Cinematic content plays a crucial role in shaping and reflecting societal attitudes, offering powerful narratives that can influence public perceptions of social issues. This study explores the impact of cinematic content on psychological attitudes towards social issues among college students. A sample of 150 students was divided into two groups: Group A (80 students) impacted the positive attitude while Group B (70 students) served as the control group with negative attitude. This study aimed to assess how cinematic narratives affect attitudes (...) and perceptions of social issues. Statistical methods employed included t-tests to compare attitudes between groups, one-way ANOVA for with-group variations, chi-square tests for categorical relationships, and pre-post tests to measure changes in attitudes. The findings highlight the significant role of cinematic content in shaping the attitudes towards social issues, emphasizing the importance of understanding how films influence public opinion and societal norms. This analysis provides insights into the effectiveness of cinematic portrayals in driving the positive social change and informs content creators on leveraging media for educational and advocacy purposes. (shrink)

This study explores the emotional patterns experienced by young musicians before performing and examines how their emotional beliefs influence these pre-performance emotions. A total of 320 students aged 10 to 18 years participated, recalling their most recent concert memory through a guided imagery induction. A selection of 10 emotional patterns was used to assess their feelings, and they selected Happy, Sad, Courageous, Angry, Elated, Inquisitive, Bored, Calm, Tired, and Afraid. They also responded to questions about their opinions regarding musical performance (...) nervousness (MPN), including MPN utility, MPN regulation, and audience attitude. The cluster analysis revealed distinct emotional profiles categorized into Llow MPN, Moderate MPN, and high MPN. Findings showed that beliefs regarding the negative impact of MPN, perceived inefficacy in managing anxiety, and pressure from an unsupportive audience were associated with high and moderate MPN profiles. The study discusses the practical implications for music education based on these insights. (shrink)

In Knowledge and Its Limits Timothy Williamson argues against the luminosity of phenomenal states in general by way of arguing against the luminosity of feeling cold, that is, against the view that if one feels cold, one is at least in a position to know that one does. In this paper I consider four strategies that emerge from his discussion, and argue that none succeeds.

An interview with Anthony Freeman, in which one of the original authors of ‘The Science of Art’ [JCS, 6, No. 6/7, 1999] responds to to ongoing commentary.

In his influential paper 'Speaker's Reference and Semantic Reference', Kripke defends Russell's theory of descriptions against the charge that the existence of referential and attributive uses of descriptions reflects a semantic ambiguity. He presents a purely defensive argument to show that Russell's theory is not refuted by the referential usage and a number of methodological considerations which apparently tell in favour of Russell's unitary theory over an ambiguity theory. In this paper, I put forward a case for the ambiguity theory (...) that thwarts Kripke's defensive strategy and argue that it is not undermined by any of his methodological points. (shrink)

Tracking accounts of knowledge were originally motivated by putative counter-examples to epistemic closure. But, as is now well known, these early accounts have many highly counterintuitive consequences. In this note, I motivate a tracking-based account which respects closure but which resolves many of the familiar problems for earlier tracking account along the way.

