This paper discusses the chemistry manuscript collection in an institution that does not readily come to mind when searching for unpublished matter on the history of chemistry, the National Library of Medicine in Bethesda, Maryland. This collection includes personal papers of some twentieth-century American chemists and biochemists, lecture notes of British and American chemistry courses of the eighteenth, nineteenth, and twentieth centuries from a variety of institutional settings, and extended oral histories of some major figures in the history of modern (...) chemistry and biochemistry. Among those represented in this collection are Joseph Black, Louis Pasteur, George B. Wood, Donald D. Van Slyke, and Albert Szent-Györgyi. In addition to illustrating the type of resources available, this paper also suggests some specific ways in which the collection can contribute to research in the history of chemistry. (shrink)