanisms invoked to demonstrate how self-deception can occur without intention or awareness imply that self-deceptive beliefs are nevertheless the outcome of inappropriate and often egoistically driven processes. In contrast, models of pragmatic reasoning suggest that self-deception may well be the “reasonable” output of a more generalized, adaptive approach to hypothesis testing.

Introduction, by Willard Huntington Wright.--Thus spake Zarathustra, translated by Thomas Common.--Beyond good and evil, translated by Helen Zimmern.--The genealogy of morals, translated by Horace B. Samuel.--Peoples and countries, translated by J. M. Kennedy.--Ecce homo, translated by Clifton P. Fadiman.--The birth of tragedy from the spirit of music, translated by Clifton P. Fadiman.

Background Sharing anonymized/de-identified clinical trial data and publishing research outcomes in scientific journals, or presenting them at conferences, is key to data-driven scientific exchange. However, when data from scientific publications are linked to other publicly available personal information, the risk of reidentification of trial participants increases, raising privacy concerns. Therefore, we defined a set of criteria allowing us to determine and minimize the risk of data reidentification. We also implemented a review process at Takeda for clinical publications prior to submission (...) for publication in journals or presentation at medical conferences. Methods Abstracts, manuscripts, posters, and oral presentations containing study participant information were reviewed and the potential impact on study participant privacy was assessed. Our focus was on direct and indirect identifiers, such as sex, age or geographical indicators in rare disease studies or studies with small sample size treatment groups. Risk minimization was sought using a generalized presentation of identifier-relevant information and decision-making on data sharing for further research. Additional risk identification was performed based on study participant/personnel parameters present in materials destined for the public domain. The potential for participant/personnel identification was then calculated to facilitate presentation of meaningful but de-identified information. Results The potential for reidentification was calculated using a risk ratio of the exposed versus available individuals, with a value above the threshold of 0.09 deemed an unacceptable level of reidentification risk. We found that in 13% of Takeda clinical trial publications reviewed, either individuals could potentially be reidentified or inappropriate data sharing plans could pose a data privacy risk to study participants. In 1/110 abstracts, 58/275 manuscripts, 5/87 posters and 3/58 presentations, changes were necessary due to data privacy concerns/rules. Despite the implementation of risk-minimization measures prior to release, direct and indirect identifiers were found in 11% and 34% of the analysed documents, respectively. Conclusions Risk minimization using de-identification of clinical trial data presented in scientific publications and controlled data sharing conditions improved privacy protection for study participants. Our results also suggest that additional safeguards should be implemented to ensure that higher data privacy standards are met. (shrink)

First Published in 1999. Routledge is an imprint of Taylor & Francis, an informa company.

In their article “Two Minds, One Patient: Clearing Up Confusion About ‘Ambivalence,’” Moore et al. argue that “different kinds of ‘ambivalence’ may call for different approaches” to resolution in c...

Três poemas de Schelling-Bonaventura. Tradução de “Tier und Pflanze”, “Lied” e “Los der Erde”.

In many ways, grief is thought to be outside the realm of bioethics and clinical ethics, and grieving patients or family members may be passed off to grief counselors or therapists. Yet grief can play a particularly poignant role in the ethical encounter, especially in cases of brain death, where the line between life and death has been blurred. Although brain death is legally and medically recognized as death in the United States and elsewhere, the concept has been contentious since (...) its inception in 1968. Yet in most cases, families are not allowed to reject the determination of brain death. Apart from religious exemptions, families have no recourse to reject this controversial determination of death. This paper explores the role of grief in brain death determinations and argues that bioethics has failed to address the complexity of grief in determinations of brain death. Grief ought to have epistemological weight in brain death determinations because of the contested nature of the diagnosis and the unique ways in which grief informs the situation. Thus, I argue that, in some rare cases, reasonable accommodation policies should be expanded to allow for refusals of brain death determinations based on the emotional and moral force of grief. By drawing on ethnographic accounts of grief in other cultures, I problematize the current procedural and linear understandings of grief in brain death determinations, and I conclude by offering a new way in which to understand the case of Jahi McMath. (shrink)

Elementary textbook introducing several topics from numerical mathematics, with many exercises and solutions. For students and practitioners from engineering and natural sciences.

Keine ausführliche Beschreibung für "Menschliches, Allzumenschliches. Band 1, Nachgelassene Fragmente, 1876 bis Winter 1877-1878" verfügbar.

Des choses divines et de leur revelation est le testament philosophique de son auteur, Friedrich Heinrich Jacobi. La premiere evaluation d'ensemble du postkantisme et des grands systemes idealistes qu'il y propose determine encore l'image que nous pouvons nous faire de la philosophie classique allemande. La querelle qu'elle a declenchee et la reponse outranciere que lui a apportee Schelling, blesse par la critique du naturalisme que developpe la deuxieme partie de l'ouvrage, en font le document le plus precieux dont nous (...) disposions pour interpreter les debats qui, durant les premieres decennies du XIXe siecle, ont mis aux prises la philosophie de la religion et la theologie speculative. La discussion des rapports du realisme et de l'idealisme religieux, de la revelation de la raison et de la doctrine positive que Jacobi developpe d'abord en reponse a Matthias Claudius, puis lors d'un dialogue avec Friedrich Schlegel, non seulement eclaire cette lecture de l'histoire de la philosophie a l'heure de l'avenement du nihilisme, mais permet aussi de comprendre ce que l'auteur entend par ce vrai rationalisme qu'il oppose aux philosophes de son temps. Elle donne ainsi a celui qui fut l'un des peres de l'idealisme allemand en meme temps que son critique le plus acerbe l'occasion de preciser une derniere fois les rapports de la raison et de l'entendement, question qu'avec Kant, il fut l'un des premiers a poser a la pensee moderne. (shrink)