To date, the effective management of HIV‐1 infection by anti‐retroviral drugs has proved remarkably difficult to achieve. This is primarily due to the ease with which HIV‐1 becomes resistant to drugs which initially may be very effective at blocking viral replication. In a recent issue of Science, two promising new AIDS treatments were reported. The first described the use of retroviral‐type zinc finger structures found in the HIV‐1 nucleocapsid protein as targets for anti‐retroviral drugs(1). The second demonstrated the feasibility of (...) the reverse transcriptase inhibitor (R)‐9‐(2‐phosphonylmethoxypropyl) adenine as a postexposure prophylaxis in blocking HIV‐1 infection(2). (shrink)

Compatibilism combines an externalist view of mental content with a doctrine of privileged self‐knowledge. The essay presents a reductio of compatibilism by arguing that if compatibilism were true, we would be in a position to know certain facts about the world a priori, facts that no one can reasonably believe are knowable a priori. Whether this should be taken to cast doubt on externalism or privileged self‐knowledge is not discussed. Consideration is given to the ’empty case’—the case in which a (...) thinker expresses what he takes to be a genuine thought concerning a natural kind but where there is in fact no relevant natural kind, so that the putative natural kind term fails to refer. It is argued that, in such a case, on an externalist conception of natural kind terms, the thinker is deluded in taking himself to be expressing a complete thought, and that such delusions are not compatible with privileged self‐knowledge. (shrink)

The question I want to look at in this paper is this: To what extent does an externalist conception of mental content threaten our ability to know the contents of our thoughts? I shall argue that, in an important sense, externalism is inconsistent with the thesis that we have authoritative first-person knowledge of thought content: in particular, I shall argue, it is inconsistent with the thesis that our thought contents are epistemically transparent to us. I shall further argue that this (...) is true in a sense that falsifies another important and traditionally fundamental view —that we can detect a priori whether our inferences are logically valid or not. I shall leave for another occasion the question whether these results reflect badly on epistemic transparency or on externalism. (shrink)

Samuelson's text was first published in 1948, and it immediately became the authority for the principles of economics courses. The book continues to be the standard-bearer for principles courses, and this revision continues to be a clear, accurate, and interesting introduction to modern economics principles. Bill Nordhaus is now the primary author of this text, and he has revised the book to be as current and relevant as ever.

This volume presents a series of influential essays by Paul Boghossian on the theory of content and on its relation to the phenomenon of a priori knowledge. The essays are organized under four headings: the nature of content; content and self-knowledge; knowledge, content, and the a priori; and colour concepts.

A suggestion famously made by Peter Winch and carried through to present discussions holds that what constitutes the social as a kind consists of something shared – rules or practices commonly learned, internalized, or otherwise acquired by all members belonging to a society. This essays argues against the explanatory efficacy of appeals to this shared something as constitutive of a social kind by examining a violation of social norms or rules, viz., mistakes. I argue that an asymmetric relation exists between (...) the notion of mistakes and that of the social. In particular, mistakes do not presuppose a concept of the social, but the concept of the social requires prior specification of a category of mistakes. But no such prior specification proves possible. The very notion of a mistake is so inchoate that it makes it impossible to provide the kind of regimentation required for a rule-governed domain. Thus, there may be recognized mistakes even in the absence of a unified system or common knowledge of norms.Later writers attempt to avoid Winch's over-strong assumption that something shared and internal constitutes the social but cannot. Extending recent work by Stephen Turner, I argue that ``the social'' is not a domain that is susceptible to lawlike treatment, but rather a heterogeneous, motley collection. For absent the assumption of a shared something, no social object exists to be explained. So, I conclude, we have at present no clear way of marking out the social as a coherent or unified domain of inquiry. (shrink)

This article explores and attempts to resolve some issues that arise when psychoanalytic explanations are construed as a type of historical or narrative explanation. The chief problem is this: If one rejects the claim of narratives to verisimilitude, this appears to divorce the notion of explanation from that of truth. The author examines, in particular, Donald Spence's attempt to deal with the relation of narrative explanations and truth. In his critique of Spence's distinction between narrative truth and historical truth, the (...) author develops some suggestions regarding the role of truth in narrative explanations. (shrink)

Only in recent years have developmental psychologists begun advocating and exploring dual-process theories and their applicability to cognitive development. In this paper, a dual-process model of developments in two processing systems—an “analytic” and an “experiential” system—is discussed. We emphasise the importance of “metacognitive intercession” and developments in this ability to override experiential processing. In each of two studies of sunk cost decisions, age-related developments in normative decisions were observed, as were declines in the use of a “waste not” heuristic. In (...) the second study, children and adolescents were presented with arguments for normative and non-normative sunk cost decisions. Following argument evaluation, participants were re-presented the original problems and a set of novel, transfer problems. Results indicated that post-argument improvements were most apparent during adolescence. Age-related improvements were most noticeable on the transfer problems. In general, the findings suggest that the ability to metacognitively intercede (i.e., reflect on arguments; inhibit experientially produced responses) emerges towards middle adolescence. However, even by the end of adolescence, in the absence of significant contextual cues and motivation, this ability is infrequently utilised. (shrink)

