In 1981, David Hubel and Torsten Wiesel received the Nobel Prize for their research on cortical columns—vertical bands of neurons with similar functional properties. This success led to the view that “cortical column” refers to the basic building block of the mammalian neocortex. Since the 1990s, however, critics questioned this building block picture of “cortical column” and debated whether this concept is useless and should be replaced with successor concepts. This paper inquires which experimental results after 1981 challenged (...) the building block picture and whether these challenges warrant the elimination “cortical column” from neuroscientific discourse. I argue that the proliferation of experimental techniques led to a patchwork of locally adapted uses of the column concept. Each use refers to a different kind of cortical structure, rather than a neocortical building block. Once we acknowledge this diverse-kinds picture of “cortical column”, the elimination of column concept becomes unnecessary. Rather, I suggest that “cortical column” has reached conceptual retirement: although it cannot be used to identify a neocortical building block, column research is still useful as a guide and cautionary tale for ongoing research. At the same time, neuroscientists should search for alternative concepts when studying the functional architecture of the neocortex. keywords: Cortical column, conceptual development, history of neuroscience, patchwork, eliminativism, conceptual retirement. (shrink)

Microbial diversity has become a leitmotiv of contemporary microbiology, as epitomized in the concept of the microbiome, with significant consequences for the classification of microbes. In this paper, I contrast microbiology’s current diversity ideal with its influential predecessor in the twentieth century, that of purity, as epitomized in Robert Koch’s bacteriological culture methods. Purity and diversity, the two polar opposites with regard to making sense of the microbial world, have been operationalized in microbiological practice by tools such as the “clean” (...) Petri dish versus the “dirty” Winogradsky column, the latter a container that mimics, in the laboratory, the natural environment that teems with diverse microbial life. By tracing the impact of the practices and concepts of purity and diversity on microbial classification through a history of techniques, tools, and manuals, I show the shifts in these concepts over the last century. Juxtaposing the dominant purity ideal with the more restricted, but continuously articulated, diversity ideal in microbial ecology not only provides a fresh perspective on microbial classification that goes beyond its intellectual history, but also contextualizes the present focus on diversity. By covering the period of a century, this paper outlines a revised longue durée historiography that takes its inspiration from artifacts, such as Petri dish and the Winogradsky column, and thereby simple, but influential technologies that often remain invisible. This enables the problem of historical continuity in modern science to be addressed and the accelerationist narratives of its development to be countered. (shrink)

In the De Pythiae oraculis (397e) Plutarch mentions, according to the manuscript tradition, a bronze column of Hiero I of Syracuse, which stood in the sanctuary of Delphi and fell down on the day of his death. After retracing the interpretations of this passage both in the philological and archaeological studies and pointing out their problematic aspects, the author proposes a new reading of the text, suggesting that the monument involved was a statue of Hiero I instead of a (...) column. (shrink)

The concept of the cortical column refers to vertical cell bands with similar response properties, which were initially observed by Vernon Mountcastle’s mapping of single cell recordings in the cat somatic cortex. It has subsequently guided over 50 years of neuroscientific research, in which fundamental questions about the modularity of the cortex and basic principles of sensory information processing were empirically investigated. Nevertheless, the status of the column remains controversial today, as skeptical commentators proclaim that the vertical cell (...) bands are a functionally insignificant by-product of ontogenetic development. This paper inquires how the column came to be viewed as an elementary unit of the cortex from Mountcastle’s discovery in 1955 until David Hubel and Torsten Wiesel’s reception of the Nobel Prize in 1981. I first argue that Mountcastle’s vertical electrode recordings served as criteria for applying the column concept to electrophysiological data. In contrast to previous authors, I claim that this move from electrophysiological data to the phenomenon of columnar responses was concept-laden, but not theory-laden. In the second part of the paper, I argue that Mountcastle’s criteria provided Hubel Wiesel with a conceptual outlook, i.e. it allowed them to anticipate columnar patterns in the cat and macaque visual cortex. I argue that in the late 1970s, this outlook only briefly took a form that one could call a ‘theory’ of the cerebral cortex, before new experimental techniques started to diversify column research. I end by showing how this account of early column research fits into a larger project that follows the conceptual development of the column into the present. (shrink)

