The significance of consciousness in modern science is discussed by leading authorities from a variety of disciplines. Presenting a wide-ranging survey of current thinking on this important topic, the contributors address such issues as the status of different aspects of consciousness; the criteria for using the concept of consciousness and identifying instances of it; the basis of consciousness in functional brain organization; the relationship between different levels of theoretical discourse; and the functions of consciousness.

In several accounts of what models are and how they function a specific view dominates. This view contains the following characteristics. First, there is a clear-cut distinction between theories, models and data and secondly, empirical assessment takes place after the model is built. This view in which discovery and justification are disconnected is not in accordance with several practices of mathematical business-cycle model building. What these practices show is that models have to meet implicit criteria of adequacy, such as satisfying (...) theoretical, mathematical and statistical requirements, and be useful for policy. In order to be adequate, models have to integrate enough items to satisfy such criteria. These items include besides theoretical notions, policy views, mathematisations of the cycle and metaphors also empirical data and facts. So, the main thesis of this chapter is that the context of discovery is the successful integration of those items that satisfy the criteria of adequacy. Because certain items are empirical data and facts, justification can be built-in. (shrink)

I present a reconstruction of F.H.C. Crick's two 1957 hypotheses "Sequence Hypothesis" and "Central Dogma" in terms of a contemporary philosophical theory of causation. Analyzing in particular the experimental evidence that Crick cited, I argue that these hypotheses can be understood as claims about the actual difference-making cause in protein synthesis. As these hypotheses are only true if restricted to certain nucleic acids in certain organisms, I then examine the concept of causal specificity and its potential to counter claims about (...) causal parity of DNA and other cellular components. I first show that causal specificity is a special kind of invariance under interventions, namely invariance of generalizations that range over finite sets of discrete variables. Then, I show that this notion allows the articulation of a middle ground in the debate over causal parity. (shrink)

Offers a fascinating snapshot of magic throughout various cultures as well as deep sociological and religious insights still very much relevant today.

BackgroundFunctional changes after spinal cord injury are related to changes in cortical plasticity. These changes can be measured with electroencephalography and has potential to be used as a clinical biomarker.MethodIn this longitudinal study participants underwent a total of 30 sessions of robotic-assisted gait training over a course of 6 weeks. The duration of each session was 30 min. Resting state EEG was recorded before and after 30-session rehabilitation therapy. To measure gait, we used the Walking Index for Spinal Cord Injury (...) Scale, 10-Meter- Walking Test, Timed-Up-and-Go, and 6-Min-Walking Test. Balance was measured using Berg Balance Scale.ResultsFifteen participants with incomplete SCI who had AIS C or D injuries based on American Spinal Cord Injury Association Impairment Scale classification were included in this study. Mean age was 35.7 years and the mean time since injury was 17.08 months. All participants showed clinical improvement with the rehabilitation program. EEG data revealed that high beta EEG activity in the central area had a negative correlation with gait and balance measured at baseline, in a way that greater high beta EEG power was related to worse clinical function at baseline. Moreover, improvement in gait and balance had negative correlations with the change in alpha/theta ratio in the parietal area.ConclusionIn SCI, functional impairment and subsequent improvement following rehabilitation therapy with RAGT correlated with the change in cortical activity measured by EEG. Our results suggest that EEG alpha/theta ratio may be a potential surrogate marker of functional improvement during rehabilitation. Future studies are necessary to improve and validate these findings as a neurophysiological biomarker for SCI rehabilitation. (shrink)

Δύο ἐπιγραφικά εὑρήματα πού δημοσιεύτηκαν πρόσφατα ἴσως μᾶς ἐπιτρέψουν νά προσδιορίσουμε σέ δύο σημεῖα τό ὁδοιπορικό πού ἀκολούθησε ὁ Παυσανίας στό Ἄργός. Τό πολιτικό κέντρο τῆς πόλης ἦταν ἐγκαταστημένο στους πρόποδες τῆς Λάρισας, κατά μῆκος του δρόμου ἀπό τήν Κόρινθο στήν Τεγέα· στό σημεῖο αὐτό συγκλίνουν οἱ δρόμοι πού ὁδηγοῦν στήν Τίρυνθα καί στήν Ἐπίδαυρο ἀφ' ἑνός, στό Ήραῖο καί στό βορειοανατολικό τμῆμα τῆς 'Αργολίδας ἀφ' ἑτέρου. Φαίνεται πώς θά πρέπει νά γυρέψουμε τήν πύλη τῆς Εἰλιθυίας ἀπό ὅπου ἔφτασε κανείς (...) στό Ήραῖο κάπου πάνω στον ἄξονα τῆς σημερινῆς ὁδοῦ Θεάτρου καί λίγο βορεινότερα. Μιά ἐπιγραφή πού θά μποροῦσε νά προέρχεται ἀπό τό ἱερό τοῦ Διονύσου καί βρέθηκε κοντά στήν ἐκκλησία τοῦ Ἁγίου Πέτρου φαίνεται νά βεβαιώνει τήν ὑπόθεση τοῦ Boethius ὅτι ἡ Κοίλη πρέπει νά ἀναζητηθεῖ σ' αὐτόν τόν τομέα. (shrink)