We present a theory of human artistic experience and the neural mechanisms that mediate it. Any theory of art has to ideally have three components. The logic of art: whether there are universal rules or principles; The evolutionary rationale: why did these rules evolve and why do they have the form that they do; What is the brain circuitry involved? Our paper begins with a quest for artistic universals and proposes a list of ‘Eight laws of artistic experience’ -- a (...) set of heuristics that artists either consciously or unconsciously deploy to optimally titillate the visual areas of the brain. One of these principles is a psychological phenomenon called the peak shift effect: If a rat is rewarded for discriminating a rectangle from a square, it will respond even more vigorously to a rectangle that is longer and skinnier that the prototype. We suggest that this principle explains not only caricatures, but many other aspects of art. Example: An evocative sketch of a female nude may be one which selectively accentuates those feminine form-attributes that allow one to discriminate it from a male figure; a Boucher, a Van Gogh, or a Monet may be a caricature in ‘colour space’ rather than form space. Even abstract art may employ ‘supernormal’ stimuli to excite form areas in the brain more strongly than natural stimuli. Second, we suggest that grouping is a very basic principle. The different extrastriate visual areas may have evolved specifically to extract correlations in different domains , and discovering and linking multiple features into unitary clusters -- objects -- is facilitated and reinforced by direct connections from these areas to limbic structures. In general, when object-like entities are partially discerned at any stage in the visual hierarchy, messages are sent back to earlier stages to alert them to certain locations or features in order to look for additional evidence for the object . Finally, given constraints on allocation of attentional resources, art is most appealing if it produces heightened activity in a single dimension rather than redundant activation of multiple modules. This idea may help explain the effectiveness of outline drawings and sketches, the savant syndrome in autists, and the sudden emergence of artistic talent in fronto-temporal dementia. In addition to these three basic principles we propose five others, constituting a total of ‘eight laws of aesthetic experience’. (shrink)

A t first glance you might not noorder, which afflicts about 0.5 percent of tice anything odd on meeting a American children. Neither researcher young boy with autism. But if had any knowledge of the other’s work, you try to talk to him, it will and yet by an uncanny coincidence each quickly become obvious that gave the syndrome the same name: autism, something is seriously wrong. He may not which derives from the Greek word autos, make eye contact with (...) you; instead he may meaning “self.” The name is apt, because avoid your gaze and fidget, rock his body the most conspicuous feature of the disorto and fro, or bang his head against the der is a withdrawal from social interacwall. More disconcerting, he may not be tion. More recently, doctors have adopted able to conduct anything remotely resemthe term “autism spectrum disorder” to bling a normal conversation. Even though make it clear that the illness has many rehe can experience emotions such as fear, lated variants that range widely in severity rage and pleasure, he may lack genuine but share some characteristic symptoms. empathy for other people and be oblivious Ever since autism was identified, reto subtle social cues that most children searchers have struggled to determine would pick up effortlessly. what causes it. Scientists know that sus- In the 1940s two physicians—Americeptibility to autism is inherited, although.. (shrink)

Summary Ideomotor apraxia is a cognitive disorder in which the patient loses the ability to accurately perform learned, skilled actions. This is despite normal limb power and coordination. It has long been known that left supramarginal gyrus lesions cause bilateral upper limb apraxia and it was proposed that this area stored a visualkinaesthetic image of the skilled action, which was translated elsewhere in the brain into the pre-requisite movement formula. We hypothesise that, rather than these two functions occurring separately, both (...) are complementary functions of chains of ‘‘mirror neurons’’ within the left inferior parietal lobe. We go on to propose that this neural mechanism in the supramarginal gyrus and its projection zones, which originally evolved to allow the creation of a direct map between vision and movement, was subsequently exapted to allow other sorts of cross-domain mapping and in particular those sorts of abstract re-conceptualisation, such as metaphor, that make mankind unique. (shrink)

(1) The induced colours led to perceptual grouping and pop-out, (2) a grapheme rendered invisible through ‘crowding’ or lateral masking induced synaesthetic colours — a form of blindsight — and (3) peripherally presented graphemes did not induce colours even when they were clearly visible. Taken collectively, these and other experiments prove conclusively that synaesthesia is a genuine percep- tual phenomenon, not an effect based on memory associations from childhood or on vague metaphorical speech. We identify different subtypes of number–colour synaesthesia (...) and propose that they are caused by hyperconnectivity between col- our and number areas at different stages in processing; lower synaesthetes may have cross-wiring (or cross-activation) within the fusiform gyrus, whereas higher synaesthetes may have cross-activation in the angular gyrus. This hyperconnec- tivity might be caused by a genetic mutation that causes defective pruning of con- nections between brain maps. The mutation may further be expressed selectively (due to transcription factors) in the fusiform or angular gyri, and this may explain the existence of different forms of synaesthesia. If expressed very diffusely, there may be extensive cross-wiring between brain regions that represent abstract concepts, which would explain the link between creativity, metaphor and synaesthesia (and the higher incidence of synaesthesia among artists and poets). Also, hyperconnectivity between the sensory cortex and amygdala would explain the heightened aversion synaesthetes experience when seeing numbers printed in the ‘wrong’ colour. Lastly, kindling (induced hyperconnectivity in the temporal lobes of temporal lobe epilepsy [TLE] patients) may explain the purported higher incidence of synaesthesia in these patients. We conclude with a synaesthesia-based theory. (shrink)

