Writing this review on a plane headed to a conference on queering sexuality, with newly shorn pink hair, I note to myself that I’m hitting a lot of stereotypes. I’m a philosopher, a professor of women studies, a feminist researcher, a parent who identifies as bisexual, and it’s with all these hats on that I’m reading and reviewing Maggie Nelson’s book The Argonauts. I’m starting this way because it seems odd to review The Argonauts without any personal detail, though the (...) inclusion of personal information isn’t something I get to do much as an academic philosopher. But The Argonauts is such a personal and philosophical book that it calls for that kind of response from those who read it. I won’t... (shrink)

The introductory chapter, entitled 'The Subject, Method and Scope of this Enquiry,' details how anthropology is to be pursued as a science and advocates the method of participant observation.

While Statius' decision to treat events in landlocked Thebes offered limited opportunity to integrate into his poem a maritime episode, which had become a staple epic ingredient by the first centurya.d.,theThebaidis dotted with references to the Argonauts' quest for the Golden Fleece, including a narrative flashback of the crew's time at Lemnos (Theb. 5.335–498). Following in a long tradition of cross-contamination between Argonautic and Theban literary texts (as shown by, for example, the ApollonianArgonautica's use of Antimachus'Thebaid), Statius' poem also evokes (...) works of literature which narrate the legend, notably theArgonauticasof Apollonius Rhodius and Valerius Flaccus. A lack of scholarly focus on this latter area has generally led to a piecemeal scrutiny of individual allusive passages rather than a systematic treatment. However, Stover's recent paper paves the way for a more productive approach through its contention that theThebaidmakes widespread use of the mythic subject matter: ‘It … appears that Statius frequently appropriates the Argonautic tradition and that he does so largely to present the Argives as quasi Argonauts. This suggests that their adventure to conquer Thebes is analogous to the Argonauts’ voyage to Colchis.'. (shrink)

This Article tells the story of two legal cooperation projects established by the Israeli Ministry of Justice in the 1950s and 1960s. The Article argues that the history of these projects can suggest a new way of understanding the process of legal transplantation. Much of the literature on legal transplants focuses on the legal norms transplanted. This Article seeks to shift the focus of the debate from a discussion of the legal norms transplanted to a discussion of the social acts (...) involved in the process of transplantation. The Article argues that while transplantation may be motivated by practical considerations, such as the desire to obtain foreign norms which are deemed superior to local law, it is sometimes also a process of signaling. The two legal cooperation projects discussed in the Article, it is argued, were, to a certain extent, signaling devices used to communicate to Israel’s potential allies the fact that Israel was part of the civilized world, and thus a partner worthy of its cooperation, and also the fact that Israel was a state stable and strong enough to survive in the hostile environment into which it was born. (shrink)

Since the word "History" has its origins in the domain of inquiry, I call myself an historian to the extent to which I have tried to study voyages of discovery in a manner as personal as possible, and I have presented the results of my work in a number of books and articles. The short study which follows is not an attempt to recapitulate what has already been published. Rather, I have tried here to present a brief synthesis of my (...) reflections on one of the themes which I have undertaken to outline. (shrink)

Over the last decades, it has become evident that highly complex networks of regulators govern post‐transcriptional regulation of gene expression. A novel class of Argonaute (Ago)‐associated RNA molecules, the agotrons, was recently shown to function in a Drosha‐ and Dicer‐independent manner, hence bypassing the maturation steps required for canonical microRNA (miRNA) biogenesis. Agotrons are found in most mammals and associate with Ago as ∼100 nucleotide (nt) long RNA species. Here, we speculate on the functional and biological relevance of agotrons: (...) (i) agotrons could serve as non‐promiscuous miRNA‐like regulators with reduced off‐targeting or (ii) agotrons could encompass other putative functions, such as protecting Ago proteins from taking up aberrant short RNAs or by rescuing and stabilizing otherwise unloaded Ago‐proteins from degradation. Collectively, agotrons have emerged as a novel class of interesting non‐coding RNA molecules, but their full functional potential and biological impact still remain to be disclosed. (shrink)

This brief meditation on Maggie Nelson's The Argonauts reads it as elaborating a politics and ethics of vulnerability in both its thinking and its formal qualities, thereby showing us the radical aesthetic, personal and political potential of this state of apparent unguardedness. I consider, in turn, the text's treatment of emotional vulnerability, physical vulnerability, the vulnerability of gender and our vulnerability to gender, as well as the vulnerabilities of the apparently confessional writer and of the text itself.

