Alternative splicing is a well‐characterized mechanism by which multiple transcripts are generated from a single mRNA precursor. By allowing production of several protein isoforms from one pre‐mRNA, alternative splicing contributes to proteomic diversity. But what do we know about the origin of this mechanism? Do the same evolutionary forces apply to alternatively and constitutively splice exons? Do similar forces act on all types of alternative splicing? Are the products generated by alternative splicing functional? Why is “improper” recognition of exons and (...) introns allowed by the splicing machinery? In this review, we summarize the current knowledge regarding these issues from an evolutionary perspective. BioEssays 30:38–47, 2008. © 2007 Wiley Periodicals, Inc. (shrink)

The German philosopher and philologist Friedrich Ast published this monumental lexicon in three volumes. A professor of classical literature at the University of Landshut and member of the Bavarian Academy of Sciences, Ast wrote widely on the history of philosophy. He edited a complete edition of Plato with Latin translation, identifying spurious interpolations and false attributions, using this as a basis for his Lexicon. The entries give citations both from Plato and from later works that extensively quote Plato. Though the (...) Lexicon met with criticism for omissions of particles, prepositions and proper names, and the lack of systematic arrangement, it had a high reputation throughout the nineteenth century. It remains a milestone in Plato scholarship and is an indispensable resource for readers interested in the history of philology and methods in textual criticism. (shrink)

The recent in vitro derivation of gamete‐like cells from mouse embryonic stem (mES) cells is a major breakthrough and lays down several challenges, both for the further scientific investigation and for the bioethical and biolegal discourse. We refer here to these cells as gamete‐like (sperm‐like or oocyte‐like, respectively), because at present there is still no evidence that these cells behave fully like bona fide sperm or oocytes, lacking the fundamental proof, i.e. combination with a normally derived gamete of the opposite (...) sex to yield a normal individual. However, the results published so far do show that these cells share some defining features of gametes. We discuss these results in the light of the bioethical and legal questions that are likely to arise would the same process become possible with human embryonic stem (hES) cells. (shrink)

Downward causation exercised by emergent properties of wholes upon their lower-level constituents’ properties has been accused of conceptual and metaphysical incoherence. Only upward causation is usually peacefully accepted. The aim of this paper is to criticize and refuse the traditional hierarchical-vertical way of conceiving both types of causation, although preserving their deepest ontological significance, as well as the widespread acceptance of the traditional atomistic-combinatorial view of the entities and the relations that constitute the so-called ‘emergence base’. Assuming those two perspectives (...) with no reserves, we are condemned to confine our debate to the question of whether reified wholes can have the power to downwardly change or influence their lower-level parts, a question which seems profoundly misleading to me. I therefore propose an alternative relational ontological view, assuming a straightforward horizontal and intra-level way of representing those putative cases of cross-level causation. I finally confront two recent replies to Kim’s well-known objections to DC—Craver and Bechtel and Kistler :595–609, 2009)—, emphasizing their global positive approaches, as well as the reasons why their accounts still seem insufficient to me. I conclude arguing that both Kim’s principle of the causal closure of the physical domain and its allegation of an overdetermination in cases of DC can be surpassed by the new relational ontological perspective presented here. (shrink)

El presente artículo tiene por objeto analizar los límites y exigencias de la mirada en la poética de Alberto Caeiro, heterónimo de Fernando Pessoa. Esta mirada, sostiene Gil, es singular, supone un proceso de crítica de la tradicional relación sujeto - objeto en el acto de conocer. Una especie de epojé en el sentido fenomenológico. No es una mirada empírica, no apela a los sentidos, es una mirada que tiene más bien el carácter de “una intuición intelectual de los sentidos”. (...) El propósito de fondo del artículo es mostrar cómo el paganismo preconizado por Caeiro apela a un “objetivismo absoluto” y reivindica como su invención más propia una armonización del acto de sentir con el de pensar. El ensayo de Gil desarrolla sus argumentos siguiendo minuciosamente algunos de los poemas del poeta caeiro así como algunas de las afirmaciones dedicadas a él por el propio Pessoa. (shrink)

