The paper proposes a parallel reading of Albrecht Dürer’s engraving ›Melencolia I‹ (1514) and Alfred Sohn-Rethel’s notion of real abstraction. It argues for a constitutive link between the abstractions operative in ›Melencolia I‹, in commodity exchange, and in certain formations of psychological suffering, most notably described in the psychoanalytic conception of melancholia theorized by Sigmund Freud and the subsequent Lacanian tradition. With and against the iconographic analysis put forward by Raymond Klibansky, Erwin Panofsky, and Fritz Saxl in ›Saturn and Melancholy‹ (...) (1964), this paper understands the engraving’s polyhedron as a pivot point in Dürer’s artwork and in art history in general – namely, as a stumbling block that indicates the negativity of abstraction through its very positive existence. Abstraction, understood in this specific sense, and contrary to classical ontology and epistemology can in fact constitute a world of real material social relations instantiated through acts (and failures) of exchange. (shrink)