Neuroimaging studies on moral decision-making have thus far largely focused on differences between moral judgments with opposing utilitarian (well-being maximizing) and deontological (duty-based) content. However, these studies have investigated moral dilemmas involving extreme situations, and did not control for two distinct dimensions of moral judgment: whether or not it is intuitive (immediately compelling to most people) and whether it is utilitarian or deontological in content. By contrasting dilemmas where utilitarian judgments are counterintuitive with dilemmas in which they are intuitive, we (...) were able to use functional magnetic resonance imaging to identify the neural correlates of intuitive and counterintuitive judgments across a range of moral situations. Irrespective of content (utilitarian/deontological), counterintuitive moral judgments were associated with greater difficulty and with activation in the rostral anterior cingulate cortex, suggesting that such judgments may involve emotional conflict; intuitive judgments were linked to activation in the visual and premotor cortex. In addition, we obtained evidence that neural differences in moral judgment in such dilemmas are largely due to whether they are intuitive and not, as previously assumed, to differences between utilitarian and deontological judgments. Our findings therefore do not support theories that have generally associated utilitarian and deontological judgments with distinct neural systems. (shrink)

Research on social influences often distinguishes between social and quality incentives to ascribe meaning to the value that popularity conveys. This study examines the neural correlates of those incentives through which popularity influences preferences. This research reports an functional magnetic resonance imaging experiment and a behavioral task in which respondents evaluated popular products with three focus perspectives; unspecified focus, focus on social aspects, and focus on quality. The results show that value derived with a social focus reflects inferences of approval (...) and reward value, and positively affects preferences. Value derived with a quality focus reflects inferences of quality and negatively affects preferences. This study provides evidence of two distinct inferential routes on both a neurological level, represented by different regions in the brain, and a behavioral level. These results provide the first evidence that a single popularity cue can in different ways influence the value derived from product popularity. (shrink)

In written and spoken communications, figures of speech (e.g., metaphors and synecdoche) are often used as an aid to help convey abstract or less tangible concepts. However, the benefits of using rhetorical illustrations or embellishments in visualization have so far been inconclusive. In this work, we report an empirical study to evaluate hypotheses that visual embellishments may aid memorization, visual search and concept comprehension. One major departure from related experiments in the literature is that we make use of a dual-task (...) methodology in our experiment. This design offers an abstraction of typical situations where viewers do not have their full attention focused on visualization (e.g., in meetings and lectures). The secondary task introduces “divided attention”, and makes the effects of visual embellishments more observable. In addition, it also serves as additional masking in memory-based trials. The results of this study show that visual embellishments can help participants better remember the information depicted in visualization. On the other hand, visual embellishments can have a negative impact on the speed of visual search. The results show a complex pattern as to the benefits of visual embellishments in helping participants grasp key concepts from visualization. (shrink)

Background Scientific and technological advancements in mapping and understanding the interrelated pathways through which biological and environmental exposures affect disease development create new possibilities for detecting disease risk factors. Early detection of such risk factors may help prevent disease onset or moderate the disease course, thereby decreasing associated disease burden, morbidity, and mortality. However, the ethical implications of screening for disease risk factors are unclear and the current literature provides a fragmented and case-by-case picture. Methods To identify key ethical considerations (...) arising from the early detection of disease risk factors, we performed a systematic scoping review. The Scopus, Embase, and Philosopher’s Index databases were searched for peer-reviewed, academic records, which were included if they were written in English or Dutch and concerned the ethics of (1) early detection of (2) disease risk factors for (3) disease caused by environmental factors or gene-environment interactions. All records were reviewed independently by at least two researchers. Results After screening 2034 titles and abstracts, and 112 full papers, 55 articles were included in the thematic synthesis of the results. We identified eight common ethical themes: (1) Reliability and uncertainty in early detection, (2) autonomy, (3) privacy, (4) beneficence and non-maleficence, (5) downstream burdens on others, (6) responsibility, (7) justice, and (8) medicalization and conceptual disruption. We identified several gaps in the literature, including a relative scarcity of research on ethical considerations associated with environmental preventive health interventions, a dearth of practical suggestions on how to address expressed concerns about overestimating health capacities, and a lack of insights into preventing undue attribution of health responsibility to individuals. Conclusions The ethical concerns arising with the early detection of risk factors are often interrelated and complex. Comprehensive ethical analyses are needed that are better embedded in normative frameworks and also assess and weigh the expected benefits of early risk factor detection. Such research is necessary for developing and implementing responsible and fair preventive health policies. (shrink)

