The paper is aimed at rationalizing relationships between the structure of inorganic compounds in condensed phases and their melting and boiling points. It is documented that the main factor governing both points is their molecular or polymeric nature. In case of polymeric ionic compounds, the higher actual charge bearing by the ions involved, the higher their melting/boiling points. In case of covalent polymers, the value of both points increases with polymer dimensionality and with the number and energy of (...) the respective covalent bonds. In case of molecular compounds, both points depend on the weight and shape of molecules, the presence of hydrogen bonds, and electric quadrupole moment. (shrink)

In contrast to anti-Jewish campaigns at German universities in the 19th century, which met with opposition from liberal scholars, among them prominent chemists, there was no public reaction to the dismissals in 1933. Germany had been an international leader in chemistry until the 1930s. Due to a high proportion of Jewish physicists, chemistry was strongly affected by the expulsion of scientists. Organic and inorganic chemistry were least affected, while biochemistry suffered most. Polymer chemistry and quantum chemistry, of minor importance (...) among the majority of academic chemists was further weakened by the expulsion of renowned scientists. However, a look at the research carried out in Nazi Germany shows that no field of research "emigrated" as such, except research into molecular beams. The reception of emigré chemists differed with respect to their field of research and the degree of competition in the host countries. Thus biochemists and physical chemists were accepted at American universities, whereas organic chemists were not. In contrast, they received high positions in Turkey, Palestine/Israel, and Egypt. After WWII, few emigrés were asked to come back. The delay of the resumption of international contacts by German chemists contributed to the delay in rebuilding in particular German biochemistry, the physical chemistry of polymers, and physical organic chemistry. (shrink)

DNA and RNA are the only known natural genetic materials. Systematic modification of each of their chemical building blocks (nucleobase, sugar, and phosphate) has enabled the study of the key properties that make those nucleic acids genetic materials. All three moieties contribute to replication and, significantly, all three moieties can be replaced by synthetic analogs without loss of function. Synthetic nucleic acid polymers capable of storing and propagating information not only expand the central dogma, but also highlight that DNA (...) and RNA are not unique chemical solutions for genetic information storage. By considering replication as a question of information transfer, we propose that any polymer that can be replicated could serve as a genetic material.Editor's suggested further reading in BioEssays Xenobiology: A new form of life as the ultimate biosafety tool Abstract. (shrink)

Aristotle’s Meteorology 4.12 is puzzling, in part because the chapter appears to extend teleological explanation to include certain inorganic materials without natural biological functions, such as metals and stone. This paper examines two attempts to explain why such materials can have functions, and shows that they are problematic. As an alternative, I argue that raw inorganic materials—as well as separated parts of organisms—can have extrinsic functions. Extrinsic functions can explain why natural inorganic materials can be sorted into (...) natural kinds, even if their functions are ultimately related to their uses in the productive arts. (shrink)

In explicating his version of the Organism View, Eric Olson argues that you begin to exist only after twinning is no longer possible and that you cannot survive a process of inorganic replacement. Assuming the correctness of the Organism View, but pace Olson, I argue in this paper that the Organism View does not require that you believe either proposition. The claim I shall make about twinning helps to advance a debate that currently divides defenders of the Organism View, (...) while the claim I shall make about inorganic replacement will help to put the Organism View on a par with its rival views by allowing it to accommodate a plausible intuition that its rivals can accommodate, namely, the intuition that you can survive a process of inorganic replacement. Both claims, I shall also argue, are important for those who are interested in the identity condition of a human organism, even if they do not hold the view that you are essentially an organism. (shrink)

Hydroxycamptothecin is a potent antineoplastic agent that has shown efficacy against multiple tumor lines in vitro. eww140918dxn This is the first study to investigate the release, distribution, and efficacy of hydroxycamptothecin which was incorporated into the biodegradable polymer Polylactic Acid (PLA), and implant into brain directly. In vitro release curve generated showed that a large initial release occurred over the first three days and was followed by a steady, but considerably slower rate of release over the next 25 days. After (...) implanting the discs into 40 male SD rats, the animals were followed up to 28 days, where the concentration in brain tissue was far higher than that in peripheral blood at the each of the eight time-points evaluated, and it was also within the therapeutic range for C6 cells tested in vitro. The in vivoefficacy of the discs was evaluated with rats inoculated intracranially with C6 glioma and treated with hydroxycamptothecin polymer compared to intravenous as well as intratumoral injections; the median survival is 21.1, 13.9, 14.9 days, respectively. Given these data, we conclude that the biodegradable polymer PLA releases hydroxycamptothecin, producing tumoricidal levels in brain tissues and prolonging survival in a rat glioma model. (shrink)

