The relationship between ethics and science has been discussed within the framework of continuity versus discontinuity theories, each of which can take several forms. Continuity theorists claim that ethics is a science or at least that it has deep similarities with the modus operandi of science. Discontinuity theorists reject such equivalency, while at the same time many of them claim that ethics does deal with objective truths and universalizable statements, just not in the same sense as science does. I propose (...) here a third view of quasi-continuity (or, equivalently, quasi-discontinuity) that integrates ethics and science as equal partners toward the uncovering of new knowledge. In this third way, a program envisioned by William James but made practicable only by contemporary scientific advancement, science can and must inform ethics at a deep level, and ethical theory— while going beyond science—cannot do without it. In particular, I identify four areas of ethics-science collaboration: neurobiological research into the basis of moral judgment, comparative anthropol- ogy, comparative evolutionary biology of primates, and game-theo- retical modeling. I provide examples within each of these fields to show how they link to ethical theories (including prescriptive work) and questions. The essay concludes with a brief discussion of the light that a scientifically informed ethics can shed on some classical problems in moral theory, such as the relationships between rational- ity and selfishness, egoism and altruism, as well as the concept of social contract. A joint research program involving both philosophers and scientists is called for if we wish to move ethical theory into the twenty-first century. (shrink)

A conflict of interest is a situation in which a person has competing loyalties or interests that make it difficult to fulfil his or her duties impartially. Conflict of interest is not categorically improper in itself but requires proper management. A SCOPUS literature search was performed for publications on the efficacy/safety of Phospho-Di-Esterase Inhibitors for treating erectile dysfunction. A categorization tool was used to review and classify the publications as supportive/not-supportive for the discussed active ingredient and reporting or not reporting (...) a COI for that specific drug or for the remaining PDEIs. Multivariable binary logistic regression was performed. In the 419 selected records the prevalence of supportive opinions was higher when a COI for the index label was declared. The CoOpCaT showed good internal consistency, discriminative validity and intra/inter-rater agreement. The strongest predictor for a supportive opinion was the total number of financial COIs for the index label. A mild protective effect of the total number of financial COIs for any competitor label was noted. Financial COIs have frequently been associated with bias, and the measures currently adopted to restrain it lack effectiveness. Some evidence for monitoring and/or compensating this bias is reported here, but the ultimate solution remains distant. (shrink)

: Jerry Fodor and Zenon Pylyshyn have proposed a purely referential-causal semantics, a semantics without meanings. Adopting Pylyshyn’s previous treatment of the fact that we can perceive and track something before we have any idea of what that is, these authors claim that such causal relations to external entities allow us to word-label them and thereby build an entire lexicon with specific referents. I disagree and explain why I do so. The kind of semantics that I prefer is radically opposite: (...) the one proposed by Noam Chomsky and Paul Pietroski. This is an internalist semantics that only has meanings, reference being indirect, often indefinite, sometimes problematic. Chomsky insists that the only posit that is tenable is the internal structure of the speaker-hearer, a complex, abstractly characterizable, computational-derivational apparatus, optimal if left alone, that interfaces with other cognitive apparatuses: the articulatory-perceptual one and the conceptual-intentional one, satisfying the constraints that they impose. I show that the semantics proposed by Fodor and Pylyshyn is especially problematic when inexistent entities, possible entities, fictional characters and objects in the remote past are examined. It is, however, problematic even when dealing with more ordinary concepts. On the contrary, an internalist semantics avoids all these problems. Keywords: Internalist Semantics; Theory of Meaning and Reference; Jerry A. Fodor; Noam Chomsky; Paul Pietroski Menti con significati Riassunto: Jerry Fodor e Zenon Pylyshyn hanno proposto una semantica interamente causale-referenziale, una semantica priva di qualsiasi nozione di significato. Adottando la precedente trattazione di Pylyshyn di come è possibile percepire e inseguire oggetti prima di avere alcuna idea di cosa essi siano, questi autori pretendono che queste interazioni causali con enti esterni bastano a etichettarli con dei termini lessicali, costruendo un intero lessico con referenti specifici, senza la componente del significato. Io dissento e spiego perché. Il tipo di semantica che adotto è diametralmente opposto, una semantica che ha solo significati, per la quale i referenti esterni sono indiretti, spesso non definiti, talvolta problematici. Noam Chomsky e Paul Pietroski hanno perfezionato questa semantica puramente internalista, insistendo che l’unico attributo sostenibile è la struttura mentale interna al locutore, una struttura complessa, caratterizzabile solo a un livello di astrazione adeguato, atta a soddisfare i vincoli imposti dai sistemi cognitivi con i quali interagisce: quello articolatorio-percettivo e quello concettuale-intenzionale. Mostro che la semantica proposta da Fodor e Pylyshyn si scontra con problemi insolubili quando tratta enti inesistenti, enti possibili, invenzioni letterarie e oggetti appartenenti a un passato remoto. In effetti, si scontra con problemi insolubili anche quando tratta oggetti e proprietà ordinari. Una semantica interamente internalista non incontra nessuno di questi problemi. Parole chiave: Semantica internalista; Teoria del significato e del riferimento; Jerry A. Fodor; Noam Chomsky; Paul Pietroski. (shrink)