The aim of this study was to understand how mothers experienced midwives' uncaring behaviour and actions during birth. Sixty-seven first-time mothers took part in the study, in which data were collected through interview. The interview text was analysed using hermeneutic text analysis. Nearly half of the mothers interviewed (n = 32) said that midwives did not care for them. The findings show that midwives' behaviour was humiliating when they ignored mothers and held them in contempt. The mothers felt further humiliated (...) when the midwives did not believe them, treated their bodies in a careless manner and tended to put blame on them. Through their behaviour and actions, some midwives have shown that they no longer have a caring attitude as an element of their professional practice and that they have ignored ethics by offending mothers' sense of dignity. (shrink)

BackgroundThe UN Convention on the Rights of Persons with Disabilities, and the reformed guardianship law in Germany, require that persons with a disability, including people with dementia in Alzheimer’s disease (PwAD), are supported in making self-determined decisions. This support is achieved through communication. While content-related communication is a deficit of PwAD, relational aspects of communication are a resource. Research in supported decision-making (SDM) has investigated the effectiveness of different content-related support strategies for PwAD but has only succeeded in improving understanding, (...) which, although one criterion of capacity to consent, is not sufficient to ensure overall capacity to consent. The aim of the ‘spatial intervention study’ of the DECIDE project is to examine an innovative resource-oriented SDM approach that focuses on relational aspects. We hypothesise that talking to PwAD in their familiar home setting (as opposed to a clinical setting) will reduce the complexity of the decision-making process and enhance overall capacity to consent. MethodsPeople with a suspected or confirmed diagnosis of dementia in Alzheimer’s disease will be recruited from two memory clinics (N = 80). We will use a randomised crossover design to investigate the intervention effect of the decision-making place on capacity to consent. Besides reasoning capacity, which is part of overall capacity to consent and will be the primary outcome, various secondary outcomes (e.g., other aspects of capacity to consent, subjective task complexity, decisional conflict) and suspected moderating or mediating variables (e.g., meaning of home, demographic characteristics) will be assessed.DiscussionThe results of the study will be used to develop a new SDM strategy that is based on relational resources for PwAD. If a change in location achieves the anticipated improvement in capacity to consent, future research should focus on implementing this SDM strategy in a cost-effective manner in clinical practice.Trial registration: DRKS00030799. (shrink)

Progressive supranuclear palsy is a movement disorder with prominent tau neuropathology. Brain diseases with abnormal tau deposits are called tauopathies, the most common of which is Alzheimer's disease. Environmental causes of tauopathies include repetitive head trauma associated with some sports. To identify common genetic variation contributing to risk for tauopathies, we carried out a genome-wide association study of 1,114 individuals with PSP and 3,247 controls followed by a second stage in which we genotyped 1,051 cases and 3,560 controls for the (...) stage 1 SNPs that yielded P ≤ 10-3. We found significant previously unidentified signals associated with PSP risk at STX6, EIF2AK3 and MOBP. We confirmed two independent variants in MAPT affecting risk for PSP, one of which influences MAPT brain expression. The genes implicated encode proteins for vesicle-membrane fusion at the Golgi-endosomal interface, for the endoplasmic reticulum unfolded protein response and for a myelin structural component. © 2011 Nature America, Inc. All rights reserved. (shrink)

Animal welfare in pig production is frequently a topic of debate and is sensitive in nature. This debate is partly due to differences in values, forms, convictions, interests and knowledge among the stakeholders that constitute differences among their frames of reference with respect to pigs and their welfare. Differences in frames of reference by stakeholder groups are studied widely, but not specifically with respect to animal behaviour or welfare. We explored this phenomenon using a qualitative behaviour assessment . Participating stakeholders (...) were classified into two expert groups consisting of pig farmers and animal scientists and a lay-group consisting of urban citizens . The stakeholders were asked to observe the behaviour of a specific pig in each of the nine videos and to assign a score for each video using 21 predefined terms describing the mood, such as ‘happy’ or ‘irritated’. They were asked to complete two additional questionnaires to obtain information on their frames of reference. Results from the QBA showed that the pig farmers observed the behaviour of pigs more positively than the urban citizens and the animal scientists. This was evident from the consistently higher scores on the positive terms to assess pig behaviour. The questionnaires revealed that the farmers had a different frames of reference regarding pigs and different understanding of welfare, which might explain the differences in assessment. In a follow-up stakeholder workshop, which focussed on differences in observation, QBA showed to be an effective tool to stimulate mutual learning among stakeholders, which is necessary to find shared solutions. (shrink)

Introduction: Time and the shared world -- The "subject" of inquiry -- Mineness and the practical first-person -- Being and otherness: Sartre's critique -- Heideggerian aprioricity and the categories of being -- The temporality of care -- Fursorge: acknowledging the other Dasein -- Authenticity, inauthenticity, and the extremes of Fursorge -- Conclusion.