This paper examines a neglected puzzle about conditionals: namely, the fact that each of a pair of conditionals with incompatible consequents, [A > C] and [B > C*], may be properly affirmable in circumstances when one does not believe, and is not entitled to infer, the denial of the conjunction of the antecedents, i.e. ~(A & B). The puzzle is why this should be so, since the conditionals entail the conjunction on the popular accounts of conditionals. I present a pragmatic (...) solution which distinguishes between two levels of affirmability. (shrink)

Academic dishonesty presents in different forms, including fabrication of data, falsifying references, multiple submissions, collusion, and sabotage, with two forms haunting academia, namely plagiarism and contract cheating or ghost writing. These latter forms have received considerable attention and have been subjects for research. This interview-based study provides some further insight into the problem of ghost writing through presenting the attitudes, justifications and networking practices of some hired ‘ghost-writers’ from a developing country and discusses the depth of this emerging threat to (...) the academic community.Initially, through simple internet searches using specific keywords, an array of professional advertisements selling contract writing services were identified. Some of these promotional advertisements were found in Facebook® posts, and/or Twitter® feeds. The second part of this study presents a summary of findings from interviews of a group of ghost-writers including their background, attitude and justifications for setting up this new business. The study identifies several high calibre post-graduates who have come to understand the Western (European/north American/australian) ways of scientific writing and have produced a network of ‘consultancy’ services. Although the birth of their business was ad-hoc, they have established a good network and are now able to share projects and practices. Many of them offer services to home and foreign students with varied levels of customer focus. Some of them are even using Turnitin© software to identify text matching issues. This study suggests that these paper mills have widely been subscribed to by students. The article finally discusses wider issues arising from these interviews and proposes some ways of tackling this new threat to academia. (shrink)

(1) The table is covered with books. (2) There is exactly one table and it is covered with books.

Almost everyone who has a limb amputated will experience a phantom limb--the vivid impression that the limb is not only still present, but in some cases, painful. There is now a wealth of empirical evidence demonstrating changes in cortical topography in primates following deafferentation or amputation, and this review will attempt to relate these in a systematic way to the clinical phenomenology of phantom limbs. With the advent of non-invasive imaging techniques such as MEG (magnetoencephalogram) and functional MRI, topographical reorganization (...) can also be demonstrated in humans, so that it is now possible to track perceptual changes and changes in cortical topography in individual patients. We suggest, therefore, that these patients provide a valuable opportunity not only for exploring neural plasticity in the adult human brain but also for understanding the relationship between the activity of sensory neurons and conscious experience. We conclude with a theory of phantom limbs, some striking demonstrations of phantoms induced in normal subjects, and some remarks about the relevance of these phenomena to the question of how the brain constructs a 'body image.'. (shrink)

