Philosophical discussions on causal inference in medicine are stuck in dyadic camps, each defending one kind of evidence or method rather than another as best support for causal hypotheses. Whereas Evidence Based Medicine advocates the use of Randomised Controlled Trials and systematic reviews of RCTs as gold standard, philosophers of science emphasise the importance of mechanisms and their distinctive informational contribution to causal inference and assessment. Some have suggested the adoption of a pluralistic approach to causal inference, and an inductive (...) rather than hypothetico-deductive inferential paradigm. However, these proposals deliver no clear guidelines about how such plurality of evidence sources should jointly justify hypotheses of causal associations. We here develop such guidelines by first giving a philosophical analysis of the underpinnings of Hill’s viewpoints on causality. We then put forward an evidence-amalgamation framework adopting a Bayesian net approach to model causal inference in pharmacology for the assessment of harms. Our framework accommodates a number of intuitions already expressed in the literature concerning the EBM vs. pluralist debate on causal inference, evidence hierarchies, causal holism, relevance, and reliability. (shrink)

Narrative allegory is distinguished from mythology as reality from symbol; it is, in short, the proper intermedium between person and personification. Where it is too strongly individualized, it ceases to be allegory […]. In the community of scholars of intermedia research, the above quoted citation is commonly regarded as Coleridge’s coining of the term “intermedium” or “intermediality”. However, a short glance at the discursive strategy of his argument emphasizes that his notion of “intermedium” must be closely linked to the poetics (...) and aesthetics of 19th-century romanticism. For the romantic poet, the term of “intermedium” does not point to media relations or intermedia processes but to.. (shrink)

This article sketches an idealized strategy for the identification of neural correlates of consciousness. The proposed strategy is based on a state space approach originating from the analysis of dynamical systems. The article then focuses on one constituent of consciousness, phenomenal awareness. Several rudimentary requirements for the identification of neural correlates of phenomenal awareness are suggested. These requirements are related to empirical data on selective attention, on completely intrinsic selection and on globally unconscious states. As an example, neuroscientific findings on (...) synchronized γ activity are categorized according to these requirements. (shrink)

Wormald proposes to remove the anomalous absorption of photons in the light clock by making a relativistic correction for absorption frequencies in the mirrors. This would require different corrections for atoms in mirrors 1 and 2, even though both have the same velocity relative to the observer. A relativistic time transformation by direct velocity dependence of time rate is different from a transformation between clocks with Lorentz-invariant proper time readings. With ascription of an invariant proper time to the photon clock, (...) one loses its property of directly illustrating the relativistic time transformation. (shrink)

As digital media becomes more central to the lives of adolescents, it also becomes increasingly relevant for their sexual communication. Sexting as an important image-based digital medium provides opportunities for self-determined digital communication, but also carries specific risks for boundary violations. Accordingly, sexting is understood either as an everyday, or as risky and deviant behavior among adolescents. In the affectedness of boundary violations gender plays an important role. However, it is still unclear to what extent digital sexual communication restores stereotypical (...) gender roles and restrictive sexuality norms or, alternatively, enables new spaces of possibility. In this sense, current research points to a desideratum regarding adolescents’ orientations toward sexting as a practice between spaces of possibility and boundary violations. This paper discusses the possibilities, but also the risks, of intimate digital communication among adolescents. The main question is, how adolescents themselves perceive sexting practices and how they position themselves between both spaces for possibility and for the exchange of unwanted sexual content. For this purpose, orientations toward normalities and gender of students are reconstructed. To answer these questions, twelve single-sex, group discussions were carried out with students aged 16 and 17 at five different secondary schools in northern Germany. A total of 20 boys and 22 girls took part. The group discussions were structured by a narrative generating guideline. The analysis draws its methodology from the Documentary Method, regarding implicit and explicit forms of knowledge and discourse. It results in a typology of three types with different orientations. The study shows, that most of the students consider sexting to be a risky practice; only one type shows normality in the use of sexting. At the same time, some of the young people are interested in experimenting with image-based intimate digital communication. Further, gender differences in use and affectedness are also documented. In this way, orientations toward gender stereotypes “favor” both the attribution of responsibility to girls, and overlook the responsibility of students who perpetrated the boundary violation. The orientations of adolescents should be taken more into account in research as well as in educational programs for the prevention of sexual violence. (shrink)