In plants, virus‐derived double‐stranded RNA is processed into small interfering (si)RNAs by RNAse III‐type enzymes. siRNAs are believed to guide an RNA‐induced silencing complex (RISC) to promote sequence‐specific degradation (or ‘slicing’) of homologous viral transcripts. This process, called RNA silencing, likely involves Argonaute (AGO) proteins that are known components of plant and animal RISCs. Plant viruses commonly counteract the silencing immune response by producing suppressor proteins, but the molecular basis of their action has remained largely unclear. A recent study (...) by Zhang and colleagues1 now shows that the 2b suppressor of Cucumber mosaic virus directly interacts with Arabidopsis AGO1 and inhibits its slicing activity, suggesting that AGO1 might be a component of the elusive plant antiviral RISC. BioEssays 29:319–323, 2007. © 2007 Wiley Periodicals, Inc. (shrink)

This article explores what might constitute the good-enough reader of Maggie Nelson's The Argonauts. Prompted by Nelson's use of D.W. Winnicott's theory of the good-enough mother whose insufficiencies generate the infant's capacity to tolerate ordinary frustration and move beyond both idealizations and denigrations, I argue that the good-enough reader here would be the one who resists the temptation to idealize both the book and its author. This argument is presented as an attempt to open up some spaces for the discussion (...) of ambivalent responses to this book, beyond the rather deferential fandom that has characterized the psychic life of its reception. (shrink)

Readers in love with Maggie Nelson’s The Argonauts have often praised her ability to use the analytic capacities and citational resources of critical theory to advance her personal narrative about queer sex and kinship. This essay takes stock of Nelson’s genre-bending conventions by reading the visual organization of the printed book against its digital copy in order to deliberate on questions of materiality, authorship, and identity.

I argue that Statius appropriated material from the epics of Apollonius and Valerius Flaccus for his depiction of the vatic activity of Melampus and Amphiaraus and the latter's subsequent confrontation with Capaneus in Thebaid 3. I suggest that Statius modeled the confrontation between Capaneus and Amphiaraus on the neikos that erupts between Idas and Idmon in Apollonius' Argonautica. For the consecutive prophecies of Melampus and Amphiaraus, Statius drew inspiration from the dueling prophecies of Mopsus and Idmon in Valerius' poem. In (...) particular, Statius' allusive gestures function to distinguish his epic project from that of his Flavian predecessor. (shrink)

AbstractmiRNA‐mediated gene repression and ubiquitin‐dependent processes are among the oldest and most versatile mechanisms that control multiple molecular pathways, rather than just protein turnover. These systems were discovered decades ago and have become among the most studied. All systems within cells are interconnected, and these two are no exception: the plethora of studies have demonstrated that the activity of the miRNAs system depends on players of the ubiquitin‐centered universe of processes, and vice versa. This review focuses on recent progress that (...) highlights that very similar mechanisms of regulation of miRNAs by ubiquitin‐related processes are likely to be found in distantly related species, including animals, plants, and viruses. Most of them occur through the ubiquitination of Argonaute proteins, but some of the other miRNA system factors are also regulated. This suggests that their regulatory relationships are either ancient evolutionary acquisitions or have arisen independently in different kingdoms. (shrink)

A controversy among ancient geographers about the localisation of the Argonauts’ quest for the golden fleece has deeper methodological implications because it reflects divergent views on how to fill gaps in the account that serves as one’s source. Reconstructing the controversy step by step, the article aims to bring to light these methodological implications. In so doing, it also demonstrates that the extant editions unjustifiably curtail the text of the relevant fragment from Demetrius of Scepsis. And it argues for a (...) new interpretation specifically of how Demetrius assessed Homer’s references to the Argonauts. (shrink)

The Argonauts combines high theory and the everyday. It does this by combining lofty thought, the quotidian, close attention to words and ideas and stray thoughts, and desire. It does this through form, the way it blends and refuses genre, the way it skips from one thought or story to another, and making them connect by virtue of contiguity. The Argonauts refuses form in a way that parallels how Maggie's and Harry's bodies and identities refuse gender taxonomy. It also refuses (...) genre, referred to variously as theory, memoir, and autotheory. While it queers form and family, it also queers feelings. (shrink)

This essay reads The Argonauts against a preceding literature of queer and trans parenting, specifically by women of colour, to account for absences and evasions in Maggie Nelson's relation to queer feminist literary history. Resituating her quotation about “kinship systems” from Judith Butler into Butler's discussion of house mothers in ball culture, it calls attention to the erasure of queer racialized embodiment and intellection from Nelson's account, emblematized by Cherríe Moraga's Medea and – as embodied site of “shit and labor” (...) – the perineum, figuring the work of connection. (shrink)

‘The tale of the Argonauts was among the most popular myths in Greek and Roman literature of all periods.’ There was, however, not inconsiderable variation in certain aspects of the narrative: in the inclusion or exclusion of entire episodes; in (un)expected divergences from more authoritative versions of the story; and in the details of minutiae. In the Argonautic choral odes of Seneca'sMedea(301–79 and 579–669), and in Valerius Flaccus’ incomplete epic, there is a conspicuous, learned engagement with much of the earlier (...) tradition that hints at versions of the myth which are divergent from those that the two poets privilege in their respective narratives. Such moments serve to assert the playwright's and the epicist's status asdocti poetae, and to engage the learned reader in a (re)negotiation of the tradition; at times, an awareness of a literary past seems to be given to particular characters too so as to heighten the reader's experience of the narrative—by a sort of prolepsis—as it unfolds. (shrink)