The German philosopher and philologist Friedrich Ast published this monumental lexicon in three volumes. A professor of classical literature at the University of Landshut and member of the Bavarian Academy of Sciences, Ast wrote widely on the history of philosophy. He edited a complete edition of Plato with Latin translation, identifying spurious interpolations and false attributions, using this as a basis for his Lexicon. The work is arranged alphabetically, Volume 1 covering Alpha to Epsilon. The entries give citations both from (...) Plato and from later works that extensively quote Plato. Though the Lexicon met with criticism for omissions of particles, prepositions and proper names, and the lack of systematic arrangement, it had a high reputation throughout the nineteenth century. It remains a milestone of Plato scholarship and is an indispensable resource for readers interested in the history of philology and methods in textual criticism. (shrink)

_Blood_, according to Gil Anidjar, maps the singular history of Christianity. As a category for historical analysis, blood can be seen through its literal and metaphorical uses as determining, sometimes even defining Western culture, politics, and social practices and their wide-ranging incarnations in nationalism, capitalism, and law. Engaging with a variety of sources, Anidjar explores the presence and the absence, the making and unmaking of blood in philosophy and medicine, law and literature, and economic and political thought from ancient Greece (...) to medieval Spain, from the Bible to Shakespeare and Melville. The prevalence of blood in the social, juridical, and political organization of the modern West signals that we do not live in a secular age into which religion could return. Flowing across multiple boundaries, infusing them with violent precepts that we must address, blood undoes the presumed oppositions between religion and politics, economy and theology, and kinship and race. It demonstrates that what we think of as modern is in fact imbued with Christianity. Christianity, Blood fiercely argues, must be reconsidered beyond the boundaries of religion alone. (shrink)

The medical profession is observing a rising number of calls to action considering the threat that climate change poses to global human health. Theory-led bioethical analyses of the scope and weight of physicians’ normative duty towards climate protection and its conflict with individual patient care are currently scarce. This article offers an analysis of the normative issues at stake by using Korsgaard’s neo-Kantian moral account of practical identities. We begin by showing the case of physicians’ duty to climate protection, before (...) we succinctly introduce Korsgaard’s account. We subsequently show how the duty to climate protection can follow from physicians’ identity of being a healthcare professional. We structure conflicts between individual patient care and climate protection, and show how a transformation in physicians’ professional ethos is possible and what mechanisms could be used for doing so. An important limit of our analysis is that we mainly address the level of individual physicians and their practical identities, leaving out important measures to respond to climate change at the mesolevels and macrolevels of healthcare institutions and systems, respectively. (shrink)

The German philosopher and philologist Friedrich Ast published this monumental lexicon in three volumes. A professor of classical literature at the University of Landshut and member of the Bavarian Academy of Sciences, Ast wrote widely on the history of philosophy. He edited a complete edition of Plato with Latin translation, identifying spurious interpolations and false attributions, using this as a basis for his Lexicon. The work is arranged alphabetically, Volume 2 covering Theta to Omicron. The entries give citations both from (...) Plato and from later works that extensively quote Plato. Though the Lexicon met with criticism for omissions of particles, prepositions and proper names, and the lack of systematic arrangement, it had a high reputation throughout the nineteenth century. It remains a milestone in Plato scholarship and is an indispensable resource for readers interested in the history of philology and methods in textual criticism. (shrink)

The German philosopher and philologist Friedrich Ast published this monumental lexicon in three volumes. A professor of classical literature at the University of Landshut and member of the Bavarian Academy of Sciences, Ast wrote widely on the history of philosophy. He edited a complete edition of Plato with Latin translation, identifying spurious interpolations and false attributions, using this as a basis for his Lexicon. The work is arranged alphabetically, Volume 3 covering Pi to Omega. The entries give citations both from (...) Plato and from later works that extensively quote Plato. Though the Lexicon met with criticism for omissions of particles, prepositions and proper names, and the lack of systematic arrangement, it had a high reputation throughout the nineteenth century. It remains a milestone in Plato scholarship and is an indispensable resource for readers interested in the history of philology and methods in textual criticism. (shrink)

This article explores the theological role of cities in Judaism as settings for the mediation between the heavenly and earthly realms. By way of juxtaposing the late antique city of Sepphoris and the modern settlement of Me'ah She'arim in Jerusalem, two understandings of this mediation will be studied dialectically. The differences and similarities between the two communities and their self-representation through urban architecture reveal the ways in which the highest religious symbols are manifested in the life of a city. They (...) also unfold the transformation of modernity and the particular interpretation of a Jewish settlement it inspired. (shrink)