Parapsychologists have never been entirely satisfied with their technical vo- cabulary, and occasionally their discontent leads to attempts at terminological reform.1 Recently, a number of prominent parapsychologists, led by Ed May, have regularly abandoned some of parapsychology’s traditional and central categories in favor of some novel alternatives (see, e.g., May, Utts, and Spot- tiswoode, 1995a, 1995b; May, Spottiswood, Utts, and James, 1995). They rec- ommend replacing the term ª ESPº with ª anomalous cognitionº (or AC) and ª psychokinesis (PK)º with (...) ª anomalous perturbationº (or AP). Advocates of these new terms also propose replacing the term ª psiº or ª psi phenomenaº with ª anomalous mental phenomena.º Superf icially at least, these proposals seem merely to be modest extensions of parapsychology’s increasingly fre- quent use of the term ª anomalousº as a substitute for ª paranormal,º a practice which (although controversial) is not without merit, and which Palmer has vigorously defended (1986, 1987, 1992). But in my view, the proposed new terminology creates more problems than it solves. (shrink)

Design problems in structural engineering are often modeled as differential equations. These problems are posed as initial or boundary value problems with several possible variations in structural designs. In this paper, we have derived a mathematical model that represents different structures of beam-columns by varying axial load with or without internal forces including bending rigidity. We have also developed a novel solver, the LeNN-NM algorithm, which consists of weighted Legendre polynomials, and a single path following optimizer, the Nelder–Mead algorithm. To (...) evaluate the performance of our solver, we have considered three design problems representing beam-columns. The values of performance indicators, MAD, TIC, NSE, and ENSE, are calculated for a hundred simulations. The outcome of our statistical analysis points to the superiority of the LeNN-NM algorithm. Graphical illustrations are presented to further elaborate on our claims. (shrink)

This article discusses some of the philosophical themes in the Hollywood film "The Truman Show." I argue that the film presents and interesting twist on the traditional philosophical problem of skepticism. Whereas Descartes' skeptical worries were based on the deceptive nature of sense perception, the source of illusion and skepticism in the Truman Show is the modern media system and "reality TV." This engaging film compels viewers to reflect upon the extent to which we are all ensnared in a world (...) of lies and deceit. (shrink)

La date de l'installation des croix dans les colonnes et les murs de l'Eglise Sainte-Sophie est difficile à connaître. D'après leurs formes, il s'agirait d'un phénomène post-iconoclaste, qui se situerait entre le 10e et le 12e siècles. Ces croix étaient très certainement des reliques témoignant d'un phénomène de piété populaire dans l'Eglise centrale de l'Empire byzantin. Un appendice donne une description de ces croix, un plan de l'Eglise Sainte-Sophie ainsi que la reproduction de onze photographies.

This is the second volume, following the well-received edition of Mill's writing essential to understanding the liberal tradition. His commentary on a full spectrum of issues gives further insight into the strengths and vulnerabilities of liberal democratic theory in practice. Rare and difficult to locate material is here brought to attention and made available. The contribution of Mill's most authoritative biographer, Nicholas Capaldi, is a singular and unmatched highlight. The tenor of St. Augustine's Press volumed on Mill is distinct in (...) its intention to place his work in the framework of political philosophy and the conversation of the viability of liberalism as a tradition of thought. (shrink)

The most discussed and mysterious column within the Babylonian astronomy is columnΦ. It is closely connected to the lunar velocity and to the duration of the Saros. This paper presents new ideas for the development and interpretation of columnΦ. It combines the excellent Goal-Year method with old ideas and practices from the “schematic astronomy”. Inspired by the old “TU11” rule for prediction of times of lunar eclipses, it proposes that columnΦ, in a similar way, used the sum of the (...) Lunar Four to predict times of lunar eclipses as well as the duration of one, 6, and 12 months by means of what usually is called “R–S” schemes. It also explains fully the structure and development of such schemes, a fact that strongly supports the new interpretation of columnΦ. (shrink)

