Hudson has formulated two local deterministic theses and argued that both are incompatible with freedom. We argue that Hudson has half the story right. Moreover, reflection on Hudson’s theses brings out an important point for debates about freedom generally: that instead of focusing on the notion of entailment, debates about freedom should focus on the notions of explanation and sourcehood. Hudson’s theses provide an excellent case study for why the latter notions ought to take precedence over the former in debates (...) about freedom. (shrink)

Despite the importance of extrapair copulation (EPC) in human evolution, almost nothing is known about the design features of EPC detection mechanisms. We tested for sex differences in EPC inference-making mechanisms in a sample of 203 young couples. Men made more accurate inferences (φmen = 0.66, φwomen = 0.46), and the ratio of positive errors to negative errors was higher for men than for women (1.22 vs. 0.18). Since some may have been reluctant to admit EPC behavior, we modeled how (...) underreporting could have influenced these results. These analyses indicated that it would take highly sex-differentiated levels of underreporting by subjects with trusting partners for there to be no real sex difference. Further analyses indicated that men may be less willing to harbor unresolved suspicions about their partners’ EPC behavior, which may explain the sex difference in accuracy. Finally, we estimated that women underreported their own EPC behavior (10%) more than men (0%). (shrink)

Aggleton & Brown argue that a hippocampal-anterior thalamic system supports the “recollection” of contextual information about previous events, and that a separate perirhinal-medial dorsal thalamic system supports detection of stimulus “familiarity.” Although there is a growing body of human literature that is in agreement with these claims, when recollection and familiarity have been examined in amnesics using the process dissociation or the remember/know procedures, the results do not seem to provide consistent support. We reexamine these studies and describe the results (...) of an additional experiment using a receiver operating characteristic (ROC) technique. The results of the reanalysis and the ROC experiment are consistent with Aggleton & Brown's proposal. Patients with damage to both regions exhibit severe deficits in recollection and smaller, but consistent, deficits in familiarity. (shrink)

Foucault on Politics, Society and War interrogates Foucault's controversial genealogy of modern biopolitics. By insisting on 'life' as the key referent of power in the modern age, Foucault argues that politics grounds society in war, specifically race war, in ways that come to threaten the very human existence it is pledged to promote. These essays situate Foucault's arguments, clarify the correlation of sovereign- and bio-power and examine the relation of bios, nomos and race in relation to modern war.

This volume celebrates the career of John Martin Fischer, whose work on a wide range of topics over the past forty years has been transformative and inspirational. Fischer's semicompatibilist view of free will and moral responsibility is perhaps the most widely discussed view of its kind, and his emphasis on the significance of reasons-responsiveness as the capacity that underlies moral accountability has been widely influential. Aside from free will and moral responsibility, Fischer is also well-known for his work on freedom (...) and foreknowledge, the problem of evil, the badness of death, the meaning of life, and the allure of immortality. This volume gathers new essays by leading scholars on some of the major themes of Fischer's work, and it also includes a new piece by Fischer in which he offers a systematic reflection on and defense of the motivations that have shaped his theorizing about moral responsibility. Freedom, Responsibility, and Value will be of interest to scholars and students working on a variety of issues in metaphysics, ethics, and philosophy of religion. (shrink)

Hastings Center Report, Volume 52, Issue 3, Page 9-17, May–June 2022.

1 Evidence-based policy requires researchers to provide the answers to ecological questions that are of interest to policy makers. To find out what those questions are in the UK, representatives from 28 organizations involved in policy, together with scientists from 10 academic institutions, were asked to generate a list of questions from their organizations. 2 During a 2-day workshop the initial list of 1003 questions generated from consulting at least 654 policy makers and academics was used as a basis for (...) generating a short list of 100 questions of significant policy relevance. Short-listing was decided on the basis of the preferences of the representatives from the policy-led organizations. 3 The areas covered included most major issues of environmental concern in the UK, including agriculture, marine fisheries, climate change, ecosystem function and land management. 4 The most striking outcome was the preference for general questions rather than narrow ones. The reason is that policy is driven by broad issues rather than specific ones. In contrast, scientists are frequently best equipped to answer specific questions. This means that it may be necessary to extract the underpinning specific question before researchers can proceed. 5 Synthesis and applications. Greater communication between policy makers and scientists is required in order to ensure that applied ecologists are dealing with issues in a way that can feed into policy. It is particularly important that applied ecologists emphasize the generic value of their work wherever possible. (shrink)

