Purpose This systematic review aims to identify factors that influence parents’ decisions regarding pediatric diagnostic and predictive genetic testing (DT/PT). Factors are integrated into a conceptual model of decision-making. Implications for genetic counseling, research, and ethics are derived. Methods PubMed, PsychInfo, WebofScience and references of related reviews were searched for original publications between 2000 and 2023. Extracted factors were categorized into an existing model. Results Of 5843 publications, 56 met inclusion criteria. The included studies differentiate between DT, traditional, and expanded (...) PT and describe factors impacting parental decisions on both to have the child genetically tested and to be informed about additional findings. Factors included: 1. benefits/hopes, 2. worries/concerns, 3. values and beliefs, 4. individual circumstances, and 5. emotional states. Conclusion Our work extends an existing empirical decision model of family decisions about genome sequencing to genetic testing in pediatrics in general, adding the categories “individual circumstances” and “emotional states”. The factors can be further integrated into the Health Belief Model; the importance of emotional states is reflected in dual-process theories, such as Fuzzy Trace Theory. Research is required on emotional states, differences between DT and PT, parents’ decisions about result disclosure, and dyadic variables as decision-making predictors. (shrink)

Belief and Truth: A Skeptic Reading of Plato explores a Socratic intuition about belief, doxa -- belief is "shameful." In aiming for knowledge, one must aim to get rid of beliefs. Vogt shows how deeply this proposal differs from contemporary views, but that it nevertheless speaks to intuitions we are likely to share with Plato, ancient skeptics, and Stoic epistemologists.

This book argues that political philosophy is central to early Stoic philosophy, and is deeply tied to the Stoics' conceptions of reason and wisdom. Broad in scope, it explores the Stoics' idea of the cosmic city, their notion of citizen-gods, as well as their account of the law.

Vogt puts forward a novel version of the Guise of the Good: the desire to have one's life go well shapes and sustains mid- and small-scale motivations. Her book lays out a non-relativist version of Protagoras's Measure Doctrine and defends a new realism about good human lives.

The Stoics’ theory of kataleptic impressions looks different once we attend to their analysis of the Sorites paradox. In defending this view, I reject the long-standing assumption that the Stoics develop their theory by focusing on sensory impressions. The Stoic approach to vagueness shows, for example, that non-sensory impressions can be seemingly indistinguishable by belonging to a series. It also draws attention to an understudied dimension of Stoic theory: in aiming to assent only to kataleptic impressions, one aims to avoid (...) not only assent to false impressions but also assent to those that are neither true nor false. (shrink)

In this paper, it is argued the Stoics develop an account of corporeals that allows their theory of bodies to be, at the same time, a theory of causation, agency, and reason. The paper aims to shed new light on the Stoics' engagement with Plato's Sophist . It is argued that the Stoics are Sons of the Earth insofar as, for them, the study of corporeals - rather than the study of being - is the most fundamental study of reality. (...) However, they are sophisticated Sons of the Earth by developing a complex notion of corporeals. A crucial component of this account is that ordinary bodies are individuated by the way in which the corporeal god pervades them. The corporeal god is the one cause of all movements and actions in the universe. (shrink)

The Stoics identify the law with the active principle, which is corporeal, pervades the universe, individuates each part of the world, and causes all its movements. At the same time, the law is normative for all reasoners. The very same law shapes the movements of the cosmos and governs our actions. With this reconstruction of Stoic law, I depart from existing scholarship on whether Stoic law is a set of rules. The question of whether ethics involves a set of rules (...) is rich and fascinating. In the 1970s and 80s, the observation that ancient ethics might do without rules was part of philosophy’s rediscovery of virtue ethics. This debate, however, neglects that Stoic law is a corporeal principle pervading the world. The key puzzle regarding Stoic law, I argue, is how it is possible that the very same law is a corporeal principle in the world and normative for us. (shrink)

In the terms of ancient epistemology, Pyrrho is a dogmatist, not a skeptic, simply on account of putting forward a metaphysical theory. His most contested claim is that things are indifferent, unmeasured, and indeterminate—or, on a competing reconstruction, that things are indifferentiable, unmeasurable, and indeterminable. This paper argues that Pyrrho’s position, which I call Pyrrhonian Indeterminacy, belongs to a rich tradition of revisionist metaphysics that includes ancient atomism, flux metaphysics, Plato’s analysis of becoming, and today’s discussions of indeterminacy and vagueness. (...) This tradition, my argument continues, makes room for a kind of metaphysics that proceeds in epistemological terms. Pyrrho’s indeterminacy claim says that things are indeterminate insofar as they do not have features by reference to which we can determine them to be such-and-such. We should not waver or be inclined to see things one way or another—we should see things, and describe them, as “no more this than that.”. (shrink)

