Studies by Gardiner and colleagues connecting musical pitch and arithmetic learning support Rips et al.'s proposal that natural number concepts are constructed on a base of innate abilities. Our evidence suggests that innate ability concerning sequence ( or BSC) is fundamental. Mathematical engagement relating number to BSC does not develop automatically, but, rather, should be encouraged through teaching.

Emotion evaluations are assumed to play a crucial role in the emotion regulation process. We tested a postulate from our framework of emotion dysregulation (Nowak, U., Wittkamp, M. F., Clamor, A., & Lincoln, T. M. [2021]. Using the Ball-in-Bowl metaphor to outline an integrative framework for understanding dysregulated emotion. Frontiers in Psychiatry, 12, 118), namely that the extent to which individuals evaluate an emotion as harmful and their personal resources to modify and accept/tolerate the emotion as sufficient predict the subsequent (...) use of regulation strategies. Participants (n = 118) from a community sample took part in an experience-sampling assessment over 7 days including 10 daily paired measurements. The first measured momentary affective valence and arousal along with harmfulness evaluations and evaluations of personal resources to modify and accept/tolerate an emotion. The second followed three minutes later and measured emotion regulation strategies. The more harmful individuals evaluated an emotion, the more likely they were to use an emotion regulation strategy. The more harmful individuals evaluated an emotion, and the less sufficient they evaluated their personal resources to accept/tolerate an emotion, the more likely they were to use a maladaptive emotion regulation strategy. We conclude that emotions that people evaluate as harmful or difficult to accept are most likely to be regulated in a maladaptive manner. This implies that modifying beliefs about emotions could represent a promising treatment approach. (shrink)

In the target article, Juslin & Vll (J&V) contend that neural mechanisms not unique to music are critical to its capability to convey emotion. The work reviewed here provides a broader context for this proposal. Human abilities to signal emotion through sound could have been essential to human evolution, and may have contributed vital foundations for music. Future learning experiments are needed to further clarify engagement underlying musical and broader emotional signaling.

By fostering bonding, music illustrates marvelously its ability to induce emotional experience. But, music can induce emotion more generally as well. To help explain how music fosters bonding and induces other emotions, I propose that music derives this power from the evolution of what I term “gestural messaging.”.

Today, human pluripotent stem cell technologies find widespread application across biomedical research, as models for early human development, as platforms for functional human genomics, as tools for the study of disease, drug screening and toxicology, and as a renewable source of cellular therapeutics for a range of intractable diseases. The foundations of this human pluripotent stem cell revolution rest on advances in a wide range of disciplines, including cancer biology, assisted reproduction, cell culture and organoid technology, somatic cell nuclear transfer, (...) primate embryology, single‐cell biology, and gene editing. This review surveys the slow emergence of the study of human pluripotency and the exponential growth of the field during the past several decades. (shrink)

“Every surgeon carries within himself a small cemetery where from time to time he goes to pray—a place of bitterness and regret, where he must look for an explanation of his failures” René Leriche,...

Biology is the most extensive field in the Corpus Aristotelicum. In his fundamental work De anima, Aristotle tries to fix the borders of this life science. The term ψυχή has a twofold explanatory status. On the one hand, ψυχή is understood as a principle of all living beings. On the other hand, it is understood as a cause of the fact that all living beings are alive. The paper is divided into three sections. The first part shows why Aristotle discusses (...) these issues in a work entitled Περὶ ψυχῆς. Since Pythagoras and Heraclitus, ψυχή was understood as a life principle: Pythagoras believed that men, animals and plants share the same nature: they are all ἔμψυχα and they are homogenous qua ψυχή. The second part of this article deals with Aristotle’s definition of the soul in DA II: ψυχή is the principle of all living things. This establishes the external criteria to divide living and non-living beings and the internal criteria to divide living beings. The third part of this paper is concerned with the methodological consequences of this definition: the life functions are the central explanandum in Aristotle’s biology. De anima II defines such various life-functions as nourishment, sense-perception and locomotion. These capacities contour the main fields of the philosopher’s biological investigation. For Aristotle, the faculty of reproduction is a subtype of nourishment. Reproduction is the most important and most natural function of all living beings. Genetics is, therefore, the most important field in Aristotle’s biology. (shrink)

