Ḥeleḳ Rishon, kerekh 1. Teshuvot ha-shayakhot le-Miḳra Midrash ṿe-deʻot ṿe-tsoraf la-hen Sefer Minḥat ḳenaʼot le-R. Aba Mari de-Lunil [Haḳdamah-pereḳ 37] -- Ḥeleḳ Rishon, kerekh 2. Miḳra Midrash ṿe-deʻot Teshuvot ha-shayakhot le-Miḳra Midrash ṿe-deʻot ṿe-tsoraf la-hen Sefer Minḥat ḳenaʼot le-R. Aba Mari de-Lunil [pereḳ 38-pereḳ 127] -- Ḥeleḳ sheni. Teshuvot ha-shayakhot le-Masekhet Berakhot ṿe-Seder Zeraʻim -- Ḥeleḳ shelishi. Teshuvot ha-shayakhot le-Masekhet Shabat ṿe-ʻEruvin.

In this paper, we claim that we can only seek to eradicate the stigma associated with the contemporary opioid overdose epidemic when we understand how opioid stigma and the epidemic have co-evolved. Rather than conceptualizing stigma as a parallel social process alongside the epidemiologically and physiologically defined harms of the epidemic, we argue that the stigmatized history of opioids and their use defines the epidemic. We conclude by offering recommendations for disrupting the burden of opioid stigma.

BackgroundIn Saudi clinical settings, benevolent family care that reflects strongly held sociocultural values is commonly used to justify overriding respect for patient autonomy. Because the welfare of individuals is commonly regarded as inseparable from the welfare of their family as a whole, these values are widely believed to obligate the family to protect the welfare of its members by, for example, giving the family authority over what healthcare practitioners disclose to patients about their diagnoses and prognoses and preventing them from (...) making informed decisions about their healthcare.DiscussionFamily dominance over the healthcare decisions of competent patients is ethically problematic when the family prevent healthcare practitioners from disclosing diagnoses and prognoses to patients who have the capacity to consent and make decisions in their own best interests. Thus, the author holds that sociocultural values ought to be respected only when they do not prevent competent patients from knowing their diagnoses and prognoses or prevent them from making their own decisions.ConclusionHealthcare practitioners should not allow patients’ families to control what can or cannot be disclosed to competent patients. This is particularly important when patients are approaching death so that they may address their material and spiritual wishes—among other needs—as they prepare for death. Justification for this position is drawn from the Maqasid Al-Shariah-based Islamic bioethics approach, from which it is possible to argue that the harm of withholding diagnoses and prognoses from patients who are imminently dying outweighs the potential benefits. (shrink)

Religions, ideologies try to give a complete vision of the world a vision containing both its origin, explanation and a “normative kit”: a collection of precepts and rules, which should regulate human activities and behavior. Their synergetic meaning is clear: if embraced by all they allow for development of strong synergetic effects on the social macro scales. These in turn may lead to creation of order and beauty, of intellectual, spiritual and moral development within men and in society. In this (...) consist the elements of their natural—i.e. not explicitly reasoned out—wisdom. However, as they contain also some elements of harmful consequences—at least if they are literally accepted and in a fundamentalist manner practiced—they cannot be universally accepted. But—rejecting them we lose also the important sourcesof natural—or should we say instinctive—wisdom.Could the solution of this contradiction, of this one of the basic human sources of suffering be looked for in the modern science of complexity?Synergetics and the sciences of complex systems in general offer a solid scientific base for a meta-philosophical, universalist intellectual framework. Its offspring the social synergetics offers concrete propositions of optimized social structures. Optimized in the sense of espousing the main synergetic effects with being at the same time free of the negative “side effects” happening when religions or ideologies are the source of synergism.Finally a connection is discussed between the presented ideas and the concept of “love of wisdom”. The term “love of wisdom” may be understood as striving not only to possess a “sound and serene judgment regarding the conduct of life” but also a practical ability to act according to that judgment.This ability may be also expressed using the information-thermodynamic concepts of synergetics. Indeed without the ever continuing negentropy transformation neither survival of a complex system like man or society nor its continuing development—uncovering of all his “hidden potentials” is possible.To assure maximization of this transformation process creation of strong synergetic effects—of reinforcement, of positive feedback—between all human beings—i.e. not excluding any nations, any social groups, and any individuals—are necessary. Acting towards local and global realization of such a structure everywhere on our planet constitutes the essence of social wisdom.Removing all obstacles towards this goal—obstacles existing on the intellectual, emotional and spiritual level—should be one of the most important tasks of various institutions, of state structures, of purified from mythical elements ideologies, of man oriented sciences and above all of the modern universalism.Thus striving towards its realization is an expression of the love of wisdom. Of wisdom once based on the elements of mythos and now regained in the full light of Logos. (shrink)