The earlier volume in this series dealt with two religions of Indian origin, namely, Buddhism and Jainism. The Indian religious scene, however, is characterized by not only religions which originated in India but also by religions which entered India from outside India and made their home here. Thus religious life in India has been enlivened throughout its history by the presence of religions of foreign origin on its soil almost from the very time they came into existence. This volume covers (...) three such religions—Zoraoastrianism, Judaism, and Islam. In the case of Zoraostianism, even its very beginnings are intertwined with India, as Zoroastrianism reformed a preexisting religion which had strong links to the Vedic heritage of India. This relationship took on a new dimension when a Zoroastrian community, fearing persecution in Persia after its Arab conquest, sought shelter in western India and ultimately went on to produce India’s pioneering nationalist in the figure of Dadabhai Naoroji ( 1825-1917), also known as the Grand Old Man of India. Jews found refuge in south India after the destruction of the Temple by the Romans in 70 C.E. and have remained a part of the Indian religious scene since then, some even returning to Israel after it was founded in 1948. Islam arrived in Kerala as soon as it was founded and one of the earliest mosques in the history of Islam is found in India. Islam differs from the previously mentioned religions inasmuch as it went on to gain political hegemony over parts of the country for considerable periods of time, which meant that its impact on the religious life of the subcontinent has been greater compared to the other religions. It has also meant that Islam has existed in a religiously plural environment in India for a longer period than elsewhere in the world so that not only has Islam left a mark on India, India has also left its mark on it. Indeed all the three religions covered in this volume share this dual feature, that they have profoundly influenced Indian religious life and have also in turn been profoundly influenced by their presence in India. (shrink)

Unlike the first generation of critical theorists, contemporary critical theory has largely ignored technology. This is to the detriment of a critical theory of society – technology is now a central feature of our daily lives and integral to the contemporary form of capitalism. Rather than seek to rescue the first generation’s substantive theory of technology, which has been partly outmoded by historical developments, the approach adopted in this article is to engage with today’s technology through the conceptual apparatus offered (...) by the early Frankfurt School. This rationale is guided by the conviction that the core ideas of critical theory still offer a sound basis for assessing the nature of technology today. Through a reconstruction and engagement with some of the core concepts of first-generation critical theory, as well as the work of Bernard Stiegler and Andrew Feenberg, we can arrive at a more robust theory of technology, capable of critically interrogating the role of technology in contemporary society. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Utilitarianism in the Early American Republic by James E. CrimminsAndrew GustafsonUtilitarianism in the Early American Republic James E. Crimmins. Routledge, 2022.There are many important influences on American Pragmatism, but one which is frequently overlooked is the influence of Utilitarianism, both on American thought in general, and American Pragmatism in particular. It is difficult to imagine anyone better to write this book than James Crimmins. As a leading Bentham (...) scholar, among his twelve previously published books on utilitarianism, he is editor of the Bloomsbury Encyclopedia of Utilitarianism (Bloomsbury, 2013) and the four-volume set Utilitarians and Their Critics in America, 1789–1914 (Thoemmes Continuum, 2005). His vast knowledge of the history of utilitarianism, which he has spent his entire career investigating, makes him the perfect author for this very helpful book on the influences of utilitarianism in early American thought. It is a rich sourcebook that can help direct anyone looking to do more research in this area. Here, Crimmins provides a thorough historical account of the influence of utilitarianism on the development of early American thought and the rise of pragmatism, giving reason to believe that utilitarianism was more impactful on American pragmatism than is often realized.The first chapter highlights why utilitarian influence on American law and politics is overlooked and why it should not be. Chapters 2 and 3 explain how American thought leaders came to know of Bentham's work, and chapters 4–7 discuss concrete examples of thinkers who brought utilitarianism to bear on issues in America (for example, Hoffman on legal studies in chapter 4, Livingston on legislative law in chapter 5, the death penalty debate in chapter 6, and Thomas Cooper's wide-ranging influences in chapter 7). The epilogue provides a specific set of arguments for why the utilitarians' influence on American Pragmatism should be more widely recognized and investigated.Crimmins begins the book by explaining why utilitarianism, as an influence in early American politics, is typically excluded and ignored by thinkers from John Dewey to Élie Halévy. One reason is that William Paley's Principles of Political and Moral Philosophy (which was used widely as a moral text in US universities throughout the 1800s) was published in 1785, and Bentham's An Introduction to the Principles of Morals and Legislation was published in 1789, and even then Bentham's ideas didn't gain public circulation (and then only in French) until Etienne Dumont published the three-volume Traités de législation civile et pénale in 1802. But the more important reason utilitarianism [End Page 106] has not received attention, according to Crimmins, is due to the dominant focus placed on Locke's natural law and rights view being the lens by which American politics has been understood. Some have challenged this Lockean consensus and pointed out that republican virtues drawn from the ancient Greeks and others show up in ideas such as the "right to happiness" (which is a right that is found nowhere in Locke) (20). Crimmins shows that there was a very strong emphasis on "public utility," "general welfare," and happiness, and this frequently outweighed concerns for natural rights for thinkers like Thomas Paine, John Adams, Nathaniel Chipman, Joseph Haven, and many other early American thinkers. Furthermore, utilitarian considerations can be found in the Constitution and federalist papers, and even Tocqueville explained American thinking through the lens of utilitarian concerns.Bentham was ambitious in attempting to promote codification of law in many countries worldwide. While Bentham had made offers (some accepted, some rejected) to help in the codification of law to various countries, ranging from Catherine the Great's Russia to France, Portugal, Spain, and numerous South American countries, he spent much of the last quarter of his life focused on trying to provide his services to the new United States. In chapter 2, Crimmins provides a history of the dissemination of Bentham's ideas in the United States, highlighting some of the key promoters of his ideas in the United States, including Richard Hildreth and John Neal, as well as John O'Sullivan, Gilbert Vale, and, of course, Thomas Cooper. Crimmins also provides a meticulous account of Bentham's personal attempts... (shrink)