We give an elementary introduction to non-standard analysis and its applications to the theory of stochastic processes. This is based on a joint book with J. E. Fenstad, R. Høegh-Krohn and T. Lindstrøm. In particular we give a discussion of an hyperfinite theory of Dirichlet forms with applications to the study of the Hamiltonian for a quantum mechanical particle in the potential created by a polymer. We also discuss new results on the existence of attractive polymer measures in dimension d (...) ≤ 5, with applications to the (φ 1 2 φ 2 2 )d-mode1 of interacting quantum fields. (shrink)

What separates Mario Perniola from other philosophers of his generation, is his programmatic inquiry into the dark side of humanities, what I here call ‘dank humanities’ – with a focus on topics hard to catch, and sides of experience and interpretation which evade simple pleasure and order. Often his thinking finds a niche where one can feel barely human or sense something that in the end evades interpretation. Suggestive in tone, it inquired into these topics also in a way that (...) made his thinking hard to classify as philosophy, cultural studies and/or psychoanalysis. In my article on his work, I aspire to think of it more commonly as a form of overall humanities, and to see it as a programmatic attempt to nail the potentials of the humanities to reach beyond our pleasures, understanding and safety-driven metaphysics. (shrink)

If literary avant-garde journals and their communities have been, in the twentieth century, a space for creating, if not sustaining, major political utopias, it should help explain why this “literary communism,” as Jean-Luc Nancy called it, is not a weakened or substitutional form of politics. No myth without narration, no implementation without an instrumentation, no organic unity without a political organ voicing its claim, in short: no organicity without an organon. But can there be a (literary) community that does not (...) aim at the achievement of its own assumed truth, a form of writing in common that does not serve to convey a meaning, but bears witness, in its very form, to the fragmentation of meaning? This essay examines three attempts of an affi rmative answer to this question by reappraising three interrelated experimental cases: Jena around 1800 and the Athenaeum journal of the Early Romantics; Walter Benjamin’s journal projects, from the Angelus Novus to the prison camp journal at the end of his life; Maurice Blanchot and the failed trans-European project of what was arguably the most ambitious intellectual journal enterprise of the century, the Revue internationale in the early 1960s. (shrink)

Systems theory provides a surprisingly fruitful approach to several important ideas held in common by Paul Tillich and Pierre Teilhard de Chardin. These include complexity or organization as the key to understanding the distinction between the inorganic and the organic, and hierarchy or levels in complex systems. Teilhard and systems theorists accept hierarchy as fundamental. Tillich questions the concept and prefers “dimensions,” including the inorganic, organic, psychological, spiritual, and historical dimensions. Tillich's rejection of hierarchy is questioned, but significant (...) correlations are discovered in the systems interpretation of the psychological and spiritual dimensions as well as in the use of “centeredness” by both thinkers. (shrink)

Doubled lives -- Autobiography -- Automatic life, so life: Descartes -- Order catastrophically unknown: Freud -- The blushing machine: Derrida -- Translation -- The point if at all: Cixous and Celan -- Naming the mechanical angel: Benjamin -- Raw war: Schmitt, Jønger, and Joyce -- Resonance -- Bloodless coup: Bataille, Nancy, and Barthes -- The audible life of the image: Godard -- Meditations for the birds: Descartes.

