We invite systematic consideration of the metaphors of cycles and circulation as a long-term theme in the history of the life and environmental sciences and medicine. Ubiquitous in ancient religious and philosophical traditions, especially in representing the seasons and the motions of celestial bodies, circles once symbolized perfection. Over the centuries cyclic images in western medicine, natural philosophy, natural history and eventually biology gained independence from cosmology and theology and came to depend less on strictly circular forms. As potent ‘canonical (...) icons’, cycles also interacted with representations of linear and irreversible change, including arrows, arcs, scales, series and trees, as in theories of the Earth and of evolution. In modern times life cycles and reproductive cycles have often been held to characterize life, in some cases especially female life, while human efforts selectively to foster and disrupt these cycles have harnessed their productivity in medicine and agriculture. But strong cyclic metaphors have continued to link physiology and climatology, medicine and economics, and biology and manufacturing, notably through the relations between land, food and population. From the grand nineteenth-century transformations of matter to systems ecology, the circulation of molecules through organic and inorganic compartments has posed the problem of maintaining identity in the face of flux and highlights the seductive ability of cyclic schemes to imply closure where no original state was in fact restored. More concerted attention to cycles and circulation will enrich analyses of the power of metaphors to naturalize understandings of life and their shaping by practical interests and political imaginations. (shrink)

Samenvatting van de grote wijsgerige systemen van Plato tot en met Hegel, gevolgd door een kritische analyse van de metafysica als uitingsvorm van westers intellectualisme.

The European Commission’s proposal to address antimicrobial resistance using transferable exclusivity vouchers (TEVs) is fundamentally flawed. European policymakers and regulators should consider alternatives, such as better funding for basic and clinical research, use of advance market commitments funded by a pay-or-play tax, or enacting an EU Fund for Antibiotic Development.

This article explores the concept of divine revelation as presented by Blaise Pascal, examining the fundamental dichotomy between the hidden and revealed aspects of God. Beginning with the premise of human existence as inherently obscure and lost in the universe without apparent reason, the study delves into Pascal’s inquiry into the origins of human existence and the role of God as both a part of and apart from this primordial darkness. Pascal’s reflections on the incomprehensibility of man before that of (...) God highlight a foundational obscurity, setting the stage for a deeper investigation into the nature of divine revelation. The article contrasts Pascal’s perspective with traditional theological and philosophical views, particularly in relation to the manifest nature of God as commonly interpreted through natural phenomena. It further delves into Pascal’s interpretation of scriptural passages, notably Isaiah 45:15, emphasizing the notion of Deus Absconditus (Hidden God) and its critical role in understanding the paradoxical nature of divine revelation. The article examines how Pascal perceives God’s manifestation through various historical and mystical dimensions, including nature, the Incarnation, and the Eucharist, each revealing God while simultaneously concealing Him. (shrink)

Every reader of Ricoeur knows that hermeneutics endeavors to answer the aporiae of historical phenomenology. Hence arises the need to return to those aporiae and those answers. On the one hand, phenomenology, born with the maxim of going “directly to things themselves,” is confronted with the incessant evasion of the thing itself and with its dreams of presence being thereby shattered. This reversal should not be blamed on the failings of this or that thinker, but attributed to the very destiny (...) of phenomenology itself. On the other hand, Ricoeurian hermeneutics takes note of a gap, and of a necessary return. Thus, there is nothing for thought itself to grieve over with respect to this enterprise. However, while the phenomenology of Merleau-Ponty, faced with the same difficulties, orients itself towards political philosophy, the hermeneutics of Ricoeur rather seeks to lead us to a philosophy of religion. This article hypothesizes that, in spite of the formula of a “philosophy without an absolute,” the thought of Ricoeur heads in fair measure towards the Absolute, and that ontology is not the only name of the Promised Land. (shrink)

