The behaviour and roles of the microtubule network and the microfilaments following fertilization in the mouse oocyte are described. The microtubule network is organized by multiple microtubule organizing centres (MTOCs) and these play a major role in establishing spindle structure and pronuclear movement following fertilization; in contrast to sea urchin and frog eggs, the sperm centriole plays little part in organization of the post‐fertilization spindle. The microfilaments are required for spindle rotation, polar body formation, certain changes in the egg cortex, (...) and also for pronuclear movement. Influences of the chromosomes on microtubule and microfilament organisation are also discussed. (shrink)

The scholastic philosopher is interested in definition for a different reason than the lexicographer and linguist. The philosopher is trying to learn things. Fe defines, after investigating reality, in an attempt to describe reality clearly and to sum up some aspect of his understanding of reality. Hence, we find our scholastic philosophers adopting as a main feature of their method this insistence on defining, on precise and detailed explanation of their definitions, and on proving that their definitions da correctly express (...) what a nature or activity is. A dictionary of the language of scholastic philosophy fitted to the needs of beginners and of undergraduate students of the subject is not available in English. (shrink)

This edition includes, in addition to the most pertinent sections of The Fable's two volumes, a selection from Mandeville's An Enquiry into the Origin of Honor and selections from two of Mandeville's most important sources: Pierre Bayle and the Jansenist Pierre Nicole. Hundert's Introduction places Mandeville in a number of eighteenth-century debates--particularly that of the nature and morality of commercial modernity--and underscores the degree to which his work stood as a central problem, not only for his immediate English contemporaries, but (...) for such philosophers as Hume, Rousseau, and Kant. The selections are substantive enough to faithfully represent Mandeville the social theorist, and compact enough to be used in courses that can afford to spend no more than a week on his work. (shrink)

Anderson and Csima :245–264, 2014) defined a jump operator, the bounded jump, with respect to bounded Turing reducibility. They showed that the bounded jump is closely related to the Ershov hierarchy and that it satisfies an analogue of Shoenfield jump inversion. We show that there are high bounded low sets and low bounded high sets. Thus, the information coded in the bounded jump is quite different from that of the standard jump. We also consider whether the analogue of the Jump (...) Theorem holds for the bounded jump: do we have A≤bTB\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$A \le _{bT}B$$\end{document} if and only if Ab≤1Bb\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$A^b \le _1 B^b$$\end{document}? We show the forward direction holds but not the reverse. (shrink)

The network is moving towards a global informational equilibrium that is irrevocable – if inter‐individual communication persists as the only driving force behind the network's evolution. On the basis of an example, this chapter compares the respective changes in the values of the main characteristic variables at the level of the network as a whole, and that of each cluster considered separately. Any local informational equilibrium achieved by a cluster is therefore fundamentally unstable, as it is constantly threatened by such (...) a phenomenon. It follows that the cumulative formation of local clusters of actors corresponding to a progressive regionalization of the effective space of the network is then erased as at least one category shared by all actors allows each of them to escape from the cluster in which they would otherwise remain enclosed. Maintaining separations between regions dividing the network space before the homogenization process ends means that it does not only have advantages. (shrink)

Voir son cerveau en première personne s’activer à l’occasion de la réalisation d’une tâche semble établir plus qu’une corrélation en décrivant ce qui serait un lien de causalité entre le corps et son cerveau. Le corps est une surface et un résultat dont la conscience ne perçoit le processus vivant qu’en retard sur la vitalité et la mobilité du cerveau. Nous sommes en retard sur notre cerveau mais notre conscience du présent ne peut avoir accès à la temporalité de sa (...) condition. La transparence du cerveau in vivo implique des dispositifs neuro-expérientiels. (shrink)

The specter of epistemic closure haunts current epistemology: some regard the refutation of closure as obvious, while others take its denial to be an epistemicoutrage. To some extent, the strong difference of opinion has its source in certain misapprehensions. This paper tries to formulate and clarify the key issues dividing the two sides and contends that, in certain respects, the difference between the friend and the foe of closure may be more a matter of semantics than substance. The paper goes (...) on to argue that once the substantial issues have been properly formulated, there is a limit to how far deductive reasoning can take the parties to the dispute. (shrink)

Contemporary physics, especially quantum theory, has raised profound questions about the relationship between the methods of science and the reality these methods seek to investigate. D'Espagnat investigates these questions as well as how we should answer them. Part I examines the practices of contemporary physicists and addresses the criticism philosophers of science have made of these practices. The doctrine of physical realism, adopted by most physicists and many philosophers of science, comprises Part II. Part III explores the consequences of physical (...) realism for our understanding of what science can seek to know of reality, and concludes by outlining the position contemporary physics indicates we should take. (shrink)

_Nulla dies sine linea_ « Regarde de tous tes yeux, regarde » « Travaille ton instrument » Essentielle à toute activité artistique, la pratique d’exercices est pourtant rarement interrogée en tant que telle. Qu’est-ce qu’un exercice artistique? Quelles perspectives la pensée de l’exercice permet-elle d’ouvrir sur la compréhension des pratiques artistiques, sur leurs liens avec les savoirs et les techniques, sur leur dimension historique et sociale, sur les valeurs de transmission qu’elles font vivre? Réactivée dans la philosophie contemporaine, la notion (...) d’exercice n’est pourtant que rarement confrontée aux pratiques artistiques et aux élaborations théoriques de ces pratiques. Or l’artiste, c’est d’abord une femme ou un homme qui, pour faire et pour produire, doit s’exercer, et s’exercer sans relâche. Exercices d’apprentissage et de formation, antérieurs à l’œuvre ; e... (shrink)