Purpose: This study explores social networkers' interest in and attitudes toward personal genome testing (PGT), focusing on expectations related to the clinical integration of PGT results. Methods: An online survey of 1,087 social networking users was conducted to assess 1) use and interest in PGT; 2) attitudes toward PGT companies and test results; and 3) expectations for the clinical integration of PGT. Descriptive statistics were calculated to summarize respondents' characteristics and responses. Results: Six percent of respondents have used PGT, 64% (...) would consider using PGT, and 30% would not use PGT. Of those who would consider using PGT, 74% report they would use it to gain knowledge about disease in their family. 34% of all respondents consider the information obtained from PGT to be a medical diagnosis. 78% of those who would consider PGT would ask their physician for help interpreting test results, and 61% of all respondents believe physicians have a professional obligation to help individuals interpret PGT results. Conclusion: Respondents express interest in using PGT services, primarily for purposes related to their medical care and expect physicians to help interpret PGT results. Physicians should therefore be prepared for patient demands for information and counsel on the basis of PGT results. (shrink)

The first annual Alchemy Lecture brings four deep and agile writers from different geographies and disciplines into vibrant conversation on a topic of urgent relevance: humans and borders. Borders, Human Itineraries, and All Our Relation captures and expands those conversations in insightful, passionate ways. Architect, artist, and urban theorist Dele Adeyemo (UK/Nigeria) calls attention to the complexity of Black infrastructures, questioning how "the environments that surround us condition the possibility of our being." Poet Natalie Diaz (US/Mojave/Akimel O'otham) writes: "Like (...) story, migration is the sensual movement of knowledge," and asks, "What is the language we need to live right now?" Philosopher Nadia Yala Kisukidi (France) suggests there is no diasporic life "without the dynamics of fabulation, where we pass down, from generation to generation, the stories of our ancestors who walked barefoot for many months." And cultural theorist Rinaldo Walcott (Canada) asks us to consider inheritances beyond white supremacist logics: "What might it mean to live a life, if we can't risk desiring and working towards utopia?" As each Alchemist considers the legacies of anticolonial struggle, the future of the planet, and the textures of Black and Indigenous life, their essays speak to each other in multiple ways, creating something startling and revelatory: a vision of the world as it is, and as it could be. (shrink)

A 10 year-old child requires an esophagogastroduodenoscopy (EGD). One of the child’s parents is requesting an unsedated esophagogastroduodenoscopy, citing their experiences in a different country and concerns about anesthetic medications. The child is assenting to the procedure. The patient previously had multiple sedated EGDs without complications. Concerns are raised by the anesthesia, GI, and operating room teams about the ethics and child safety of performing an unsedated EGD, given this is not the typical standard of care at the performing hospital. (...) In this paper we analyze prior literature and ethical principles, and explore whether unsedated EGD with appropriate monitoring is an ethically acceptable alternative to sedated EGD in this instance. (shrink)

Over the past 20 years, organ donations in Spain have soared from modest numbers to the highest rate in the world. In the brief span between 1998 and 2005, donation rates have increased from 14 per million population to 35.1 p.m.p. By way of comparison the number in the United States is 25.5 donations p.m.p.

Positive emotions are highly valued and frequently sought. Beyond just being pleasant, however, positive emotions may also lead to long-term benefits in important domains, including work, physical health, and interpersonal relationships. Research thus far has focused on the broader functions of positive emotions. According to the broaden-and-build theory, positive emotions expand people’s thought–action repertoires and allow them to build psychological, intellectual, and social resources. New evidence suggests that positive emotions—particularly gratitude—may also play a role in motivating individuals to engage in (...) positive behaviors leading to self-improvement. We propose and offer supportive evidence that expressing gratitude leads people to muster effort to improve themselves via increases in connectedness, elevation, humility, and specific negative states including indebtedness. (shrink)