Written by two of the leading figures in the field, this is a lucid and systematic introduction to semantics as applied to transformational grammars of the ...

In this response to Johnson, Oh reaffirms the scholarly vision of Kelsay and Twiss, elaborates upon Muslim perspectives on human rights, and questions the emphasis on violent humanitarian interventions as part of the Responsibility to Protect mandate. Oh suggests that, in light of the historical relationship between Muslim and non-Muslim states and the aftermath of the second Iraq War, more consideration be given to the rebuilding of Muslim-majority societies. Oh also highlights the concept of duty as a religiously based ideal (...) to which governments of Muslim nations ought to be held. (shrink)

Kevin Smith's utilitarian argument against homeopathy1 is flawed because he did not review and refute the relevant basic science literature on ultra-high dilutions. He also failed to appreciate that allopathic medicine is based on a deductive-nomothetic method and that homeopathic medicine is based on an inductive-idiographic method, and thus that the implications for clinical research are very different. His misunderstanding of provings and of the holism of homeopathic medicine also demonstrated his failure to understand the history, philosophy and method of (...) homeopathy. Finally, I questioned the value of introducing ethical judgment into an ongoing scientific debate. (shrink)

The suggestion that analytic isomorphism should be rejected applies especially to the domain of speech perception because (1) the guiding assumption that solving the lack of invariance problem is the key to explaining speech perception is a form of analytic isomorphism, and (2) after nearly half a century of research there is virtually no empirical evidence of isomorphism between perceptual experience and lower-level processing units.

. Björn Lindbloms account of the emergence of phonemic structure is a central reference point in contemporary discussions of the emergence of language. I argue that there are two distinct, and largely orthogonal conceptions of emergence implicit in Lindbloms account. According to one conception (causal emergence), the process by which minimal pairs are generated is crucial to the claim that phonemic structure is emergent; according to the other conception (analytic emergence), the fact that segments are an abstraction from the physical (...) signal is what is crucial to the description of phonemic structure as emergent. The purpose of distinguishing rather than conflating these two conceptions of emergence is not in the first instance to criticize Lindbloms account or to force us to choose between the two conceptions for consistency, but rather to give us a more detailed purchase on the notoriously thorny concept of emergent explanation. (shrink)

Young single women's and men's cognitive scripts for the event “a first date” were examined to determine their content and to test for hypothesized differences in behavioral expectations. Participants were asked to list 20 expected actions involved in a first date for a woman and for a man. High agreement among participants was found for the content and sequence of actions that hypothetically would occur on a first date. The respondents listed a total of 19 different actions for women, and (...) 27 for men. The scripts for women and men differed significantly. The scripts for women emphasized the private sphere ; the scripts for men focused on control of the public domain. Gender roles were more prevalent in experienced daters' scripts. The results indicate that young adults' interpersonal scripts for dating maintain the traditional gender-power ratio. (shrink)

This article presents an artistic and political experiment as an effort to advance democratic transactions in the life sciences. Artists built a ‘gender democratic labyrinth’ in Maastricht, in which scientists, women’s groups, people in general, artists, philosophers, politicians, journalists, clinical geneticists and many others interacted and negotiated on the creation of human embryos for medical-scientific research. By taking a gender perspective on the process of democratizing science, we aimed to create a space in which alterity and difference are constitutive elements (...) in the public exchanges on science and technology. The idea to build a labyrinth was theoretically based on the notion of agonistic democracy - in which pluralism is the result of contestations and divisions - and on a notion of science and technology as being contextualized and socialized. (shrink)