Résumé Cet article se propose d’examiner comment la notion de « culture de guerre », avancée par certains historiens pour qualifier l’engagement des intellectuels français dans l’Union sacrée contre l’Allemagne dès 1914, se décline dans le cas de Durkheim. À travers l’exemple de son texte de propagande le plus connu : L’Allemagne au-dessus de tout, on se propose de débusquer les arguments sociologiques plus ou moins implicites qu’il mobilise pour dénoncer la « mentalité allemande ». Il en résulte qu’au regard (...) de sa vision de l’évolution des sociétés, la conception du rôle de l’État défendue par l’Allemagne en guerre doit être comprise comme une régression, un « retour vers le primitif », donc comme une énigme sociologique impensée et impensable dans la logique rationaliste qui était la sienne. (shrink)

Kant stresses the regulative status of teleological attributions, but sometimes he seems to treat teleology as a constitutive condition for biology. To clarify this issue, the concept of natural purpose and its role for biology are examined. I suggest that the concept serves an identificatory function: it singles out objects as natural purposes, whereby the special science of biology is constituted. This relative constitutivity of teleology is explicated by means of a distinction of levels: on the object level of biological (...) science, teleology is taken as constitutive, though it is merely regulative on the philosophical meta level. This distinction also concerns the place of Aristotelian teleology in Kant: on the object level, the Aristotelian view is accepted, whereas on the meta level, as agnostic stance is taken concerning teleology. (edited). (shrink)

I examine different arguments that could be used to establish indeterminism of neurological processes. Even though scenarios where single events at the molecular level make the difference in the outcome of such processes are realistic, this falls short of establishing indeterminism, because it is not clear that these molecular events are subject to quantum mechanical uncertainty. Furthermore, attempts to argue for indeterminism autonomously (i.e., independently of quantum mechanics) fail, because both deterministic and indeterministic models can account for the empirically observed (...) behavior of ion channels. (shrink)

The American Journal of Bioethics, Volume 12, Issue 2, Page 16-17, February 2012.

Propose une étude sur une période particulière de l'histoire du philosophe, celle de sa compromission avec le nazisme en 1933.

Le 'Journal métaphysique', qui, primitivement, n'était pas destiné à la publication, est constitué par un ensemble de notes philosophiques rédigées au jour le jour. L'évidente différence de style entre les deux parties tient au fait que sous la pression de la guerre la pensée de l'auteur s'est tournée de plus en plus résolument vers le concret, vers l'existentiel, qui a trouvé dans le Journal métaphysique une des premières expressions qu'il ait revêtues en France. Il ne faut d'ailleurs pas parler de (...) l'existentialisme, mais une thématique de l'existence considérée dans sa spécificité tend à s'y constituer par une réflexion qui se concentre de plus en plus sur le corps propre (par opposition au corps-objet ou instrument), sur la sensation traitée non plus comme message mais comme façon d'être au monde, sur la mémoire, sur la volonté, etc. Des phénomènes métaphysiques tels que la télépathie, la lecture de pensées, etc. sont considérés avec une attention particulière et l'auteur va jusqu'à se demander s'il ne conviendrait pas d'inverser la relation communément pré-supposée entre le psychologique et le métapsychique et si la clef des phénomènes dits normaux ne devrait pas être cherchée dans le supra-normal. (shrink)

Generally, simulations are carried out to answer specific questions. The assessment of the reliability of an answer depends on the kind of question investigated. The answer to a 'why' question is an explanation. The premises of an explanation have to include invariant relationships, and thus the reliability of such answer depends on whether the domain of invariance of the relevant relationships covers the domain of the question. The answer to a 'how much' question is a measurement. A measurement is reliable (...) when it is an output of a calibrated measuring instrument. (shrink)

There has been increased interest in the potential of maternal immunisation to protect maternal, fetal, and infant health. Maternal tetanus vaccination is part of routine antenatal care and immunisation campaigns in many countries, and it has played an important part in the reduction of maternal and neonatal tetanus. Additional vaccines that have been recommended for routine maternal immunisation include those for influenza and pertussis, and other vaccines are being developed. Maternal immunisation is controversial since regulators, professionals, and the public are (...) often reluctant to accept pharmaceutical interventions during pregnancy. So far, little attention has been given to the ethics of vaccination during pregnancy. In this Personal View we argue that maternal immunisation should be offered in response to concrete, severe risks of disease for mother and child, and we explain how this requirement of serious risk can be used to guide ethical decision-making about maternal immunisation. (shrink)

This paper addresses whether we have transparent accurate access to our own conscious experience. It first sketches the origin and social history of this issue in the seventeenth century, when the trust one can have in self- knowledge was disputed in the religious, social and scientific domains. It then reviews evidence that our conscious experience is disunified in several ways and has two levels, can be opaque to us, and contains much that is non-explicit; and that attending to one's experience (...) not only affects and changes it, but may also bring about specific content and phenomenal experience. Quite apart from trusting other people's introspective reports, we cannot trust ourselves even in knowing our own consciousness. Finally, several ways of coping with the problems produced by these characteristics are suggested. (shrink)

, Uppsala, Almqvist & Wiksell International, 1991; 158 pp., price not indicated, ISBN 91-554-2807-X.