Abstract
Descartes's greatest glory was to be the first to articulate, and systematically to defend, the new scientific ideal of explanation in terms of lawfulness. For the realm of matter, lawful connections replaced anthropomorphic volitions as the model of rational explanation. Descartes's use of explanation in terms of lawfulness, inspired by Galileo's beginnings in this enterprise, was vindicated by Newton's subsequent achievement. Replacement of anthropomorphic agency, by causal mechanism, as the explanatory model, was undoubtedly the most profound of the many effects of the new science on our culture