Neal Wood, Reflections on Political Theory: A Voice of Reason from the Past , x + 178 pp., ?35.00, ISBN 0 333 96880 8. Reviewed by Christopher Brooke. James Connelly, Metaphysics, Method and Politics: The Political Philosophy of R.G. Collingwood , ix + 336 pp., ?25.00/$40.00, ISBN 0 907845 312. Reviewed by Andrew Lockyer. Ekbert Faas, The Genealogy of Aesthetics , xiv + 439 pp., ?47.50, ISBN 0 521 81182 1. Reviewed by John Hope Mason. Christopher Kelly, Rousseau (...) as Author: Consecrating One’s Life to the Truth , ix + 209 pp., ?13.50/$19.00, ISBN 0 226 43024 3 . Reviewed by Timothy O’Hagan. Douglas R. Howland, Translating the West: Language and Political Reason in Nineteenth- Century Japan , xvi + 292 pp., $27.95, ISBN 0 8248 2462 8. Reviewed by Michael Mosher. Articulating America: Fashioning a National Political Culture in Early America, Essays in Honor of J.R. Pole, ed. Rebecca Starr , xi + 276 pp., ?31.00/$40.00, ISBN 0 7425 2076 5. Reviewed by Paul Carrese. Alberto Spektorowski, The Origins of Argentina’s Revolution of the Right , x + 269 pp., $30.00, ISBN 0 268 02011 6. Reviewed by David Rock. Joan Cocks, Passion and Paradox: Intellectuals Confront the National Question , xi + 220 pp., $16.95, ISBN 0 691 07468 2. Reviewed by David Miller. Samuel Pufendorf, Eris Scandica und andere polemische Schriften über das Naturrecht, ed. Fiammetta Palladini, Vol. 5 of Gesammelte Werke, ed. Wilhelm Schmidt-Biggemann , xxi + 489 pp., 14 illustrations, –158.00, ISBN 3 05 003605 2. Reviewed by Michael J. Seidler. Ivan Strenski, Contesting Sacrifice: Religion, Nationalism, and Social Thought in France , ix + 228 pp., $37.50/?26.50, ISBN 0 226 77736 7. Reviewed by Steven C. Hause. (shrink)