In no field of knowledge did Aristotle leave more writings than in biol­ogy. He conducted research for longer and more intensively in zoology than in any other field. In these writings he mentions a good 550 animal and 60 plant species. While this includes the internal anatomy of around 110 animals, he dissected 60 species himself. The present contribution deals with the epistemic motifs and the meaning of Aristotelian biology in the context of his scientific curriculum. It is thus demonstrated (...) that in De anima Aristotle’s actual explanations are preceded by an investi­gation of the principles, which aims to differentiate living objects from inanimate ones, and to develop a method of explanation based on the species-specific vital functions of living beings. This article provides an overview of the four main disciplines of Aristotelian biology: compara­tive anatomy, physiology, genetics and behavioral research. The text offers tabular overviews of the animals and plants dealt with by Aristotle. (shrink)

The core thesis of the paper is that the constitution of biological science begins with a conceptual innovation with far-reaching consequences with effect up to the present: by conceiving the parts of living beings as organs (that is, as tools), Aristotle laid the foundation stone for a functional explanation of animate nature. Comparative anatomy is thus transformed from a merely descriptive to an explanatory theory. The point of the discussion is above all that a functional explanation must not be confused (...) with the sort of teleology according to which the function of an organ is understood as the cause of its existence. The first section outlines the theoretical motives that Aristotle adduces in arguing for biology (against contemporary contempt for biological research). The second step addresses the significance of the parts of animals in Aristotle's larger collection of zoological material, the Historia animalium . The third section demonstrates how in the major explanatory work De partibus animalium the term organon takes on the status of a key methodological concept. Finally, the fourth section discusses the significance of the Aristotelian determination of the organic with respect to current discourses in natural science. (shrink)

William James catalogued an amazing diversity of religious experiences. Yet even the pluralistic James was able to find a nucleus, consisting of an uneasiness and its solution, ‘1. The uneasiness, reduced to its simplest terms, is a sense that there is something wrong about us as we naturally stand. 2. The solution is a sense that we are saved from the wrongness by making proper connection with the higher powers.’ But by stressing the moral factor, James seems to exclude those (...) who stress rather the sense of mystery stemming from man's theoretical limitations. Einstein, for example, writes: ‘The most beautiful thing we can experience is the mysterious side of life. It is the deep feeling which is at the cradle of all true art and science. In this sense, and only in this sense, I count myself amongst the most deeply religious people.’ For Einstein as for Pascal : ‘The last proceeding of reason is to recognise that there is an infinity of things which are beyond it.’ Thus I propose the following revision of James' conception of the nucleus of the religious experience: uneasy awareness of the limitations of man's moral or theoretical powers, especially when reality is restricted to sense data and natural objects; awe-full awareness of a further reality—beyond or behind or within; conviction that participation with this further reality is of supreme importance. (shrink)

The ninth and last poem in Book 4 of the Silvae is an amusing hendecasyllabic piece in which Statius, addressing Plotius Grypus, reproves him for having sent him for the Saturnalia a tatty, second-hand copy of a boring book in return for the fine, expensive, new volume which was Statius' present to him. The poem includes a long list of humble and/or poor-quality items, any of which, it is suggested, would have been more acceptable than Grypus' gift. Included in the (...) list are eggs. (shrink)

El artículo enfoca los problemas de convivencia en las ciudades latinoamericanas, marcadas por procesos de urbanización sin articulación, regidos por lógicas de poder y caracterizados por la falta de equilibrio y equidad. Se exploran las posibilidades de pasar de territorios de supervivencia, con relaciones sociales de dominio y violencia, a espacios de comunicación y a lugares de sentido, a través de prácticas, políticas y estrategias de convivencia. The article focuses on the problems of living in Latin American cities, marked by (...) urbanization processes without articulation, governed by logics of power and characterized by a lack of balance and fairness. It explores the possibilities to move from territories of survival, with social relationships of domination and violence, to communicative spaces and places of meaning through practices, policies and strategies of coexistence. (shrink)