The truth of generics such as ‘ducks lay eggs’ is often taken to be intuitive. For the Stoics, this intuition is flawed. Qua thoughts, they argue, generics are neither true nor false. Qua utterances, generics are not bivalently truth-apt. The Stoics ascribe the following flaw to generics: generics predicate something of a kind that is only true of some instances of the kind and that can only be predicated of ‘somethings.’ Given the Stoic rejection of Forms, forms, and essences, kinds (...) are not somethings. And yet, the Stoics are greatly interested in the fact that generics can seem true to us. Their study is part of a normative approach in logic. The virtues of non-precipitancy and non-randomness, as well as other logical virtues, are needed in order to avoid flawed reasoning, including assent to generics. (shrink)

Contrary to their predecessors, the Stoics put forward a unified notion of cause: a cause is a bodily because-of-which. Against the backdrop of Plato’s and Aristotle’s influential views, this is an original proposal. It involves the rejection of an earlier trend, according to which causes and explanations are closely associated. It also involves a pulling apart of causes and principles. And it comes with a charge against Plato and Aristotle, namely that they introduce a swarm of causes, a turba causarum.

I argue that Plato’s account of hunger and thirst in Republic IV, 437d–439a uncovers a general feature of desire: desire has an unqualified and a qualified dimension. This proposal, which I call Two Dimensions, captures recognizable motivational phenomena: being hungry and aiming to determine what one is hungry for, or wanting to study and still figuring out what field it is that one wants to study. Two Dimensions is a fundamental contribution to the theory of desire. It is compatible, I (...) argue, with the better known premise that desire is for the good, because the objects of paradigmatic desires are inherently valuable. (shrink)

Talk about evil resonates in ways that are culturally inherited. Historical and religious dimensions of “evil” often seem to be front and center. Nevertheless, we argue that it would be too quick to dismiss the study of evil within secular ethics. We defend an outlook that is inspired by ancient ethics—also called virtue ethics—which accepts the so-called Guise of the Good account of motivation. For an agent to be motivated to perform an action, something about the action must look good (...) to her. We argue that evil actions do not constitute exceptions to the Guise of the Good. To preserve this framework, we entertain a privative account of evil, according to which evil is the absence of the good, and yet appears in a positive light to the agent who performs an evil action. We reject the view that evil is quantitatively extreme badness. An account of evil should permit that some instances of evil are from a third person perspective not extremely bad. On this picture, evil is agent-relative; something can be evil relative to one person without being evil relative to another person. Accordingly, several qualities—rather than only one distinctive quality—can make an action evil. (shrink)

In aiming for knowledge, one must aim to get rid of beliefs. Vogt shows how deeply this proposal differs from contemporary views, but that it nevertheless speaks to intuitions we are likely to share with Plato, ancient skeptics, and Stoic epistemologists.

Rachel Barney proposes that Plato’s theory of the tripartite soul is plausibly compared to scientific theories today. I depart from Barney by proposing that the tripartite soul is a model and that its status is hypothetical. And I raise four questions: What follows from the Plato-science comparison, as Barney conceives of it? Which questions emerge if science is looked at in the sophisticated mode that Barney employs in her discussion of Plato? Current science invokes a multitude of subsystems relevant to (...) motivation. Why compare it with tripartition? Stoic psychology may share more fundamental ideas with current science, including the premise that all goings-on in the soul are physiological movements. If tripartition is a model, why would one expect it to account for all dimensions of epistemic activity? (shrink)

Ada Bronowski’s The Stoics on Lekta: All There Is to Say offers a comprehensive reconstruction of the role of lekta in Stoic philosophy. Indeed, as one works one’s way through 496 pages, it is hard...

Sextus Empiricus was the voice of ancient Greek skepticism for posterity. His writings contain the most subtle and detailed versions of the ancient skeptical arguments known as Pyrrhonism, adding up to a distinctive philosophical approach. Instead of viewing philosophy as valuable because of the answers it gives to important questions, Sextus considered the search for answers itself to be fundamental and offered a philosophy centered on inquiry. Assuming the point of view of an active inquirer, Sextus developed arguments concerning conflicting (...) appearances, infinite regress in argument, dogmatic assertion of premises that are insufficiently justified, and many other ideas that fascinated later philosophers of knowledge across the centuries. He provided a unique perspective on topics of enduring relevance such as perception, language, logical consequence, belief, ignorance, disagreement, and induction. -/- While Sextus's importance to epistemology was appreciated by early modern and modern philosophers, he is underrepresented in contemporary discussions. In order to put Sextus back in the center of epistemology, these essays discuss his influence in the history of modern philosophy as well as contemporary engagements with Sextus's version of Pyrrhonian skepticism. The contributors investigate epistemology after Sextus, addressing four core themes of Sextus's skepticism: appearances and perception, the structure of justification and proof, belief and ignorance, and ethics and action. The arguments presented here bridge the divide between contemporary and ancient debates about knowledge and skepticism and will appeal to philosophers interested in epistemology and philosophy of mind as well as those interested in ancient philosophy and the history of philosophy more generally. (shrink)