When the Argonauts reach the island of Lemnos, Apollonius of Rhodes tells us, they send their herald Aethalides to the ruler of the island. Such a means of establishing contact and requesting safe passage was the norm in the Homeric world; there heralds acted as intermediaries between commanders and subordinates or between groups of people. In preliterate societies, heralds facilitated communication: messages were transmitted through memorization and repetition rather than by means of writing. While verbatim repetition was no doubt a (...) necessary feature of this form of communication, its wholesale transference into Homeric poetry was not necessarily the logical corollary. Nonetheless, we know of such repetitions precisely because of their appearance in the Homeric poems. It is now widely accepted that such passages are a result of the oral style of composition in which the oral poet repeats passages just as he uses shorter formulaic phrases. The debate embedded in the A-scholia of the Iliad suggests that repeated passages were a source of contention already in antiquity. While it is more common to see the scholiasts trying to decide which passage is ‘correct’ and which should be athetized, this provides evidence that athetization was not a unanimous impulse. The scholiast defends 2.60–71, part of which is repeated for the third time, against Zenodotus. (shrink)

Recent experimental evidence suggests that most of the genome is transcribed into non‐coding RNAs. The initial transcripts undergo further processing generating shorter, metabolically stable RNAs with diverse functions. Small nucleolar RNAs (snoRNAs) are non‐coding RNAs that modify rRNAs, tRNAs, and snRNAs that were considered stable. We review evidence that snoRNAs undergo further processing. High‐throughput sequencing and RNase protection experiments showed widespread expression of snoRNA fragments, known as snoRNA‐derived RNAs (sdRNAs). Some sdRNAs resemble miRNAs, these can associate with argonaute proteins (...) and influence translation. Other sdRNAs are longer, form complexes with hnRNPs and influence gene expression. C/D box snoRNA fragmentation patterns are conserved across multiple cell types, suggesting a processing event, rather than degradation. The loss of expression from genetic loci that generate canonical snoRNAs and processed snoRNAs results in diseases, such as Prader‐Willi Syndrome, indicating possible physiological roles for processed snoRNAs. We propose that processed snoRNAs acquire new roles in gene expression and represent a new class of regulatory RNAs distinct from canonical snoRNAs.Also watch the Video Abstract. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Distant Encounters:The Prometheus and Phaethon Episodes in the Argonautica of Apollonius RhodiusCalvin S. ByreOn several occasions in Apollonius Rhodius' Argonautica, the Argonauts casually encounter figures from other myths or from the divine world. These incidents do not affect the further development of the plot, and there is typically no communication or interaction between the two parties of the encounter.1 Thematic and structural parallels suggest that two of these encounters (...) form a pair. Both concern the punishments inflicted upon a mythological figure by Zeus, and by their placement they serve as a sort of frame around the Colchian portion of the poem. The first occurs in 2.124659, when the Argonauts sail within view of the crags of the Caucasus as they draw near to Colchis. There, they catch sight of the eagle that torments Prometheus, and they hear the Titan's cries of agony. The second occurs in 4.596626, shortly after Jason and Medea, in possession of the Golden Fleece, have killed her brother Apsyrtus in order to free the Argonauts from pursuit by him. Sailing on the river Eridanus, the Argonauts come near the place where nauseous vapors emanate from the smoldering body of Phaethon, who had been blasted from the chariot of Helios by a thunderbolt and had fallen into the outfall of a nearby lake.Guido Paduano has recently sought to explain the rather haunting effect of the Prometheus and Phaethon episodes as the result of the suspension of the fixed regularity of the temporal framework within which most of the events of the Argonautic expedition take place: the Argonauts confront a distant, mythic past that impinges upon the present, and experience something of the perdurability of the mythic figures' pain and suffering ("Apparenze" 166-69). But Paduano does not take into account the poet's handling of point of view in these episodes: the systematic contrasts between the information that the narrator gives his audience about the scenes and what the Argonauts themselves perceive and know about them. These contrasts, I believe, are central to our understanding of the effect of the two episodes. [End Page 275]The Prometheus episode, as Hermann Fränkel observed (Noten 318), is presented from two alternating points of view. In the more precise terms of contemporary narratology, there are alternating "focalizers" in the episode.2 Lines 124647 are a case of what de Jong (Narrators 102-18) would call "explicit embedded focalization": the narrator tells us that the Argonauts themselves see the inmost part of the Black Sea and the steep crags of the Caucasus come into view. Lines 124850 are focalized by the narrator: in an authorial comment apropos of the Caucasus, he tells how Prometheus, bound there with bronze fetters, feeds an eagle with his liver. Lines 125153 are again focalized by the Argonauts, telling how they see () the eagle flying above the ship, near the clouds, making the sails flap by its passage. Lines 125455 are, in Fränkel's analysis, focalized by the narrator, who attempts to explain the fact that the eagle, high aloft, is able to move the sails of the ship; while lines 125659 return to focalization by the Argonauts, telling how they soon afterwards hear () the groans and lamentations of Prometheus as his liver is plucked, until they again perceive () the eagle returning from the mountain by the same way.There is nothing in the text to suggest that the Argonauts see Prometheus himself, nor that they can connect the cries and the eagle with him. Of the reactions of the Argonauts to what they see and hear we are told nothing. It may be, however, that lines 125455 do contain a hint of the thoughts and feelings aroused in the Argonauts: "for it did not have the nature of a bird of the air, but it moved the quillfeathers of its wings like wellpolished oars" ( [End Page 276] ).3 In the immediate context of the narrator's explicit report of the Argonauts' visual perceptions of the eagle in 125153, the comparison of the bird to a ship may be read as a case of what de Jong calls "assimilated" focalization; that is, the narrator may be... (shrink)