One of the most ancient art forms, poetry, like other art forms, finds its roots embedded in activities that are not necessarily associated with art today, most notably religious rituals. Still, even while poetry is now commonly enjoyed for its own sake, many poems continue to be made for specific life events: weddings, funerals, presidential swearing-in ceremonies, anniversaries, and so on. Their connection to such events may call into question the art status of some poems; indeed, definitions of poetry (as (...) is the case with definitions of art in general) must provide an account that establishes the art status of poems while still acknowledging that some poems may be parasitic upon human activities and events that have no intrinsically artistic goals. Questions of this sort already presuppose a notion of art that divorces art works from those activities and events and establishes art-making as an endeavor in its own right, one that by definition is independent from any other goals and one that, were it to be mixed with other activities or goals, would have its art status threatened. However, just as a notion of art that denied art status to (say) the Vietnam Memorial in Washington, DC in virtue of its serving a function beyond the purely artistic would be seriously defective, so a definition of poetry that denied poetry status to W. H. Auden’s ‘Funeral Blues’ would be anemic at best. The intention to write a poem, therefore, is the intention to fit one’s work into a tradition, one in which, as happens to be the case, poems are written for various occasions. Likewise, the poetic tradition is one in which various formal means have been employed (alliteration, meter, rhyme schemes, etc.); a ‘transparent’ poetic intention (i.e. one in which the poet is aware of the character of her intention) would therefore involve responding to the formal dimension of the tradition in various ways (see Ribeiro 2007). (shrink)

This paper is devoted to the study of some subvarieties of the variety Q of Q-Heyting algebras, that is, Heyting algebras with a quantifier. In particular, a deeper investigation is carried out in the variety Q subscript 3 of three-valued Q-Heyting algebras to show that the structure of the lattice of subvarieties of Q is far more complicated that the lattice of subvarieties of Heyting algebras. We determine the simple and subdirectly irreducible algebras in Q subscript 3 and we construct (...) the lattice of subvarieties lambda (Q subscript 3) of the variety Q subscript 3. (shrink)

We argue that estrogen feminization of the brain is the result of a series of events initiated by differential androgen exposure. There is no need to postulate a feminizing process parallel to androgen-induced masculinization to explain the findings.

Cano, Germán (2023)Mark Fisher: Los espectros del tardocapitalismoBarcelona: Gedisa, 149 p.ISBN 978-84-19406-00-2.

En su faceta de ensayista Edgar Allan Poe desarrolló interesantes ideas que corresponden al campo de la estética. Sin embargo, estas no han sido muy difundidas, y menos en América Latina, al contrario de su labor poética –mejor conocida–, y de su narrativa en prosa –que suele hacer parte de los programas de enseñanza de la literatura universal–. El presente escrito se propone recuperar algunos de sus planteamientos analizando su ensayo teórico “El propósito de la poesía”, siguiendo el rastro de (...) su crítica a una estética burguesa de masas y a una estética aristocrática tradicionalista. Con su lectura atenta rendimos un homenaje al autor, ahondando en su complejo perfil y siguiendo su exploración de temas tan variados como la crítica, el público, la recepción, la creación poética, la función del arte y la importancia social del poeta. Por último, su opinión sobre algunas figuras destacadas de la poesía mundial de su tiempo nos brinda un panorama muy rico del contexto cultural de la primera mitad del siglo XIX. (shrink)

Este trabajo tiene por objeto el estudio de la agravante de discriminación por razón de género recogida en el art. 22.4ª del C.P, por la Ley Orgánica 1/2015, de 30 de marzo. Nos vamos a centrar en el estudio del fundamento y elementos de la circunstancia agravante. Se prosigue, con el análisis de su compatibilidad con otras agravantes genéricas y su régimen de comunicabilidad a los partícipes del delito. Sin olvidar, el examen de las sentencias dictadas por el Tribunal Supremo.

Classic publishing of Eastern philosophy, religion, and poetry. This is a facsimile edition of the work originally published in London by John Murray in 1940.

Este estudio se define y articula a partir de la pregunta por el significado, sentido y estructura de la noción de “historia del pensamiento”, tal como ésta emerge y actúa desde los últimos pronunciamientos e intervenciones de Foucault, de un modo singularmente claro y revelador a partir de la primera versión del Prefacio a la “Historia de la sexualidad”, texto del que nos ocupamos con atención prioritaria a lo largo de este trabajo.

Este escrito muestra que el método que surge a partir del pensamiento cartesiano, con un propósito explicativo, revela una radical insuficiencia que conducirá a una nueva propuesta metódica que tiene ahora un propósito comprensivo: la hermenéutica. El método cartesiano se revela suficiente para comprender fenómenos de la naturaleza, pero se muestra insuficiente para hacerse cargo del fenómeno humano. Este método, originalmente orientado a la comprensión de textos, especialmente la escritura sagrada, con Schleiermacher se amplía para convertirse en un procedimiento de (...) comprensión de lo humano en general. This paper shows that the method emerging from Cartesian thinking, with an explanatory purpose, reveals a radical insufficiency that will lead to a new methodical proposal that has a comprehensive purpose: hermeneutics. The Cartesian method shows itself sufficient for the comprehension of natural phenomena, but it shows itself insufficientfor the human phenomena. This method—primarily oriented toward the comprehension of lexts. in particular Holy Scriptures— broadens in Schleiermacher's work so as to turn into a procedure for the comprehension of what is in general human. (shrink)