This essay is a critical review of two recent collections, Feminism and Foucault: Reflections on Resistance, edited by Irene Diamond and Lee Quinby and Feminism as Critique: On the Politics of Gender, edited by Seyla Benhabib and Drucilla Cornell. While the collections differ in their manner of addressing the critical sources that have inspired them-the former relying upon a single theorist, the latter attempting to move through some of the philosophical history that constitutes our present theoretical terrain-both attempt to (...) think through and thus revisualize some of the categories of difference which we have inherited. Though the best essays from these collections are celebrated for demonstrating how "feminism as critique" can work to move us toward a clearer and more inclusive feminist theory, questions are raised about what the inattention to race in these volumes suggests about our own role in the construction of power and knowledge, and the erasures that help to secure them both. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Philosophy and Literature 26.2 (2002) 405-414 [Access article in PDF] Nihilism in Seamus Heaney Irene Gilsenan Nordin I WISH TO BEGIN WITH THE WORDS of Nietzsche's madman as he makes his famous appearance, running into the crowded marketplace in the bright morning with his lit lantern in his hand, crying out his proclamation of the death of God: "'Where has God gone?' he [cries]. 'I shall tell you. (...) We have killed him—you and I. We are all his murderers.'" He calls out in despair to the bemused and indifferent crowd his rhetorical questions: How were we able to drink up the sea? Who gave us the sponge to wipe away the entire horizon? What were we doing when we unchained the earth from its sun? Whither is it moving now? Away from all suns? Are we not plunging continually? Backward, sideward, forward, in all directions? Is there still any up or down? Are we not straying as through an infinite nothing? 1These words of the madman express the abyss of despair experienced on the realization that God is dead, the state of desolation which articulates what Nietzsche himself understood to be the consequences of the triumph of the Enlightenment. But these words of despair sum up more than that; they sum up the underlying problems of Nietzsche's age, and indeed our age: the basic mistrust of all previously held systems of value; the collapse of all ordering principle; and the erosion of the authority of tradition. In other words, reason has revealed the inadequacy of tradition, and has itself lost the ability to provide us with [End Page 405] any reliable means of evaluation—since any such evaluation must be based on the very principles which are themselves under attack.This stark realization of the absence of all sense of meaning in values previously held to be true leads to the condition that Nietzsche calls "nihilism," (Latin nihil, "nothing"), the condition that he considered to be the central problem of Modernity. This condition, Nietzsche believed, is brought about by the realization of three factors: first, the loss of faith in what he calls a "'meaning' in all events," a loss which contributes to an experience of aimlessness; second, the realization that there is no inherent pattern to the world or to history that can lend universal coherence; and third, the loss of faith in the existence of a stable world of being which can be evaluated according to steadfast, enduring principles. The rejection of these three categories, which Nietzsche terms "aim," "unity," and "being," leads to an experience of a world that appears "valueless," in other words, the experience of nihilism. 2Nietzsche, whose thought was considered by Heidegger to be the "final thought of Western metaphysics," 3 is seen as a heralding voice of postmodernism. 4 In this respect, Nietzsche's "death of God" can be seen to be about the death of modernist philosophical presuppositions, the death of the logocentric metaphysics of presence. But, parallel with the notion of crisis that Nietzsche's announcement of the death of God expresses and the ensuing critique of "metanarratives" which his thought has helped to give rise to, 5 Nietzsche's declaration of crisis can also be seen as a statement of faith. His interpretation of the problems of our age, while on the one hand "negatively" proclaiming the death of God and denying the possibility of shared meaning—or in Lyotard's terms "the consensus of a taste which would make it possible to share collectively the nostalgia for the unattainable" (p. 81), can, on the other hand, be viewed in a more "positive" light. The term "nihilism" itself, as Nietzsche has shown us, is ambiguous, comprising both the concepts of what he termed "active nihilism" and "passive nihilism," which involves a complex interplay between the dual forces of affirmation and negation (WP, p. 22).As the Italian philosopher, Gianni Vattimo, points out, the most general distinction between these forces can be seen in terms of "strength of spirit," where nihilism is considered as both "a sign (Zeichen) of the strengthened power... (shrink)

Their treatment of such human rights political participation, freedom of conscience, and religious toleration demonstrate, Oh says, that Islam should have a ...

In this piece I respond to questions and criticisms raised by commentators on my recent book, Existential Flourishing: A Phenomenology of the Virtues. I argue for...

El objetivo principal del presente artículo es explorar el papel de los Códigos Éticos en el contexto turístico. Para ello, se realiza un análisis de la aplicación de Códigos Éticos en el sector turístico a partir de examinar y categorizar el contenido y sistema de gestión de códigos éticos turísticos existentes en el estado español. A partir de este primer análisis, se realiza un focus group y entrevistas en profundidad a académicos y profesionales turísticos para obtener una aproximación crítica a (...) los contenidos y del sistema de gestión para, por un lado, revisar el contenido de los códigos éticos turísticos y, por otro lado, su gestión para convertirlos en elementos de transformación de la realidad turística. A partir de ello, se ofrecen una serie de bases y recomendaciones para la elaboración de un Código Ético en el contexto de un destino turístico. (shrink)

‘Pencil’, ‘Tiger’, ‘Christianity’. What kind of reference (if any) do these terms have? Do they have the same semantics? In his celebrated The Meaning of ‘Meaning’ (1975), Hilary Putnam suggests so when arguing that they have externalist semantics. However, this claim is highly controversial. A lengthy discussion has been going on the matter. So far, neither Putnam’s nor other defenses of Externalism proposed within this debate have actually succeeded in showing that the terms at stake (and their likes) are semantically (...) on a par. Here I examine further options left to the externalist. I conclude that, still, none is a viable alternative for defending that Externalism applies to the mentioned terms (and their likes). (shrink)