In this chapter a new problem about rule-following is outlined, one that is distinct both from Kripke’s and Wright’s versions of the problem. This new problem cannot be correctly responsed to, as Kripke’s can, by invoking Wright’s Intentional Account of rule-following. The upshot might be called, following Kant, an antinomy of pure reason: we both must — and cannot — make sense of someone’s following a rule. The chapter explores various ways out of this antinomy without here endorsing any of (...) them. (shrink)

In the latest edition of their popular overview text, Erickson and Murphy continue to provide a comprehensive, affordable, and accessible introduction to anthropological theory from antiquity to the present.

The Universe is One places the ancient synthesis of Stoicism, Platonism, Judaism, and Christianity in active dialogue with modern process science in order to conjoin science, philosophy, and theology into the human quest for meaning. Paul A. Olivier proposes a comprehensive theory of knowledge, which he expands into a theory of life, correlating modern process science and the western-Judeo-Christian heritage into a grand theory of the Universe. He brings together the ideas of influential thinkers from the world of science (...) with those from the world of New Testament studies. Olivier clearly explains concepts from diverse fields to construct a satisfying theory of knowledge and life. He accomplishes this through an examination of the dominance of polarity in all aspects of the universe, such as chaos and order, predictability and unpredictability. Through this complex blend of opposites Olivier develops his theory as an interaction of Word and Spirit that provides the Universe with everything necessary to account for its creation and ongoing evolution. The Universe continually creates and sustains itself out of its own internal necessity coupled paradoxically with the fluidity of its own inherent unpredictability. (shrink)

One prominent argument against the use of preimplantation genetic diagnosis to select a deaf embryo with the aim of creating a deaf child is that it violates the child’s right to an open future. This paper challenges the open future argument against deaf embryo selection, criticizing its major premise that deafness limits a child’s opportunity range in ways that compromise their future autonomy. I argue that this premise is not justified and is supported by negative presumptions about deaf embodiments that (...) are suspect and in need of further argumentation. First, available interpretations of the open future concept fail to justify the devaluation of deaf traits as inherently autonomy-diminishing. Second, arguing against deaf embryo selection requires demonstrating that a deaf trait generally constrains opportunity ranges independent of social context. But such analyses neglect important social and relational components of autonomy. For these reasons, merely appealing to the child’s right to an open future does not sufficiently support the conclusion that deaf embryo selection is wrong. (shrink)

Over the past thirty years, the doctrine of informed consent has become a focal point in discussions of medical ethics. The literature of informed consent explores the evolution of the principle of autonomy, purportedly emerging from the mists of 19th Century medical practice, and finding its earliest articulation in legal cases where wronged citizens asserted their rights against medical authority. A commonplace, if not obligatory, feature of that literature is a reference to the case of Mary Schloendorff and the opinion (...) written by Judge Benjamin Cardozo by which the case is remembered. Commentators today applaud the prescience of Cardozo for an early articulation of what eventually would become bioethical orthodoxy concerning informed consent and its place as a bulwark of patient autonomy. They inevitably quote Cardozo's famous statement, “Every human being of adult years and sound mind has a right to determine what shall be done with his own body.”. (shrink)

In this article, Whitehead's transition from a Philosophy of Evolution to a Philosophy of Organism is studied primarily on the basis of the evidence provided by the first two volumes of The Harvard Lectures of Alfred North Whitehead, especially the second volume that deals with the period 1925–1927 and that is subtitled General Metaphysical Problems of Science.

Philosophers and ethicists debate this controversial moral principle illustrating its application to current moral dilemmas such as war, suicide, nuclear power, affirmative action, and morphine use for terminal cancer patients.

When Benjamin Franklin suggested that man is by nature a tool-making animal, he summed up what was for his fellow Americans the common sense of the matter. It is not, then, surprising that, when Britain's colonists in North America broke with the mother country over the issue of an unrepresentative parliament's right to tax and govern the colonies, they defended their right to the property they owned on the ground that it was in a most thorough-going sense an extension of (...) themselves: the fruits of their own labor. This understanding they learned from John Locke, who based the argument of his Two Treatises of Government on the unorthodox account of providence and of man's place within the natural world that Sir Francis Bacon had been the first to articulate. All of this helps explain why the framers of the American constitution included within it a clause giving sanction to property in ideas of practical use. (shrink)