In 1999, Neale Donald Walsch wrote three little books, each focusing on different areas of life: Neale Donald Walsch on Relationships, Neale Donald Walsch on Holistic Living, and Neale Donald Walsch on Abundance and Right Livelihood. In 2010, these three books were published in a single volume as Neale Donald Walsch's Little Book of Life. Walsch describes this book as a thousand pages of dialogue in the Conversations with God series reduced down to a few salient points and a few (...) very direct observations about how to render them functional. Readers can think of this book as either Conversations with God in a Nutshell or the Essential Conversations with God. Here are the basic principles for: Satisfying personal relationships; Living a joyful, harmonious life; Discovering authentic prosperity. Walsch's words provide hope and help for readers living in particularly challenging times. This is indeed Walsch's essential life guide for twenty-first century readers."--Back cover. (shrink)

I develop and defend a sense-datum theory of perception. My theory follows the spirit of classic sense-datum theories: I argue that what it is to have a perceptual experience is to be acquainted with some sense-data, where sense-data are private particulars that have all the properties they appear to have, that are common to both perception and hallucination, that constitute the phenomenal characters of perceptual experiences, and that are analogous to pictures inside one’s head. But my theory also diverges from (...) conventional sense-datum theories in some key respects: on my view, (1) sense-data are first-person presentations of neural states, (2) the sensational qualities of sense-data differ in kind from the sensible qualities of external objects, and (3) sense-data are the vehicles in virtue of which we perceive, rather than the objects that we perceive. I argue that this package of claims is appropriately labeled ‘sense-datum theory’, and that the resultant view ought to be a live contender in contemporary philosophy of perception. (shrink)

In this paper, we examine the case of psychedelic medicine for Alzheimer’s disease and related dementias (AD/ADRD). These “mind-altering” drugs are not currently offered as treatments to persons with AD/ADRD, though there is growing interest in their use to treat underlying causes and associated psychiatric symptoms. We present a research agenda for examining the ethics of psychedelic medicine and research involving persons living with AD/ADRD, and offer preliminary analyses of six ethical issues: the impact of psychedelics on autonomy and consent; (...) the impact of “ego dissolution” on persons experiencing a pathology of self; how psychedelics might impact caregiving; the potential exploitation of patient desperation; institutional review boards’ orientation to psychedelic research; and methods to mitigate inequity. These ethical issues are magnified for AD/ADRD but bear broader relevance to psychedelic medicine and research in other clinical populations. (shrink)

When philosophers talk about descriptions, usually they have in mind singular definite descriptions such as ‘the finest Greek poet’ or ‘the positive square root of nine’, phrases formed with the definite article ‘the’. English also contains indefinite descriptions such as ‘a fine Greek poet’ or ‘a square root of nine’, phrases formed with the indefinite article ‘a’ (or ‘an’); and demonstrative descriptions (also known as complex demonstratives) such as ‘this Greek poet’ and ‘that tall woman’, formed with the demonstrative articles (...) ‘this’ and ‘that’. Following the custom in philosophy, in this chapter often we use ‘description’ as short for ‘definite description’; and following the custom in linguistics, often we use ‘definite’, ‘indefinite’, and ‘demonstrative’ as shorthand nouns. For the most part we focus on definite and indefinites, although a few words about demonstratives are called for. At the centre of debates about descriptions is the matter of whether they are devices of reference or of predication (simple or higher-order), and much discussion focuses on how various proposals are to be incorporated into broader theories of the semantics of natural language. But philosophical interest goes beyond the confines of linguistics, logic, and the philosophy of language because choices made about the semantics of descriptions have repercussions elsewhere, particularly in epistemology and metaphysics. A simple match of form and meaning appears to fail.1 First, many occurrences of expressions of both forms ‘the φ’ and ‘a φ’ appear to be used to talk about particular individuals. Consider (1). (shrink)