Patients with right parietal lesions often deny their paralysis , but do they have "tacit" knowledge of their paralysis? I devised three novel tests to explore this. First, the patients were given a choice between a bimanual task vs a unimanual one . They chose the former on 17 of 18 trials and, surprisingly, showed no frustration or learning despite repeated failed attempts. I conclude that they have no tacit knowledge of paralysis . Second, I used a "virtual reality box" (...) to convey the optical illusion to the patient that she was moving her paralyzed left hand up and down to the rhythm of a metronome, and yet she showed no sign of surprise. Third, I irrigated patient BM′s left ear canal with cold water, a procedure that is known to shift that patient′s spatial frame of reference by stimulating the vestibular system. Surprisingly, this allowed her "repressed" memory of paralysis to come to the surface; she said she had been paralyzed continuously for several days. I suggest that the vestibular stimulation produces these remarkable effects by mimicking REM sleep. These patients also emply a whole arsenal of grossly exaggerated Freudian "defense mechanisms" to account for their paralysis. To explain this, I propose that in normal individuals the left hemisphere ordinarily deals with small, local anomalies by trying to impose consistency but, when the anomaly exceeds threshold, an interaction with the right hemisphere forces a "paradigm shift". A failure of this process, in patients with right hemisphere damage, might partially account for anosognosia. Finally, I present a new conceptual framework that may help link several psychological and neurological phenomena such as Freudian defense mechanisms, vestibular stimulation, anosognosia, memory repression, visual illusions, anterograde amnesia, REM sleep, dreaming, and humor. (shrink)

Lewis’s [1968] counterpart theory (LCT for short), motivated by his modal realism, made its appearance within a year of Chisholm’s modal paradox [1967]. We are not modal realists, but we argue that a satisfactory resolution to the paradox calls for a counterpart-theoretic (CT-)semantics. We make our case by showing that the Chandler–Salmon strategy of denying the S4 axiom [◊◊ψ →◊ψ] is inadequate to resolve the paradox – we take on Salmon’s attempts to defend that strategy against objects from Lewis and (...) Williamson. We then consider three substantially different CT-approaches: Lewis’s LCT, Forbes’s (FCT), including his fuzzy version, and Ramachandran’s (RCT). We argue that the best approach is a mish-mash of FCT and RCT. (shrink)

Neurological syndromes in which consciousness seems to malfunction, such as temporal lobe epilepsy, visual scotomas, Charles Bonnet syndrome, and synesthesia offer valuable clues about the normal functions of consciousness and ‘qualia’. An investigation into these syndromes reveals, we argue, that qualia are different from other brain states in that they possess three functional characteristics, which we state in the form of ‘three laws of qualia’. First, they are irrevocable: I cannot simply decide to start seeing the sunset as green, or (...) feel pain as if it were an itch; second, qualia do not always produce the same behaviour: given a set of qualia, we can choose from a potentially infinite set of possible behaviours to execute; and third, qualia endure in short-term memory, as opposed to non-conscious brain states involved in the on-line guidance of behaviour in real time. We suggest that qualia have evolved these and other attributes because of their role in facilitating non-automatic, decision-based action. We also suggest that the apparent epistemic barrier to knowing what qualia another person is experiencing can be overcome by using a ‘bridge’ of neurons; and we offer a hypothesis about the relation between qualia and one's sense of self. (shrink)

On David Lewis's original analysis of causation, c causes e only if c is linked to e by a chain of distinct events such that each event in the chain (counter-factually) depends on the former one. But this requirement precludes the possibility of late pre-emptive causation, of causation by fragile events, and of indeterministic causation. Lewis proposes three different strategies for accommodating these three kinds of cases, but none of these turn out to be satisfactory. I offer a single analysis (...) of causation that resolves these problems in one go but which respects Lewis's initial insights. One distinctive feature of my account is that it accommodates indeterministic causation without resorting to probabilities. (shrink)

Subjects perceived touch sensations as arising from a table (or a rubber hand) when both the table (or the rubber hand) and their own real hand were repeatedly tapped and stroked in synchrony with the real hand hidden from view. If the table or rubber hand was then ‘injured’, subjects displayed a strong skin conductance response (SCR) even though nothing was done to the real hand. Sensations could even be projected to anatomically impossible locations. The illusion was much less vivid, (...) as indicated by subjective reports and SCR, if the real hand was simultaneously visible during stroking, or if the real hand was hidden but touched asynchronously. The fact that the illusion could be significantly diminished when the real hand was simultaneously visible suggests that the illusion and associated SCRs were due to perceptual assimilation of the table (or rubber hand) into one’s body image rather than associative conditioning. These experiments demonstrate the malleability of body image and the brain’s remarkable capacity for detecting statistical correlations in the sensory input. (shrink)