Physicians frequently encounter situations in which their professional practice is intermingled with moral affordances stemming from other domains of the physician’s lifeworld, such as family and friends, or from general morality pertaining to all humans. This article offers a typology of moral conflicts ‘at the margins of professionalism’ as well as a new theoretical framework for dealing with them. We start out by arguing that established theories of professional ethics do not offer sufficient guidance in situations where professional ethics overlaps (...) with moral duties of other origins. Therefore, we introduce the moral theory developed by Christine M. Korsgaard, that centres around the concept of practical identity. We show how Korsgaard’s account offers a framework for interpreting different types of moral conflicts ‘at the margins of professionalism’ to provide either orientation for solving the conflict or an explanation for the emotional and moral burden involved in moral dilemmas. (shrink)

Gil R, Arroyo-Anllo EM, Ingrand P, Gil M, Neau JP, Ornon C, Bonnaud V. Self-consciousness and Alzheimer’s disease. Acta Neurol Scand 2001: 104: 296–300. # Munksgaard 2001. Objectives – To propose a neuropsychological study of the various aspects of self-consciousness (SC) in Alzheimer’s disease. Methods – Forty-five patients with probable mild or moderate AD were included in the study. Severity of their dementia was assessed by the Mini Mental State (MMS). Fourteen questions were prepared to evaluate SC. Results – No (...) significant correlations were found between SC score and educational level, age, and duration of disease. A significant correlation was found between SC score and the severity of dementia, whereas frontal disturbances were just short of the significance threshold. The various aspects of SC were not impaired to the same degree. The most disturbed ones were awareness of cognitive deficiencies, moral judgements and prospective memory. The least disturbed aspects were awareness of identity and of mental representation of the body. Items relating to anosognosia and moral judgements were significantly correlated with the MMS score, whereas affective state, body representation disorders, prospective memory, and capacities for introspection were not related to the severity of the dementia. Consciousness of identity was sound, regardless of MMS score. Conclusions – AD clearly induces an heterogeneous impairment of SC. SC requires a convergence of many neural networks. In AD, neuronal alterations involve many cortical areas and information sent to the associative frontal cortex from memory, language and visuospatial areas is lacking or disturbed. Thus, the sequential order of successive stimuli cannot be maintained by the heteromodal associative cortex (dorsal convexity of the prefrontal cortex), and the supramodal associative cortex (located rostrally in the frontal lobes) is unable to provide reliable monitoring and assessment of simultaneous neural cognitive networks carrying insufficient and inadequate input. The core deficiency in AD patients might be impaired SC equated with the disability to maintain sequential and simultaneous ‘‘attention to life’’. The Self-Consciousness Questionnaire, a clinical scale providing multidimensional measurement, indicates that different aspects of consciousness are not correlated with overall cognitive deficiency as determined by the MMSE. (shrink)

Integrative Social Contracts Theory is a popular framework to assist managers in making decisions on international moral dilemmas. Although the theory has been praised for its comprehensiveness and sophistication, commentators have raised concerns regarding the justification and identification of substantive hypernorms, fundamental moral principles valid across cultures. This paper introduces the deliberative test, a new method for testing the cross-cultural validity of ethical norms in ISCT. The test relies on the concept of Deliberative Capacity, arising from new developments in system-level (...) deliberative democracy research, which studies deliberation at the level of national societies and over time. Based on this recent stream of research, the deliberative test has the potential of providing better guidance for managers to decide which norms to follow in case of conflicting standards between home and host countries. (shrink)

Thomas Gil und Wolfgang Mack befassen sich aus der Perspektive zweier unterschiedlicher Disziplinen –Philosophie und Psychologie – mit der Frage nach den Funktionen der Seele. Aus der Sicht der Philosophie wird untersucht, was unter psychischen Funktionen zu verstehen ist. Aus der Sicht der Psychologie wird der Begriff der Seele historisch-kritisch diskutiert. Ist für die Psychologie die Seele als wissenschaftlicher Begriff möglicherweise (wieder) geeignet? In gemeinsamer Diskussion beantworten die Autoren die Frage danach, was das Psychische ist.

