Results for 'Epileptic seizure detection'

985 found
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  1.  51
    Automated Epileptic Seizure Detection in Scalp EEG Based on Spatial-Temporal Complexity.Xinzhong Zhu, Huiying Xu, Jianmin Zhao & Jie Tian - 2017 - Complexity:1-8.
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  2.  25
    Detection Analysis of Epileptic EEG Using a Novel Random Forest Model Combined With Grid Search Optimization.Xiashuang Wang, Guanghong Gong, Ni Li & Shi Qiu - 2019 - Frontiers in Human Neuroscience 13:424082.
    In the automatic detection of epileptic seizures, the monitoring of critically ill patients with time varying EEG signals is an essential procedure in intensive care units. There is an increasing interest in using EEG analysis to detect seizure, and in this study we aim to get a better understanding of how to visualize the information in the EEG time-frequency feature, and design and train a novel random forest algorithm for EEG decoding, especially for multiple-levels of illness. Here, (...)
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  3. Neuronal dynamics and conscious experience: An example of reciprocal causation before epileptic seizures. [REVIEW]Michel Le Van Quyen & Claire Petitmengin - 2002 - Phenomenology and the Cognitive Sciences 1 (2):169-180.
    Neurophenomenology (Varela 1996) is not only philosophical but also empirical and experimental. Our purpose in this article is to illustrate concretely the efficiency of this approach in the field of neuroscience and, more precisely here, in epileptology. A number of recent observations have indicated that epileptic seizures do not arise suddenly simply as the effect of random fluctuations of brain activity, but require a process of pre-seizure changes that start long before. This has been reported at two different (...)
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  4.  36
    Why Won’t You Listen To Me? Predictive Neurotechnology and Epistemic Authority.Alessio Tacca & Frederic Gilbert - 2023 - Neuroethics 16 (3):1-12.
    From epileptic seizures to depressive symptoms, predictive neurotechnologies are used for a large range of applications. In this article we focus on advisory devices; namely, predictive neurotechnology programmed to detect specific neural events (e.g., epileptic seizure) and advise users to take necessary steps to reduce or avoid the impact of the forecasted neuroevent. Receiving advise from a predictive device is not without ethical concerns. The problem with predictive neural devices, in particular advisory ones, is the risk of (...)
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  5.  23
    First Epileptic Seizure and Initial Diagnosis of Juvenile Myoclonus Epilepsy (JME) in a Transcranial Direct Current Stimulation (tDCS) Study– Ethical Analysis of a Clinical case.Anna Sierawska, Vera Moliadze, Maike Splittgerber, Annette Rogge, Michael Siniatchkin & Alena Buyx - 2020 - Neuroethics 13 (3):347-351.
    We discuss an epileptic incident in an undiagnosed 13-year old girl participating in a clinical study investigating the effects of transcranial direct current stimulation in healthy children and adolescents. This incident poses important research ethics questions with regard to study design, especially pertaining to screening and gaining informed consent. Potential benefits and problems of the incident also need to be considered. The ethical analysis of the case presented in this paper has been informed by an in-depth interview conducted after (...)
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  6.  19
    Why Tononi is Wrong; Epileptic Seizure is More Complex Either than Sleep or the Resting State.Sean O. Nuallain & Doris - 2014 - Cosmos and History 10 (1):232-236.
    ECOG data obtained from a patient under conditions of resting brain, sleep and epileptic seizure were analyzed. Contrary to some theorists, the seizure state was found to be informationally the most complex of the three states. Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;}.
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  7.  27
    Global Epileptic Seizure Identification With Affinity Propagation Clustering Partition Mutual Information Using Cross-Layer Fully Connected Neural Network.Fengqin Wang & Hengjin Ke - 2018 - Frontiers in Human Neuroscience 12.
  8.  39
    The use of placebo as a provocative test in the diagnosis of psychogenic non epileptic seizures.Henda Foreid, Carla Bentes & José Pimentel - 2010 - Neuroethics 3 (2):95-98.
    Psychogenic non epileptic seizures (PNES) are clinical events of psychological nature. Video-electroencephalography monitoring (V-EEGM) is a valuable method for the diagnosis of PNES and may be combined with provocative tests to induce seizures. The use of placebo in provocative tests for the diagnosis of PNES is controversial because of associated deception, and contrasts with the use of truly decreasing epileptogenic threshold techniques such as hyperventilation and photo stimulation. We present a clinical case of a pregnant woman with a past (...)
