Emphasizing the relevance of celibate singleness for the French women's movement, Ly affirmed that "more and more, we will recruit the elite of our adepts and militants from these noble freethinkers, these inspiring rebels" who were not legally "under their husbands' authority" or otherwise restricted by familial obligations.1 Given the early twentieth-century context of heightened national fears about France's flagging birth rate and the degeneration of the French "race," Ly's argument for political spinsterhood hardly encountered a popular reception, either within (...) liberal or feminist circles. Citing passionate fears of female political activism and the New Woman against an anxious background of nationalistic and conservative revival, scholars have underscored the French movement's need to present a nonviolent and "feminine" image to the public, one that did not openly challenge women's primary sexual, marital, or reproductive roles.5 Historian Karen Offen has most notably argued that the majority of feminists in France emphasized women's "maternal and nurturant functions" and stressed the notion of "equality-in-difference" rather than espousing a more individualistic Anglo-American philosophy.6 Although maternity and sexual difference were certainly dominant tropes in French feminist discourse, focusing on the question of single women allows us to view the French movement from a different angle. (shrink)

Andrea Mansker révise ici la célèbre analyse de Robert Nye : le duel – institution résolument masculine s’il en est – a été la représentation ultime de l’honneur masculin bourgeois. Cet honneur, foncièrement hétérosexuel, était, selon Nye, incarné (embodied) dans le bourgeois, déjà construit selon un modèle biomédical des sexes ; l’honneur féminin bourgeois, également embodied et foncièrement hétérosexuel en opposition à l’honneur masculin, s’est constitué par « la chasteté et le mariage légi...

The problem of justifying legal punishment has been at the heart of legal and social philosophy from the very earliest recorded philosophical texts. However, despite several hundred years of debate, philosophers have not reached agreement about how legal punishment can be morally justified. That is the central issue addressed by the contributors to this volume. All of the essays collected here have been published in the highly respected journal Philosophy & Public Affairs. Taken together, they offer not only significant proposals (...) for improving established theories of punishment and compelling arguments against long-held positions, but also ori-ginal and important answers to the question, "How is punishment to be justified?"Part I of this collection, "Justifications of Punishment," examines how any practice of punishment can be morally justified. Contributors include Jeffrie G. Murphy, Alan H. Goldman, Warren Quinn, C. S. Nino, and Jean Hampton. The papers in Part II, "Problems of Punishment," address more specific issues arising in established theories. The authors are Martha C. Nussbaum, Michael Davis, and A. John Simmons. In the final section, "Capital Punishment," contributors discuss the justifiability of capital punishment, one of the most debated philosophical topics of this century. Essayists include David A. Conway, Jeffrey H. Reiman, Stephen Nathanson, and Ernest van den Haag. (shrink)

The scope and importance of the present work is manifest even to a casual glance; the actual heights of scholarly penetration and disinterestedness to which it rises can only be appreciated by the detailed examination of its text. From this latter examination, it readily appears that we are confronted with no ad hoc construction, no work cut, so to say, to fit a present need, however valid and cogent; but a work reflecting a near lifetime of application and animated by (...) a relentless devotion to documentary truth. For this reason, any account of it must, in simple justice, begin with a brief historical notice of the work itself. (shrink)

We propose protein localization dependent signal activation (PLDSA) as a model to describe pre‐existing protein partitioning between the cytosol, and membrane surface, as a means to modulate signal activation, specificity, and robustness. We apply PLDSA to explain possible molecular links between type II diabetes mellitus (T2DM) and Alzheimer's disease (AD) by describing Ca+2‐mediated interactions between the Src non‐receptor tyrosine kinase and p52Shc adaptor protein. We suggest that these interactions may serve as a contributing factor to disease development and progression. In (...) particular, we propose that signaling response is regulated, in part, by Ca+2‐mediated partitioning of lipid‐bound and soluble forms of Src and p52shc. Thus, protein‐protein interactions that drive signaling in response to extracellular ligand binding are also mediated by partitioning of signaling proteins between membrane‐bound and soluble populations. We propose that PLDSA effects may explain, in part, the evolutionary basis of promiscuous protein interaction domains and their importance in cellular function. (shrink)

I am now sitting in La Antigua, Guatemala. It's 6:00 a.m. Ancient church bells compete with their clanging. Some with a clear ringing, others of dead metal. For centuries this tiny town of some 20 square blocks was the very center of Christianity in the "new" world. Its philosophy was brought to this place, lock, stock, and barrel. And, from here it was funneled south to Peru and north to Mexico. Not a philosophy of "liberation." Just ask the Maya who (...) remain. (shrink)

Comparative study of the Mimamsa philosophy of Kumārila Bhaṭṭa and Prabhākaramiśra, 7th century philosophers.