In this essay, we aim to provide an overview of the periodic table’s origins and history, and of the elements which conspired to make it chemistry’s most recognisable icon. We pay attention to Mendeleev’s role in the development of a system for organising the elements and chemical knowledge while facilitating the teaching of chemistry. We look at how the reception of the table in different chemical communities was dependent on the local scientific, cultural and political context, but argue that its (...) eventual universal acceptance is due to its unique ability to accommodate possessed knowledge while enabling novel predictions. Furthermore, we argue that its capacity to unify apparently disconnected phenomena under a simple framework facilitates our understanding of periodicity, making the table an icon of aesthetic value, and an object of philosophical inquiry. Finally, we briefly explore the table’s iconicity throughout its representations in pop art and science fiction. (shrink)

According to the objective Bayesian approach to inductive logic, premisses inductively entail a conclusion just when every probability function with maximal entropy, from all those that satisfy the premisses, satisfies the conclusion. When premisses and conclusion are constraints on probabilities of sentences of a first-order predicate language, however, it is by no means obvious how to determine these maximal entropy functions. This paper makes progress on the problem in the following ways. Firstly, we introduce the concept of a limit in (...) entropy and show that, if the set of probability functions satisfying the premisses contains a limit in entropy, then this limit point is unique and is the maximal entropy probability function. Next, we turn to the special case in which the premisses are categorical sentences of the logical language. We show that if the uniform probability function gives the premisses positive probability, then the maximal entropy function can be found by simply conditionalising this uniform prior on the premisses. We generalise our results to demonstrate agreement between the maximal entropy approach and Jeffrey conditionalisation in the case in which there is a single premiss that specifies the probability of a sentence of the language. We show that, after learning such a premiss, certain inferences are preserved, namely inferences to inductive tautologies. Finally, we consider potential pathologies of the approach: we explore the extent to which the maximal entropy approach is invariant under permutations of the constants of the language, and we discuss some cases in which there is no maximal entropy probability function. (shrink)

We study questionnaire responses to situations in which sacrificing one life may save many other lives. We demonstrate gender differences in moral judgments: males are more supportive of the sacrifice than females. We investigate a source of the endorsement of the sacrifice: antisocial preferences. First, we measure individual proneness to spiteful behavior, using an experimental game with monetary stakes. We demonstrate that spitefulness can be sizable—a fifth of our participants behave spitefully—but it is not associated with gender. Second, we find (...) that gender is consistently associated with responses even when we account for individual differences in the propensity to spitefulness. (shrink)

Epistemic scoring rules are the en vogue tool for justifications of the probability norm and further norms of rational belief formation. They are different in kind and application from statistical scoring rules from which they arose. In the first part of the paper I argue that statistical scoring rules, properly understood, are in principle better suited to justify the probability norm than their epistemic brethren. Furthermore, I give a justification of the probability norm applying statistical scoring rules. In the second (...) part of the paper I give a variety of justifications of norms for rational belief formation employing statistical scoring rules. Furthermore, general properties of statistical scoring rules are investigated. Epistemic scoring rules feature as a useful technical tool for constructing statistical scoring rules. (shrink)

O presente trabalho examina os aspectos históricos da extração do óleo de canela-sassafrás (Ocotea pretiosa Mez), rico em safrol, no Alto e Médio Vale do Itajaí, a partir de 1940, por iniciativa de Otto Grimm, no município de Rio do Sul. Apresenta-se o tema no contexto da memória química em Santa Catarina, e discutem-se os procedimentos utilizados, e principalmente os motivos que levaram tal indústria incipiente a não se converter em uma indústria de química fina. Para tanto, são apresentados alguns (...) dados pertinentes à química do safrol, indicando que tal indústria poderia ter evoluído, bem como os aspectos econômicos e sociais que, ao lado da proibição do corte da canela-sassafrás, levaram em 1990 à extinção definitiva dessa "química fina que poderia ter sido". (shrink)

Critic, poet and philosopher Friedrich von Schlegel (1772–1829) was a leading figure of German Romanticism. In the two years before his untimely death, he wrote three cycles of lectures intended as part of a larger project to lay the foundations of a new general philosophy. Two of these cycles, 'Philosophie des Lebens' (given in 1827, published 1828) and 'Philosophie des Sprache und des Wortes' (given in December 1828 and published posthumously), are reissued here in an 1847 English translation. The (...) first presents Schlegel's understanding of philosophy as independent of theology or politics, concerned with the 'inner spiritual life' of humankind. The second explores the nature of communication through language and art. Schlegel argues that full human consciousness cannot be restored by Enlightenment science, but only by divine revelation and redemption. He offers no ready-made solutions, but encourages his listeners to develop their own responses to these questions. (shrink)