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  9. Inducing an epileptic seizure for research–analysis.Alice Temple - 2012 - Research Ethics 8 (1):61-62.
  10. Inducing an Epileptic Seizure for Research.Georgia Testa - 2011 - Research Ethics 7 (4):158-158.
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  11.  33
    Level and contents of consciousness in connection with partial epileptic seizures.Mirja Johanson, Antii Revonsuo, John Chaplin & Jan-Eric Wedlund - 2003 - Epilepsy and Behavior 4 (3):279-285.
  12.  19
    Correction to: First Epileptic Seizure and Initial Diagnosis of Juvenile Myoclonus Epilepsy (JME) in a Transcranial Direct Current Stimulation (tDCS) Study– Ethical Analysis of a Clinical Case.Anna Sierawska, Vera Moliadze, Maike Splittgerber, Annette Rogge, Michael Siniatchkin & Alena Buyx - 2021 - Neuroethics 14 (3):575-576.
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  13. Newborn EEG seizure detection using signal structural complexity.L. Rankine, M. Mesbah & B. Boashash - 2004 - Complexity 500:15.
     
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  14.  10
    Activation of Functional Brain Networks in Children With Psychogenic Non-epileptic Seizures.Mohammadreza Radmanesh, Mahdi Jalili & Kasia Kozlowska - 2020 - Frontiers in Human Neuroscience 14.
  15.  48
    Neuropeptide FF receptors are implicated in epileptic seizures.Portelli Jeanelle, Meurs Alfred, Bihel Frederic, Hammoud Hassan, Schmitt Martine, De Kock Joery, Humbert Jean-Paul, Bertin Isabelle, Utard Valerie, Buffel Ine, Coppens Jessica, Tourwe Dirk, Maes Veronique, Vanhaecke Tamara, Massie Ann, Boon Paul, Michotte Yvette, Bourguignon Jean-Jacques, Simonin Frederic & Smolders Ilse - 2014 - Frontiers in Human Neuroscience 8.
  16.  37
    Properties of functional brain networks correlate with frequency of psychogenic non-epileptic seizures.Elham Barzegaran, Amir Joudaki, Mahdi Jalili, Andrea O. Rossetti, Richard S. Frackowiak & Maria G. Knyazeva - 2012 - Frontiers in Human Neuroscience 6.
  17.  43
    Seizure Prediction and Detection via Phase and Amplitude Lock Values.Mark H. Myers, Akshay Padmanabha, Gahangir Hossain, Amy L. de Jongh Curry & Charles D. Blaha - 2016 - Frontiers in Human Neuroscience 10.
  18.  68
    Anticipating seizure: Pre-reflective experience at the center of neuro-phenomenology.Claire Petitmengin, Vincent Navarro & Michel Le Van Quyen - 2007 - Consciousness and Cognition 16 (3):746-764.
    The purpose of this paper is to show through the concrete example of epileptic seizure anticipation how neuro-dynamic analysis and “pheno-dynamic” analysis may guide and determine each other. We will show that this dynamic approach to epileptic seizure makes it possible to consolidate the foundations of a cognitive non pharmacological therapy of epilepsy. We will also show through this example how the neuro-phenomenological co-determination could shed new light on the difficult problem of the “gap” which separates (...)
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  19.  27
    Anticipating seizure: Pre-reflective experience at the center of neuro-phenomenology.C. Petitmengin, V. NaVarro & M. Levanquyen - 2007 - Consciousness and Cognition 16 (3):746-764.
    The purpose of this paper is to show through the concrete example of epileptic seizure anticipation how neuro-dynamic analysis and “pheno-dynamic” analysis may guide and determine each other. We will show that this dynamic approach to epileptic seizure makes it possible to consolidate the foundations of a cognitive non pharmacological therapy of epilepsy. We will also show through this example how the neuro-phenomenological co-determination could shed new light on the difficult problem of the “gap” which separates (...)
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  20.  83
    Responsive Neurostimulation Targeting the Anterior, Centromedian and Pulvinar Thalamic Nuclei and the Detection of Electrographic Seizures in Pediatric and Young Adult Patients.Cameron P. Beaudreault, Carrie R. Muh, Alexandria Naftchi, Eris Spirollari, Ankita Das, Sima Vazquez, Vishad V. Sukul, Philip J. Overby, Michael E. Tobias, Patricia E. McGoldrick & Steven M. Wolf - 2022 - Frontiers in Human Neuroscience 16.