��Grapheme-color synaesthesia is a neurological phenomenon in which particular graphemes, such as the numeral 9, automatically induce the simultaneous perception of a particular color, such as the color red. To test whether the concurrent color sensations in graphemecolor synaesthesia are treated as meaningful stimuli, we recorded event-related brain potentials as 8 synaesthetes and 8 matched control subjects read sentences such as ‘‘Looking very clear, the lake was the most beautiful hue of 7.’’ In synaesthetes, but not control subjects, congruous graphemes, (...) compared with incongruous graphemes, elicited a more negative N1 component, a less positive P2 component, and a less negative N400 component. Thus, contextual congruity of synaesthetically induced colors altered the brain response to achromatic graphemes beginning 100 ms postonset, affecting pattern-recognition, perceptual, and meaning-integration processes. The results suggest that grapheme-color synaesthesia is automatic and perceptual in nature and also suggest that the connections between colors and numbers are bidirectional. (shrink)

First Published on: 21 June 2007 To cite this Article: Ramachandran, Vilayanur S., McGeoch, Paul D., Williams, Lisa and Arcilla, Gerard (2007) 'Rapid Relief of Thalamic Pain Syndrome Induced by Vestibular Caloric Stimulation', Neurocase, 13:3, 185 - 188 To link to this article: DOI: 10.1080/13554790701450446 URL: http://dx.doi.org/10.1080/13554790701450446..

Murali Ramachandran; V*—Methodological Reflections on Two Kripkean Strategies, Proceedings of the Aristotelian Society, Volume 95, Issue 1, 1 June 1995, Pages 6.

This article supplements our earlier paper on synaesthesia published in JCS (Ramachandran & Hubbard, 2001a). We discuss the phenomenology of synaesthesia in greater detail, raise several new questions that have emerged from recent studies, and suggest some tentative answers to these questions.

Unethical employee behavior (UEB), an important organizational phenomenon, is dynamic and multi-faceted. Recent renewed interest in the role of emotion in ethical decision-making (EDM) suggests that unethical behaviors are neither always rationally derived nor deliberately undertaken. This study explores how to integrate the conscious and nonconscious dimensions of unethical decision-making. By broadening the scope of inquiry, we explore how integral affect—the emotion tied to anticipated decision outcomes for the employee engaging in misconduct—can shed light on UEB. We review related literature (...) on affect and EDM and propose a model in which we assert that at a decision point, an employee experiences multiple integral affects that are either persuasive or dissuasive toward UEB. We further posit that among these integral affects, a dominant integral affect (DIA) emerges, determining the nature and direction of unethical behavior. In addition, our model considers the role of affective residue and the influence of other factors, such as incidental affect, disposition, context, and retrospection, to derive propositions. Our DIA model can help managers gain a comprehensive understanding of how affect, characterized by its locus (self or other orientation) and valence (enhancing or harming), determines the characteristics of UEB. (shrink)

Apotemnophilia, a disorder that blurs the distinction between neurology and psychiatry, is characterized by the intense and longstanding desire for amputation of a speci¢c limb. Here we present evidence from two individuals suggestive that this condition, long thought to be entirely psychological in origin, actually has a neurological basis. We found heightened skin conductance response..