AbstractŁukasiewicz implication algebras are {→,1}-subreducts of Wajsberg algebras (MV-algebras). They are the algebraic counterpart of Super-Łukasiewicz Implicational logics investigated in Komori, Nogoya Math J 72:127–133, 1978. The aim of this paper is to study the direct decomposability of free Łukasiewicz implication algebras. We show that freely generated algebras are directly indecomposable. We also study the direct decomposability in free algebras of all its proper subvarieties and show that infinitely freely generated algebras are indecomposable, while finitely free generated algebras can be (...) only decomposed into a direct product of two factors, one of which is the two-element implication algebra. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:The Success and Malaise of CapitalismA Mimetic View of the MarketPablo Díaz-Morlán (bio)INTRODUCTIONThis article seeks to contribute to the knowledge that we have on the market as the central institution of capitalism, according to Girard's perspective. Mimetic theory (MT) can explain both the success and malaise caused by the market. Success is measured by the spread of desire, and malaise by the mimetic resentment caused by this spread of (...) desire.In 1979, Paul Dumouchel and Jean-Pierre Dupuy applied René Girard's mimetic theory for the first time to economics in their book L'Enfer des Choses.1 Both authors defended the need to advance toward the construction of a mimetic economic science placing at the center of the analysis the mimetic nature of the human being. They pointed out that the liberal conception of the individual as a being who makes decisions of maximum utility and autonomously is wrong. In short, the point was that the traditionally accepted homo economicus has been replaced with the homo mimeticus.2 In his contribution [End Page 275] to the book, "L'ambivalence de la rareté," Dumouchel establishes that scarcity emerges or is born as traditional bonds of solidarity are abandoned by members of a society that, until then, had ensured that everyone was assisted in case of need. In primitive human society, reciprocal bonds of solidarity prevailed. There was no scarcity, and this internal solidarity limited violence between the members of the group and expelled it to the outside. Scarcity was invented after the creation of the vicious cycle of individualism and the commercialization of social relations: a social institution established by the modern world after the solidarity mechanisms that protected the group against violence were abandoned.3 For both authors, the market arose as the institution that replaced the sacred, containing the violence, in both senses of the word "contain": On the one hand it held the violence within, and on the other it limited the violence.From its publication, L'Enfer des Choses was adopted as the founding treaty of the mimetic economy, even by Girard himself, who referred to it on several occasions when discussing economic issues.4 Both Dumouchel and Dupuy have gone into greater depth with their findings in other subsequent studies that have taken different courses. Dumouchel has clarified his concept of scarcity and has analyzed the relationship between envy and mimetic resentment through the study of Helmut Schoeck's famous envy theory.5 Meanwhile, Dupuy defends that many developments of modern economic science are merely the evolution of homo economicus to homo mimeticus because the autonomous subject is abandoned, giving rise to one that takes into account the behavior of others (game theory, adaptive expectations theory, speculation theory, etc.). Dupuy insists on the concept of the market as an institution that effectively delays the mimetic conflict. However, he adopts a pessimist position, as capitalism, due to its very evolution, has ended up surpassing its own limits (controlling politics), and as a result, it is increasingly more difficult for capitalism to carry out its function of containing violence.6Using the work of Dumouchel and Dupuy as a base, different authors have made contributions to economics from the perspective of MT. Several studies have been conducted on money, trade, and speculation, highlighting the theory of money of Michel Aglietta and André Orléan.7 Although there are differentiating nuances among the authors, they all assume that the money and market institutions are essentially violent and sacrificial. Other examples of this school of thought are Andrew Lascaris (1987), Erich Kitzmüller (1995), Anthony W. Bartlett (2002), John Daniels (2008), and Daniel M. Bell, Jr. (2012).8 Byrne Hobart and Tobias Huber have successfully applied MT to the study of financial bubbles in an economic history study, with promising results.9 And in the criticism of the market system in his book À Charge de Revanche, Mark R. Anspach [End Page 276] favors the need to overcome the perverse logic of revenge that defines both war and the market, transforming it into a positive reciprocity based on gifts.10 Except for Hobart and Huber, the cited authors overwhelmingly and explicitly reject... (shrink)