For nearly a century, and until very recently, the majority of U.S. states required a blood test for marriage license applicants. The tests identified people with conditions formerly designated as "venereal diseases," most importantly gonorrhea and syphilis. Those who tested positive were barred from civil marriage. Although the premarital testing requirement is no longer a feature of state law, numerous related enactments are common features of law in most states.The historical literature describing the rise and fall of laws prescribing marriage (...) restrictions related to VD has treated those enactments as public health measures, meant primarily to forestall the spread of disease to intimate partners. But laws to... (shrink)

Matthew Lipman befriended me at an APA meeting in 1974. Through more than twenty years of phone calls, I got to chat with, consult with, and learn from Matt the details and challenges of developing philosophy for children. He acknowledged that I convinced him that the program needed “branding,” lest anyone present similar-sounding programs—some of which might be good and others not. He got a snippet of a video of my teaching troubled sixth-graders with his book Harry Stottlemeier’s Discovery on (...) the Today Show with Bryant Gumbel. That did much to shape my future, as did branding for sustaining Matt’s program. Lipman and I spoke by phone several times every year from 1976 until the mid-1990s. (shrink)

W. V. Quine was the most important naturalistic philosopher of the twentieth century and a major impetus for the recent resurgence of the view that empirical science is our best avenue to knowledge. His views, however, have not been well understood. Critics charge that Quine’s naturalized epistemology is circular and that it cannot be normative. Yet, such criticisms stem from a cluster of fundamental traditional assumptions regarding language, theory, and the knowing subject – the very presuppositions that Quine is at (...) pains to reject. Through investigation of Quine’s views regarding language, knowledge, and reality, the author offers a new interpretation of Quine’s naturalism. The naturalism/antinaturalism debate can be advanced only by acknowledging and critiquing the substantial theoretical commitments implicit in the traditional view. Gregory argues that the responses to the circularity and non-normativity objections do just that. His analysis further reveals that Quine’s departure from the tradition penetrates the conception of the knowing subject, and he thus offers a new and engaging defence of Quine’s naturalism. (shrink)

Following Oliver Ramsbotham’s observation that conflict resolution and analysis have not taken radical disagreement seriously enough, and in light of his lament that he has not yet found an adequate philosophy of radical disagreement, this article claims that the philosophy of Alasdair MacIntyre provides some coreelements of any adequate philosophy of radical disagreement. MacIntyre’s theory suggests that the problem of radical disagreement is in fact more radical thanRamsbotham affirms. Ramsbotham’s account of the strategic engagement of discourses (SED) approach is critiqued (...) in light of MacIntyre’s diagnosis of radical disagreement, which calls into question its theoretical and philosophical basis. The main problem is held to be that of internal radical disagreement, which SED appears to skirt over. This is elucidated through a brief exploration of two philosophical approaches to moral-political disagreement in relation to Israeli peace activism and the Colombian conflict. (shrink)

Riddles of induction – old or new, Hume’s or Goodman’s – pose unanswered challenges to assumptions that experiences logically legitimate expectations or classifications. The challenges apply both to folk beliefs and to scientific ones. In particular, Goodman’s ‘new riddle’ famously confounds efforts to specify how additional experiences confirm the rightness of currently preferred ways of organizing objects, i.e. our favored theories of what kinds there are.1 His riddle serves to emphasize that neither logic nor experience certifies accepted groupings of objects (...) into kinds.2 Hacking strongly endorses Goodman’s riddle and its chief consequences – nature does not dictate any organizing scheme to us, and different schemes need have no connection to one another. (shrink)

In this article, I show how traditional Thomistic claims about the creation and fall of the first human beings—or “Adam”—are compatible with the claims of evolutionary science concerning human origins. Aquinas claims that God created Adam in a state or condition of original justice, wholly subject to God and so fully virtuous, as well as internally immune to bodily corruption, suffering, and natural death. In defense of “Aquinas's Adam,” I first argue that affirming that the prelapsarian Adam was internally immune (...) to suffering and death does not require denying that these things predated his emergence within evolutionary history, or that he would have faced real challenges posed to him by his natural environment. Next, I rebut the claim that Adam must have been spiritually and morally fragile, given the traits he inherited from his evolutionary ancestors. Finally, I dispute the claim that Adam only could have fallen if he existed in a spiritually and morally fragile state. (shrink)

There has been a distinct trend in modern thought to be deeply suspicious and critical of the human mind's ability to gain genuine access to any reality that transcends the world or the mind. As such, much modern reflection on the mind's relationship to a transcendent God has either banished God from the realm of the cognitively accessible or found ways to evacuate God of his transcendence, and reduce God to a concept or idea in the mind. In this book, (...) I directly challenge negative modern understandings of the mind's relationship to God, and advance the provocative claim that the human mind is not "bounded" on the outside but actually remains "open" to the world and to God. As such, the mind is able to know the world and God with varying degrees of objectivity. I turn to Thomas Aquinas in order to explicate as well as defend important claims that Aquinas makes about human cognition as well as our knowledge of God. (shrink)