The COVID-19 pandemic has been accompanied by an “infodemic” of misinformation and conspiracy theory. This article points to three explanatory factors: the challenge of forming accurate beliefs when overwhelmed with information, an implausibly individualistic conception of epistemic virtue, and an adversarial information environment that suborns epistemic dependence. Normally we cope with the problems of informational excess by relying on other people, including sociotechnical systems that mediate testimony and evidence. But when we attempt to engage in epistemic “superheroics” - withholding trust (...) from others and trying to figure it all out for ourselves – these can malfunction in ways that make us vulnerable to forming irrational beliefs. Some epistemic systems are prone to coalescing audiences around false conspiracy theories. This analysis affords a new perspective on philosophical efforts to understand conspiracy theories and other epistemic projects prone to collective irrationality. (shrink)

There are two kinds of time-bias: near-bias and future-bias. While philosophers typically hold that near-bias is rationally impermissible, many hold that future-bias is rationally permissible. Call this normative hybridism. According to arbitrariness objections, certain patterns of preference are rationally impermissible because they are arbitrary. While arbitrariness objections have been levelled against both near-bias and future-bias, the kind of arbitrariness in question has been different. In this paper we investigate whether there are forms of arbitrariness that are common to both kinds (...) of preferences, and hence whether there are versions of the arbitrariness objection that are objections both to near-bias and future-bias. If there are, then this might go some way towards undermining normative hybridism and to defending a thorough-going time-neutralism. (shrink)

In this paper I will introduce a new compatibilist account of free action: indirect conscious control compatibilism, or just indirect compatibilism for short. On this account, actions are free either when they are caused by compatibilist‐friendly conscious psychological processes, or else by sub‐personal level processes influenced in particular ways by compatibilist‐friendly conscious psychological processes. This view is motivated by a problem faced by a certain family of compatibilist views, which I call conscious control views. These views hold that we act (...) freely when we act in a way that is caused by certain conscious psychological processes. One problem for such views is that current neuroscience suggests that most of our actions are not caused by such processes. Instead, many of the actions we typically suppose are free are caused by sub‐personal level processes and hence would count as not free according to contemporary conscious control views. I argue, contra these views, that many actions caused by these sub‐personal level processes are indirectly free. Further, most of the actions we ordinarily judge to be free are free in this indirect manner. (shrink)

The dialogue focuses on the major issues of the contemporary theoretical debate on judicial review and the Supreme Court's role in American constitutional democracy. The discussion begins with the US Supreme Court's case Hamdan v. Rumsfeld, successfully argued by Prof. Katyal last year, and covers important issues such as the separation and balance of powers after 9/11, the legitimacy of the laws of terror, the relation between US constitutional law and foreign law, the counter‐majoritarian difficulties posed by the exercise of (...) judicial review, and the legal academy's influence on legal practice. (shrink)

We suggest that there is confusion between why consciousness developed and what additional functions, through continued evolution, it has co-opted. Consider episodic memory. If we believe that episodic memory evolved solely to accurately represent past events, it seems like a terrible system—prone to forgetting and false memories. However, if we believe that episodic memory developed to flexibly and creatively combine and rearrange memories of prior events in order to plan for the future, then it is quite a good system. We (...) argue that consciousness originally developed as part of the episodic memory system—quite likely the part needed to accomplish that flexible recombining of information. We posit further that consciousness was subsequently co-opted to produce other functions that are not directly relevant to memory per se, such as problem-solving, abstract thinking, and language. We suggest that this theory is compatible with many phenomena, such as the slow speed and the after-the-fact order of consciousness, that cannot be explained well by other theories. We believe that our theory may have profound implications for understanding intentional action and consciousness in general. Moreover, we suggest that episodic memory and its associated memory systems of sensory, working, and semantic memory as a whole ought to be considered together as the conscious memory system in that they, together, give rise to the phenomenon of consciousness. Lastly, we suggest that the cerebral cortex is the part of the brain that makes consciousness possible, and that every cortical region contributes to this conscious memory system. (shrink)

This paper looks at the nature of normal-proper functions and the role they play in theories of representational content. More specifically: I lay down two desiderata for a theory which tries to capture what's distinctive of normal-proper functions and discuss two prominent theories which claim to satisfy them. I discuss the advantages of having normal-proper functions ground a theory of representational content. And, I look at both orthodox and heterodox versions of such theories.