Purpose. The aim of this article is an analysis of the main versions of the biodeterminist tradition of re­solving the issue of the nature of gender identity, as well as identification of the advantages of the new version of biodeterminism, which involves elements of social constructivism. Theoretical basis. Social norms determine the extent to which a person has the right to independently determine his or her gender identity, and even more so, to change his or her body according to such (...) gender concepts. Social norms regulate gender relations in society and direct the gender behavior of individuals. However, social norms do not create either the human body, or those biological laws, according to which it functions. Originality. The biodetermist theories of the gender were analyzed from the position of "week" social constructivism. The role of social norms as a factor of gender self-certification, as well as a factor of control over social interference in the functioning of human corporeality is considered. The role of modern medicine as an increasingly influential institutional means of control over the functioning of human corporeality, and therefore, indirectly, and for the implementation of gender identity self-identification is revealed. Conclusions. According to the "week" social constructivism the gender emerges as an integral result of biological, psychological and social construction. The role of personality in the design of the gender has historically grown, but this role can never exclude the influence of biological and social factors that are increasingly becoming the nature of biological and social technologies. Personality can become a victim of these technologies, but he/she can program them, or at any rate selectively use, combine, or to some extent adjust existing biological and social technologies. (shrink)

Many Roman Catholic female saints have been virgin martyrs whose lives exemplify a feminine Christian ideal. This article examines the legend of the modern virgin martyr Maria Goretti, a spiritual template whose sainthood can be said to institutionalize violence by defining women as sexualized beings and potential rape victims. The social and psychological effects of the legend of Goretti are discussed as a form of spiritual and sexual terrorism.

This paper is concerned with counterfactual logic and its implications for the modal status of mathematical claims. It is most directly a response to an ambitious program by Yli-Vakkuri and Hawthorne, who seek to establish that mathematics is committed to its own necessity. I demonstrate that their assumptions collapse the counterfactual conditional into the material conditional. This collapse entails the success of counterfactual strengthening, which is controversial within counterfactual logic, and which has counterexamples within pure and applied mathematics. I close (...) by discussing the dispensability of counterfactual conditionals within the language of mathematics. (shrink)

_The Structure of Appearance_ presents a phenomenalist system which constructs enduring visible objects out of qualia. Nevertheless Goodman does not espouse phenomenalism. Why not? In answering this question this paper explicates Goodman’s views about the nature and functions of constructional systems, the prospects of reductionism, and the character of epistemology.

Building on their important findings in The Source of the River, the authors now probe even more deeply into minority underachievement at the college level. Taming the River examines the academic and social dynamics of different ethnic groups during the first two years of college. Focusing on racial differences in academic performance, the book identifies the causes of students' divergent grades and levels of personal satisfaction with their institutions. Using survey data collected from twenty-eight selective colleges and universities, Taming the (...) River considers all facets of student life, including who students date, what fields they major in, which sports they play, and how they perceive their own social and economic backgrounds. The book explores how black and Latino students experience pressures stemming from campus racial climate and "stereotype threat"--when students underperform because of anxieties tied to existing negative stereotypes. Describing the relationship between grade performance and stereotype threat, the book shows how this link is reinforced by institutional practices of affirmative action. The authors also indicate that when certain variables are controlled, minority students earn the same grades, express the same college satisfaction, and remain in school at the same rates as white students. A powerful look at how educational policies unfold in America's universities, Taming the River sheds light on the social and racial factors influencing student success. (shrink)

This chapter contains section titled: Organizing the Notes for On Certainty Groundlessness and Language‐games Searching for Primary Links Between Language and Reality Seeing Logic and Practice Pictures, Propositions and Reality Forms of Life Practices and Parallels Is the Title on Certainty a Happy One? Is on Certainty a Polemic against Moore? Is Wittgenstein's Main Interest in Moore's Propositions the Nature of Nonsense? Does Wittgenstein Say that the Propositions he is Interested in Form a Class, and Does he Say the Same (...) of all of Them? Are Wittgenstein's Propositions Context‐free? What is the Connection between Wittgenstein's Propositions and Logic? Is Wittgenstein Appealing to Primitive, Pre‐linguistic Reactions as the Basis of our Language‐games? What is Meant by the Sureness in Our Language‐games? How are Our Conclusions Related to the Notions of a Form of Life or World‐picture? How do Wittgenstein's Conclusions Differ from Some Classical and Contemporary Views of Our Relation to the World? Rhees's Development of Wittgenstein's Concerns. (shrink)

There is a well-known remark in Wittgenstein's Philosophical Investigations which even some philosophers sympathetic to his work have found very hard to accept. It reads:Philosophy may in no way interfere with the actual use of language;it can in the end only describe it.For it cannot give it any foundation either.It leaves everything as it is. Surely, it is said, that is carrying matters too far. Wittgenstein's hyperbole should be excused as a harmless stylistic flourish.