The abbey of Conques and its dominant church dedicated to St Foy are today one of the most prominent examples of the harmonic relationship between medieval sacred architecture and nature. This article considers the medieval landscape of Conques from an environmental-historical perspective by analyzing early medieval writings about the abbey. It focuses on early descriptions, which often contain literary, hagiographical topoi depicting ideal, symbolic, or imagined landscapes - sometimes, however, also partially reflecting reality. These descriptions serve, with caution, to investigate (...) the local environment, its transformation, and its effect on the early history of the monastery. In addition, the article delves into the eleventh-century Liber miraculorum sanctae Fidis to investigate strategies that the monastic community used to control St Foy’s estates not only close to the abbey but also in the wider region. Analysis reveals the environment conditions, their impact on the history, and ways in which the monastic community sacralized the landscape through real processions and miracle stories to control it. (shrink)

Much was accomplished in the last decade in understanding how the adaptive immune system evolved to combat pathogens. Essential features of antigen presentation and T lymphocyte recognition were decipherd, setting the stage for further studies that elucidated basic elements of lymphocyte differentiation (including positive and negative selection during lymphocyte ontogeny) and the major interactions that occur among cells in secondary lymphoid organs in an ongoing immune response. The major challenges of today are found in the burgeoning fields of programmed cells (...) death, enzymology of recombination and somatic mutation, development of memory, and the recognition of pathogens by unconventional lymphocytes. (shrink)

Determinism which denies freedom of action is a common philosophical view. Is the action of such determinists incompatible with Kant’s claim that a rationally willed being “cannot act otherwise than under the idea of freedom” [G 4, 448]? In my paper, I examine Kant’s argument for this claim at the beginning of the Third Section of the Groundwork and argue that it amounts to the assertion that one cannot act while being aware of being guided by invalid principles. Belief in (...) determinism does not necessarily amount to such awareness. A structurally similar argument based on the contrast between deliberation and prediction is examined and similarly found wanting. (shrink)

What is the relation between reasoning and self-knowledge? According to Shoemaker, a certain kind of reasoning requires self-knowledge: we cannot rationally revise our beliefs without knowing that we have them, in part because we cannot see that there is a problem with an inconsistent set of propositions unless we are aware of believing them. In this paper, I argue that this view is mistaken. A second account, versions of which can be found in Shoemaker and Byrne, claims that we can (...) reason our way from belief about the world to self-knowledge about such belief. While Shoemaker’s “zany argument” fails to show how such reasoning can issue in self-knowledge, Byrne’s account, which centres on the epistemic rule “If p, believe that you believe that p”, is more successful. Two interesting objections are that the epistemic rule embodies a mad inference and that it makes us form first-order beliefs, rather than revealing them. I sketch responses to both objections. ¿Qué relación existe entre el razonamiento y el autoconocimiento? Según Shoemaker, cierto tipo de razonamiento depende de un autoconocimiento: no podemos revisar nuestras creencias racionalmente sin saber que las tenemos, en parte porque no podemos ver que la inconsistencia de un conjunto de proposiciones constituye un problema a menos que estemos conscientes de creerlas. En el presente artículo argumento que esta propuesta es errónea. Una segunda posición, versiones de la cual se pueden encontrar en Shoemaker y Byrne proclama que es posible razonar desde creencias sobre el mundo hacia un autoconocimiento sobre tales creencias. Mientras el zany argument de Shoemaker no logra mostrar cómo tal razonamiento puede resultar en un autoconocimiento, la teoría de Byrne, que se centra en la regla epistémica “Si p, cree que crees que p” tiene más éxito. Dos objeciones interesantes son que la regla epistémica incorpora una inferencia insana y que nos hace formar creencias de primer orden, en lugar de revelarlas. Esbozo respuestas a ambas objeciones. (shrink)