This article considers the childrens writer Alison Uttley, and, particularly, her engagements with debates regarding science and philosophy. Uttley is a well-known childrens author, most famous for writing the Little Grey Rabbit series, but very little critical attention has been paid to her. She is also an important alumna of the University of Manchester, the second woman to graduate in Physics. In particular, the article looks at her novel A Traveller in Time through the lens of her thinking on time, (...) ethics, history and science. The article draws on manuscripts in the collection of the John Rylands Library to argue that Uttley‘s version of history and time-travel was deeply indebted to her scientific education and her friendship with the Australian philosopher Samuel Alexander. (shrink)

This article challenges Nicholas Wolterstorff’s rights-based reading of Old Testament orphans by arguing that the prophetic demand for their cause not only assumes a right-order ethos championed in the Torah, but in doing so exposes the shortcomings in how justice is defined for orphaned children within current rights ideology, whether theistic or not. I present the orphan’s historical trajectory towards becoming socially vulnerable as the final stage in the transition from the kinship-redeemer justice of Israelite village clans to the chesed (...) justice of the patronage economy in emerging urban conditions. In light of these conditions, I show how the orphan laws in Deuteronomy are, counter to Wolterstorff’s claims of corruption, attempting to re-create in legal terms the kinship bond and chesed benevolence that defines the orphan’s justice as the return to a family. I argue that the prophet does not blame inherently corrupt laws, but rather blames patrons and elders who have ignored good laws and ignored right-order by forgetting their brothers’ and sons’ children. (shrink)

In this article, the French philosopher Jérôme de Gramont evaluates the modes in which twentieth century philosophy and literature—from Heidegger and Derrida to Blanchot and Beckett—aim to think our being-in-the-world beyond the concept of “man” and without the genus of the human.

This paper reviews the work on gendered achievement in the English?speaking Caribbean, with its often explicit focus on underachieving males. However, patterns of gendered achievement are more likely region?specific and variegated in some contexts. In Trinidad and Tobago, the full?scale implementation of national assessments in 2004 provided an opportunity to evaluate mathematics and language performance across the entire pupil population at standards 1 (7? to 8?year?olds) and 3 (9? to 10?year?olds). Census data from the high?stakes 2003 Secondary Entrance Assessment (SEA) (...) administered at standard 5 (ages: 10?11+) were also included in the analysis. Therefore the entire dataset consisted of 52,284 primary school students (26,574 males and 25,710 females). The findings confirmed that female pupils had a statistically significant advantage on all assessments. However, in terms of practical significance, most differentials were negligible to small. Medium?sized differentials were obtained for pupils of low ability, living in rural educational districts, and on language arts. Male achievement scores were also more variable for lower grade levels, low ability groups and language arts. Paradoxically, in some educational districts secondary school placement opportunities still favoured males. These variegated patterns of gendered achievement may be associated with differences in institutional effectiveness and variations in male socialization practices that are especially evident across the urban?rural divide. (shrink)

In this review, we provide an overview of the dynamic changes within the microbiota and its metabolites that are implicated in establishing and maintaining gastrointestinal homeostasis during various stages of microbial colonization. The gradual conversion of the gut microbiota toward a mutualistic microbial community involves replacement of pioneer gut colonizers with bacterial taxa that are characteristic for the adult gut. An important microbial signature of homeostasis in the adult gut is the prevalence and activity of a diverse spectrum of bacterial (...) species that produce beneficial metabolites through metabolic interactions between microbial groups. Deciphering these microbial signatures and their metabolites that govern short and long‐term equilibrium, as well as imbalances in host‐microbial relationships, may provide novel diagnostic tools and/or therapeutic targets for specific disorders associated with intestinal dysbiosis and loss of homeostasis. (shrink)

C’est en philosophe que Jan Patočka entreprend de répondre à la crise de l’Europe et aux désastres de l’histoire auxquels il est confronté, en revenant à la naissance de la philosophie, non pas dans un simple souci d’histoire, mais en vue d’un nouveau commencement. Il s’appuiera pour cela sur Platon (« Le platonisme négatif », Platon et l’Europe) puis sur les présocratiques (notamment sur Héraclite, dans ses Essais hérétiques sur la philosophie de l’histoire). C’est alors qu’il peut montrer comment la (...) crise s’inscrit dans la physis et pas seulement dans l’histoire, mais aussi comment, dans l’histoire, des hommes peuvent se dresser pour atteindre un « plus-haut ». (shrink)