Thinking about God is historical thinking and that in two senses : the idea of God has a history, and those who think about God think through an historically formed mind. The task of the theologian, is not the attempt to move outside his historicity - such an attempt constitutes a fallacy and not a virtue - but to accept its implications and limitations. Methodologically this means that the theologian must point to the historical perspectives that underlie the idea of (...) God in its development and, in his own constructive thought, must work self-consciously with an historical perspective informed by the psychological and cosmological understanding of his own time. This book centers on that idea which traditionally has been associated with the very godness of God - the idea of divine abso luteness - and puts certain historical, logical, religious and, finally, cosmological questions to it. The roots of that idea lie in Greek thought, which entered Christian theology via the early church fathers; even so, there is much indication, particularly in Patristic trinitarian thought, that the Biblical heritage is pushing theological thinking towards a social or relative concept of divine being (ch. 1). (shrink)

This study looks at the differences and changes observed in the visual design of the covers of French editions of women’s fashion magazines over a period of twenty-one years. To this end, the study aims to identify the changes that can be observed over the years in the design of the covers of the magazines Vogue, Elle, Marie Claire, and Cosmopolitan. However, the main aim of the study is to analyze how these visual signs on the covers of French magazines (...) are designed “differently” and how these signs create a “difference” in comparison to each other. By analyzing these visual elements, the aim of the study is to show the development of design trends and their impact on the visual communication strategies and brand identities of magazines. (shrink)

This Article uses a history of the push for job security in the United States during the late 20th century to assess New Private Law (NPL) theory. The history recounts the rise and fall of common law and statutory approaches to replacing at-will employment with termination for just cause only. Applying NPL theory to that history, the Article argues that NPL theorists’ current approach to defining their topic of study and distinguishing it from public law is inconsistent within and across (...) theories. NPL theorists seek to carve out an area of law where interpersonal morality trumps legal economists’ goal of collective welfare maximization. That conceptual project depends on a coherent and consistent approach to distinguishing private from public law. Ultimately, the Article argues, NPL theorists face a more fundamental problem, however. Regardless of how one categorizes the events in this history, it shows that the common law-derived interpersonal morality at the heart of NPL theory may not strengthen worker protections in the ways at least some of its theorists hope. (shrink)

Visual working memory is a construct hypothesized to store a small amount of accurate perceptual information that can be brought to bear on a task. Much research concerns the construct's capacity and the precision of the information stored. Two prominent theories of VWM representation have emerged: slot-based and continuous-resource mechanisms. Prior modeling work suggests that a continuous resource that varies over trials with variable capacity and a potential to make localization errors best accounts for the empirical data. Questions remain regarding (...) the variability in VWM capacity and precision. Using a novel eye-tracking paradigm, we demonstrate that VWM facilitates search and exhibits effects of fixation frequency and recency, particularly for prior targets. Whereas slot-based memory models cannot account for the human data, a novel continuous-resource model does capture the behavioral and eye tracking data, and identifies the relevant resource as item activation. (shrink)

Rush Rhees, a close friend of Wittgenstein and a major interpreter of his work, shows how Wittgenstein's _On Certainty_ concerns logic, language, and reality – topics that occupied Wittgenstein since early in his career. Authoritative interpretation of Wittgenstein's last great work, _On Certainty_, by one of his closest friends. Debunks misconceptions about Wittgenstein's _On Certainty_ and shows that it is an essay on logic. Exposes the continuity in Wittgenstein's thought, and the radical character of his conclusions. Contains a substantial and (...) illuminating afterword discussing current scholarship surrounding _On Certainty_, and its relationship to Rhees's work on this subject. (shrink)