    BackgroundResponsive neurostimulation has been utilized as a treatment for intractable epilepsy. The RNS System delivers stimulation in response to detected abnormal activity, via leads covering the seizure foci, in response to detections of predefined epileptiform activity with the goal of decreasing seizure frequency and severity. While thalamic leads are often implanted in combination with cortical strip leads, implantation and stimulation with bilateral thalamic leads alone is less common, and the ability to detect electrographic seizures using RNS System thalamic (...)
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  21.  39
    Rhythmic Drumming in Contemporary Shamanism and Its Relationship to Auditory Driving and Risk of Seizure Precipitation in Epileptics.Peggy A. Wright - 1991 - Anthropology of Consciousness 2 (3-4):7-14.
  22.  86
    Epileptic High-Frequency Oscillations in Intracranial EEG Are Not Confounded by Cognitive Tasks.Ece Boran, Lennart Stieglitz & Johannes Sarnthein - 2021 - Frontiers in Human Neuroscience 15.
    Rationale: High-frequency oscillations in intracranial EEG are used to delineate the epileptogenic zone during presurgical diagnostic assessment in patients with epilepsy. HFOs are historically divided into ripples, fast ripples, and their co-occurrence. In a previous study, we had validated the rate of FRandRs during deep sleep to predict seizure outcome. Here, we ask whether epileptic FRandRs might be confounded by physiological FRandRs that are unrelated to epilepsy.Methods: We recorded iEEG in the medial temporal lobe MTL in 17 patients (...)
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  23.  18
    Psychosocial Stress, Epileptic-Like Symptoms and Psychotic Experiences.Petr Bob, Tereza Petraskova Touskova, Ondrej Pec, Jiri Raboch, Nash Boutros & Paul Lysaker - 2022 - Frontiers in Psychology 13.
    Current research suggests that stressful life experiences and situations create a substantive effect in the development of the initial manifestations of psychotic disorders and may influence temporo-limbic epileptic-like activity manifesting as cognitive and affective seizure-like symptoms in non-epileptic conditions. The current study assessed trauma history, hair cortisol levels, epileptic-like manifestations and other psychopathological symptoms in 56 drug naive adult young women experiencing their initial occurrence of psychosis. Hair cortisol levels among patients experiencing their initial episode of (...)
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  24.  35
    Implication of gamma band in Soman-induced seizures.G. Testylier, L. Tonduli & G. Lallement - 1999 - Acta Biotheoretica 47 (3-4):191-197.
    Soman, an anticholinesterasic neurotoxic drug, induces epileptic seizures during severe intoxication. Their trigger conditions still remain unknown and a great variability between animals is observed. The butterfly model in the catastrophe theory has been used to explain these triggering conditions.We have developed a technique allowing, in freely moving rats, the « in vivo » determination of three sets of neurophysiological data, followed before and during a soman intoxication. For the same rat, we associated cortical acetylcholinesterase (AChE) activity by microdialysis (...)
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  25. The Presence of Consciousness in Absence Seizures.Tim Bayne - 2011 - Behavioural Neurology 24 (1):47-53.
    Although the study of epileptic absence seizures has the potential to contribute a great deal to the scientific understanding of consciousness, this potential has yet to be fully exploited. There have been a number of insightful discussions of consciousness in the context of epileptic seizures, but the basic conceptual issues are still poorly understood and many empirical questions remain unexplored. In this paper I review a number of questions that are of interest to consciousness scientists and identify ways (...)
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  26.  23
    Time-dependent degree-degree correlations in epileptic brain networks: from assortative to dissortative mixing.Christian Geier, Klaus Lehnertz & Stephan Bialonski - 2015 - Frontiers in Human Neuroscience 9:150697.
    We investigate the long-term evolution of degree-degree correlations (assortativity) in functional brain networks from epilepsy patients. Functional networks are derived from continuous multi-day, multi-channel electroencephalographic data, which capture a wide range of physiological and pathophysiological activities. In contrast to previous studies which all reported functional brain networks to be assortative on average, even in case of various neurological and neurodegenerative disorders, we observe large fluctuations in time-resolved degree-degree correlations ranging from assortative to dissortative mixing. Moreover, in some patients these fluctuations (...)