The work of the late Paul Grice (1913–1988) exerts a powerful influence on the way philosophers, linguists, and cognitive scientists think about meaning and communication. With respect to a particular sentence φ and an “utterer” U, Grice stressed the philosophical importance of separating (i) what φ means, (ii) what U said on a given occasion by uttering φ, and (iii) what U meant by uttering φ on that occasion. Second, he provided systematic attempts to say precisely what meaning is by (...) providing a series of more refined analyses of utterer’s meaning, sentence meaning, and what is said. Third, Grice produced an account of how it is possible for what U says and what U means to diverge. Fourth, by characterizing a philosophically important distinction between the “genuinely semantic” and “merely pragmatic” implications of a statement, Grice clarified the relationship between classical logic and the semantics of natural language. Fifth, he provided some much needed philosophical ventilation by deploying his notion of “implicature” to devastating effect against certain overzealous strains of “Ordinary Language Philosophy,” without himself abandoning the view that philosophy must pay attention to the nuances of ordinary talk. Sixth, Grice undercut some of the most influential arguments for a philosophically significant notion of “presupposition.” Today, Grice’s work lies at the center of research on the semantics-pragmatics distinction and shapes much discussion of the relationship between language and mind. In a nutshell, Grice has forced philosophers and linguists to think very carefully about the sorts of facts a semantic theory is supposed to account for and to reflect upon the most central theoretical notions, notions that otherwise might be taken for granted or employed without due care and attention. To be sure, Grice’s own positive proposals have their weaknesses; but in the light of his work any theory of meaning that is to be taken at all seriously must now draw a sharp line between genuinely semantic facts and facts pertaining to the nature of human interaction.. (shrink)

This book offers a compelling examination of the problem of evil and the doctrine of sin. It engages with and advances extant discussions on the topic by drawing together philosophical arguments, theological reflections, scientific evidence, Biblical exegesis, and real-life stories. The chapters provide a comprehensive evaluation of objections by anti-theodicists and atheists, and bring recent philosophical work concerning the arguments for Christian theism and advances in science and religion to bear on the discussion. The author defends the Cosmic Conflict Theodicy (...) against philosophical and theological objections, and uses it together with the Connection Building Theodicy, Adamic Fall Theodicy, arguments for divine hiddenness, and Afterlife Theodicy to address the vexing problem of horrendous evil. (shrink)

A novel solution to the knowability paradox is proposed based on Kant’s transcendental epistemology. The ‘paradox’ refers to a simple argument from the moderate claim that all truths are knowable to the extreme claim that all truths are known. It is significant because anti-realists have wanted to maintain knowability but reject omniscience. The core of the proposed solution is to concede realism about epistemic statements while maintaining anti-realism about non-epistemic statements. Transcendental epistemology supports such a view by providing for a (...) sharp distinction between how we come to understand and apply epistemic versus non-epistemic concepts, the former through our capacity for a special kind of reflective self-knowledge Kant calls ‘transcendental apperception’. The proposal is a version of restriction strategy: it solves the paradox by restricting the anti-realist’s knowability principle. Restriction strategies have been a common response to the paradox but previous versions face serious difficulties: either they result in a knowability principle too weak to do the work anti-realists want it to, or they succumb to modified forms of the paradox, or they are ad hoc. It is argued that restricting knowability to non-epistemic statements by conceding realism about epistemic statements avoids all versions of the paradox, leaves enough for the anti-realist attack on classical logic, and, with the help of transcendental epistemology, is principled in a way that remains compatible with a thoroughly anti-realist outlook. (shrink)

This book is an original examination of attempts to dislodge a cornerstone of modern philosophy: the idea that our thoughts and utterances are representations ...

I offer a new deductive formulation of the Moral Argument for the existence of God which shows how one might argue for the conclusion that, if one affirms moral realism (traditionally understood as a metaethical view which acknowledges the existence of objective moral truths), one should affirm theism. The new formulation shows that these objective moral truths are either brute facts, or they are metaphysically grounded in an impersonal entity, a non-divine personal entity, or a divine personal entity i.e., God. (...) I illustrate how the alternatives to God can in principle be excluded based on the essential characteristics of those alternative hypotheses and of certain objective moral truths. I demonstrate that my deductive formulation is better than other formulations, and that it is helpful for future work on the Moral Argument. (shrink)

