A summation of the work of one of the most influential and provocative interpreters of science, it aims at saving what is good and valuable in modernity and ...

In a letter addressed to Mercator in 1558, John Dee made an odd announcement, describing the Portuguese mathematician and cosmographer Pedro Nunes as the ‘most learned and grave man who is the sole relic and ornament and prop of the mathematical arts among us’, and appointing him his intellectual executor. This episode shows that Dee considered Nunes one of his most distinguished contemporaries, and also that some connection existed between the two men. Unfortunately not much is known about this connection, (...) and even such basic questions such as ‘What could John Dee know about this Portuguese cosmographer’s scientific work?’ or ‘When, why and where did this interest come about?’ still lack proper answers. In this paper I address this connection and examine Nunes’ influence on Dee’s mathematical work. I argue that Dee was interested in Nunes’ work as early as 1552 . I also claim that Dee was aware of Nunes’ programme for the use of mathematics in studying physical phenomena and that this may have influenced his own views on the subject. (shrink)

Today's physics has led to incredible advances in the technology we use in daily life - from cell phones and GPS systems to PET scans and more. Current theories in physics have been amazingly effective in practical terms. Yet all is far from well: the two foundational concepts in physics - Quantum Theory and General Relativity - are incompatible with each other, and observations of the universe show that our theories are incomplete - at best. While physicists have tried to (...) paper over this impasse by inventing dark matter and dark energy, they remain unobserved mysteries. Adding fuel to the fire of current crises, artificial intelligence threatens to replace our most cherished theories and procedures with arcane algorithms. Worse yet perhaps, the public understands physics poorly, either taking it for granted or fearing and rejecting it completely. Physicists dream of a new universal theory that will completely change how we see our world, much as Einstein did with relativity and Newton with gravity. Likewise, society loves the romantic notion of a single genius heroically creating a massive paradigm shift. Still, is this scenario likely today? Perhaps the next steps in physics will be incremental rather than gigantic. In Physics in Crisis, Bruno Mansoulié uses simple language, insightful examples, and his personal experience as a working physicist to address these fundamental questions and reflect on how today's crises in physics might be solved. (shrink)

The use of forward models is well established in cognitive and computational neuroscience. We compare and contrast two recent, but interestingly divergent, accounts of the place of forward models in the human cognitive architecture. On the Auxiliary Forward Model account, forward models are special-purpose prediction mechanisms implemented by additional circuitry distinct from core mechanisms of perception and action. On the Integral Forward Model account, forward models lie at the heart of all forms of perception and action. We compare these neighbouring (...) but importantly different visions and consider their implications for the cognitive sciences. We end by asking what kinds of empirical research might offer evidence favouring one or the other of these approaches. (shrink)

O filósofo sul coreano Byung-Chul Han em seu ensaio Agonia do Eros, procura compreender como as relações advindas do mundo digital impedem o erotismo de se desenvolver e quais são as consequências nefastas nas relações afetivas em que o ego narcísico sobressai no lugar do amor.

SummaryMutations in human genes encoding transcription factors are often dominant because one active allele cannot ensure a normal phenotype (haploinsufficiency). In other instances, heterozygous mutations of two genes are required for a phenotype to appear (combined haploinsufficiency). Here, we explore with models (i) the basis of haploinsufficiency and combined haploinsufficiency owing to mutations in transcription activators, and (ii) how the effects of such mutations can be amplified or buffered by subsequent steps in a transcription cascade. We propose that the non‐linear (...) (sigmoidal) response of transcription to the concentration of activators can explain haploinsufficiency. We further show that the sigmoidal character of the output of a cascade increases with the number of steps involved, the settings of which will determine the buffering or enhancement of the effects of a decreased concentration of an upstream activator. This exploration provides insights into the bases of compensatory mutations and on interloci interactions underlying oligogenic inheritance patterns. (shrink)

The economic crisis happening across the world over the last few years describes a range of interdependencies and interactions,and has highlighted the fundamentalf laws of neoclassical economic theory: its unedifying focus on prediction and, above all, its inability to explain how the economy really works. As such, it is increasingly recognised that economic phenomena cannot be exclusively investigated as being derived from deterministic, predictable and mechanistic dynamics. Instead, a new approach is required by which history-dependence, organic and ever-evolving processes are (...) also accounted for. As this view implies new challenges and opportunities for policy, we will focus our attention on innovative components of Complexity Theory for the study of economics and the evaluation of public policies. (shrink)

The French and German political economies have been significantly reconfigured over the past two decades. Although the changes have often been more piecemeal than revolutionary, their cumulative effects are profound. The authors characterize the changes that have taken place as involving the institutionalization of new forms of dualism and argue that what gives contemporary developments a different character from the past is that dualism is now explicitly underwritten by state policy. They see this outcome as the culmination of a sequence (...) of developments, beginning in the field of industrial relations, moving into labor market dynamics, and finally finding institutional expression in welfare state reforms. Contrary to theoretical accounts that suggest that institutional complementarities support stability and institutional reproduction, the authors argue that the linkages across these realms have helped to translate employer strategies that originated in the realm of industrial relations into a stable, new, and less egalitarian model with state support. (shrink)