"How can people come to believe that their poodle is an impostor? Or see colors in numbers? Francis Crick, co-discoverer of DNA, said of V. S. Ramachandran's first book, "The patients he describes are fascinating, and his experiments on them are both simple and ingenious." With his unique energy and style Ramachandran now shares his insights into the mind from such everyday human experiences as pain, sight, and the appreciation of beauty to the ultimate philosophical conundrums of consciousness."--BOOK (...) JACKET. (shrink)

We studied two otherwise normal, synaesthetic subjects who `saw' a speci¢c colour every time they saw a speci¢c number or letter. We conducted four experiments in order to show that this was a genuine perceptual experience rather than merely a memory association. (i)The synaesthetically induced colours could lead to perceptual grouping, even though the inducing numerals or letters did not. (ii)Synaesthetically induced colours were not experienced if the graphemes were presented peripherally. (iii)Roman numerals were ine¡ective: the actual number grapheme was (...) required. (iv)If two graphemes were alternated the induced colours were also seen in alternation. However, colours were no longer experienced if the graphemes were alternated at more than 4 Hz. We propose that grapheme colour synaesthesia arises from `cross-wiring' between the `colour centre' (area V4 or V8)and the `number area', both of which lie in the fusiform gyrus. We also suggest a similar explanation for the representation of metaphors in the brain: hence, the higher incidence of synaesthesia among artists and poets. (shrink)

The mechanism by which humans perceive others differs greatly from how humans perceive inanimate objects. Unlike inanimate objects, humans have the distinct property of being “like me” in the eyes of the observer. This allows us to use the same systems that process knowledge about self-performed actions, self-conceived thoughts, and self-experienced emotions to understand actions, thoughts, and emotions in others. The authors propose that internal simulation mechanisms, such as the mirror neuron system, are necessary for normal development of recognition, imitation, (...) theory of mind, empathy, and language. Additionally, the authors suggest that dysfunctional simulation mechanisms may underlie the social and communicative deficits seen in individuals with autism spectrum disorders. (shrink)

André Gallois’ (1993) modified account of restrictedly rigid designators (RRDs) does indeed block the objection I made to his original account (Gallois 1986; Ramachandran 1992). But, as I shall now show, there is a deeper problem with his approach which his modification does not shake off. The problem stems from the truth of the following compatibility claim: (CC) A term’s restrictedly rigidly designating (RR-designating) an object x is compatible with it designating an object y in a world W where (...) x exists but is distinct from y.1 It follows from (CC) that the necessary (contingent) truth of a sentence of the form “α is identical with β”, where “α” and “β” are RRDs of objects x and y respectively, does not require the necessary (contingent) identity of x and y. This is borne out by Gallois’ original example (see 1986, p. 58-63). Taking W to be the actual world, we have: (1) “Mary is identical with Mary” is necessarily true; yet “Mary” RR- designates Mary and Alice, which are only contingently identical. 1 I leave it to the reader to check that in Gallois’ own example (1986, p. 58), on the view he defends (pp. 62-63), and despite his modified characterisation of restricted rigidity, RDC# (1993, p. xx), “Mary” RR-designates Alice (as well as Mary) in W, but designates Mary and not A/ice in W1. Gallois has accepted this in correspondence. In light of (CC), while I agree with Gallois (1993, p. 153) that: (7) (a=b & ◊(a≠b)) → (∃x)(∃y)(x=y & ◊(x≠y)) is a theorem given RDC#, I dispute his defence of it (on p. 153). For, if (CC) is correct, the antecedent of (7) could be true even though a and b are identical in every world (where either exists)! (shrink)

In a recent article, Paul Noordhof (1999) has put forward an intriguing account of causation intended to work under the assumption of indeterminism. I am going to present four problems for the account, three which challenge the necessity of the conditions he specifies, and one which challenges their joint-sufficiency.

David Lewis modified his original theory of causation in response to the problem of ‘late preemption’ (see 1973b; 1986b: 193-212). However, as we will see, there is a crucial difference between genuine and preempted causes that Lewis must appeal to if his solution is to work. We argue that once this difference is recognized, an altogether better solution to the preemption problem presents itself.