RESUMEN: Trata este trabajo de la actitud del presidente Barack Obama en relación con las rebeliones de la denominada Primavera Árabe, desvelando si los criterios de la guerra justa por él señalados y defendidos en sus discursos se compaginan con la real política bélica de Estados Unidos. Se insertan ambos planos en el escenario de las rebeliones acaecidas en tres países: Libia, Egipto y Túnez. La conclusión principal es que hay un largo, además de irregular, distanciamiento entre la teoría y (...) la práctica del presidente Obama, prevaleciendo los intereses de Estados Unidos por encima de la protección de los derechos humanos, que es uno de los vectores principales de su concepto de guerra justa.ABSTRACT: This work refers the attitude of the President Barack Obama concerning the rebellions of the so-called Arab Spring, revealing if the criteria of the just war defended in his speeches correspond to the real policy of the United States. Both planes are included in the scene of rebellions occurred in three countries: Libya, Egypt and Tunisia. The main conclusion is that there is a long, as well as irregular, distance between theory and practice of president Obama, prevailing the interests of United States respect to the protection of human rights, which is one of the main vectors of their concept of just war.PALABRAS CLAVE: primavera árabe, guerra justa, rebeliones árabes, Obama y política exterior, Obama y filosofía bélica.KEYWORDS: Arab spring, just war, Arab revolts, Obama and foreign policy, Obama and war philosophy. (shrink)

El manuscrito 2461 de la Biblioteca General de Rabat conserva un tercer zi)3 del astrónomo Muhammad ibn al-Raqqám al-Andalusí (m. 1315): al-Ziy al-Mustawfa. Los cánones (capitulo 18) y la tabla del movimiento del apogeo de al-Mustawfa están relacionados con el trabajo de Ibm Isháq al-Túnisí (1193-1222), quien compiló, probablemente, un conjunto de tablas carentes de cánones. Ibn al-Raqqám conocía bien el ziy de Ibn Isháq del que realizó dos recensiones conocidas hasta ahora: al-Ziy al- amil y al-Ziy al-Qawim. En al-Mustawfó, (...) tercera recensión de la misma obra, Ibn al-Raqqám aclara cuál era la opinión de Ibn Isl3áq sobre el movimiento de los apogeos planetarios y la división que existía, a este respecto, entre los astrónomos de la escuela andaluso-magrebí. (shrink)

La prisión, que hasta finales del siglo XVIII no pasó de ser una medida aseguradora de la presencia del reo en el proceso, fue experimentando a partir de entonces un rápido y progresivo avance como pena en los ordenamientos jurídicos no sólo por considerarse más humana y eficaz que las penas a las que fue sustituyendo -penas de muerte, corporales e infamantes-, sino sobre todo por su adaptabilidad a la gravedad del delito. Además, con la organización de la ejecución de (...) la pena de prisión de acuerdo con diferentes sistemas penitenciarios se va a pretender conseguir con ella algo más que la simple separación del condenado de la sociedad. Se va a intentar reintegrarlo a la sociedad para que en adelante sea capaz de vivir en paz con los demás. (shrink)

: We offer a response to three themes arising from the commentators’ inquiries and critiques: The epistemological compatibility of enactivism and conceptual metaphor theory; the ….

En este artículo se discute acerca de la existencia y la consistencia de un concepto de naturaleza humana en la obra de Nietzsche que no recaería en los extremos de las lecturas biologicistas ni historicistas de la misma. Para ello se lleva a cabo una interpretación que aúna la consideración nietzscheana de la naturaleza y de la historia alrededor del concepto-matriz de lo ahistórico, lo que conducirá la reflexión inicial sobre la cultura a un análisis en términos ontológico-formales de la (...) naturaleza del hombre y de su anclaje en la del mundo. (shrink)

The Convention on the Rights of Persons with Disabilities, approved on December 13, 2006 by the UN General Assembly, represented a historic advance in the field of disability by recognizing that the right to education implied the right to an quality inclusive education, thus consolidating a normative evolution from previous international instruments. Since May 3, 2008, the Convention has been part of the Spanish legal system, which implies that the State is obliged to modify national laws that do not correspond (...) to the principles established in the Convention. However, different reports have revealed the weakness of its implementation in Spain, with the consequent breach of the rights of people with disabilities. These difficulties in establishing a truly inclusive education show how ableist conceptions and practices continue to be perpetuated in the educational field. (shrink)