To advance current knowledge on ethical decision-making in organizations, we integrate two perspectives that have thus far developed independently: the organizational identification perspective and the ethical climate perspective. We illustrate the interaction between these perspectives in two studies, in which we presented participants with moral business dilemmas. Specifically, we found that organizational identification increased moral decision-making only when the organization’s climate was perceived to be ethical. In addition, we disentangle this effect in Study 2 from participants’ moral identity. We argue (...) that the interactive influence of organizational identification and ethical climate, rather than the independent influence of either of these perspectives, is crucial for understanding moral decision-making in organizations. (shrink)

This essay offers a conception of logic by which logic may be considered to be exceptional among the sciences on the backdrop of a naturalistic outlook. The conception of logic focused on emphasises the traditional role of logic as a methodology for the sciences, which distinguishes it from other sciences that are not methodological. On the proposed conception, the methodological aims of logic drive its definitions and principles, rather than the description of scientific phenomena. The notion of a methodological discipline (...) is explained as a relation between disciplines or practices. Logic serves as a methodological discipline with respect to any theoretical practice, and this generality, as well as logic’s reflexive nature, distinguish it from other methodological disciplines. Finally, the evolution of model theory is taken as a case study, with a focus on its methodological role. Following recent work by John Baldwin and Juliette Kennedy, we look at model theory from its inception in the mid-twentieth century as a foundational endeavour until developments at the end of the century, where the classification of theories has taken centre-stage. (shrink)

In standard model-theoretic semantics, the meaning of logical terms is said to be fixed in the system while that of nonlogical terms remains variable. Much effort has been devoted to characterizing logical terms, those terms that should be fixed, but little has been said on their role in logical systems: on what fixing their meaning precisely amounts to. My proposal is that when a term is considered logical in model theory, what gets fixed is its intension rather than its extension. (...) I provide a rigorous way of spelling out this idea, and show that it leads to a graded account of logicality: the less structure a term requires in order for its intension to be fixed, the more logical it is. Finally, I focus on the class of terms that are invariant under isomorphisms, as they render themselves more easily to mathematical treatment. I propose a mathematical measure for the logicality of such terms based on their associated Löwenheim numbers. (shrink)

Organ transplantation remains one of modern medicine's remarkable achievements. It saves lives, improves quality of life, diminishes healthcare expenditures in end-stage renal patients, and enjoys high success rates. Yet the promise of transplantation is substantially compromised by the scarcity of organs. The gap between the number of patients on waiting lists and the number of available organs continues to grow. As of January 2006, the combined waiting list for all organs in the United States was 90,284. Unfortunately, thousands of potential (...) organs are lost each year, primarily due to lack of consent to donation from the deceased before death, or from the family thereafter. Only fifty percent of potential donors – the “conversion” rate – become actual donors. The costs attributed to organ shortage are substantial – Medicare paid over $15.5 billion in 2002 for treating patients with end-stage renal-disease, who predominate on organ waiting lists. (shrink)

La microfísica del poder –de la qual Michel Foucault esdevé el principal exponent– emergeix com un efecte del panorama que segueix el Maig del 68, en el qual sorgeix un cicle de noves lluites centrades en el reconeixement i el desenvolupament de nous tipus de subjectivitat. Ara que han passat trenta anys des de la mort de l’autor, defensaré la necessitat d’aplicar la microfísica del poder a una realitat que ja no pot respondre a unes anàlisis fonamentades en paràmetres estrictament (...) econòmics i que demanda, en canvi, eixamplar el camp de visió per incloure-hi el paper que juga el poder en la producció de les subjectivitats. (shrink)

El debate sobre la justicia distributiva internacional se ha centrado tradicionalmente en una discusión normativa acerca del alcance de las obligaciones de los ciudadanos de los pueblos ricos hacia los pobres del extranjero. Las distintas posiciones presuponen ciertas nociones económicas empíricas a la hora de emitir juicios sobre la justicia del ordenamiento económico internacional. En función de las teorías económicas que se tengan por válidas, una misma posición normativa puede justificar distintos ordenamientos incompatibles de las instituciones económicas internacionales. Este artículo (...) busca explicitar las nociones empíricas que subyacen en las posiciones normativas y propone un consenso económico superpuesto para alcanzar una base de justificación neutral que permita fundamentar juicios sobre la justicia del ordenamiento económico internacional. The international distributive justice debate has traditionally focused on a normative discussion about the scope of the obligations of the citizens of the rich countries to the global poor. The various positions assume certain empirical economic notions when making judgments about the justice of the international economic order. Depending on the economic theory held as valid, the same normative position may justify diametrically opposed configurations of the international economic institutions. This article seeks to make explicit the empirical notions underlying normative positions, and proposes an overlapping economic consensus to reach a basis for the neutral justification of claims about the justice of the international economic order. (shrink)

Neste estudo procuramos avaliar a dimensão humana presente na Palavra de Deus. O autor sagrado está dentro de um contexto de vida cultural, e recebe os condicionamentos do seu tempo. A Bíblia deve ser lida com o espírito que foi escrita e não simplesmente vista como uma palavra literal de Deus para os homens.