Au commencement de la vie religieuse, il pourrait y avoir un verbe humain fait de plus de doute que de savoir, de plus d’inévidence que d’évidence. Deux vers du poète Jules Supervielle portent jusqu’à une expression claire cette expérience encore obscure : Voilà que je me surprends à t’adresser la parole, Mon Dieu, moi qui ne sais encore si tu existes. Ces deux vers constituent l’incipit d’un poème intitulé « Prière à l’inconnu » publié dans le recueil La Fable du (...) monde, et sont cités surtout... (shrink)

En 1972, Emmanuel Levinas ouvre l’article qu’il consacre à Paul Celan par une citation justement célèbre : « Je ne vois pas de différence entre une poignée de mains et un poème ». Ce que voit Paul Celan dans une poignée de mains mériterait assurément de longs commentaires, ce qu’entend Emmanuel Levinas dans ce poème élémentaire est et n’est pas plus simple. D’une certaine manière, la poignée de mains ne dit rien mais elle dit : simple signe lancé à l’autre, (...) elle se résume dans un dire sans di... (shrink)

We often feel that our perceptual experience is richer than what we can express. For instance, when flashed with a large set of letters, we feel that we can see them all, while we can report only a few. However, the nature of this subjective impression remains highly debated: while many favour a dissociation between two forms of consciousness , others contend that the richness of phenomenal experience is a mere illusion. Here we addressed this question with a classical partial-report (...) paradigm now modified to include unexpected items in the unreported parts of the stimuli. We show that even in the presence of unexpected pseudo-letters, participants still felt that there were only letters. Additionally, we show that this feeling reflects an illusion whereby participants reconstruct letters using partial letter-like information. We propose that the feeling of seeing emerges from the interplay between partially accessible information and expectations. (shrink)

This article discusses the moment in which normative ideas about aging and reproductive embodiment became conceptually linked in the mid-nineteenthcentury medicalization of menopause. The reading centers on the first English book-length publication on menopause, written by E. J. Tilt in 1857, and Foucault’s concept of the medical gaze. I analyze mechanisms of observing, conceptualizing, and treating the body in relation to time and discuss their function in affirming and reworking social norms of age and gender. In doing so, I highlight (...) the political work implicit in contesting conceptualizations of female reproductive bodies, their age-specific pathologies, and directives of surveillance employed in discourses surrounding women’s reproductive health. (shrink)

"De Charles S. Peirce, logicien et philosophe américain (1839-1914), on sait généralement qu'il a élaboré une théorie du signe, voire qu'il est le fondateur du pragmatisme. Ce que l'on sait moins, c'est qu'il est le premier à avoir développé une conception de l'information dans le cadre de ses recherches sur la philosophie de la science. Ce livre est l'étude des fondements logiques et sémiotiques de cette conception. Il se concentre sur les années 1865-1867, durant lesquelles Peirce définit les parties principales (...) de son système philosophique et montre que la notion d'information est un élément essentiel de ce système. La question que pose Peirce est de savoir comment et dans quelle mesure les représentations sont capables d'augmenter la quantité de ce qu'elles représentent. Il découvre qu'elles peuvent le faire de deux manières, selon qu'elles participent de l'un ou l'autre des deux types d'inférences probables que sont l'induction et l'abduction. L'information est la mesure de cette croissance de la connaissance au coeur des représentations. La notion d'information s'inscrit dans le type de réalisme qui définit la première période de la philosophie de Peirce. Elle est aussi un élément précurseur de ce qu'il appellera plus tard sa "logique du vague"."--Page 4 of cover. (shrink)

L’homme est un animal extraordinaire selon Platon, mais il est bien un animal. Il faut donc maîtriser et domestiquer l’animalité de l’homme. Le cas de l’alimentation montre l’importance des pulsions animales en l’homme. L’animal n’est pas l’autre de l’homme, mais l’une de ses possibilités.