Curt Verschoor on Ethics is a compilation of the best business ethics columns that will continue for years forward to be of lasting educational value. In a company setting, the columns can function as the basis for discussion on proper business ethics. In academia, the columns can serve as assigned readings over significant ethics events and issues. Some topics that are covered in the columns include: value of a strong ethical culture, studies of ethical and unethical culture, public and management (...) accounting ethics, ethics of executive compensation, international ethics standards, fraud case studies, small organization fraud studies, regulation and enforcement, whistleblowing, sustainability and integrated reporting, tax avoidance issues, students. (shrink)

Despite the growing research and theoretical formulations tied to memory storage within the brain, the role of cortical columns has received relatively little attention. The current paper presents a theoretical formulation based on cortical columns as the binary units that contain all cortical information, and how memory and learning may occur based on the interaction patterns of columns. The described model is an extension of Lurian views, and suggests higher functions to result from the interaction of five systems. Specific mechanisms (...) by which the thalamus and cortex interact to create long term memory formation are delineated. There is the suggestion of two distinct, but interactive, sensory–cortical memory systems, one for factual/generic memories and the other for episodic/personal memories. Hemispheric lateralization of function is explained on the basis of speed and quantity of columnar activation. Conclusions focus on recent technological advances that may allow cortical models to be testable in the near future. (shrink)

No writer or public intellectual of our era has been as sensitive to the role of faith in the lives of ordinary Americans as Robert Coles. Though not religious in the conventional sense, Coles is unparalleled in his astute understanding and respect for the relationship between secular life and sacredness, which cuts across his large body of work. Drawing inspiration from figures like Dietrich Bonhoeffer, Dorothy Day, and Simone Weil, Coles’s extensive writings explore the tug of war between faith and (...) doubt. As Coles himself admits, the “back-and-forthness between faith and doubt is the story of my life.” These thirty-one thought-provoking essays are drawn from Coles’s weekly column in the Catholic publication _America_. In them, he turns his inquisitive lens on a range of subjects and issues, from writers and painters to his recent reading and film viewing, contemporary events and lingering controversies, recollections of past and present mentors, events of his own daily life, and ordinary encounters with students, patients, neighbors, and friends. Addressing moral questions openly and honestly with a rare combination of rectitude and authorial modesty, these essays position Coles as a preeminent, durable, and trusted voice in the continuing national conversation over religion, civic life, and moral purpose. (shrink)

Information about celebrities is abundant in media, including bits of information about marginal events that appear in gossip columns; a media genre not sufficiently studied. This article analyzes Israeli national gossip columns in an attempt to identify stylistic and linguistic ways columnists frame information as confidential and personal. It is argued that the use of discursive strategies creates an illusion of intimacy between the reader and the column, inviting readers to participate in a deciphering game. Columnists engage readers by (...) creative use of pronouns, reported speech, use of coda and lexical inventions intended to criticize and poke fun at celebrities. The analysis traces the origins of this specific discourse in Israeli modes of communication. (shrink)

In 2003, Peratt demonstrated that rock art images worldwide bear a remarkable similarity to high-energy plasma discharge formations. In later papers, Peratt located the plasma discharge column in which all of these would have occurred at the Earth’s South Pole. This article accepts the relation between the rock art images and the plasma formations, but concludes that the geometry of the reconstruction is incompatible with the global occurrence of the rock art images. As a corollary, the finer details of (...) the reconstructed column must also be called into question. In particular, the reconstruction of the top cusp, the two upper plasmoids, and the filamentary sheath in a single column at the South Pole cannot be reliably deduced from the data as presented by Peratt. All evidence points to a worldwide distribution of the phenomena. (shrink)