From immemorial time, many Tyrrhenian places of ancient Sicily and Italy were identified with the main stages of the return of Ulysses. Some Hellenistic critics assumed that it was from the various ancient and pre-Homeric myths that Homer drew inspiration, in the same way that he did with the myth of the Trojan War, which certainly occurred before him. Thus, the voyage of Ulysses, after his losing the course because of the storm at Cape Malea, had to be located in (...) those sites. But how can one explain the fact that Homer places the voyage from Circe to the Hades over the Ocean? Is it only a pseudogeographic poetic touch, aimed to magnify the exploit? Crates of Mallus did not think so: in his opinion, only some of the numerous adventures had taken place in the Tyrrhenian Sea, whereas Homer had purposefully placed some other exactly on the Atlantic Ocean, beyond the Pillars of Hercules. Whichever of the two models one chooses, the route of Ulysses seems to be completely unlikely, both from the point of view of objective reality and from the point of view of poetic imagination. It appears to be a senseless coming and going that takes the shape of some sort of a labyrinth. Furthermore, the navigation times suggested by the text do not accord at all with the distances among the real sites. For this reason, Eratosthenes held that, from Cape Malea onwards, Ulysses switched from the real world to that of fantasy, or better still to the world of some narrative fable that does not heed geography at all. The modern critics are inclined to agree with him and this thesis is nowadays the most popular one. Yet, a very serious objection can be raised here: the myth and the epos, are strictly linked to the geography and the topography as well – they are radically refractory to a narrative fable that totally contradicts the then realities of time and space. Why should Ulysses plunge from Cape Malea onwards straight into the Neverland kingdom? If we combine Odyssey’s data with those we can reconstruct for the earliest form of the Argonautic saga, then we get the solution that neither the ancient nor the modern critics have guessed correctly: up to around the middle of the 8th century B.C., the Greeks thought the Ocean to flow just after the Sicily Channel, essentially coinciding with the so-called Tyrrhenian Sea, still completely unknown at that time. This new perspective can well justify the objective disorder of Ulysses’ route. Above all, it also bears a deeper poetic sense: the Hero had the chance to know and to experience not only some far and exotic countries in general terms, but he also met the very boundaries of the surfacing lands and the rushing waters which encircle the terrestrial disc, bordering the external cosmic abyss. Ulysses came back home alive. He was able to tell the stories about the lands where no human being could ever sail. This borderline that geographically is clearly located marks at the same time the insurmountable chasm between the physical and the meta-physical world. (shrink)

De fato 35 is part of Cicero's argument against the Stoic theory of causation. He claims in general that the Stoic chain of causes consists of antecedent but not efficient causes. To the examples cited in the previous chapter he adds verses from the opening of Ennius’ Medea exul (lines 208–11 Jocelyn = FRL 2 and TRF 89.1–4) containing the Nurse's lamentation over the origins of the Argonautic expedition that led, ultimately, to Medea's current mental distress. Then follows the question (...) quorsum haec praeterita? and the answer quia sequitur illud, ‘nam numquam era errans mea domo ecferret pedem | Medea, animo aegro, amore saeuo saucia’, non ut eae res causam adferrent amoris, citing Ennius, Medea exul 215–16 Jocelyn = FRL 2 and TRF 89.8–9. Editors and commentators have struggled to explain the relation of the answer to the question. Here it is argued that the relation becomes clear if one adopts non for non and punctuates with a query after amoris. The sense will be: ‘Why have these past events been cited? In view of the sequel … was it not so that they bring on the cause of love?’ In other words, the Nurse, like the Stoics in Cicero's view, cites antecedent events as if they were efficient causes. (shrink)

Nietzsche a découvert un continent, celui de la Volonté de Puissance - et nous l'avons perdu. Délibérément, consciencieusement perdu, avec un acharnement à la mesure de l'effroi qu'il nous inspire. Car nous n'aimons pas savoir qui nous sommes, nous n'aimons pas marcher à visage découvert, la poitrine nue, vêtus de notre seul courage ; en bons pharisiens, en bons démocrates, en bons hypocrites, nous nous glissons le long des murs, furtivement, le dogme dans la ceinture, pour assassiner à coups de (...) morale, de religion ou de philosophie les hommes exceptionnels, les héros de la pensée, les Argonautes de l'avenir. Nous voulons la bonne, la confortable chaleur du troupeau et nous bêlons de peur sous la cruelle et impitoyable lumière de Nietzsche. Pareils à de vieux hiboux dépenaillés, nous clignons des yeux, dérangés dans notre nocturne retraite. L'Homme suppose un être qui n'existe pas encore, mais qui est la fin de son existence. (shrink)