This paper explores the concept of "inorganic sexuality" in the work of Italian writer and philosopher Mario Perniola. The main objective is to develop the controversial and original aspects of Perniola's thought within his aesthetic theory of feeling. Perniola elaborates the so-called "thing that feels", namely a feeling in which the neutral and impersonal dimensions of the things flow into organic life and vice versa. This perspective, as will be clarified, by dissolving the vitalist and spiritualist drives of the (...) subject, enlarges the horizon of aesthetic feeling by welcoming what is commonly left outside of it: the inorganic and material world, in its surprising aspects, but also in its uncanny and disturbing ones. Therefore, the main goal of this paper is to show the significance and the value of neutral sexuality, which opens up a space of experiences beyond the traditional metaphysical oppositions such as masculine/feminine, organic/inorganic, alive/dead, real/virtual, gender/sex. (shrink)

This is a translation of part of Fr. Hoenen’s Cosmologia in which the author sets out, so the translator tells us in the preface, to discover the philosophical explanation of non-living or inorganic compounds. One wonders why he decided to equate non-living with inorganic and to omit a number of organic compounds which are also non-living. The book makes heavy reading for the English is prolix, awkward and jejune. One gets the impression too that the translator is not (...) exactly at home in the field of chemistry. When quoting chemical laws it would have been better to employ some standard formula which would have avoided such clumsy statements as the following: ‘Given gases at a constant temperature and pressure, the volumes of the component gases taking part in a reaction are in simple proportion to one another and to the volume of the chemical compound’. Again on p. 36 we find: ‘The Molecular theory, in so far as it is now confirmed, may be stated thus: Gaseous bodies consist of molecules as of parts actually discrete’. (shrink)

The theoretical principles and methodological aspects of the thermal field-flow fractionation applied to study the thermal diffusion of the macromolecules in solution and colloidal particles in suspension were developed. The theoretical analysis indicated that the miniaturization of the separation channel for thermal field-flow fractionation should improve the performance of this technique. A new microchannel was conceived and built. The experimental results obtained for polymer samples with an extended range of molar masses from relatively low up to ultrahigh and for the (...) colloidal particles confirmed that the achieved resolution is the same but the versatility of the microchannel is superior to that of the standard size channels owing to the substantial decrease in the heat energy flux. This important improvement allows us to achieve very high resolution when applying constant-field-force operation, it makes it much easier to program the temperature drop which is an advantageous operational mode from the viewpoint of the time of analysis, and it extends considerably the range of perfectly controlled temperatures of the cold and hot walls. The sample amount needed for one analysis can be as small as a few nanograms. (shrink)

Many of the earliest books, particularly those dating back to the 1900s and before, are now extremely scarce and increasingly expensive. We are republishing these classic works in affordable, high quality, modern editions, using the original text and artwork.

Until recently philosophy of physics has been overshadowed by the idea that the important philosophical issues that can be derived from physics are related only to fundamental theories, such as quantum mechanics and relativity. Applied fields of physics were deemed as unimportant. The argument for such a position lays in thinking that these applied fields of physics depend in their theoretical representations on fundamental theories and hence are reducible to these fundamental theories. It would be hard to defend such a (...) position, keeping in mind that applied fields of physics have a life of its own totally separate from fundamental physics and have in fact a lot to say to philosophers. The field of polymers is one of the branches of applied physics that has a lot to say to philosophers. It is a field of physics where theoreticians failed to present a coherent theory that can capture the different ways polymers can be built. This paper examines the difficulties that keep theoreticians away from having such a theory, revealing what kind of philosophical lessons polymers might have. The main thesis is: even in the cases where a theory predict the possibility of developing a specific type of polymers that was not previously known, the exact model that represent the outcome polymer theoretically will not be even in principle derivable from the theory that predicted its existence in the first place. (shrink)

Abstract:This article discusses Hegel's claim that nature is the idea (Idee) having become external (äußerlich) to itself. Usually taken to signal a type of limitation in Hegel's philosophy, the author argues that recent interpretations of nature's externality are not entirely successfully because they reconstruct nature by either looking back to logic or forward to spirit. Instead, the article offers an interpretation that starts off from Hegel's argument that nature is "weak" (ohnmächtig) as it is not, nor can become, thoroughly rational. (...) It then traces the implications of this view in Hegel's inorganic philosophy of mechanics and physics. There, in a discussion that culminates with matter as fundamentally "brittle," a picture of externality emerges as the likelihood in nature of "deformed" or "damaged" determinations. What is ultimately unique about nature vis-à-vis logic is a setting in which partial rational determination makes sense at all. (shrink)