"The last remnant of physical objectivity of space-time" is disclosed, beyond the Leibniz equivalence, in the case of a continuous family of spatially non-compact models of general relativity. The physical individuation of point-events is furnished by the intrinsic degrees of freedom of the gravitational field, (viz, the "Dirac observables") that represent - as it were - the "ontic" part of the metric field. The physical role of the "epistemic" part (viz. the "gauge" variables) is likewise clarified. At the end, a (...) peculiar four-dimensional "holistic and structuralist" view of space-time emerges which includes elements common to the tradition of both substantivalism and relationism. The observables of our models undergo real "temporal change" and thereby provide a counter-example to the thesis of the "frozen-time" picture of evolution. (shrink)

The article briefly analyzes the concept of a person, arguing that personhood does not coincide with the actual enjoyment of certain intellectual capacities, but is coextensive with the embodiment of a human individual. Since in PVS patients we can observe a human individual functioning as a whole, we must conclude that these patients are still human persons, even if in a condition of extreme impairment. It is then argued that some forms of minimal treatment may not be futile for these (...) patients; they may constitute a form of respect for their human dignity and benefit these patients, even if they are not aware of that. Moreover, it is important to consider the symbolic significance of care: while many believe that PVS is a kind of imprisonment, for others providing food and fluids is the only way to testify our proximity to these persons. The best policy would be to provide, as a general rule, artificial nutrition and hydration to PVS patients: this treatment could be withdrawn, after a period of observation and reflection by the family and proxies, on the basis of the proxies' objection to the continuation or of the patient's advance directives specifically referring to this situation. (shrink)

1 Department of History and Philosophy of Science, University of Cambridge, Free School Lane, Cambridge, CB2 3RH, UK.

Hume's discussion of the idea of space in his Treatise on Human Nature is fundamental to an understanding of his treatment of such central issues as the existence of external objects, the unity of the self, the relation between certainty and belief, and abstract ideas. Marina Frasca-Spada's rich and original study examines this difficult part of Hume's philosophical writings and connects it to eighteenth-century works in natural philosophy, mathematics and literature. Focusing on Hume's discussions of the infinite divisibility of (...) extension, the origin of the idea of space, geometry, and the notion of a vacuum, she shows that the central questions of Hume's 'science of human nature' - what does the 'science of human nature' reveal about the mind and its operations? what is experience? - underlie all of these discussions. Her analysis points the way to a reassessment of the central current interpretative problems in Hume studies. (shrink)

Di Massimo di Tiro si conoscono pochi dettagli biografici. Le fonti antiche, concordi nel ritenerlo ‘filosofo’ e ‘filosofo platonico’, affermano che le sue dissertazioni o indagini filosofiche sono da ricondursi al suo primo soggiorno a Roma, al tempo dell’imperatore Commodo. Le quarantuno dissertazioni filosofiche di Massimo di Tiro offrono una visione privilegiata della cultura imperiale del secondo secolo, epoca in cui, dominante l’eleganza stilistica, anche la filosofia non disdegnava di dispiegare i propri contenuti mediante il bello stilo dello (...) strumento retorico. Nello svolgimento dei temi, perlopiù platonici nell’ispirazione e orientati ad argomenti presenti al dibattito coevo, ma comunque non escludenti altre influenze filosofiche, Massimo di Tiro si mostra pensatore dalla non banale semplicità. Muovendosi fra filosofia e letteratura, fra Platone e Omero, egli calibra l’erudizione sul filtro di un’esigenza educativa di ampio respiro. Nel volume si presenta la prima traduzione italiana completa dal greco. Il commento critico, aggiornato al dibattito accademico internazionale, mira a mostrare come l’opera del pensatore meriti una rinnovata attenzione nell’ambito degli studi classici letterari e filosofici, giacché nel delineare il quadro culturale del tempo essa consente di meglio precisare alcuni non marginali aspetti del platonismo del secondo secolo. (shrink)