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  27.  38
    Body-Mind Aporia in the Seizure of Othello.Thomas M. Vozar - 2012 - Philosophy and Literature 36 (1):183-186.
    One of the most curious events in Othello is the titular character’s epileptic fit, which does not appear in the story by Cinthio that is the accepted source of the play’s plot. Why does Shakespeare invent such an incident? The easiest direction to take is the equation of epilepsy with demonic possession, a common belief in the early modern period. In this essay, however, I argue from textual and critical evidence for a philosophical interpretation of Othello’s epilepsy: namely, that (...)
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  28.  80
    Viability of Preictal High-Frequency Oscillation Rates as a Biomarker for Seizure Prediction.Jared M. Scott, Stephen V. Gliske, Levin Kuhlmann & William C. Stacey - 2021 - Frontiers in Human Neuroscience 14.
    Motivation: There is an ongoing search for definitive and reliable biomarkers to forecast or predict imminent seizure onset, but to date most research has been limited to EEG with sampling rates <1,000 Hz. High-frequency oscillations have gained acceptance as an indicator of epileptic tissue, but few have investigated the temporal properties of HFOs or their potential role as a predictor in seizure prediction. Here we evaluate time-varying trends in preictal HFO rates as a potential biomarker of (...) prediction.Methods: HFOs were identified for all interictal and preictal periods with a validated automated detector in 27 patients who underwent intracranial EEG monitoring. We used LASSO logistic regression with several features of the HFO rate to distinguish preictal from interictal periods in each individual. We then tested these models with held-out data and evaluated their performance with the area-under-the-curve of their receiver-operating curve. Finally, we assessed the significance of these results using non-parametric statistical tests.Results: There was variability in the ability of HFOs to discern preictal from interictal states across our cohort. We identified a subset of 10 patients in whom the presence of the preictal state could be successfully predicted better than chance. For some of these individuals, average AUC in the held-out data reached higher than 0.80, which suggests that HFO rates can significantly differentiate preictal and interictal periods for certain patients.Significance: These findings show that temporal trends in HFO rate can predict the preictal state better than random chance in some individuals. Such promising results indicate that future prediction efforts would benefit from the inclusion of high-frequency information in their predictive models and technological architecture. (shrink)
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  29.  31
    Altered states of consciousness: experiences out of time and self.Marc Wittmann - 2018 - Cambridge, Massachusetts: MIT Press.
    What altered states of consciousness—the dissolution of feelings of time and self—can tell us about the mystery of consciousness. During extraordinary moments of consciousness—shock, meditative states and sudden mystical revelations, out-of-body experiences, or drug intoxication—our senses of time and self are altered; we may even feel time and self dissolving. These experiences have long been ignored by mainstream science, or considered crazy fantasies. Recent research, however, has located the neural underpinnings of these altered states of mind. In this book, neuropsychologist (...)
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  30.  53
    Damned if You Do, Damned if You Don't? The Lundbeck Case of Pentobarbital, the Guiding Principles on Business and Human Rights, and Competing Human Rights Responsibilities.Karin Buhmann - 2012 - Journal of Law, Medicine and Ethics 40 (2):206-219.
    In early 2011, news emerged that United States authorities had begun to apply injections of pentobarbital, a substance provided by Danish pharmaceutical company Lundbeck, when executing capital punishments. Lundbeck reported to be appalled by such unintended usage of pentobarbital, which is licensed for treatment of refractory forms of epilepsy and for usage as an anaesthetic.The human rights NGOs Reprieve and Amnesty International urged Lundbeck to ensure that pentobarbital was not made available to U.S. authorities for use in capital punishments. Lundbeck (...)
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  31.  47
    The “God Module” and the Complexifying Brain.Carol Rausch Albright, John R. Albright, Jensine Andresen, Robert W. Bertram, David M. Byers, Anna Case-Winters, Michael Cavanaugh, Philip Clayton, Gerald A. Cory Jr & Mihaly Csikszentmihalyi - 2000 - Zygon 35 (4):735-744.
    Recent reports of the discovery of a “God module” in the human brain derive from the fact that epileptic seizures in the left temporal lobe are associated with ecstatic feelings sometimes described as an experience of the presence of God. The brain area involved has been described as either (a) the seat of an innate human faculty for experiencing the divine or (b) the seat of religious delusions.In fact, religious experience is extremely various and involves many parts of the (...)
