The doctrines and teachings of the Church of Jesus Christ of Latter-day Saints support and even demand a strong environmental ethic. Such an ethic is grounded in the inherent value of all souls and in God’s commandment of stewardship. Latter-day Saint doctrine declares that all living organisms have souls and explicitly states that the ability of creatures to know some degree of satisfaction and happiness should be honored. God’s own concern for the well-being and progress of all life, and His (...) sacrifice through Jesus Christ, illustrate the generous way that He expects His children to exercise their brief stewardship of this world. In addition, the important role nature has played in the religious lives of Latter-day Saint members, from the Prophet Joseph Smith to the present day, argues strongly for wilderness preservation as a spiritual resource for future generations. (shrink)

We report the identification of a recurrent, 520-kb 16p12.1 microdeletion associated with childhood developmental delay. The microdeletion was detected in 20 of 11,873 cases compared with 2 of 8,540 controls and replicated in a second series of 22 of 9,254 cases compared with 6 of 6,299 controls. Most deletions were inherited, with carrier parents likely to manifest neuropsychiatric phenotypes compared to non-carrier parents. Probands were more likely to carry an additional large copy-number variant when compared to matched controls. The clinical (...) features of individuals with two mutations were distinct from and/or more severe than those of individuals carrying only the co-occurring mutation. Our data support a two-hit model in which the 16p12.1 microdeletion both predisposes to neuropsychiatric phenotypes as a single event and exacerbates neurodevelopmental phenotypes in association with other large deletions or duplications. Analysis of other microdeletions with variable expressivity indicates that this two-hit model might be more generally applicable to neuropsychiatric disease. © 2010 Nature America, Inc. All rights reserved. (shrink)

Over the past few decades, significant advances have been made in public engagement with, and the democratization of, science and technology. Despite notable successes, such developments have often struggled to enhance public trust, avert crises of expertise and democracy, and build more socially responsive and responsible science and innovation. A central reason for this is that mainstream approaches to public engagement harbor what we call “residual realist” assumptions about participation and publics. Recent coproductionist accounts in science and technology studies offer (...) an alternative way of seeing participation as coproduced, relational, diverse, and emergent but have been somewhat reluctant to articulate what this means in practice. In this paper, we make this move by setting out a new framework of interrelating paths and associated criteria for remaking public participation with science and democracy in more experimental, reflexive, anticipatory, and responsible ways. This framework comprises four paths to: forge reflexive participatory practices that attend to their framings, emergence, uncertainties, and effects; ecologize participation through attending to the interrelations between diverse public engagements in wider systems; catalyze practices of anticipatory reflection to bring about responsible democratic innovations; and reconstitute participation as constitutive of systems of technoscience and democracy. (shrink)

Brings together and interprets previously hard-to-find texts, new translations and passages detailing the interplay between philosophy and psychopathology.

Whether or not we would be happy to do without sounds, the idea that our expe- rience of sounds is of things which are distinct from the world of material objects can seem compelling. All you have to do to confirm it is close your eyes and reflect on the character of your auditory experience.

Technical results about the time dependence of eigenvectors of reduced density operators are considered, and the relevance of these results is discussed for modal interpretations of quantum mechanics which take the corresponding eigenprojections to represent definite properties. Continuous eigenvectors can be found if degeneracies are avoided. We show that, in finite dimensions, the space of degenerate operators has co-dimension 3 in the space of all reduced operators, suggesting that continuous eigenvectors almost surely exist. In any dimension, even when degeneracies are (...) hit, we find conditions under which a theorem due to Rellich can provide continuous eigenvectors. We use this result to formulate an extended version of the modal interpretation. We also discuss eigenvector instability which we argue poses a serious problem for the modal interpretation, even in our extended version. Many examples are given to illustrate the mathematics. (shrink)

This article surveys recent work in pragmatism and political theory. In doing so, it shows both how recent work on pragmatism has secured the view that at its core is a set of arguments about the character of democracy – although the character of those arguments is open to debate and reimagination – and how pragmatist arguments have been reinterpreted and deployed to address contemporary concerns and approaches. This charts a terrain of live disagreements rather than settled opinion.

