Is inheritable genetic modification the new dividing line in gene therapy? The editors of this searching investigation, representing clinical medicine, public health and biomedical ethics, have established a distinguished team of scientists and scholars to address the issues from the perspectives of biological and social science, law and ethics, including an intriguing Foreword from Peter Singer. Their purpose is to consider how society might deal with the ethical concerns raised by inheritable genetic modification, and to re-examine prevailing views about whether (...) these procedures will ever be ethically and socially justifiable. The book also provides background to define the field, and discusses the biological and technological potential for inheritable genetic modification, its limitations, and its connection with gene therapy, cloning, and other reproductive interventions. For scientists, bioethicists, clinicians, counsellors and public commentators, this is an essential contribution to one of the critical debates in current genetics. (shrink)

In this paper we make an argument for limiting veterinary expenditure on companion animals. The argument combines two principles: the obligation to give and the self-consciousness requirement. In line with the former, we ought to give money to organisations helping to alleviate preventable suffering and death in developing countries; the latter states that it is only intrinsically wrong to painlessly kill an individual that is self-conscious. Combined, the two principles inform an argument along the following lines: rather than spending inordinate (...) amounts of money on veterinary care when a companion animal is sick or injured, it is better to give the money to an aid organisation and painlessly kill the animal. (shrink)

(2006). Liberalism, Nihilism and Modernity in the Political Thought of John Gray. Critical Review of International Social and Political Philosophy: Vol. 9, The Political Theory of John Gray, pp. 285-304.

I argue that an identity theorist can successfully resist a Kripkean modal argument by employing what I call a metaconceptual move. Furthermore, by showing how this move fails to apply straightforwardly to Chalmers' argument, I clarify the nature of the threat presented by Chalmers and how it differs from a Kripkean modal argument.

The Vocabulary of a Modern European State is the companion volume to The Concept of a Philosophical Jurisprudence and completes the enterprise of gathering together Oakeshott’s previously scattered essays and reviews. As with all the other volumes in the series it contains an entirely new editorial introduction explaining how the writings it contains find their place in his work as a whole. It covers the years 1952 to 1988, the period during which Oakeshott wrote his definitive work, On Human Conduct. (...) The essay from which the volume takes its title was intended as a companion piece to the third part of the latter work, and is just one of over sixty pieces that it includes. The volume draws together critical responses to works by major philosophers, historians, and political theorists of his own generation such as Bertrand de Jouvenel, Herbert Marcuse, and Michael Polanyi as well as to some major figures of current scholarship such as Quentin Skinner and Roger Scruton. (shrink)

Male violence against women is at shocking levels in South Africa. According to Faul, ‘A woman is killed by an intimate partner every eight hours, a probable underestimate because no perpetrator is identified in 20 percent of killings’, whilst ‘More than 30 percent of girls have been raped by the time they are 18’. Reeva Steenkamp’s killing by her partner, Oscar Pistorius, came ‘the day before she planned to wear black in a “Black Friday” protest against the country’s excruciatingly high (...) number of rapes’. The purpose of this article is to reread a key biblical text regarding male violence against women in order to highlight how Jesus would want us to respond to such violence. The text is John 7:53–8:11. The NRSV: Catholic Edition entitles the story ‘The woman caught in adultery’. However, this title is problematic as it can lead to misleading readings of the text, as I will show, and so I have given it a different title, namely ‘The woman threatened with stoning’. (shrink)

Jeremy Bentham, the philosopher and reformer, was at the height of his fame and influence in the 1820s. The 301 letters in this volume, many of which are previously unpublished, contain correspondence with international leaders such as Simón Bolívar, the 'Liberator', and Bernardino Rivadavia of Buenos Aires, British statesmen such as Robert Peel and Henry Brougham, and leading intellectuals such as John Stuart Mill and Sarah Austin.

Jeremy Bentham, the philosopher and reformer, was at the height of his fame and influence in the 1820s. The 301 letters in this volume, many of which are previously unpublished, contain correspondence with international leaders such as Simn Bolvar, the 'Liberator', and Bernardino Rivadavia of Buenos Aires, British statesmen such as Robert Peel and Henry Brougham, and leading intellectuals such as John Stuart Mill and Sarah Austin.