Critic, poet and philosopher Friedrich von Schlegel was a leading figure of German Romanticism. In the two years before his untimely death, he wrote three cycles of lectures intended as part of a larger project to lay the foundations of a new general philosophy. Two of these cycles, 'Philosophie des Lebens' and 'Philosophie des Sprache und des Wortes', are reissued here in an 1847 English translation. The first presents Schlegel's understanding of philosophy as independent of theology or politics, (...) concerned with the 'inner spiritual life' of humankind. The second explores the nature of communication through language and art. Schlegel argues that full human consciousness cannot be restored by Enlightenment science, but only by divine revelation and redemption. He offers no ready-made solutions, but encourages his listeners to develop their own responses to these questions. (shrink)

The chemist Max von Pettenkofer studied with Justus von Liebig, and after leaving Giessen in 1844 did not immediately find an academic position. During the period 1844/1845 he wrote a cycle of 16 Chemical Sonnets, but published them only in 1886. The Sonnets have with few exceptions a historiographical character. We present a translation of the Sonette into Portuguese as well as commentaries about their content and their philosophical significance. We also comment rather briefly on Pettenkofer’s career as an empirical (...) chemist and later as a somewhat heterodox hygienist. (shrink)

Augmented Reality (AR) is commonly defined as a digital layer of information viewed on top of the physical world through a smartphone, tablet or eyewear. Increasingly, this understanding of AR is shifting to a dynamic framework of ‘smart things’, including wearable technology, sensors and artificial intelligence (AI), with the ability to intercede in key moments and to deliver contextual and meaningful experiences. The things that come into context are the logical next steps in an evolutionary development towards computers that are (...) better able to show empathy in relation to people: even more human-oriented, anticipative and ubiquitous. Thus, this outsourcing of meaning to empathic technologies points to one of the fundamental questions concerning the relation of human and technology – the nature of the trust that users place in technology. (shrink)

It can scarcely be said to be a self-contradictory property to be in two places at the same time any more than for an object to be at two times in the same place. The perplexities of the quantum theory of energy sometimes seem to suggest that the possibility ought not to be overlooked; …A. S. Eddington, Space, Time and Gravitation, Cambridge, 1920There are three elements involved in physical time. The most primitive of the three is the fact of extension (...) in time. We express this fact by saying that things “endure” in time, or by saying that the universe is not an event of one moment only. Extension in time is such a fundamental and pervasive element of our experience, that we can hardly define it other than by denotatively indicating it. Time extension is basic to the other two elements of time. (shrink)

1827 hielt Friedrich Schlegel seine Vorlesungen zur "Philosophie des Lebens". Damit beginnt sich der Diskurs der modernen Lebensphilosophie zu manifestieren. Doch diese diskurs-begründende Leistung Schlegels wurde bisher nicht gewürdigt. Deshalb hat Robert Josef Kozljanic hier nun erstmals die entscheidenden Vorlesungen Schlegels ausgewählt, betitelt und herausgegeben. In seinem nachfolgenden Text "Schlegel und die Lebensphilosophie des 21. Jahrhunderts - Eine Manifestation" zieht Kozljanic die Linie weiter. Er greift Schlegels Lebensphilosophie engagiert auf und öffnet sie in Richtung Zukunft. Damit fließen erstmals (...) neue Themen in den lebensphilosophischen Diskurs. Themen, die bisher auf dem Gebiet der Philosophiegeschichte übersehen oder abgedrängt wurden: die wichtige Rolle der Lebensphilosophinnen, die dialogisch-philosophische Grundhaltung, Philosophie als Lebenskunst und Leben-Liebes-Kunst, die Frage der Leibes-Lust-Kultivierung, die Funktion der Lebenserfahrungsvernunft und die Suche nach einem gesellschaftskritischen und zugleich empathisch-lebendigen Ich. (shrink)

This paper presents the contributions of Alcindo Flores Cabral, professor of Chemistry at the Faculdade de Agronomia Eliseu Maciel, nowadays part of the Universidade Federal de Pelotas, to chemistry teaching. It is a contribution almost unknown to the Brazilian chemical community, although recognized as valuable by several renowned chemists abroad, like W. Hückel, G. Charlot, F. Strong, E. Fessenden and others. Cabral’s innovative helical representation is presented in connection not only with contemporary representations, but also an incursion is made into (...) the first helical systems proposed, those of Hinrichs and of Baumhauer. Some comments are made not only on Cabral’s Classificação Natural dos Elementos, published in 1946, but also about other texts he wrote for an efficient chemistry teaching. (shrink)