Hegel’in Jena döneminde zamanın diyalektiği sorununu yalnızca Tinin Fenomenolojisi’nin “Duyusal Kesinlik” bölümünde ele aldığına yönelik genel anlayış, geçtiğimiz yüzyılda orta Jena dönemi derslerine ait el yazmalarının yayımlanmasıyla yeni bir boyut kazanmıştır. 1804-1805 ile 1805-1806 yıllarına ait olan “Jena Sistem taslakları”nda Hegel’in doğanın zamanın üç boyutuna dair kapsamlı bir diyalektik geliştirdiği görülür. Bu çalışmada Christophe Bouton, söz konusu iki sistem taslağında doğanın soyut zamanına ait momentlerin ürettiği sonlu diyalektiğin Hegelci mantıksal ikili sonsuzluk teorisiyle nasıl aşıldığını inceler. Bouton’a göre orta Jena dönemi (...) taslakları sadece Hegel’in düşünsel gelişim sürecine ışık tutmaz, aynı zamanda Hegel’in Berlin döneminde açıkça ortaya koyacağı doğanın zamanı ile Tinin zamanı olarak tarih arasındaki ilişkiyi de temellendirir. Bu bağlamda Heidegger, Koyré ve Bloch gibi yorumcuların aksine Bouton, Hegelci zaman diyalektiğinin kökeninde geçmişin ya da geleceğin önceliği tezini reddeder. Bouton’a göre Hegel felsefesinde zamanın anlamı, zamanın diğer iki boyutundan yalıtılmış olan geçmişte değil, üç zamansal boyutu kendinde içeren somut şimdidedir. Bouton, zaman ve zamana tabi olan hadiselerin yarattığı açmazın yanı sıra, ezeli ve ebedilik ile somut şimdi arasındaki ilişkiyi Jena dönemi ile Berlin dönemine ait dersler ışığında inceler. (shrink)

Growth factor receptor tyrosine kinases (RTKs), such as the fibroblast growth factor receptor (FGFR), play a major role in how cells communicate with their environment. FGFR signaling is crucial for normal development, and its misregulation in humans has been linked to developmental abnormalities and cancer. The precise molecular mechanisms by which FGFRs transduce extracellular signals to effect specific biologic responses is an area of intense research. Genetic analyses in model organisms have played a central role in our evolving understanding of (...) these signal transduction cascades. Genetic studies in the nematode C. elegans have contributed to our knowledge of FGFR signaling by identifying genes involved in FGFR signal transduction and linking their gene products together into signaling modules. This review will describe FGFR-mediated signal transduction in C. elegans and focus on how these studies have contributed to our understanding of how FGFRs orchestrate the assembly of intracellular signaling pathways. BioEssays 23:1120–1130, 2001. © 2001 John Wiley & Sons, Inc. (shrink)

The question of what explains individual differences in expertise within complex domains such as music, games, sports, science, and medicine is currently a major topic of interest in a diverse range of fields, including psychology, education, and sports science, to name just a few. Ericsson and colleagues’ deliberate practice view is highly influential perspective in the literature on expertise and expert performance—but is it viable as a testable scientific theory? Here, reviewing more than 25 years of Ericsson and colleagues’ writings, (...) we document critical inconsistencies in the definition of deliberate practice, along with apparent shifts in the standard for evidence concerning deliberate practice. We also consider the impact of these issues on progress in the field of expertise, focusing on the empirical testability and falsifiability of the deliberate practice view. We then discuss a multifactorial perspective on expertise, and how open science practices can accelerate progress in research guided by this perspective. (shrink)

In public and political practice, argumentation involves verbal manipulations, which have not been sufficiently studied in modern argumentation theory. This paper proposes to analyse such manipulations as speech acts, by means of the pragmadialectical theory of argumentation.

Objectives: To investigate the extent to which family physicians in Lithuania inform their patients about possible side-effects when a common treatment is proposed. To examine the relation between physicians’ estimation of the severity and frequency of these side-effects and their willingness to inform patients. To identify the reasons for informing or not informing the patients.Methods: A questionnaire, presenting three hypothetical cases involving decisions about ordinary medical treatments and a series of general questions about information about side-effects, was distributed to 500 (...) Lithuanian GPs. The response rate was 42%.Results: The respondents differed considerably with regard to their willingness to inform patients about side-effects, but they informed their patients significantly more if the side effect was considered to be common and serious, than in cases when it was considered to be rare and trivial. The majority of the respondents informed their patients primarily to enable them to react appropriately to the side-effects in question. The major reason for not informing was that the side-effects were considered too rare to be relevant to the patient’s decision-making.Conclusion: Information, given to patients about side-effects by Lithuanian GPs, is not in accordance with the principle of respect for patients’ autonomy and requirements of Lithuanian legislation. (shrink)

This article examines interactivity using the concept of dialogic relationships introduced by Russian philosopher Mikhail Bakhtin and the concept of transtextuality, proposed by French literary theorist Gérard Genette. These concepts help to reveal two parallel strata of interactivity: the stratum of interactivity between the viewer and the message and the stratum of interactivity that exists inside the message and its surrounding. It concludes that interactivity can be conceived as a relation and that the message is a co-creation. The study contributes (...) to the theory of interactivity, which challenges the existing – and rather limited – advertising theories and offers an alternative Bakhtinian perspective on the phenomenon of interactivity. (shrink)