This twelfth volume of Correspondence contains authoritative and fully annotated texts of all known letters sent both to and from Bentham between July 1824 and June 1828. The 301 letters, most of which have never before been published, have been collected from archives, public and private, in Britain, the United States of America, Switzerland, France, Japan, and elsewhere, as well as from the major collections of Bentham Papers at University College London Library and the British Library.In mid-1824 Bentham was still (...) preoccupied with the Greek struggle for independence against Turkey, though his active involvement waned as he became disenchanted with the behaviour of the deputies sent to London by the Greek National Assembly. His international reputation was reflected in his continuing contact with Simón Bolívar and Bernardino Rivadavia in South America, and with John Quincy Adams, John Neal, Henry Wheaton, and others in the United States, and his forging of new contacts in Guatemala, India, and Egypt. In the autumn of 1825 he visited France, where he stayed with Jean Baptiste Say and La Fayette, and was fêted by the French liberals.Bentham made considerable progress drafting material for his pannomion, or complete code of laws, and in particular for his Constitutional and Procedure Codes, while John Stuart Mill edited the massive Rationale of Judicial Evidence. Bentham became increasingly active in the cause of law reform, and exchanged a series of letters on the subject with Robert Peel, the Home Secretary, and Henry Brougham. He maintained his friendships with John and Sarah Austin, George and Harriet Grote, James and John Stuart Mill, John Bowring, Joseph Hume, Francis Burdett, Francis Place, and Joseph Parkes, re-established contact with the third Marquis of Lansdowne, son of his old friend the first Marquis, and made new acquaintances in James Humphreys, Sutton Sharpe, and Albany Fonblanque. (shrink)

This path-breaking book reconceptualizes our understanding of political tolerance as well as of its foundations.

La enseñanza moral católica afirma que es necesario el consentimiento de los pacientes para autorizar las intervenciones sanitariasque les afectan, pero no especifica las condiciones para obtener dicho consentimiento o evaluar la capacidad de decisión. Aquí se presentan los artículos recogidos en este número que los autores han desarrollado a partir de las presentaciones que hicieron durante un coloquio reciente de la Asociación Internacional de Bioética Católica (IACB) celebrado en Quebec, Canadá. Contribuyen a promover el pensamiento ético sobre la capacidad (...) de toma dedecisiones y el consentimiento. De diversas formas, piden que se respete la dignidad de todos los pacientes y que se promueva su participación tanto como sea posible en la toma de decisiones sobre su salud. Consideran que la toma de decisiones es relacional y abarca una variedad de capacidades. Examinan el papel de los miembros de la familia y de otros partidarios de la toma de decisiones en la promoción de las capacidades de los pacientes, cuya condición de salud mental o discapacidad les impide a menudo cumplir con los estándares clínicos y legales típicos para la capacidad de toma de decisiones. (shrink)