Considerable evidence from preclinical and clinical investigations implicates disturbances of brain dopamine (DA) function in the pathophysiology of several psychiatric and neurologic disorders. We describe a neural model that may help organize theseindependent experimental observations. Cortical regions classically associated with the limbic system interact with infracortical structures, including the nucleus accumbens, ventral pallidum, and dorsomedial nucleus of the thalamus. In our model, overactivity in forebrain DA systems results in the loss of lateral inhibitory interactions in the nucleus accumbens, causing disinhibition (...) of pallidothalamic efferents; this in turn causes rapid changes and a loss of focused corticothalamic activity in cortical regions controlling cognitive and emotional processes. These effects might be manifested clinically by some symptoms of psychoses. Underactivity of forebrain DA results in excess lateral inhibition in the nucleus accumbens, causing tonic inhibition of pallidothalamic efferents; this perpetuates tonic corticothalamic activity and prevents the initiation of new activity in other critical cortical regions. These effects might be manifested clinically by some symptoms of depression. This model parallels existing explanations for the etiology of several movement disorders, and may lead to testable inferences regarding the neural substrates of specific psychopathologies. (shrink)

Autoinhibition is a design principle realized in many molecular mechanisms in biology. After explicating the notion of a design principle and showing that autoinhibition is such a principle, we focus on how researchers discovered instances of autoinhibition, using research establishing the autoinhibition of the molecular motors kinesin and dynein as our case study. Research on kinesin and dynein began in the fashion described in accounts of mechanistic explanation but, once the mechanisms had been discovered, researchers discovered that they exhibited a (...) second phenomenon, autoinhibition. The discovery of autoinhibition not only reverses the pattern in terms of which philosophers have understood mechanism discovery but runs counter to the one phenomenon-one mechanism principle assumed to relate mechanisms and the phenomena they explain. The ubiquity of autoinhibition as a design principle, therefore, necessitates a philosophical understanding of mechanisms that recognizes how they can participate in more than one phenomenon. Since mechanisms with this design are released from autoinhibition only when they are acted on by control mechanisms, we advance a revised account of mechanisms that accommodates attribution of multiple phenomena to the same mechanism and distinguishes them from other processes that control them. (shrink)

It is commonplace to describe the pragmatist conception of truth as incompatible with correspondence theory. This popular description relies on a deflationary reading of Peirce and James’s many apparent endorsements of correspondence. This reading says they regarded it as a mere platitude or truism, not as a substantive piece of philosophical theorizing. There are two main reasons typically offered in support of this platitude narrative – its consonance with Peirce’s original formulation of PT from 1878, and the objections that pragmatists (...) frequently raised against various notions traditionally associated with CT. I argue that neither reason is compelling and that PT and CT are compatible conceptions of truth. (shrink)

A famous mathematical theorem says that the sum of an infinite series of numbers can depend on the order in which those numbers occur. Suppose we interpret the numbers in such a series as representing instances of some physical quantity, such as the weights of a collection of items. The mathematics seems to lead to the result that the weight of a collection of items can depend on the order in which those items are weighed. But that is very hard (...) to believe. A puzzle then arises: How do we interpret the metaphysical significance of this mathematical theorem? I first argue that prior solutions to the puzzle lead to implausible consequences. Then I develop my own solution, where the basic idea is that the weight of a collection of items is equal to the limit of the weights of its finite subcollections contained within ever-expanding regions of space. I show how my solution is intuitively plausible and philosophically motivated, how it reveals an underexplored line of metaphysical inquiry about quantities and locations, and how it elucidates some classic puzzles concerning supertasks. (shrink)

In this paper, I argue that nonhuman animals can be subject to epistemic injustice. I consider Miranda Fricker’s (2007) account of the nature of the harm of epistemic injustice and highlight that it requires that a knower be invested in being recognized as a knower. I argue that a focus on know-how, rather than testimony or concepts for self-understanding and communication, can serve to highlight how nonhuman animals can suffer epistemic injustice without an investment in recognition, by focusing on distributive (...) justice concerning epistemic goods. Drawing from work in animal ethology and movement ecology, I argue that human interruption of animal lifeways has negative downstream effects on nonhuman animals’ ability to acquire ‘answers’ to ‘questions’ they have an interest in answering: namely, acquiring both true beliefs about conspecifics and their environment, as well as acquisition of behaviors and skills that enable everyday successful coping, and that these interruptions can constitute epistemic injustice. (shrink)

Clinical trials for acute conditions such as myocardial infarction and stroke pose challenges related to informed consent due to time limitations, stress, and severe illness. Consent processes shou...