The third part of the article is focused on the interpretation of a well-known poem by Zbigniew Herbert, “The Message of Mr. Cogito”. The rhetorical figure, the golden fleece of nothingness, has been interpreted in the context of Meister Eckhart’s apophatic theology, as well as the phenomenology of Bertrand Welte. Since nothingness has been described by the predicate of the golden fleece, it paradoxically comes across as something that is. The golden fleece, in turn, alludes to the ancient Greek poem (...) by Apollonius of Rhodes, in which it became a reward for the Argonauts’ virtue of courage in their fight against evil. In the ancient myths of Hellas, the golden fleece is also a symbol of divine providence and protection. Therefore nothingness, described in the poem by the predicate of the golden fleece, does not have to mean non-existence, or mere nothing, but it can point to reality which transcends the limits of human language and as such, it can be described merely in the terms of apophatic theology. For B. Welte, on the other hand, nothingness exists in the consciousness of Dasein as the inevitability of death and its ontological status is ambiguous. This is because nothingness exists as something that is. Since Dasein intends to endow his/her being-here with meaning by following the rules of ethics, the only guarantee of their rightfulness is nothingness understood as the mystery of transcendence. (shrink)

Un tipo de prolepsis, utilizado frecuentemente en Argonáuticas, es el discurso-programa en el cual un personaje anticipa la narración posterior. De esta manera funciona el relato de Fineo como guía de navegación para los Argonautas. Con el ineludible modelo de los relatos de viajes de Odisea, esta narración interna guarda una relación especular con la obra que la contiene y conlleva una cuasi-identificación entre narrador interno y narrador principal. Este artículo tiene como objetivo el análisis de los niveles narrativos en (...) este relato, para mostrar el modo en que esa técnica anticipatoria funciona en el poema en un nivel metaliterario. One type of prolepsis, frequently used in the Argonautica, is the programmatic speech in which a character anticipates the subsequent story. In this manner works the story of Phineus as navigation guidance for the Argonauts. With the inevitable model of travel stories of Odyssey, this internal narrative keeps a mirror-relationship with the work that contains it and carries a quasi-identification between internal narrator and main narrator. This article aims to analyze the narrative levels in this story, to show how this anticipatory technique works in the poem on a metaliterary level. (shrink)

The Argonautica of Apollonius Rhodius deals with a band of heroes one generation before the great warriors at Troy, and the narrative does not really concern itself directly with the later generation. Some of the familiar heroes of Homer may never seem very far from Apollonius' narrative, but they tend not to appear in the poem themselves. One who does is Achilles, twice in fact: once in the first book and once in the last. Both of these passages deal with (...) his early life: the first when he is in the care of Chiron and his wife , the second when he is in the family home with Peleus and Thetis . In the former the gods of heaven and nymphs of Pelion are described as watching the departure of the Argo from Thessaly bound for Colchis. Chiron then comes down from Pelion and waves the heroes goodbye. His wife meanwhile holds Achilles on her arm and shows the child to his father Peleus as he departs with the Argonauts. The later passage describes the failed attempt of Thetis to make her son immortal. In this account Thetis addresses Peleus for the first time since their separation , and then vanishes into the depths of ocean. Their separation occurred some time earlier when she disappeared in anger after her failure to make the young Achilles immortal. She tried to do this by placing him in the fire during the night, and anointing him with ambrosia during the day :The attempt fails when Peleus happens to see his son's immersion in the flames, and gives out a terrible cry, whereupon Thetis throws the boy down, goes away herself, and does not return. (shrink)

Dans le 4e livre de sa Chronique du monde, Jean Malalas décrit l'histoire du lieu de pèlerinage de l'archange Michel à Anaplous près de Constantinople. Cette histoire comprend deux parties dont la première relate la construction d'un temple par les argonautes qui rebaptise la place Sosthenion c'est-à-dire la place du salut et dont la seconde parle de la visite du site par Constantin qui aura la révélation de l'identité de la statue de Michel à travers un rêve. Pour l'A. ce (...) récit a une signification réelle au sein de l'oeuvre idéologique de la Chronique. Le lieu de pèlerinage se place dans la continuité de l'histoire du salut instaurée par le Christ et s'élargie sous l'empereur Constantin. Celui-ci joue un rôle essentiel dans la rédemption du sanctuaire païen de Sosthène : l'épisode de son rêve préfigure sa conversion. (shrink)

While it is no secret that Valerius Flaccus’Argonauticaexplores civil-war themes at great length, the conflicts arising on the island of Peuce between the Colchians and the Argonauts and within the Argonautic party itself in the epic's final book (8.217–467) have been overlooked in critical studies of Valerian civil war. This article argues that Valerius presents the conflicts on Peuce as examples of civil war—emphasizing the bonds of kinship between the conflicting parties and illustrating effects of this discord using imagery of (...) stasis and cosmic dissolution associated with civil war in the wider Latin literary tradition—and thus invites reflection on the development and manifestation of internecine strife within theArgonautica. (shrink)

In a collaborative work situation at a distance, the use of avatars to represent collaborators reduces collaborative effort. Also, animated avatars can help distant users to ground their relationship and facilitate their interaction because they materialise visual clues for the distant collaborators and their current activity. To check the validity of these hypotheses we set up an experiment based on the use of a collaborative virtual environment (CVE) synchronised for collective medical decision-making. Several teams of practitioners from different disciplines will (...) be required to deal with liver tumours displayed in Argonaute 3D. In this paper, we provide some evidence from existing studies for the hypotheses and select several measures to estimate the grounding process in CVEs. Next, we briefly describe the setup used to collect observable data with Argonaute 3D and we summarise first observations acquired with practitioners. (shrink)