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  32.  25
    Emotional Prosody Processing in Epilepsy: Some Insights on Brain Reorganization.Lucy Alba-Ferrara, Silvia Kochen & Markus Hausmann - 2018 - Frontiers in Human Neuroscience 12:335228.
    Drug resistant epilepsy is one of the most complex, multifactorial and polygenic neurological syndrome. Besides its dynamicity and variability, it still provides us with a model to study brain-behavior relationship, giving cues on the anatomy and functional representation of brain function. Given that onset zone of focal epileptic seizures often affects different anatomical areas, cortical but limited to one hemisphere, this condition also let us study the functional differences of the left and right cerebral hemispheres. One lateralized function in (...)
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  33. What is an altered state of consciousness?Antti Revonsuo, Sakari Kallio & Pilleriin Sikka - 2009 - Philosophical Psychology 22 (2):187 – 204.
    “Altered State of Consciousness” (ASC) has been defined as a changed overall pattern of conscious experience, or as the subjective feeling and explicit recognition that one's own subjective experience has changed. We argue that these traditional definitions fail to draw a clear line between altered and normal states of consciousness (NSC). We outline a new definition of ASC and argue that the proper way to understand the concept of ASC is to regard it as a representational notion: the alteration that (...)
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  34.  66
    The "God Module" and the Complexifying Brain.Carol Rausch Albright - 2000 - Zygon 35 (4):735-744.
    Recent reports of the discovery of a “God module” in the human brain derive from the fact that epileptic seizures in the left temporal lobe are associated with ecstatic feelings sometimes described as an experience of the presence of God. The brain area involved has been described as either (a) the seat of an innate human faculty for experiencing the divine or (b) the seat of religious delusions.In fact, religious experience is extremely various and involves many parts of the (...)
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  35.  47
    Charlie Gard and the Limits of Parental Authority.Arthur Caplan & Kelly McBride Folkers - 2017 - Hastings Center Report 47 (5):15-16.
    The parents of Charlie Gard, who was born August 4, 2016, with an exceedingly rare and incurable disease called mitochondrial DNA depletion syndrome, fought a prolonged and heated legal battle to allow him access to experimental treatment that they hoped would prolong his life and to prevent his doctors from withdrawing life-sustaining care. Charlie's clinicians at the Great Ormond Street Hospital in London believed that the brain damage Charlie had suffered as a result of frequent epileptic seizures, along with (...)
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  36.  33
    Projective art and the ‘staging’ of empathic projection.Ken Wilder - unknown
    Michael Fried’s unexpected contribution to defining the ontological status of video art includes an intriguing claim that projective art is particularly suited to the ‘staging’ of empathic projection. Fried applies Stanley Cavell’s notion of empathic projection, developed in relation to skepticism of ‘other minds’, to moving image installations that not only exploit the beholder’s capacity for empathically projecting, but do so in such a way as to reveal the mechanism at play. In developing this claim, I compare Fried’s key example (...)
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  37.  19
    It Is Going to Be a Long Clinic Day.Salvador Cruz-Flores - 2023 - Narrative Inquiry in Bioethics 13 (1):29-30.
    In lieu of an abstract, here is a brief excerpt of the content:It Is Going to Be a Long Clinic DaySalvador Cruz-FloresIt was a routine neurology clinic day. I entered the room where one of the residents was seeing a patient that we will call Patty, a 32-year-old long-standing epilepsy patient. Patty was sitting in the chair with her husband by her side. She started screaming at me, complaining that she was tired of feeling sick and unable to do anything. (...)
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  38.  11
    Difficult, Difficult, Lemon, Difficult.Maggie Taylor - 2024 - Narrative Inquiry in Bioethics 14 (1):28-30.
    In lieu of an abstract, here is a brief excerpt of the content:Difficult, Difficult, Lemon, DifficultMaggie TaylorI like to joke that my husband is a lemon—he suffers from manufacturing defects that prevent his body from functioning as intended. Illnesses other 40-somethings recover from quickly are things that land him in the hospital for weeks on end. So, it was no surprise last year that an epileptic seizure led to aspiration pneumonia, admission to the lCU, intubation, multisystem organ failure, (...)
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  39.  32
    A Ca2+‐binding protein with numerous roles and uses: parvalbumin in molecular biology and physiology.Syed Hasan Arif - 2009 - Bioessays 31 (4):410-421.