Peter Abelard (1079–1142 ce) was the most wide‐ranging philosopher of the twelfth century. He quickly established himself as a leading teacher of logic in and near Paris shortly after 1100. After his affair with Heloise, and his subsequent castration, Abelard became a monk, but he returned to teaching in the Paris schools until 1140, when his work was condemned by a Church Council at Sens. His logical writings were based around discussion of the “Old Logic”: Porphyry's Isagoge, aristotle'S Categories and (...) On Interpretation and boethius'S textbook on topical inference. They comprise a freestanding Dialectica (“Logic”; probably c.1116), a set of commentaries (known as the Logica [Ingredientibus], c. 1119) and a later (c. 1125) commentary on the Isagoge (Logica Nostrorum Petititoni Sociorum or Glossulae). In a work Abelard called his Theologia, issued in three main versions (between 1120 and c.1134), he attempted a logical analysis of trinitarian relations and explored the philosophical problems surrounding God's claims to omnipotence and omniscience. The Collationes (“Debates,” also known as “Dialogue between a Christian, a Philosopher and a Jew”; probably c.1130) present a rational investigation into the nature of the highest good, in which the Christian and the Philosopher (who seems to be modeled on a philosopher of pagan antiquity) are remarkably in agreement. The unfinished Scito teipsum (“Know thyself,” also known as the “Ethics”; c.1138) analyses moral action. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Crushing Pressures and Radical IdeasJohn Z. Sadler, MD (bio)Back in 2011, I wrote a paper for the Journal of Bioethical Inquiry, an Australian journal, for a special issue dedicated to ethical issues associated with psychiatric genetics research. The editor was particularly excited by the recent findings of the 5-HTT allele in psychiatric illness. I had different ideas about what I wanted to write about, and the editor, Michael Robertson, (...) graciously considered them and ultimately published the paper. At the time I was interested in the colossal investment of National Institutes of Mental Health (NIMH) research dollars in psychiatric genetic research; at the time I was troubled at the lack of on-the-ground clinical implications of this research investment, and figured an Australian journal and referees would be more generous to a critical paper on U.S. funding priorities. I dug into the National Institutes of Health (NIH), NIMH, and National Science Foundation websites and found some crude dollar evidence of respective expenditures for research funding in various disorders and focus areas, and compared these investments to psychiatric genetic research funding commitments. I will not go into details (Sadler, 2011), but the gist was that the psychiatric genetics research enterprise was and had been an extraordinarily expensive enterprise, when other research questions that could be immediately implementable into clinical care improvements remained marginally funded at best. The paper was not read widely and other than a couple of annoyed responses from psychiatric genetic researchers, not much came of it.This concern about funding priorities was one of the reasons why I was pleased to see this paper by Turkheimer and Greer which explores the long term results of the Spit for Science (S4S) initiative, which was launched grandly the same year as my paper’s whisper from down under. I hope this Philosophical Case Conference explores the many dimensions of interest for this paper, which is extraordinarily careful and even handed in its attitude, while at the same time being incisive in its analysis.My focus here is not in the science per se, which is beyond my competence. I’m interested in Turkheimer and Greer’s (T&G) conceptual overview of this research program. More specifically, I focus on T&G’s highlighting of the extraordinary willingness of the S4S authors to interpret prevailingly negative results in the most generous, even misleading, degree possible. I try to provide some possible ways of understanding this kind of research rhetoric exhibited by a cohort of highly respected, very successful scientists.I acknowledge the well-described varieties of interpretive bias that all of us are subject to. First on the list must be confirmation bias, our tendency to interpret situations in terms consistent [End Page 447] with our preconceived notions—in this case, the idea that genetics has something important to do with addictive disorders. Another might be epistemic overconfidence—the tendency to fail at interpretive skepticism in favor of one’s preferred conclusion. Related to this may also be interpretive momentum, the tendency to maintain a conviction about the correctness of one’s expectations and disregard inconsistent findings over the course of a research program—in this case, the multiple S4S studies (O’Sullivan & Schofeld, 2018). However, these kinds of biases tend to “blame” the individual authors’ thinking styles. I opine, though, that other vectors shaping the declaring-success rhetoric are more important.These sources have to do with the state of practice in doing biomedical science research in universities and particularly academic medical centers (AMCs) today. I identify several causal vectors that compel, however subtly, researchers to declare success in the face of failure. I have only picked three, and in no order of importance: 1) funding caps for NIH grants, 2) the overleveraging of university budgets and ballooning dependence on soft money, and 3) the incentivizing of intellectual property development within AMCs.Funding Caps for NIH GrantsIf you are a university or AMC, one way you hold onto your most productive scientists (e.g., grants, publications, discoveries, and status) is by paying them well. Single NIH grants today commonly amount to millions of dollars, and often tens of millions. These bring... (shrink)

Animals, Equality and Democracy examines the structure of animal protection legislation and finds that it is deeply inequitable, with a tendency to favor those animals the community is most likely to see and engage with. Siobhan O'Sullivan argues that these inequities violate fundamental principle of justice and transparency.

This thesis develops and defends epistemic fictionalism, according to which knowledge talk is metaphorical. One of the distinctive features of metaphor is that metaphorical sentences have multiple readings: a literal (or ‘face-value’) reading and at least one metaphorical (or ‘non-face-value’) reading. Typically, speakers who utter metaphorical sentences intend to communicate a content that corresponds to the metaphorical meaning. Epistemic fictionalism posits that, as is standard for metaphors, sentences of the form “S knows that P” admit of at least two different (...) readings: a face-value (literal) reading, and a different non-face-value metaphorical reading. A face-value reading of sentences of the form “S knows that P” is that S is infallible with regards to P, and as such are always (or almost always) false at face-value. However, such sentences are not typically used to communicate their typically false face-value content, but some other, typically true metaphorical content. The thesis applies the methods of function-first epistemology (Craig 1990, Hannon 2019a), taking as a starting point the question of what knowledge talk is used for. I argue that understanding knowledge talk as metaphorical coheres with the function that knowledge talk plays, in spite of all (or most) knowledge attributions being literally false: there are advantages to communicating the non-face-value, metaphorical content. Another key advantage of epistemic fictionalism is that it explains the intuitions surrounding sceptical arguments. On the one hand, sceptical infallibilism is compelling because it is the correct analysis of the face-value content of knowledge attributions. On the other hand, sceptical infallibilism is not threatening to everyday knowledge attributions because it does not threaten the truth of the metaphorical content that knowledge attributions are typically used to express. Overall, the main aim of the thesis is to motivate epistemic fictionalism as a serious contender worthy of further investigation and development. (shrink)