We present an account of semantics that is not construed as a mapping of language to the world but rather as a mapping between individual meaning spaces. The meanings of linguistic entities are established via a “meeting of minds.” The concepts in the minds of communicating individuals are modeled as convex regions in conceptual spaces. We outline a mathematical framework, based on fixpoints in continuous mappings between conceptual spaces, that can be used to model such a semantics. If concepts are (...) convex, it will in general be possible for interactors to agree on joint meaning even if they start out from different representational spaces. Language is discrete, while mental representations tend to be continuous—posing a seeming paradox. We show that the convexity assumption allows us to address this problem. Using examples, we further show that our approach helps explain the semantic processes involved in the composition of expressions. (shrink)

Now classified as mid-way between epistemology and metaphysics, that part of 18th-century ‘science of human nature’ concerned with the investigation of human perceptions and passions was in fact closely allied both to moral and natural philosophy and to medicine. This chapter the roles in the formation of belief that writers in this tradition and authors of novels attributed to the readers' senses and imagination, and to their social intercourse. In particular, it focusses on the relative educational and moral value attributed (...) to history, romance, and novels, and the readers' sympathetic responses to historical and fictional writings as they were represented and discussed in Charlotte Lennox' The Female Quixote, and in David Hume's Treatise of Human Nature. (shrink)

This chapter contains section titled: Hume's Legacy Sense Impressions, Passions and Ideas The Idea of Cause and Effect Probability and the Inference from Past to Future (Moderate) Skepticism Moral Feelings Human Nature and Religious Beliefs.

This essay is on the nature and roles of sense impressions and objects in Hume’s account of perception in the Treatise of Human Nature. I start by considering how Hume introduces sense impressions at the beginning of the Treatise and show that, although he explains the distinction between impressions and ideas on the basis of their different strength and liveliness, the crucial difference between them is in fact that ideas are copies of impressions, while impressions do not, in turn, copy (...) anything. They are what ideas represent, the objects of our thought. But if impressions are non-representative, how can Hume talk about ‘objects’ at all — in fact, what are Humean ‘objects’? This problem is the subject of the present discussion. (shrink)

This contribution offers a reflection on the death penalty in the light of OT Law that enforced and sanctioned it only within the scope of the biblical understanding of justice. Starting therefore with the Torah and moving through the Prophets into the New Testament, the reader is called to question the logic behind retributive justice, as it attempts to re-establish the desecrated order. Retributive justice does so by means of a 'just' punishment, by giving everyone one's due, and through the (...) emendation of the culprit. The cross, though, goes well beyond the understanding of God as symmetry and the concept of a 'matching' justice. In Christ's death, the first place cannot be accorded to an order that needs to be set right again; still less can it be given to the suppression of bad subjects. That first place must belong to the human person who cries out for redemption and asks to be re-created in God's image. This would amount to nothing less than a restitutio principii. (shrink)

The analysis of Hannah Arendt's Socrate opens up the possibility of a fruitful rethinking of the sense and way of conceiving philosophy with children. A way that in this proposal is defined as "Utopian", since it intends to resume, with the Socratic lesson, just how much remains in it open, undetermined, capable of reviving with enchantment in the living of the orality of a philosophical dialogue- absolutely unprecedented and unpredictable - such as that with children. The space given to the (...) unexpected, to listening, to free divergence, then becomes radical, comes to be a paradoxical foundation of a "methodology" that cannot be captured in structured schemes and paths, since it remains open to the "utopian" space of philosophizing. The comparison with Arendt is therefore interleaved, through references to other readings that are contemporary of the Socratic lesson, with the experience lived of the author, who has been leading for years philosophy workshops with primary school children. Of course, Socrates has never been and never wanted to act as a "master": his conducting the dialogue, although always being asymmetric, is aimed at bringing the interlocutor on his line of reasoning and never the opposite, has never had as end the teaching of some doctrine. How much, rather, to lead the interlocutor from the presumed certainty to radical uncertainty, from opinion to doubt, from affirmation to aporia. Thiswe must authentically experiment, before anything else, when we place ourselves inlistening to children's questions, when we try to dialogue with them, to "do philosophy", to "think together". (shrink)