In ancient philosophy, there is no discipline called “logic” in the contemporary sense of “the study of formally valid arguments.” Rather, once a subfield of philosophy comes to be called “logic,” namely in Hellenistic philosophy, the field includes (among other things) epistemology, normative epistemology, philosophy of language, the theory of truth, and what we call logic today. This entry aims to examine ancient theorizing that makes contact with the contemporary conception. Thus, we will here emphasize the theories of the “syllogism” (...) in the Aristotelian and Stoic traditions. However, because the context in which these theories were developed and discussed were deeply epistemological in nature, we will also include references to the areas of epistemological theorizing that bear directly on theories of the syllogism, particularly concerning “demonstration.” Similarly, we will include literature that discusses the principles governing logic and the components that make up arguments, which are topics that might now fall under the headings of philosophy of logic or non-classical logic. This includes discussions of problems and paradoxes that connect to contemporary logic and which historically spurred developments of logical method. For example, there is great interest among ancient philosophers in the question of whether all statements have truth-values. Relevant themes here include future contingents, paradoxes of vagueness, and semantic paradoxes like the liar. We also include discussion of the paradoxes of the infinite for similar reasons, since solutions have introduced sophisticated tools of logical analysis and there are a range of related, modern philosophical concerns about the application of some logical principles in infinite domains. Our criterion excludes, however, many of the themes that Hellenistic philosophers consider part of logic, in particular, it excludes epistemology and metaphysical questions about truth. Ancient philosophers do not write treatises “On Logic,” where the topic would be what today counts as logic. Instead, arguments and theories that count as “logic” by our criterion are found in a wide range of texts. For the most part, our entry follows chronology, tracing ancient logic from its beginnings to Late Antiquity. However, some themes are discussed in several eras of ancient logic; ancient logicians engage closely with each other’s views. Accordingly, relevant publications address several authors and periods in conjunction. These contributions are listed in three thematic sections at the end of our entry. (shrink)

Our recent publication in Neuroethics re-constructed the perspectives of family caregivers of patients with disorders of consciousness on functional neurodiagnostics. Two papers criticized some of our methodological decisions and commented on some conclusions. In this commentary, we would like to further explain our methodological decisions. Despite the limitations of our findings, which we readily acknowledged, we continue to think they entail valid hypotheses that need further investigation. We conclude that some caregivers with high hopes for the recovery of their loved (...) ones with DOC will most likely not consider results of functional neuroimaging as guiding information for treatment decisions, despite efforts taken to deliver information to them. Caregivers of that type might argue that such test-results are not a reliable source of information for the judgement of whether their loved one is likely going to recover or not. We introduce the concept of epistemic beliefs to formulate this hypothesis and suggest that future qualitative studies in this area should be aware of such beliefs when investigating the effects of functional neurodiagnostics on knowledge communication and shared decision making for patients with DOC. (shrink)

This book is dedicated to clarify ambiguous concepts from the world of creativity and innovation. One of the initial triggers for the development of the book was the perceived ambiguity of the binomials Design vs. Design Thinking and Innovation vs. Invention. Frequently, designers and innovation consultants are questioned by their clients about the relationships between these kind of concepts. Has the second emerged through the first, or vice-verse? Is one part of the other? Where are the similarities and which are (...) the differences? This conceptual incomprehension makes itself noticeable between many ambiguous concepts in the world of innovation and creativity. What is the difference between Radical and Disruptive Innovation? Or is Social Innovation the same as Social Intervention? And regarding Creativity, are Creativity and Creative Thinking the same? In this book the reader will find answers to these kinds of questions and doubts. 28 authors from 10 different countries and cultural backgrounds are questioning current definitions and perceptions, by comparing different sources and ideas, or simply by giving their personal opinions. Some of the authors have an academic background, others a practical one, being either entrepreneurs, working with innovation in companies, or being innovation/design consultants. (shrink)