Este trabalho tem como objetivo apresentar e discutir a filosofia da experiência de John Dewey, enfatizando suas concepções sobre experiência, experiência educativa e propósito. Além disso, apresentar e discutir como os projetos de programação desenvolvidos por crianças no Scratch podem ser entendidos como um propósito no contexto de sua filosofia, o que nos levou a relacionar o conceito de propósito construído por Dewey à ideia de projeto pessoal desenvolvida por Papert, no âmbito do construcionismo. Tal relação se torna importante (...) para ampliar as investigações que tratam problemáticas relacionadas ao ensino de programação na educação básica. A fim de exemplificar as possíveis relações, apresentamos um projeto de programação desenvolvido por um aluno do quinto ano do ensino fundamental, reconhecendo nele os pressupostos teóricos da teoria de Dewey discutidos no texto, relacionando-os às ideias de Papert. (shrink)

Name der Zeitschrift: Paragrana Jahrgang: 25 Heft: 2 Seiten: 80-93.

It has been claimed that empirical work in psychology requires the attribution of representational content to perceptual states: that is, the attribution of veridicality conditions to those states. This is a claim that can only be evaluated by the examination of actual empirical research. In this paper I argue that talk of ‘representation’ in at least one area of research in the psychology of perception can be reinterpreted so as to avoid the attribution of veridicality conditions. This area is the (...) study of human capacities to perceive the relative numerosities of collections of objects. (shrink)

This article argues that history played a larger role in the thought of Gottlob Frege than has usually been acknowledged. Frege’s logical writings frequently employed statements about the past as examples that included references to historical persons. Frege also described history as a science and argued that historical propositions could support valid inferences and reliably identify historical persons and events. But Frege’s eternalist theory of reference, designed primarily for formal concepts and objects, struggled to accommodate such propositions. Identifying an objective (...) referent for the subjectivity of historical actors was particularly problematic. The article suggests that Frege’s writings are interesting for the philosopher of history for at least two reasons: first, his work is clarificatory when considering the key features that historical propositions must have to count as objective knowledge, and second, it foreshadowed the issues with historicity that analytical philosophy experienced in the twentieth century. It concludes that the problems Frege raised exposed the need for a new concept of inter-subjectivity to replace his own Platonic foundation for objectivity. (shrink)

This highly readable new collection of thirty pieces by Michael Oakeshott, almost all of which are previously unpublished, covers every decade of his intellectual career, and adds significantly to his contributions to the philosophy of historical understanding and political philosophy, as well as to the philosophy of education and aesthetics. The essays were intended mostly for lectures or seminars, and are consequently in an informal style that will be accessible to new readers as well as to those already well acquainted (...) with Oakeshott’s works.Early pieces include a long essay ‘On the Relations of Philosophy, Poetry, and Reality’, and Oakeshott’s comments on ‘The Cambridge School of Political Science’ through which he himself had passed as an undergraduate. The collection also reproduces a substantial wartime essay ‘On Peace with Germany’. There are two new essays on the philosophy of education, and the essay which gives the work its title, ‘What is History?’, is just one of over half a dozen discussions of the nature of historical knowledge. Oakeshott’s later sceptical, ‘hermeneutic’, thought is also well represented by pieces such as ‘What is Political Theory?’ and ‘The Emergence of the History of Thought.’ Reviews of books by English and European contemporaries such as Butterfield, Hayek, Voegelin, and Arendt also help to place him in context more clearly than before.The book will be indispensable for all Oakeshott’s readers, no matter which area of his thought concerns them most. (shrink)

Through recourse to Gilles Deleuze’s short polemical essay ‘Postscript on Control Societies’ and the accompanying interview (in Negotiations) on ‘Control and Becoming’, this article attempts to map out the conceptual contours of an artistic war machine (Deleuze’s ‘new weapons’) that might be pitched against control and also play a role in the more ethico-political function of the constitution of a people (or, what Deleuze calls subjectification). Along the way a series of other Deleuzian concepts are introduced and outlined – with (...) an eye to their pertinence for art practice and, indeed, for any more general ‘thought’ against control. At stake here is the development of a concept of fictioning – the production of alternative narratives and image-worlds – and also the idea of art practice as a form of myth-science, exemplified by Burroughs’ cut-up method. It is argued that these aesthetic strategies might offer alternative models for a subjectivity that is increasingly standardized and hemmed in by neoliberalism. (shrink)