Les cartes donnent souvent l’impression que le monde est saturé et que la surface de notre fragile planète a renoncé à la dimension du mystère. Ce sentiment d’accomplissement est trompeur. Il est le propre de la modernité occidentale. Tout au long de son histoire, l’Occident n’a eu cesse d’affronter les espaces ouverts pour les transformer en lieux clos sans que ce verrouillage eût jamais été décisif. Tant mieux, car, à chaque fois qu’il rouvre sur un horizon nouveau, le monde suscite (...) l’éblouissement. Les Argonautes et Ulysse ont connu cette sidération, de même que Christophe Colomb à sa manière. L’art du lienzo aztèque, les lignes de chant des Aborigènes australiens et la cartographie extrême-orientale confirment que l’Occident ne détient pas le monopole de la vision géographique du monde. Et plutôt que de réserver les océans aux seules caravelles de Colomb, on lancera aussi dans l’aventure Abou Bakari II, empereur malinké, et Zheng He, amiral chinois. Ces tours et détours à travers espaces et lieux d’hier et d’aujourd’hui postulent l’existence d’un monde plausible qui sonnerait le glas des revendications hégémoniques de l’Occident. (shrink)

At the intersection of literature and history, three “antique romances” initiated a new genre in the mid-twelfth century by transposing into French the great stories of Greek and Latin epic: the fratricidal war of Oedipus's sons in the Roman de Thèbes, the founding of Rome in the Eneas, and the Roman de Troie's Trojan War based on Dares and Dictys. Rejecting Homer's version for these “eyewitness” accounts, Benoît de Sainte-Maure translated the full history of the Trojan War from its beginning (...) in the tale of Jason and the Argonauts to the annihilation of Troy and the victors’ unhappy homecomings. The myth of Trojan descent claimed by many European rulers, including the British and Normans, gives Benoît's translation more than entertainment value for his first public, the Plantagenêt court of Henry II and Eleanor of Aquitaine. Indeed, while repeatedly assuring his readers that this great estoire, story and history, will provide pleasurable enjoyment, Benoît also signals a more serious intent by invoking Solomon and the seven liberal arts: we would be like beasts if not for learning from the past that allows us to distinguish between wisdom and folly. The author/narrator's school training is on full display as he highlights the importance of remembering and the dangers of forgetting. Obliged to share his knowledge, Benoît will put into romanz matter that is at once old and new, lost and refound, so that lay readers without access to his Latin sources can “remember” their past as he shapes it in romance. The success of his enterprise can be gauged by the number of extant manuscripts as well as the romance's subsequent influence on multiple versions of Trojan history, from the Histoire ancienne jusqu’à César to Chaucer's Troilus and Criseyde. But can we pinpoint more specifically what and how Benoît's public might remember? (shrink)

