This book presents in brief, yet systematic way the philosophy of the great Indian thinker. The author's purpose in this book is "to present in English to the Western world the life and the philosophy of Gandhi and to show the importance of his ideals of truth, love, and non-violence for the solution of the social and political problems of the present age".

In the present article, the concept of Human Development Index has been revisited so as to integrate the human values using the Corruption Perception Index measured by Transparency International, for different countries, as a simple generalization within the framework of existing Anand and Sen’s and Haq’s prescription. In this framework, a geometrical average of three indices corresponding to three dimensions, namely, the life expectancy, years of schooling and standard of living, was taken. In order to have HDI in broader perspective, (...) one has to integrate another important dimension known as human values. The main hypotheses of this article are: human values play an important role in human development; CPI has a strong correlation with HDI; and CPI is intimately linked with the outcome of human values. The important finding of this article is the successful establishment of these hypotheses which brought appreciable changes in the HDI when human values are integrated with it. As a result, most of the countries showed a vast decline in HDI, affecting the respective ranking of different countries. Such a value-based HDI is supposed to motivate even the richer countries to improve their HDI ranking in future. (shrink)

Incomplete penetrance and variable expressivity are non‐Mendelian phenomena resulting in the lack of correlation between genotype and phenotype. Not withstanding the diversity in mechanisms, differential expression of homologous alleles within cells manifests as variations in penetrance and expressivity of mutations between individuals of the same genotype. These phenomena are seen most often in dominantly inherited diseases, implying that they are sensitive to concentration of the gene product. In this framework and the advances in understanding the role of microRNA (miRNA) in (...) fine‐tuning gene expression at translational level, we propose miRNA‐mediated regulation as a mechanism for incomplete penetrance and variable expressivity. The presence of miRNA binding sites at 3′ UTR, co‐expression of target gene–miRNA pairs for genes showing incomplete penetrance and variable expressivity derived from available data lend support to our hypothesis. Single nucleotide polymorphisms in the miRNA target site facilitate the implied differential targeting of the transcripts from homologous alleles. (shrink)