Feelings are conscious mental events that represent body states as they undergo homeostatic regulation. Feelings depend on the interoceptive nervous system (INS), a collection of peripheral and central pathways, nuclei and cortical regions which continuously sense chemical and anatomical changes in the organism. How such humoral and neural signals come to generate conscious mental states has been a major scientific question. The answer proposed here invokes (1) several distinctive and poorly known physiological features of the INS; and (2) a unique (...) interaction between the body (the ‘object’ of interoception) and the central nervous system (which generates the 'subject' of interoception). The atypical traits of the INS and the direct interactions between neural and non‐neural physiological compartments of the organism, neither of which is present in exteroceptive systems, plausibly explain the qualitative and subjective aspects of feelings, thus accounting for their conscious nature. (shrink)

Acts of Religion, compiled in close association with Jacques Derrida, brings together for the first time a number of Derrida's writings on religion and questions of faith and their relation to philosophy and political culture. The essays discuss religious texts from Jewish, Christian, and Muslim traditions, as well as religious thinkers such as Kant, Levinas, and Gershom Scholem, and comprise pieces spanning Derrida's career. The collection includes two new essays by Derrida that appear here for the first time in any (...) language, as well as a substantial introduction by Gil Anidjar that explores Derrida's return to his own "religious" origins and his attempts to bring to light hidden religious dimensions of the social, cultural, historical, and political. (shrink)

Policy-makers sometimes aim to improve well-being as a policy goal, but to do this they need some way to measure well-being. Instead of relying on potentially problematic theories of well-being to justify their choice of well-being measure, Daniel Hausman proposes that policy-makers can sometimes rely on preference-based measures as evidence for well-being. I claim that Hausman’s evidential account does not justify the use of any one measure more than it justifies the use of any other measure. This leaves us at (...) a loss as to which policy should be chosen in the non-trivial cases for which there is substantial disagreement between the different measures in their assessment of policy. (shrink)

Background and Objectives People living with dementia have historically been excluded from qualitative research and their voices ignored due to the perception that a person with dementia is not able to express their opinions, preferences and feelings. Research institutions and organizations have contributed by adopting a paternalistic posture of overprotection. Furthermore, traditional research methods have proven to be exclusionary towards this group. The objective of this paper is to address the issue of inclusion of people with dementia in research and (...) provide an evidence-based framework for dementia researchers based on the five principles of human rights: Participation, Accountability, Non-discrimination and equality, Empowerment and Legality (PANEL). Design This paper adapts the PANEL principles to the research context, and uses evidence from the literature to create a framework for qualitative research in people with dementia. This new framework aims to guide dementia researchers in designing studies around the needs of people with dementia, to improve involvement and participation, facilitate research development and maximize research outcomes. Results A checklist is presented with questions related to the five PANEL principles. These questions cover ethical, methodological and legal issues that researchers may need to consider while developing qualitative research for people with dementia. Conclusions The proposed checklist offers a series of questions and considerations to facilitate the development of qualitative research in patients with dementia. It is inspired by current human rights work of recognized dementia researchers and organizations who have been directly involved in policy development. Future studies need to explore its utility in improving participation, facilitating ethics approvals and ensuring that outcomes are relevant to people with dementia. (shrink)

In this paper I present an interpretation of Deleuze's concept of the virtual. I argue that this concept is best understood in relation to the problematic of individuation or differentiation, which Deleuze inherits from Duns Scotus. After analysing Scotus' critique of Aristotelian or hylomorphic approaches to the problem of individuation, I turn to Deleuze's account of differentiation and his interpretation of the calculus in chapter 4 of Difference and Repetition. The paper seeks thereby to explicate Deleuze's dialectics or theory of (...) Ideas, his approach to the principle of sufficient reason, and the concept of the virtual itself. (shrink)

