This paper seeks to expand our appreciation of the gene editing tool, clustered regularly interspaced short palindromic repeats‐associated protein 9 (CRISPR‐Cas9), its function, its benefits and risks, and the challenges of regulating its use. I frame CRISPR's emergence and its current use in the context of 150 years of formal exploration of heredity and genetics. I describe CRISPR's structure and explain how it functions as a useful engineering tool. The contemporary international and domestic regulatory environment governing human genetic interventions is (...) reviewed and shown to be increasingly ineffective in its ability to restrain, guide, and optimize the emerging use of CRISPR. Several reasons for this lack of consensus are discussed. In conclusion, I suggest a number of public policy recommendations that might allow us to simultaneously embrace our most important moral values and manage the inevitable power CRISPR will come to have in our lives. (shrink)

Health care institutions, including Roman Catholic institutions, are in a time of crisis. This crisis may provide an important opportunity to reinvigorate Roman Catholic health care. The current health care crisis offers Roman Catholic health care institutions a special opportunity to rethink their fundamental commitments and to plan for the future. The author argues that what Catholic health care institutions must first do is articulate the nature of their identity and their commitments. By a renewed commitment to the praxis of (...) health care on their own distinctive terms, Roman Catholic health care institutions may reestablish a vision of human nature and human service in an increasingly secular society. Health care could then reclaim its place as a powerful setting for the expression of Roman Catholic faith, life and witness. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:THEOLOGY, PRAXIS, AND ETHICS IN THE THOUGHT OF JUAN LUIS SEGUNDO, S.J. JOEL ZIMBELMAN California State University, Chico Chico, California I. Introduction JESUS OF NAZARETH Yesterday and Today is Juan Luis Segundo's most recent contribution in an on-going effort to forge a distinctive post-conciliar catholic theology.1· This five-volume work establishes Segundo as one of the most prolific, methodologically sophisticated, and constructive Catholic theologians of this century. In these volumes (...) he moves beyond the task of reframing fundamental theology in political and social terms that he began in earlier works and undertakes a full elaboration of the theological method that he introduced in The Liberation of Theology.2 Better than any previous work, the recent effort witnesses to the author's range of interests and strengths, 1 Originally published in the Spanish as El hombre de hoy ante Jesus de Nazaret (Madrid: Ediciones Christiandad, 1982): Vol. I. Fe e ideologia; Vol. II/1 and 2 Historia y actualidad: Sinopticos y Pablo; Vol. II/3 El Cristo de los ejercicios espirituales; Vol. II/4 Lineas actuates de interpretacion de Jesus de Nazaret. English translation Jesus of Nazareth Yesterday and Today, tr. John Drury (Maryknoll, N.Y.: Orbis Books) : vol. 1 Faith and Ideologies (1984); vol. 2 The Historical Jesus of the Synoptics (1985); vol. 3 The Humanist Christology of Paul (1986) ; vol. 4 The Christ of the Ignatian Exercises (1987); vol. 5 An Evolutionary Approach to Jesus of Nazareth (1988). 2 The Liberation of Theology, tr. John Drury (Maryknoll, N.Y.: Orbis Books, 1976). For earlier efforts at political and social theology, see A Theology for Artisans of A New Humanity, tr. John Drury (Maryknoll, N.Y.: Orbis Books): vol. 1 The Community Called Church (1973); vol. 2 Grace and the Human Condition (1973) ; vol. 3 Our Idea of God (1973) ; vol. 4 The Sacraments Today (1974); vol. 5 Evolution and Guilt (1974). 233 234 JOEL ZIMBELMAN including theology and philosophy, hermeneutics and critical social theory, linguistic theory, and biblical studies. Continuing analysis and assessment of liberation theory, and Segundo's recent effort in particular, is warranted for at least three reasons. First, Jesus of Nazareth and particularly its first volume, Faith and Ideologies, clarifies Segundo's constructive project. The volume reasserts much that is already familiar to Segundo's past readers : a deconstructive hermeneutic; the elaboration of the concepts of faith and ideology; and an interpretation of the relationship of faith to praxis, efficacy, and liberation. But it also breaks new and creative ground as it begins to construct the foundations of a moral epistemology and teleology, a more fully developed theory of value appropriation, and an anthropology grounded in transcendental-existentialist and process categories. One can only appreciate the scope and implications of Segundo's thought in a critical analysis of this recent work. Second, Segundo's ·effort calls for further discussion because of its inevitable influence on the development of other constructive and critical Christian theologies. The visions of " geotheology,'' "world Catholicism," and a "liberating theology" advanced by Latin and North American Catholics are no longer the preoccupations of a peripheral minority but reflect the aspirations of conservative, moderate, and progressive voices in the Christian church. As part of this constructive task, a growing number of contemporary thinkers are addressing concerns or appropriating categories and constructs developed or elaborated by Segundo.8 His theological breadth and sophistication means 8 For discussions of this shift, see Alfred Hennelly, "Today's New Task: Geotheology,'' America 18 (January 1975): 27-29; and Penny Lernoux, People of God: The Struggle for World Catholicism (New York: Viking/ Penguin, 1989). Those either indebted to or engaged in substantial conversation with Segundo include Matthew Lamb, Solidarity With Victims: Toward a Theology of Social Transformation (New York: Crossroads, 1982) ; Congregation for the Doctrine of the Faith, " Instruction on Christian Freedom and Liberation," Origins: N. C. Documentary Service 15 (17 April 1986): 713-27; Rebecca Chopp, The Praxis of Suffering: An Interpretation of Liberation and Political Theologies (Maryknoll, N.Y.: Orbis Books, 1986) ; Alfred Hennelly, Theology for a Liberating Church: The New Praxis of Freedom (Washington, D.C.: Georgetown University Press, 1989). TltOUGB:T OF JUAN LUlS SEGUNbO, S.J. 235 that... (shrink)

In a recent critique of informed consent, Robert Veatch argues that the practice is in principle unable to attain the goals for which it was developed. We argue that Veatch's focus on the theoretical impossibility of determining patients' best interests is misapplied to the practical discipline of medicine, and that he wrongly assumes that the patient-physician communication fails to provide the knowledge needed to insure the patient's best interests. We further argue that Veatch's suggested alternative, value-based patient-professional pairing, is, on (...) his own terms, impossible to implement. Finally, we reexamine the philosophical and practical justifications for informed consent and conclude that the practice should be retained. (shrink)