AtArgon.4.1653–88, Medea steps forward among the Argonauts and asserts that their harbourage on Crete will not be blocked by the bronze giant Talos, who stands menacingly throwing rocks at their ship. She claims that she alone can subdue him, and then steps forward and proceeds to do so. Using a sequence of ‘magical’ ritualistic acts, she causes Talos to scrape his vulnerable heel on a rock and fall down dead, as the ichor pours from his wound. This scene is the (...) last in which Medea appears in the epic, and accordingly it forms the final opportunity to bridge the gap between the Medea of theArgonauticaand the future Medea, one whose actions are already well known from such works as Pindar's fourthPythian Odeand Euripides’Medea. The importance for Apollonius to create a plausible transition between the Medea of earlier myth and the Argonautic Medea is evident. A clear-cut break from tradition would allow Medea to become an alternative Medea, perhaps akin to the alternative portrayal of Helen by Euripides; a continuation would allow corroboration with earlier sources, which would lend authority and validation to Apollonius’ version. It is now the common consensus that Apollonius tried, however successfully, to bridge the gap between a young and an adult Medea and between tradition and innovation in her character. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:The War with God: Theomachy in Roman Imperial Poetry by Pramit ChaudhuriMartin T. DinterPramit Chaudhuri. The War with God: Theomachy in Roman Imperial Poetry. Oxford: Oxford University Press, 2014. xvi + 386 pp. Cloth, $74.We are all fighting our own demons, but some of us—so Chaudhuri tells us—are even fighting our own gods. Accordingly, a wide range of theomachs and their representation in classical literature fills the ranks (...) of this excellent book that will certainly elbow its way onto Mt. Olympus to sit comfortably next to divine Feeney (1991 and 1998) and sublime Hardie (1986 and 1993). Indeed, Chaudhuri transcends the scope of Feeney (1991) by including not only Senecan (and Attic) tragedy but also texts and contexts ranging from panegyric to philosophy and from lyric to historiography.Chaudhuri’s book falls into three parts. Its first three chapters cover theomachy in Greek poetry (Homer and Attic tragedy), as well as the development of theomachy in Augustan epic, with chapters on Lucretius and Vergil and Ovid. Here, Chaudhuri introduces some of the main patterns and contexts that will be developed in later imperial poetry. Chaudhuri also states clearly what will not be covered here at length: the voyage myths of the Odyssey and the Argonauts, Aristophanes’ Birds, and the (pseudo-) Aeschylean Prometheus Bound. Part 2 covers Neronian literature with Seneca’s Hercules Furens and Lucan, while Part 3 focuses on the Flavian era, with Silius and Statius. Statius’ Capaneus forms a highpoint amongst the theomachs and thus deservedly receives extra attention. Chaudhuri rounds off the Flavian section with a chapter on the politics [End Page 177] of theomachy, in which he samples theomachy as a trope for the confrontation between subject and ruler, ruler and god, rival emperors and the confrontation of dynasties. After all, the Flavian poets had witnessed the principate develop over time, the struggles for the throne, and the rise and fall of dynasties. This is followed by a titillating epilogue showcasing how the themes developed in the previous chapters that breach the divide between mortal and immortal (such as fame, equanimity, skepticism, and poetic and imperial apotheosis) echo through the centuries. Rarely, however, do we find simple didactic moralism. Instead, “the theomach is instrumental in generating a dialogue on the broader symbolism of fighting the gods, its stakes and implications” (323). Chaudhuri can but hint at the rich afterlife of the theomach across Europe from the fifteenth to the seventeenth centuries, a subject that would fill a second volume. He nevertheless whets the reader’s appetite by pointing to Milton’s Paradise Lost and Samson Agonistes, Ariosto’s Orlando Furioso, Christopher Marlowe’s Tamburlaine, Dante’s Inferno, and Tasso’s Gerusalemme Liberata, as well as a host of epigraphs to each chapter, and concludes with a glance at the twentieth and twenty-first centuries with Philip Pullman’s His Dark Materials, Richard Dawkins versus God, and modern physicists’ search for a God particle.Chaudhuri sets the volume off by contrasting theomachy with gigantomachy. While the feats of the Giants “remain far distant in time from the activities of humankind … the theomach speaks the language of humanity … offering a richer context for his radical aspirations and … inviting the audience to adopt an alternative view on the theological status quo” (5). He also places theomachy in its cultural context when he follows Momigliano’s (1984) suggestion that under Augustus poetry replaced antiquarianism and philosophy as the primary genre in which to think about the gods. The figure of the contemptor divum (despiser of the gods) thus comes to embody the contrast between piety and impiety which itself is grounded in the empirical basis of Roman religion. But rather than testing methods of communication with the divine, as the Romans so often did with divinatory practices and ritual protocols, the contemptor divum tackles the question of whether it is possible to know the divine at all and whether the gods even exist. “By placing these conflicts at the heart of their works, the epic poets expanded the cultural conversation to include the testing of the divine in the Romans’ attempts to make sense of the epistemological, theological, and political concerns pertaining... (shrink)

Le premier document présenté est inédit : c'est un lécythe attique à figures rouges du début du Ve s. av. J.-C. décoré d'un Éros tirant à l'arc, premier exemple d'un type iconographique promis à une grande fortune. Ensuite est examinée la scène figurée sur le col d'un cratère à figures rouges trouvé à Olynthe : elle doit représenter Héphaistos essayant en vain de se venger des Dioscures après la mise à mort du géant de bronze Talos, épilogue jusqu'alors inconnu d'une (...) des aventures des Argonautes. On revient enfin sur l'inscription ID 2548 et l'identification du Dioskourion de Délos : les fragments d'un kouros archaïque et d'un kouros archaïsant trouvés dans la cella du « temple A » de GD 123 sont presque certainement les restes des xoana évoqués par l'inscription, et l'identification du sanctuaire avec le Dioskourion est donc pratiquement assurée. (shrink)

Catullus' use of nutrices for the Nereids' breasts in line 18 of Poem 64 is not perhaps the most important problem in the poem, but it is not without interest and may have significance beyond its narrow context. This ‘weird preciosity’ has been integrated into a wider reading by Francis Cairns, who interestingly drew attention to Artemidorus 2.37–8 where to dream of Aphrodite emerging from the sea and naked as far as the ζώνη is a good omen for sea-travellers because (...) her breasts are τροΦιμώτατοι. So too, to dream of Nereids and Amphitrite is also a good omen. Cairns linked this passage to the persistent connections of Aphrodite and the Nereids with marriage, concluding that the Argonauts are presented with a very good omen as they set out and as the prospective bride and groom, Peleus and Thetis, meet. Cairns naturally finds support here for what we might call the ‘positive’ view of Catullus' heroic age, a view now apparently in the ascendant after the doubts created by John Bramble's well-known paper. Problems remain of course – Catullus 64 is not a dream – and the purpose of the present note is to keep debate alive by calling attention to a rather different set of considerations which complicate, rather than undermine, Cairns' reading. (shrink)