In the attempt to understand the norms governing believers, epistemologists have tended to focus on individual belief as the primary object of epistemic evaluation. However, norm governance is often assumed to concern, at base, things we can do as a free exercise or manifestation of our agency. Yet believing is not plausibly conceived as something we freely do but rather as a state we are in, usually as the mostly automatic or involuntary result of cognitively processes shaped by nature, bias, (...) and ideology. In this paper, I sketch a response to this tension. This response is based on rejecting the traditional theoretical focus on an individual’s particular beliefs as the primary object of normative epistemic evaluation. If we shift our focus from the particular beliefs of individuals to the community and its information managing practices, we may lessen the tension between norm governance and automaticity and involuntariness in a way that construes autonomous cognitive agency as a resultant of rather than a precondition for our norm-governed epistemic sociality. (shrink)

The analysis and defence of democracy on the grounds of its epistemic powers is now a well-established, if contentious, area of theoretical and empirical research. This article reconstructs a distinctive and systematic epistemic account of democracy from Dewey’s writings. Running like a thread through this account is a critical analysis of the distortion of hierarchy and class division on social knowledge, which Dewey believes democracy can counteract. The article goes on to argue that Dewey’s account has the resources to defuse (...) at least some important forms of the broader charges of instrumentalism and depoliticization that are directed at the epistemic project. The gloomy conviction of the stratified character of capitalist societies and the conflictual character of their politics shapes Dewey’s view of political agency, and this article outlines how this epistemic conception of democracy is deployed as a critical standard for judging and transforming existing political forms but also serves as a line of defence for democratic political forms against violent and authoritarian alternatives. (shrink)

Daniel Dennett is one of the most influential thinkers at the interface between philosophy and science. This book is the first comprehensive examination of Dennett ’s ideas on the nature of thought, consciousness, free will, and the significance of Darwinism. A highly original introduction to contemporary thinking about the relationship between mind and science. This is the first comprehensive examination of Dennett ’s ideas on the nature of thought, consciousness, free will, and the significance of Darwinism. Examines Dennett ’s unique (...) response to the question of when and how science should affect the conception that we have of ourselves. Casts new light on specific controversies: Could robots ever think, feel, and enjoy freedom? Does Dennett really explain consciousness? Are mental states real or merely ‘useful fictions’? Do we have free will? Is the self a ‘centre of narrative gravity’? (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Philosophy, Psychiatry, & Psychology 11.1 (2004) 35-41 [Access article in PDF] The Rationality of Psychosis and Understanding the Deluded Matthew R. Broome Campbell's important and influential paper (Campbell 2001) has framed the debate that Bayne and Pacherie (2004) most explicitly, and Klee (2004) and Georgaca (2004) more implicitly, engage in. Campbell has offered two broad ways of thinking about explanations of delusions—the empirical and the rational. He offers (...) some criticism of the former and an endorsement of the latter. Campbell uses examples from clinical psychopathology to illustrate his argument and Bayne and Pacherie in turn employ these. Campbell discusses the eponymously named delusions of Capgras and Cotard—the former a subtype of delusional misidentification and the latter a delusion whose content is colored predominantly with nihilistic and possibly hypochondriacal themes. Campbell, Bayne and Pacherie, and Klee discuss the empirical data in relation to such delusions and as an aid to discussing the empirical model more generally. It does seem a little unfortunate that these delusions, which are less than typical, become the focus of Campbell's paper, and Bayne and Pacherie's criticism of his work. Delusions are remarkably heterogeneous; this indeed may be part of the reason why there is so much difficulty in reaching a definition as Klee discusses, and occur in a wide variety of mental and neurological illnesses. The most common delusions are those of persecution and reference (World Health Organization [WHO] 1973) and typically occur in schizophrenia. By contrast, delusional misidentification occurs most commonly in patients with dementia, delirium, and focal cognitive impairment, but can occur in other functional psychoses such as an affective or schizophrenic psychosis. The most common form of delusional misidentification is not that of either the exotic Capgras or Fregoli syndromes but delusional misidentification for place; thus, although Bayne and Pacherie's arguments against Campbell may still hold, delusional misidentification tends to occur in the context of a patient believing that they are at home or on holiday rather than in hospital and may not necessarily involve close family members or other intimate relationships. Similarly, Cotard's syndrome tends to occur in the context of a severe depressive illness with mood-congruent psychotic symptoms, typically in an elderly individual. It does not have to have the content that the deluded is dead, but can include beliefs, for example, that the world no longer exists or that their internal organs are not present. Thus, a patient with either Capgras' or Cotard's syndrome is likely to differ from patients with delusions of persecution. They would [End Page 35] have different diagnoses, probably be older, and have a greater likelihood of structural abnormalities of the brain on imaging and consequent neuropsychological dysfunction. That is not to say that patients with schizophrenia have normal cerebral anatomy and neuropsychology, but rather that the Capgras' and Cotard's patients are likely to have neurological quality to their presentation that is clinically relevant, rather than what commonly the case in schizophrenia and the other functional psychoses, where the neurological abnormalities are only currently important at the level of academic research. Empirical Models of Delusion Formation Different delusions may not have that much in common, nor may the patients who believe in them. This in turn relates to the empirical paradigm that both Campbell and Bayne and Pacherie discuss. It is true that current research, and indeed the clinical practice of cognitive behavioral therapy for psychosis, is indebted to the work of Maher and it is within his legacy which we work. This, however, is not to say that we think his initial formulation was correct. Maher's (1988, 1992) work focused attempts in explaining delusions—both to support and refute his thesis that delusions are the consequence of normal cognitive mechanisms seeking to explain an anomalous sensory experience. Such a view initially led to work demonstrating delusions in the absence of anomalous perceptions, the presence of reasoning biases in the deluded population, and the possibility that abnormal sensory experience may be consequent upon biased cognitive processes (Garety and Freeman 1999). More recent work has demonstrated the prevalence of... (shrink)