An increasing amount of contemporary philosophy of mathematics posits, and theorizes in terms of special kinds of mathematical modality. The goal of this paper is to bring recent work on higher-order metaphysics to bear on the investigation of these modalities. The main focus of the paper will be views that posit mathematical contingency or indeterminacy about statements that concern the `width' of the set theoretic universe, such as Cantor's continuum hypothesis. Within a higher-order framework I show that contingency about the (...) width of the set-theoretic universe refutes two orthodoxies concerning the structure of modal reality: the view that the broadest necessity has a logic of S5, and the "Leibniz biconditionals" stating that what is possible, in the broadest sense of possible, is what is true in some possible world. Nonetheless, I suggest that the underlying picture of modal set-theory is coherent and has attractions. (shrink)

Does utterance understanding require reliable (i.e. non-lucky) recovery of the speaker’s intended proposition? There are good reasons to answer in the affirmative: the role of understanding in supporting testimonial knowledge seemingly requires such reliability. Moreover, there seem to be communicative analogues of Gettier cases in which luck precludes the audience’s understanding an utterance despite recovering the intended proposition. Yet, there are some major problems with the view that understanding requires such reliability. Firstly, there are a number of cases in which (...) understanding seems to occur in a lucky way. In light of these cases I argue that we need to narrow down the precise sense in which understanding precludes luck – the anti-luck condition attached to linguistic understanding is importantly different to anti-luck conditions typically applied to knowledge. Secondly, Megan Hyska has recently argued that, assuming understanding precludes luck, we get a communicative analogue of the value problem for knowledge. i.e. why is it better to meet the other conditions for understanding in a reliable way than in a lucky way? It is natural to assume that we can simply port over our favoured responses to the epistemic value problem in response to Hyska’s challenge. I argue that, due to the difference between epistemic and communicative luck (discussed in response to the first problem), this cannot be done. The epistemic and communicative value problems will require different solutions. I close by sketching the beginnings of an alternative answer to the value problem for communication. (shrink)

This paper introduces and argues for contrastivism about intentions. According to contrastivism, intention is not a binary relation between an agent and an action. Rather, it is a ternary relation between an agent, an action, and an alternative. Contrastivism is introduced via a discussion of cases of known but (apparently) unintended side effects. Such cases are puzzling. They put pressure on us to reject a number of highly compelling theses about intention, intentional action, and practical reason. And they give rise (...) to a puzzle about rather than constructions such as ‘I intend to φ rather than ψ’: In side effect cases it can seem wrong to claim that the subject intends to φ, yet acceptable to claim that they intend to φ rather than ψ. This cries out for explanation. Contrastivism provides a unified response to all of these problems. (shrink)

I present new counterexamples to the asymmetry of grounding: we have prima facie reason to think that some conditional probabilities partially ground their inverse conditional probabilities, and vice versa. These new counterexamples may require that we reject the asymmetry of grounding, or alternatively may require that we reject one or more of the assumptions which enable the counterexamples. Either way, by reflecting on these purported counterexamples to grounding asymmetry we learn something important, either about the formal properties of grounding, or (...) about the nature of probability. (shrink)

In this study, we test the interactive effect on ethical decision-making of (1) personal characteristics, and (2) personal expectanciesbased on perceptions of organizational rewards and punishments. Personal characteristics studied were cognitive moral developmentand belief in a just world. Using an in-basket simulation, we found that exposure to reward system information influenced managers’ outcome expectancies. Further, outcome expectancies and belief in a just world interacted with managers’ cognitive moral development to influence managers’ ethical decision-making. In particular, low-cognitive moral development managers who (...) expected that their organization condoned unethical behavior made less ethical decisions while high cognitive moral development managers became more ethical in this environment. Low cognitive moral development managers also behaved less ethically when their belief in a just world was high. (shrink)