It is well established that microRNAs (miRNAs) induce mRNA degradation by binding to 3′ untranslated regions (UTRs). The functionality of sites in the coding domain sequence (CDS), on the other hand, remains under discussion. Such sites have limited impact on target mRNA abundance and recent work suggests that miRNAs bind in the CDS to inhibit translation. What then could be the regulatory benefits of translation inhibition through CDS targeting compared to mRNA degradation following 3′ UTR binding? We propose that these (...) domain‐dependent effects serve to diversify the functional repertoire of post‐transcriptional gene expression control. Possible regulatory benefits may include tuning the time‐scale and magnitude of post‐transcriptional regulation, regulating protein abundance depending on or independently of the cellular state, and regulation of the protein abundance of alternative splice variants. Finally, we review emerging evidence that these ideas may generalize to RNA‐binding proteins beyond miRNAs and Argonaute proteins. (shrink)

When Apollonius' Argonautica began to reemerge as an epic worthy to be read as a classic in its own right in the 1960s and following, scholarly interest focused largely on topics such as the nature of the hero, narrative technique, limited scholarly audience, realism, the poem's engagement with archaic, classical, and contemporary texts, and its reception among later writers. In the 1990s, scholars began to examine the rehabilitated epic for evidence of possible engagement with contemporary political and cultural issues. Thalmann's (...) new monograph builds upon this productive trend, offering a detailed analysis of the "space" defined by the Argonautic journey, "the medium through which it raises and probes those cultural questions". Cultural geography and anthropology inform the author's analytical method, according to which "human cultures do not just use space but produce it and are shaped in turn by it". (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Creating Life: The Aesthetic Utopia of Russian ModernismJohn GoodliffeCreating Life: The Aesthetic Utopia of Russian Modernism, edited by Irina Paperno and Joan Delaney Grossman; x & 288 pp. Stanford: Stanford University Press, 1994, $39.95.In describing the history of a country’s literature, one may well be tempted to divide it into separate compartments and so lose sight of the continuity which is, in the final analysis, more worthy of (...) attention. Historians of Russian literature have often succumbed to this temptation and it became almost commonplace to read that in Russia the Realism of the nineteenth century gave way to the Symbolism which began in the twentieth; that Symbolism gave way to Futurism; and that in due course all the earlier “-isms” were swept aside by the Socialist Realism of the Soviet period. For Marxist-oriented Soviet [End Page 371] historians such preoccupation with compartmentalization was obsessive. This makes more than welcome a series of essays which is at pains to emphasize the essential connections and kinship between these various “-isms.”Four of the seven essays are intended to demonstrate how the Symbolists, while ostensibly breaking with the earlier tradition of positivism (the idea that art’s essential purpose is to help build a better world), were, in a number of important respects, continuing and even reinforcing what they claimed to despise. Thus, regarding art and life as indissolubly linked, they attempted to turn life into art and art into life. Their endeavors frequently led them into behavior that now appears “eccentric, at times even ridiculous” (p. 166). Olga Matich describes how Blok, Bely, Dmitry Merezhkovsky, and Zinaida Gippius attempted to model their sexual relationships on the pattern of the “erotic utopia” described by Vladimir Solov’ev in his seminal The Meaning of Love (1892–94). Joan Delaney Grossman discusses Nina Petrovskaia’s relationships with Bely and Valery Briusov. Michael Wachtel shows how Viacheslav Ivanov attempted to overcome his grief at the death of his first wife by using his creative powers to make contact with her “beyond the grave.”Irene Masing-Delic traces the Pygmalion myth through Pushkin, Baratynsky, Turgenev, and Chernyshevsky to the Symbolists who were especially attracted by a myth which showed how an artist could create life and even conquer death. In “Andrei Bely and the Argonauts’ mythmaking,” Alexander Lavrov considers the role of the “Argonaut” circle in establishing a Russian Symbolist culture in the first years of the twentieth century. The Argonauts’ credo was “life-creation” rather than “art-creation,” and they claimed to make no distinction between “talent for living” and “talent for writing.” Lavrov argues that the failure of the relationship between Bely and Nina Petrovskaia marked the disintegration of “Argonautism” and the culture they sought to create. It is left to Irina Gutkin in the concluding essay to guide us through the grotesqueries of Futurism into the apparently diametrically opposed, sanitized world of Socialist Realism, by way of Constructivism, Marxism, and Meyerholdian bio-mechanics, leaving us in little doubt that, appearances to the contrary, each of these movements was concerned with turning art into life and using it to create a better world. So ultimately, as she neatly sums up the thesis of the whole collection, “The aesthetic utopian ideal of art creating life, which took shape at the beginning of the twentieth century, was fused with the utilitarian tradition of the 1860s” (p. 181).I have deliberately reserved for the end comment on Irina Paperno’s introduction and opening article (“The Meaning of Art: Symbolist Theories”) in order to emphasize the manifest contribution she and her co-editor, Joan Delaney Grossman, have made to ensuring the coherence of this admirable collection. Professor Paperno’s clear and concise coverage of her topics makes it evident that she was determined that the book should not turn into the kind of bits-and-pieces patchwork that too many publications of this sort tend to [End Page 372] become without a firm editorial hand at the helm. Her earlier book on Chernyshevsky (Chernyshevsky and the Age of Realism, 1988) and Irene Masing-Delic’s Abolishing Death; a Salvation Myth of Russian Twentieth-Century Literature (1992), form the first two parts of... (shrink)