We focus on the production of efficient descriptions of objects, actions and events. We define a type of efficiency, textual economy, that exploits the hearer’s recognition of inferential links to material elsewhere within a sentence. Textual economy leads to efficient descriptions because the material that supports such inferences has been included to satisfy independent communicative goals, and is therefore overloaded in the sense of Pollack [18]. We argue that achieving textual economy imposes strong requirements on the representation and reasoning used (...) in generating sentences. The representation must support the generator’s simultaneous consideration of syntax and semantics. Reasoning must enable the generator to assess quickly and reliably at any stage how the hearer will interpret the current sentence, with its (incomplete) syntax and semantics. We show that these representational and reasoning requirements are met in the SPUD system for sentence planning and realization. (shrink)

How come quantum theory has anything to do with mind? Is your theory refutable? What is the point of all the technical detail? Do you suggest that the operation of the brain involves large scale quantum coherence? Isn't large scale quantum coherence necessary to solve the problem of the unity of consciousness? How does a many-minds interpretation survive Occam's razor? What, briefly, is your current philosophical position? What is your understanding of the relationship between mind and brain for split-brain patients? (...) Do you believe that the mind can survive the death of the brain? No journal reference is given for several of the recent papers on your home page. Where will these papers be printed? How are the “source” and “pdf” versions of the papers on your home page produced and viewed? Why does the page with your photograph behave oddly in some browsers? Where can I find an elementary introduction to the interpretation of quantum theory? Doesn't decoherence theory solve all the problems of the interpretation of quantum theory? How do the ambiguities of decoherence affect the many-worlds interpretation? Could you expand on your answers to the two previous questions? Why isn't the conventional interpretation of quantum theory adequate? What about the Bohm interpretation? What about consistent histories? Does the present many-minds interpretation solve all the problems? (shrink)

This article examines the relationship of pragmatism to the theory of deliberative democracy. It elaborates a dilemma in the latter theory, between its deliberative or epistemic and democratic or inclusive components, and distinguishes responses to this dilemma that are internal to the conception of deliberation employed from those that are external. The article goes on to identify two models of pragmatism and critically examines how well each one deals with the tension identified in deliberative democracy.

While it is often supposed that Spinoza understood a life of virtue as one of pure activity, with as few passions as possible, this paper aims to make explicit how the passions for Spinoza contribute positively to our virtue. This requires, first, explaining how a passion can increase our power, given Spinoza’s view on the passions generally, which, in turn, requires coming to terms with the problem of passive pleasure, that is, the problem of explaining how being passive can cause (...) an increase in our power. In brief, this paper will argue that, for Spinoza, even when we are passive, we are somewhat active or, in Spinoza’s language, “adequate” to varying degrees. The passions represent activity because they exercise our understanding by providing us with intelligence about external bodies and our own bodies, in particular, the degree of our bodies’ perfection. It follows that a passion can be sufficiently adequate to bring about an increase in one’s power; in this sense, they can be virtuous. Moreover, this paper will show that the passions can also be virtuous in a moral sense. The view goes roughly as follows: according to Spinoza, the passions serve as a measure of our perfection. Consequently, they play a necessary role in moral reasoning, by indicating which activities increase or hinder our virtue. On this view, a truly virtuous person would require the passions in order to engage consistently in the sorts of activities which increase her power, in particular, following reason. Since this sort of consistency in behavior is necessary for a virtuous character, the passions can be virtuous in the sense that they are necessary aspects of the sort of character which disposes us to act according to reason. (shrink)