David Lewis’ Convention has been a major source of inspiration for philosophers and social scientists alike for the analysis of norms. In this essay, I demonstrate its usefulness for the analysis of some moral norms. At the same time, conventionalism with regards to moral norms has attracted sustained criticism. I discuss three major strands of criticism and propose how these can be met. First, I discuss the criticism that Lewis conventions analyze norms in situations with no conflict of interest, whereas (...) most, if not all, moral norms deal with situations with conflicting interests. This criticism can be answered by showing that conventions can emerge in those contexts as well. Secondly, I discuss the objection that this type of conventionalism, inspired by Lewis, presents moral norms as fundamentally contingent, whereas most, if not all, moral norms are not. However, such critics fail to appreciate that conventions are not radically contingent. Moreover, if one distinguishes the question as to why an individual should comply with a norm from the question whether the norm in question itself can be justified, a core element of the complaint of contingency disappears. The third objection to conventionalism concerns the way in which conventionalists justify norms. I argue that reflection upon the way in which according to Lewis norms are justified reveals a fundamental tension in his theory. Possible solutions to this tension all have in common that the complaint of contingency returns in some form. Therefore, this third complaint cannot be avoided altogether. (shrink)

Dès 1983, à l’occasion du colloque Une histoire des femmes est-elle possible? qui allait marquer le véritable départ de l’histoire des femmes en France, Alain Corbin soulignait la nécessité de se pencher aussi sur les « mentalités masculines », afin que puisse émerger une « histoire sexuée qui couple ses analyses ». L’auteur des Filles de noce resta longtemps peu entendu. Cette dernière décennie a pourtant vu une nette évolution s’amorcer, les masculinités françaises devenant peu à peu un ch...

The goal of this study is to characterize observers’ abilities to discriminate between endogenous and exogenous changes. To do so, we developed a new experimental paradigm. On each trial, participants were shown a dot pattern on the screen. Next, the pattern disappeared and participants were to reproduce it. Changes were surreptuously introduced in the stimulus, either by presenting participants anew with the dot pattern they had themselves produced on the previous trial or by presenting participants with a slightly different dot (...) pattern . We analyzed awareness of the changes and behavioral adaptation to them in a dynamical manner. We observe signal attenuation in the presence of endogenous change, dissociation between self-attribution reports and behavioral effect of agency. We discuss the source of this sensitive attenuation as well as the relation between a minimal or core self and an extended, narrative or autobiographical self. (shrink)

In the literature, Weak Kleene logics are usually taken as three-valued logics. However, Suszko has challenged the main idea of many-valued logic claiming that every logic can be presented in a two-valued fashion. In this paper, we provide two-valued semantics for the Weak Kleene logics and for a number of four-valued subsystems of them. We do the same for the so-called Logics of Nonsense, which are extensions of the Weak Kleene logics with unary operators that allow looking at them as (...) Logics of Formal Inconsistency and Logics of Formal Underterminedness. Our aim with this work, rather than arguing for Suszko’s thesis, is to show that two-valued presentations of these peculiar logics enlighten the non-standard behavior of their logical connectives. More specifically, the two-valued presentations of paraconsistent logics illustrate and clarify the disjunctive flavor of the conjunction, and dually, the two-valued presentations of paracomplete subsystems of Weak Kleene logics reveal the conjunctive flavor of the disjunction. (shrink)

Résumé Dans les Entretiens, Félibien dit d’Annibal Carrache qu’il a renouvelé la peinture après une phase de décadence en se tournant vers les grands maîtres du passé. Il postule ce faisant une continuité dans la signification des « parties » de la peinture comme le « dessin », le « coloris », l’« expression » etc. En réalité, il ne peut être question d’une continuité, du moins si les « concepts fondamentaux » de Woelfflin, qui distinguent d’une façon très radicale (...) les styles du XVI e et du XVII e siècle, ont un sens quelconque. L’étude détaillée du terme « dessein » (« disegno ») montre qu’il correspond à des réalités techniques très différentes chez Raffaël et Le Brun par exemple et que ce glissement dont les théoriciens du XVIIe siècle ne sont pas conscients produit une théorie de l’art, à caractère polémique et « académique », basée structuralement sur la méconnaisance. La « dispute du coloris»s’en ressent fortement. Cette méconnaissance intervient au moment même où la théorie de l’art prend un essor nouveau avec l’apparition du spécialiste d’art de profession, dont Félibien est lui-même un des exemples les plus saillants. (shrink)