    Parvalbumins (PVs) are acidic, intracellular Ca2+‐binding proteins of low molecular weight. They are associated with several Ca2+‐mediated cellular activities and physiological processes. It has been suggested that PV might function as a “Ca2+ shuttle” transporting Ca2+ from troponin‐C (TnC) to the sarcoplasmic reticulum (SR) Ca2+ pump during muscle relaxation. Thus, PV may contribute to the performance of rapid, phasic movements by accelerating the contraction–relaxation cycle of fast‐twitch muscle fibers. Interestingly, PVs promote the generation of power stroke in fish by speeding (...)
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  40.  18
    Turning a Drug Target into a Drug Candidate: A New Paradigm for Neurological Drug Discovery?Steven D. Buckingham, Harry-Jack Mann, Olivia K. Hearnden & David B. Sattelle - 2020 - Bioessays 42 (9):2000011.
    The conventional paradigm for developing new treatments for disease mainly involves either the discovery of new drug targets, or finding new, improved drugs for old targets. However, an ion channel found only in invertebrates offers the potential of a completely new paradigm in which an established drug target can be re‐engineered to serve as a new candidate therapeutic agent. The L‐glutamate‐gated chloride channels (GluCls) of invertebrates are absent from vertebrate genomes, offering the opportunity to introduce this exogenous, inhibitory, L‐glutamate receptor (...)
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  41.  13
    Children as voices and images for medicinal cannabis law reform. [REVIEW]Ian Freckelton Ao Qc - 2021 - Monash Bioethics Review 39 (1):4-25.
    This article situates the movement for the legalisation of medicinal cannabis within the bigger picture of the impetus toward recreational cannabis legalisation. It describes the role played by children with epileptic syndromes in the medicinal cannabis law reform campaigns in the United Kingdom, and Queensland, New South Wales and Victoria in Australia. Noting the ‘rule of rescue’ and the prominence in media campaigns of children in Australian and English cases of parental disputation with clinicians about treatment for their children, (...)
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  42. The burden of normality: from 'chronically ill' to 'symptom free'. New ethical challenges for deep brain stimulation postoperative treatment.Frederic Gilbert - 2012 - Journal of Medical Ethics 38 (7):408-412.
    Although an invasive medical intervention, Deep Brain Stimulation (DBS) has been regarded as an efficient and safe treatment of Parkinson’s disease for the last 20 years. In terms of clinical ethics, it is worth asking whether the use of DBS may have unanticipated negative effects similar to those associated with other types of psychosurgery. Clinical studies of epileptic patients who have undergone an anterior temporal lobectomy have identified a range of side effects and complications in a number of domains: (...)
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  43.  53
    'Typical dreams' reflections of arousal.Rainer Schonhammer - 2005 - Journal of Consciousness Studies 12 (4-5):18-37.
    Dreams of chase or pursuit, falling, sex, flying, nudity, failing an examination, one's own and other's death, fire, teeth falling out and some other themes experienced, even if only rarely, by many people all over the world have been labelled 'typical dreams'. This essay argues that typical dreaming, rather a syndrome of themes than monothematic, reflects an extraordinary state of mind and brain. Odd and particularly memorable perceptions, as well as emerging awareness of sleep and dreaming -- i.e. parallels to (...)
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  44.  34
    Intracranial EEG power spectra and phase synchrony during consciousness and unconsciousness.Susan Pockett & Mark D. Holmes - 2009 - Consciousness and Cognition 18 (4):1049-1055.
    Power density spectra and phase synchrony measurements were taken from intracranial electrode grids implanted in epileptic subjects. Comparisons were made between data from the waking state and from the period of unconsciousness immediately following a generalised tonic–clonic seizure. Power spectra in the waking state resembled coloured noise. Power spectra in the unconscious state resembled coloured noise from 1 to about 5 Hz, but at higher frequencies changed in two out of three subjects to resemble white noise. This boosted (...)
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  45.  28
    Antiepileptic Efficacy and Network Connectivity Modulation of Repetitive Transcranial Magnetic Stimulation by Vertex Suppression.Cong Fu, Aikedan Aisikaer, Zhijuan Chen, Qing Yu, Jianzhong Yin & Weidong Yang - 2021 - Frontiers in Human Neuroscience 15.