The readiness potential (RP) is one of the most controversial topics in neuroscience and philosophy due to its perceived relevance to the role of conscious willing in action. Libet and colleagues reported that RP onset precedes both volitional movement and conscious awareness of willing that movement, suggesting that the experience of conscious will may not cause volitional movement (Libet, Gleason, Wright, & Pearl, 1983). Rather, they suggested that the RP indexes unconscious processes that may actually cause both volitional movement and (...) the accompanying conscious feeling of will (Libet et al., 1983; pg. 640). Here, we demonstrate that volitional movement can occur without an accompanying feeling of will. We additionally show that the neural processes indexed by RPs are insufficient to cause the experience of conscious willing. Specifically, RPs still occur when subjects make self-timed, endogenously-initiated movements due to a post-hypnotic suggestion, without a conscious feeling of having willed those movements. (shrink)

In the established space-time coordinate-transformation (STCT) interpretation of special relativity theory, relativistic changes are consequent upon the Lorentz transformation of coordinate clocks and rods between relatively moving systems. In the proposed alternative interpretation, relativistic changes occur only in association with physical interactions, and are direct alterations in the variables of the observed system. Since space-time and momentum-energy are conjugate four-vectors, transformation of a space or time variable of a system is to be expected only if there is a concomitant transformation (...) of the corresponding momentum or energy variable. The Lorentz invariance of the scalar entropy functionS supports the interaction interpretation; timet=f(S) of a macroscopic, entropy clock should give a Lorentz-invariant time measure, and an illustrative entropy clock is discussed. Noninteracting physical processes may be called Clausius processes, in contrast to Lorentz processes for which there is interaction and associated Lorentz transformation. Changes of energy and frequency, withE=hv, are instances of the parallel relativistic transformations. Likewise, the variation with velocity in decay time of mesons follows directly from the relativistic energy transformation of decay products; this relationship is shown for muons by a simple calculation with β-decay theory. (shrink)

Este artigo apresenta a contribuição de Alcindo Flores Cabral (1907-1982) - professor de química da Faculdade de Agronomia Eliseu Maciel, hoje incorporada à Universidade Federal de Pelotas - ao ensino de química, uma contribuição quase desconhecida pela própria comunidade química brasileira, embora reconhecida como relevante por diversos químicos estrangeiros importantes, como W. Hückel, G. Charlot, F. Strong, E. Fessenden e outros. A inovadora representação helicoidal de Cabral é apresentada não só em conexão com representações contemporâneas, mas também inclui-se uma incursão (...) pelos primeiros sistemas helicoidais propostos, os de Hinrichs e de Baumhauer. Apresentam-se alguns comentários não somente sobre a Classificação natural dos elementos, publicada em 1946, mas também sobre outros textos escritos para tornar mais eficaz o ensino de química. (shrink)

. In the context of contemporary life questions, especially that of world peace, this essay first develops the view that truth is essentially scientific truth. Although religion gives insights for living, as science encompasses more and more of human experience it reinforces and modifies religious truths with its own firm knowledge. However, because of several limitations, it is concluded that science alone cannot give a complete account of humanity and the universe. For our first beliefs and principles we must look (...) to other kinds of truth, which are in accord with scientific truth but go beyond scientific method in their justification. (shrink)

Volume: v. 1 General Books publication date: 2009 Original publication date: 1835 Original Publisher: Saunders and Otley Subjects: History History / General ...

PHILOSOPHY OF HISTORY. LECTURE X. On the Christian point of view in the Philosophy of History.— The origin of Christianity, considered in reference to the ...

The statistical aspects of quantum explanation are intrinsic to quantum physics; individual quantum events are created in the interactions associated with observation and are not describable by predictive theory. The superposition principle shows the essential difference between quantum and non-quantum physics, and the principle is exemplified in the classic single-photon two-slit interference experiment. Recently Mandel and Pfleegor have done an experiment somewhat similar to the optical single-photon experiment but with two independently operated lasers; interference is obtained even with beam intensity (...) so small that only one photon is in the apparatus at a time. The result can be understood in terms of the superposition of states; or, in terms of the Uncertainty Principle, which is found to forbid the determination of which of the two lasers is the source of a given photon (if conditions for interference are to obtain). The Mandel-Pfleegor experiment gives a physical argument against the continuous localization of a photon that is assumed in the hidden variable theories and therefore gives further support for the generally accepted view that an observed entity (observed state) is created in the observation event. This aspect of quantum physics implies a subjectivism on the level of individual quantum-level occurrences, since there is in quantum theory no basis for asserting the existence of the event independently of observation of it. Extension of this subjectivism to large scale, non-quantum phenomena falls within the principles of quantum theory; counter considerations that argue against such an extension are noted. (shrink)