This thesis argues that the strongest account of moral rights entails that animals and other marginal cases hold rights. The thesis contends that mutual advantage social contract theories offer the strongest account of rights from a security perspective, and that such theories entail rights for animals and marginal cases. Both of these claims are widely contested. Chapter 1 examines the fundamental elements of a social contract theory as developed by Hobbes and Hume. Chapter 2 revises the fundamental elements of contract (...) theory to make them more persuasive, and derives from them an account of rights for animals and marginal cases. Chapter 3 examines the most plausible competing accounts of rights for animals and marginal cases: utilitarianism, neo-Kantianism, and capability theory. Chapter 4 argues that the mutual advantage account of rights is better than the leading competitors from a security perspective. (shrink)

This paper addresses the political constraints on science through a pragmatist critique of Philip Kitcher’s account of “well-ordered science.” A central part of Kitcher’s account is his analysis of the significance of items of scientific research: contextual and purpose-relative scientific significance replaces mere truth as the aim of inquiry. I raise problems for Kitcher’s account and argue for an alternative, drawing on Peirce’s and Dewey’s theories of problem-solving inquiry. I conclude by suggesting some consequences for understanding the proper conduct of (...) science in a democracy. (shrink)

We “prepunish” a person if we punish her prior to the commission of her crime. This essay discusses our intuitions about the permissibility of prepunishment and the relationship between prepunishment and compatibilism about free will and determinism. It has recently been argued that compatibilism has particular trouble generating a principled objection to prepunishment. The failure to provide such an objection may be a problem for compatibilism if our moral intuitions strongly favor the prohibition of prepunishment. In defense of compatibilism, I (...) argue that while no objection to prepunishment is entailed by the central tenets of compatibilism, this does not necessarily show that compatibilism conflicts with our moral intuitions. And while there may be no distinctly compatibilist objection to prepunishment, there are common-sense objections to prepunishment of which the compatibilist can make use, at least under actual-world circumstances. And, while these common-sense objections might be inoperative in certain non-actual circumstances, it is not clear that support for prepunishment would be unintuitive in these circumstances. (shrink)

This paper provides a brief critical assessment of Ruger’s global health justice framework.

The cognitive hierarchy model is an approach to decision making in multi-agent interactions motivated by laboratory studies of people. It bases decisions on empirical assumptions about agents’ likely play and agents’ limited abilities to second-guess their opponents. It is attractive as a model of human reasoning in economic settings, and has proved successful in designing agents that perform effectively in interactions not only with similar strategies but also with sophisticated agents, with simpler computer programs, and with people. In this paper, (...) we explore the qualitative structure of iterating best response solutions in two repeated games, one without messages and the other including communication in the form of non-binding promises and threats. Once the model anticipates interacting with sufficiently sophisticated agents with a sufficiently high probability, reasoning leads to policies that disclose intentions truthfully, and expect credibility from the agents they interact with, even as those policies act aggressively to discover and exploit other agents’ weaknesses and idiosyncrasies. Non-binding communication improves overall agent performance in our experiments. (shrink)

This paper gives a new, proof-theoretic explanation of partial-order reasoning about time in a nonmonotonic theory of action. The explanation relies on the technique of lifting ground proof systems to compute results using variables and unification. The ground theory uses argumentation in modal logic for sound and complete reasoning about specifications whose semantics follows Gelfond and Lifschitz’s language. The proof theory of modal logic A represents inertia by rules that can be instantiated by sequences of time steps or events. Lifting (...) such rules introduces string variables and associates each proof with a set of string equations; these equations are equivalent to a set of partial-order tree-constraints that can be solved efficiently. The defeasible occlusion of inertia likewise imposes partial-order constraints in the lifted system. By deriving an auxiliary partial order representation of action from the underlying logic, not the input formulas or proofs found, this paper strengthens the connection between practical planners and formal theories of action. Moreover, the general correctness of the theory of action justifies partial-order representations not only for forward reasoning from a completely specified start state, but also for explanatory reasoning and for reasoning by cases. (shrink)