    A core feature of drug-resistant epilepsy is hyperexcitability in the motor cortex, and low-frequency repetitive transcranial magnetic stimulation is a suitable treatment for seizures. However, the antiepileptic effect causing network reorganization has rarely been studied. Here, we assessed the impact of rTMS on functional network connectivity in resting functional networks and their relation to treatment response. Fourteen patients with medically intractable epilepsy received inhibitive rTMS with a figure-of-eight coil over the vertex for 10 days spread across two weeks. We designed (...)
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  46.  18
    Longitudinal neurological analysis of moderate and severe pediatric cerebral visual impairment.Andres Jimenez-Gomez, Kristen S. Fisher, Kevin X. Zhang, Chunyan Liu, Qin Sun & Veeral S. Shah - 2022 - Frontiers in Human Neuroscience 16.
    IntroductionCerebral visual impairment results from damage to cerebral visual processing structures. It is the most common cause of pediatric visual impairment in developed countries and rising in prevalence in developing nations. There is currently limited understanding on how neurologic, developmental, and ophthalmic factors predict outcome for pediatric CVI.MethodA retrospective manual chart review of pediatric CVI patients seen at the tertiary pediatric hospital neurology and neuro-ophthalmology service between 2010 and 2019 was conducted. Patients were stratified into severity groups, and followed over (...)
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  47.  21
    Centromedian Nucleus of the Thalamus Deep Brain Stimulation for Genetic Generalized Epilepsy: A Case Report and Review of Literature.Shruti Agashe, David Burkholder, Keith Starnes, Jamie J. Van Gompel, Brian N. Lundstrom, Gregory A. Worrell & Nicholas M. Gregg - 2022 - Frontiers in Human Neuroscience 16.
    There is a paucity of treatment options for cognitively normal individuals with drug resistant genetic generalized epilepsy. Centromedian nucleus of the thalamus deep brain stimulation may be a viable treatment for GGE. Here, we present the case of a 27-year-old cognitively normal woman with drug resistant GGE, with childhood onset. Seizure semiology are absence seizures and generalized onset tonic clonic seizures. At baseline she had 4–8 GTC seizures per month and weekly absence seizures despite three antiseizure medications and vagus (...)
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    Multi-modal Mapping of the Face Selective Ventral Temporal Cortex–A Group Study With Clinical Implications for ECS, ECoG, and fMRI.Takahiro Sanada, Christoph Kapeller, Michael Jordan, Johannes Grünwald, Takumi Mitsuhashi, Hiroshi Ogawa, Ryogo Anei & Christoph Guger - 2021 - Frontiers in Human Neuroscience 15.
    Face recognition is impaired in patients with prosopagnosia, which may occur as a side effect of neurosurgical procedures. Face selective regions on the ventral temporal cortex have been localized with electrical cortical stimulation, electrocorticography, and functional magnetic resonance imagining. This is the first group study using within-patient comparisons to validate face selective regions mapping, utilizing the aforementioned modalities. Five patients underwent surgical treatment of intractable epilepsy and joined the study. Subdural grid electrodes were implanted on their ventral temporal cortices to (...)
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  49. Beware of frontal lobe deficits in hippocampal clothing.Suzanne Corkin - 2001 - Trends in Cognitive Sciences 5 (8):321-323.
    The Wisconsin card-sorting test (WCST) is a commonly used clinical tool for the detection of frontal lobe dysfunction, specifically executive dysfunction. Patients with lesions outside the frontal lobes sometimes show deficits on the WCST, however, and some researchers have implicated hippocampal dysfunction as the cause of the deficit. But a critical role for the hippocampus seems to be untenable because amnesic patients with bilateral medial temporal lobe (MTL) lesions perform the WCST normally. In the case of epileptic patients, (...)
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    The Epistemological Consequences of Artificial Intelligence, Precision Medicine, and Implantable Brain-Computer Interfaces.Ian Stevens - 2024 - Voices in Bioethics 10.
    ABSTRACT I argue that this examination and appreciation for the shift to abductive reasoning should be extended to the intersection of neuroscience and novel brain-computer interfaces too. This paper highlights the implications of applying abductive reasoning to personalized implantable neurotechnologies. Then, it explores whether abductive reasoning is sufficient to justify insurance coverage for devices absent widespread clinical trials, which are better applied to one-size-fits-all treatments. INTRODUCTION In contrast to the classic model of randomized-control trials, often with a large number of (...)
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