A Russellian theory of (definite) descriptions takes an utterance of the form ‘The F is G' to express a purely general proposition that affirms the existence of a (contextually) unique F: there is exactly one F [which is C] and it is G. Strawson, by contrast, takes the utterer to presuppose in some sense that there is exactly one salient F, but this is not part of what is asserted; rather, when the presupposition is not met the utterance simply fails (...) to express a (true or false) proposition. A defender of Strawson's approach, however, must square up to what appear to be straightforward counterexamples to the presupposition thesis, and must also provide an account of certain linguistic phenomena that supposedly demand treating descriptions as quantifiers, as the Russellian theory does. In this paper I propose fresh considerations in favour of Strawson's approach. I shift attention from what the utterer presupposes to preconditions for the use of descriptions, and distinguish between referring and predicative uses of descriptions (not to be confused with referential and attributive uses); importantly, the referring and predicative uses have different preconditions, I argue, and these provide some satisfactory responses to the aforementioned challenges facing the Strawsonian. South African Journal of Philosophy Vol. 27 (3) 2008: pp. 242-257. (shrink)

Summary Transsexuals are individuals who identify as a member of the gender opposite to that which they are born. Many transsexuals report that they have always had a feeling of a mismatch between their inner gender-based ‘‘body image’’ and that of their body’s actual physical form. Often transsexuals undergo gender reassignment surgery to convert their bodies to the sex they feel they should have been born. The vivid sensation of still having a limb although it has been amputated, a phantom (...) limb, was first described by Weir Mitchell over a century ago. The same phenomenon is also occurs after amputation of the penis or a breast. Around 60% of men who have had to have their penis amputated for cancer will experience a phantom penis. It has recently been shown that a significant factor in these phantom sensations is ‘‘cross-activation’’ between the de-afferented cortex and surrounding areas. Despite this it also known that much of our body image is innately ‘‘hard-wired’’ into our brains; congenitally limbless patients can still experience phantom sensations. We hypothesise that, perhaps due to a dissociation during embryological development, the brains of transsexuals are ‘‘hard-wired’’ in manner, which is opposite to that of their biological sex. We go on to predict that male-to-female transsexuals will be much less likely to experience a phantom penis than a ‘‘normal’’ man who has had his penis amputated for another reason. The same will be true of female-to-male transsexuals who have had breast removal surgery. We also predict that some female-to-male transsexuals will have a phantom penis even although there is not one physically there. We believe that this is an easily testable hypothesis, which, if correct, would offer insights into both the basis of transsexuality and provide farther evidence that we have a gender specific body image, with a strong innate component that is ‘‘hard-wired’’ into our brains. This would furnish us with a better understanding the mechanism by which nature and nurture interact to link the brain-based internal body image with external sexual morphology.. (shrink)

In this paper we investigate three approaches to iterated contraction, namely: the Moderate (or Priority) contraction, the Natural (or Conservative) contraction, and the Lexicographic contraction. We characterise these three contraction functions using certain, arguably plausible, properties of an iterated contraction function. While we provide the characterisation of the first two contraction operations using rationality postulates of the standard variety for iterated contraction, we found doing the same for the Lexicographic contraction more challenging. We provide its characterisation using a variation of (...) Epistemic ranking function instead. (shrink)

Eukaryotic genomes are packaged into nucleosomal chromatin, and genomic activity requires the precise localization of transcription factors, histone modifications and nucleosomes. Classic work described the progressive reassembly and maturation of bulk chromatin behind replication forks. More recent proteomics has detailed the molecular machines that accompany the replicative polymerase to promote rapid histone deposition onto the newly replicated DNA. However, localized chromatin features are transiently obliterated by DNA replication every S phase of the cell cycle. Genomic strategies now observe the rebuilding (...) of locus‐specific chromatin features, and reveal surprising delays in transcription factor binding behind replication forks. This implies that transient chromatin disorganization during replication is a central juncture for targeted transcription factor binding within genomes. We propose that transient occlusion of regulatory elements by disorganized nucleosomes during chromatin maturation enforces specificity of factor binding. (shrink)

It is well known that Russell's theory of descriptions has difficulties with descriptions occurring within desire reports. I consider a flawed argument from such a case to the conclusion that descriptions have a referring use, some responses to this argument on behalf of the Russellian, and finally rejoinders to these responses which press the point home.