Contextualist theories of truth appeal to context to solve the liar paradox: different stages of reasoning occur in different contexts, and so the contradiction is dispelled. The word ‘true’ is relativized by the contextualists to contexts of use. This paper shows that contextualist approaches to the liar are committed to a form of semantic relativism: that the truth value of some sentences depends on the context of assessment, as well as the context of use. In particular, it is shown how (...) Simmons’s and Glanzberg’s contextualist approaches entail relativism. In both cases, the liar sentence gets different semantic evaluations as uttered in a fixed context of use but assessed from different contexts. Shift in context of use alone cannot provide the full explanation of the liar. These contextualist approaches, as originally presented, were thus mischaracterised and they should be re-evaluated according to their full implications. (shrink)

Physicians frequently encounter situations in which their professional practice is intermingled with moral affordances stemming from other domains of the physician’s lifeworld, such as family and friends, or from general morality pertaining to all humans. This article offers a typology of moral conflicts ‘at the margins of professionalism’ as well as a new theoretical framework for dealing with them. We start out by arguing that established theories of professional ethics do not offer sufficient guidance in situations where professional ethics overlaps (...) with moral duties of other origins. Therefore, we introduce the moral theory developed by Christine M. Korsgaard, that centres around the concept of practical identity. We show how Korsgaard’s account offers a framework for interpreting different types of moral conflicts ‘at the margins of professionalism’ to provide either orientation for solving the conflict or an explanation for the emotional and moral burden involved in moral dilemmas. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:THE VINE AND BRANCHES DISCOURSE: THE GOSPEL'S PSYCHOLOGICAL APOCALYPSE Gil Bailie Florilegio Institute Man is after something that cannot be possessed.... Man cannot "have" being, though he absolutely needs it for living. (Roel Kaptein) The anthropological reading of biblical literature which Girard's mimetic theory makes possible sheds new light on many otherwise inscrutable texts. Prominent among these, due to its centrality as well as its elusiveness, is the prologue (...) to the Gospel ofJohn. For the author of this gospel, the "Word" who was "in the beginning," was "the light" without which humanity remained in darkness—whether it be the darkness ofpre-human existence or the moral and mythic darkness of the sacred violence that accompanied hominization. Girard's work helps us realize that humanity generated its own crude forms of illumination precisely by periodically expelling this light. (A vivid symbolic expression ofthis is the reference to the "lanterns, torches, and weapons" with which the Roman cohort arrested Jesus later in John's Gospel.) The Johannine Prologue conveys its message in an elusively universal yet specifiable idiom: The true light, which enlightens everyone, was coming into the world. He was in the world, and the world came into being through him; yet the world did not know him. He came to what Gil Bailie121 was his own, and his own people did not accept him. But to all who did accept him, who believed in his name, he gave the power to become children of God, who were born, not of blood or ofthe will of the flesh or of the will of man, but of God. (1 : 9-13) The ontological theme of these verses deserves attention. If, as Raymond Brown has observed, these verses constitute a "description of the history of salvation in hymnic form," they also contain an anthropological summary of the two, and only two, ontologizing circumstances: the identification, respectively, with the victimizing crowd and with the victim. However occluded the illuminating Logos might have been prior to revelation ofthe Cross, the Johannine prologue tells us that it was present from the beginning. How? The most pertinent scriptural clue seems to be the reference to Christ in the Book of Revelation as "the Lamb slain from the foundation of the world," the innocent One whose victimization finally broke open the seals on the scroll of human iniquity and, in the process, unfettered that iniquity from its ancient restraints. One of the great values of Girard's work is that it makes anthropologically explicit what is poetically implicit in these scriptural innuendoes, namely, the link between the Crucified One and all victims slain "from the foundation of the world." Inasmuch as "the Lamb slain from the foundation of the world" was what made the old humanity possible and, in Christ, what brought the new humanity into being, the third verse of the prologue of John's Gospel becomes anthropologically intelligible: All things came into being through him, not one thing had its being except through him. (1:3) Here the explicit claim that all things came to be through him needs to be read in light of the verses that follow in the prologue, but which I have quoted above. Doing so, we are led to consider the radical difference between the crude and fallacious ontology the ancient sacrificial system was able to underwrite by causing its beneficiaries to identify with the victimizing crowd and the ontological renewal born of an identification with the innocent victim—referred to in the New Testament as a dying with Christ and ritualized in baptism. With equal subtlety, this verse alludes as well to the ineradicable homology between these two forms of 122Vine andBranches ontological sustenance. "All culture is sacrificial," writes Eric Gans, adding: Culture covers a lot of ground, from bear-baiting to attending a performance of Saint Matthew's Passion, but whether we savagely revel in the victim's sufferings or identify with them in the depths of our soul, culture is the founded on them. And so is the being of those involved in these two fundamental forms of identification. Corresponding to the moral difference between the ritual experiences to which Gans refers is an ontological difference... (shrink)