Background Research shows that undocumented migrants have difficulties in accessing healthcare. Act 2013:407 came into force in 2013 and entitled undocumented migrants to healthcare that cannot be deferred. To date, studies about undocumented migrants’ access to care in Sweden and the impact of Act 2013:407 are sparse. Hence, the aim of this study was to describe professionals’ experiences of access to healthcare for undocumented migrants in Sweden and the impact of Act 2013:407. Methods A qualitative design with semi-structured interviews was (...) employed. Nine interviews were carried out in 2015 with nurses at two NGO healthcare centres for undocumented migrants – and an additional seven interviews in 2022 with staff at an NGO healthcare centre for undocumented migrants and personnel at a regional health and medical care administration. Interpretive description was used for the analyses. Ethical considerations Permission to carry out the study was obtained from managers at the participating NGOs and the regional health and medical care administration. Participants received verbal and written information about the study, and informed consent was obtained from all participants. Findings Six categories emerged from the analysis: Changes since the Act was introduced, General problems with healthcare access, Care for undocumented migrants – politics and social economy, Lack of knowledge, ‘Healthcare that cannot be deferred’ and Being an undocumented migrant. Conclusion Undocumented migrants’ social needs are as great as their needs for healthcare. Healthcare staff are burdened with healthcare cost considerations which affect their judgement of care provision and prioritization. Healthcare staff attitudes towards undocumented migrants affect their access to healthcare. Undocumented migrants in need of healthcare are especially vulnerable due to their legal status, being ill and the fear of being reported and deported. To assure undocumented migrants’ access to healthcare and maintain healthcare ethics, the only possible solution is to provide healthcare based on needs. (shrink)

In a series of philosophical discussions and artistic case studies, this volume develops a materialist and immanent approach to modern and contemporary art. The argument is made for a return to aesthetics--an aesthetics of affect--and for the theorization of art as an expanded and complex practice. Staging a series of encounters between specific Deleuzian concepts--the virtual, the minor, the fold, etc.--and the work of artists that position their work outside of the gallery or "outside" of representation--Simon O'Sullivan takes Deleuze's (...) thought into other milieus, allowing these "possible worlds" to work back on philosophy. (shrink)

The question of how realism and metanarratives are related in the philosophy of history does not seem to have been widely discussed. Whereas there are distinct philosophical and political senses of ‘realism’, contrasting with ‘idealism’ and ‘utopianism’ respectively, ‘metanarrative’ has a singular meaning based on Jean-François Lyotard’s sceptical definition of postmodernism as “incredulity towards metanarratives”. Lyotard defined metanarratives as philosophies of history that serve some legitimatory function, but claimed that their importance was waning. From this point of view, postmodernism can (...) be described as a species of philosophical ‘realism’. But the appearance of Francis Fukuyama’s ‘end of history’ thesis, which explicitly presented itself as a neo-Hegelian critique of political realism, suggested that Lyotard had underestimated the enduring power of metanarrative insofar as it served the interests of the American liberal-democratic capitalist order. For Jacques Derrida, Fukuyama’s work thus underlined the importance of breaking with what he called ‘onto-theological’ visions of history, although Derrida himself could be seen as authoring a metanarrative in the service of European social democracy. But if so, Derrida’s approach to metanarratives was very different in kind to contemporary religious and nationalistic versions. One way to resolve the difficulty is to make a distinction between modern ‘utopian’ and postmodern ‘realist’ versions of metanarratives. (shrink)

The concept of the public realm is the most fundamental of all political concepts because it is only the shared relationship it constitutes between rulers and ruled that makes government more than mere domination. It is therefore not surprising that the question of how the public realm is to be defined has been a central concern of political thinkers from Plato to more recent philosophers like Hannah Arendt. Although the answers they have given have of course varied greatly, what is (...) relevant in the present context is simply the assumption, for well over two thousand years, that there could be an answer. What is novel today, by contrast, is the increasing realization that political theory cannot in principle provide philosophical guidance of any kind about how the public realm can be finally and definitively identified, in a way which would clearly distinguish it from the private realm and thereby enable an incontestable limit to be set to the proper scope of politics and of state action. The present essay considers how some leading contemporary political thinkers have responded to this situation. (shrink)

There is an apparent tension in William Blake’s attitude toward the visual. Blake denies the value of sense perception, and of perceptible natural objects, as sources of genuine insight. And he is dismissive of “natural religion” on the grounds that natural objects as present to the senses are insufficient to ground religious experience.Blake’s own spiritual experiences are, however, typically described in intensely visual terms. As a child of eight, he saw “a tree filled with angels” on the common at Peckham (...) Rye in south London, and throughout his life reported “visions” as a source of insight. The narrative of “The Marriage of Heaven and Hell” is largely composed of.. (shrink)