Les études récentes ont montré que les femmes ont participé, tout au long du Moyen Age, à l’activité économique. Pourtant, leur place dans la production artistique médiévale est généralement ignorée des historiens de l’art, alors même que l’étude de la production d’un artiste ou d’un milieu montre clairement, par les sources et les œuvres, qu’elles ont été présentes à chaque étape du processus de création. La confrontation de la norme à la pratique, par l’analyse de la réglementation de la gilde (...) de Saint-Luc de quatorze villes (Nord, Flandre, Hainaut et Brabant) et des registres d’inscription à la gilde des métiers du livre brugeois, a permis de mettre en perspective les activités des femmes dans les métiers d’art. Elles apparaissent comme maîtresses, ayant passé la maîtrise du métier – et pas seulement de métiers dits féminins –, dirigeant l’atelier, aux côtés du mari ou seules (célibataires ou veuves) apprenties, formant parfois des garçons ou des filles au métier. Elles sont aussi les premières victimes des crises économiques. (shrink)

El propósito de este ensayo es explorar la doctrina política de Platón sobre la democracia a partir del concepto sinergia, es decir, de poder sinérgico, colaboración creativa que reduce los grados de dominación en el régimen político, tal como lo entiende James Craig. Aunque el concepto de poder sinérgico no fue conocido por Platón y ha sido descuidado tanto por la politología como por la filosofía política, considero que es el criterio indispensable para dejar en claro muchas de las ambigüedades (...) del pensamiento platónico. Partimos de la paradójica premisa que Platón pretende crear un autoritarismo absoluto sin dominación. En el desarrollo, se hará evidente que el pensamiento político de Platón está condicionado por unos supuestos que le obligan a aceptar un utopismo irrealizable. Entre esos supuestos destaca la Falacia Angélica, tal como la expone Mortimer Adler. También supone una concepción absolutista de la libertad positiva, así como que la libertad moral atrapada en un estado estancado. La conclusión se resume en un cuadro comparativo entre las características de la utopía platónica y el ideal sinérgico. Destaca en dicho cuadro como Platón toma partido por el autoritarismo virtuoso que condena la transformación política al reino de lo imaginario, en vez de tomar partido por las formas de gobierno compartido. Esto ha dado como resultado histórico la tentación totalitaria de pensar que hay algo mejor que la democracia. Palabras Clave : Platón; política; democracia; sinergia; libertad moral; libertad positiva; falacia angélica. Plato against democracy or the misfortunes of synergyThe purpose of this essay is to explore Plato’s political doctrine on democracy in the light of the concept of synergy, that is to say, of synergic power, which is a creative cooperation that lowers the degrees of domination within the political regime, as is understood by James Craig. Although the concept of synergic power was not known by Plato, and has been neglected by both political science and political philosophy, I consider it to be the indispensable criterion to clarify many ambiguities of Platonic thought. We start from the paradoxical premise that Plato intends to create an absolute authoritarianism without domination. As we progress it will become evident that Plato’s political thought is conditioned by assumptions that make him accept an unfeasible utopianism. Among those assumptions there stands out the Angelical Fallacy, as is exposed by Mortimer Adler. It also implies an absolutistic conception of positive freedom, as well as the idea that moral freedom is trapped in a stagnant state. The conclusion is summed up in a chart comparing the characteristics of Platonic utopia and synergic ideal. In that chart there stands out how Plato takes sides for virtuous authoritarianism, which dooms political transformation to the realm of the imaginary, instead of taking sides for the forms of shared government. This has brought as a historical result the totalitarian temptation of thinking that there might be something better than democracy. Keywords : Plato; Politics; Democracy; Synergy; Moral Freedom; Positive Freedom; Angelical Fallacy. (shrink)