Wieviel Ethik braucht der Mensch, wieviel Ethik braucht die Wissenschaft? Vor dem aktuellen Hintergrund einer gewandelten Wissenschaftsgesellschaft von hoher Entwicklungsdynamik geht es darum, Anleitung zu ethischer Selbst- und Situationsreflexion zu geben. Denn die spektakulären Errungenschaften nicht nur im Bereich der Biomedizin haben jedenfalls vorübergehend Zonen von moralischer und ethischer Ratlosigkeit geschaffen. Sie eröffnen Spielräume, von denen nicht sicher ist, ob sie genutzt werden dürfen und sollten. Die Empfindlichkeit gegenüber den Nachteilen und Risiken der technisch-wissenschaftlichen Zivilisation ist jedenfalls dort, wo die (...) Möglichkeiten verfügbar sind, so weit gestiegen, dass sich ihre praktische Nutzung längst nicht mehr von selbst versteht. Auch das Recht ist derzeit weder auf der nationalen noch auf der internationalen Ebene in der Lage, überzeugende Handlungsanleitung zu geben. Welche Ziele und Mittel mit den neuen Möglichkeiten aber verfolgt werden dürfen, ist in der Tat eine Frage nach der Legitimität von Bedürfnissen und der Angemessenheit der Mittel. Nicht zuletzt appelliert sie (die Empfindlichkeit gegenüber den Errungenschaften der wissenschaftlich-technischen Gesellschaften?) potentiell auch an die Tugend der Selbstbeschränkung, die vielleicht dort noch wirksam wird, wo andere Steuerungsmechanismen versagen oder zu schwach sind. Diese komplexe Problemlage bei der Suche nach einer neuen Wertordnung an den Grenzen der Anwendung von Forschung und Wissenschaft hat der Ethik derzeit eine unerwartete Konjunktur beschert. (shrink)

This innovative collection showcases the importance of the relationship between translation and experience in premodern science, bringing together an interdisciplinary group of scholars to offer a nuanced understanding of knowledge transfer across premodern time and space. The volume considers experience as a tool and object of science in the premodern world, using this idea as a jumping-off point from which to view translation as a process of interaction between diff erent epistemic domains. The book is structured around four dimensions of (...) translation-between terms within and across languages; across sciences and scientific norms; between verbal and visual systems; and through the expertise of practitioners and translators-which raise key questions on what constituted experience of the natural world in the premodern area and the impact of translation processes and agents in shaping experience. Providing a wide-ranging global account of historical studies on the travel and translation of experience in the premodern world, this book will be of interest to scholars in history, the history of translation, and the history and philosophy of science. (shrink)

BackgroundFunctional neurodiagnostics could allow researchers and clinicians to distinguish more accurately between the unresponsive wakefulness syndrome and the minimally conscious state. It remains unclear how it informs surrogate decision-making.ObjectiveTo explore how the next of kin of patients with disorders of consciousness interpret the results of a functional neurodiagnostics measure and how/why their interpretations influence their attitudes towards medical decisions.Methods and SampleWe conducted problem-centered interviews with seven next of kin of patients with DOC who had undergone a functional HD-EEG examination at (...) a neurological rehabilitation center in Germany. The examination included an auditory oddball paradigm and a motor imagery task to detect hidden awareness. We analyzed the interview transcripts using structuring qualitative content analysis.ResultsRegardless of the diagnostic results, all participants were optimistic of the patients’ meaningful recovery. We hypothesize, that participants deal with the results of examinations according to their belief system. Thus, an unfavorable evaluation of the patient’s state had the potential to destabilize the participant’s belief system. To re-stabilize or to prevent the destabilization of their belief system, participants used different strategies. Participants accepted a “positive” HD-EEG result since it stabilized their belief system.ConclusionWe hypothesize, that a group of next of kin of patients with DOC deals with functional neurodiagnostics results on the basis of the result’s value and their high hope that the patient will recover meaningfully. A psychological mechanism seems to moderate the impact of functional neurodiagnostics on surrogate treatment decisions. (shrink)

The gestural repertoire of captive gorillas contains the so-called “hand-on“ (or “pat-off“) gesture in which one animals puts its flat hand on top of another's head, which often leads to cessation of the receiver's previous activity. We investigate the origins of this gesture and developmental aspects of gesture creation. We further analyze gesture form and use in relation to the age of the sender with special consideration of the reaction of the receiver to better explain the function of the hand-on. (...) The focus of the study is to compare this gesture across different age groups in gorillas in regard to both production and reception and to get insights into possible origins of the gesture. (shrink)

Cet ouvrage cherche à mettre en lumière et reconstituer une manière antique négligée d’analyser la connaissance que l’auteure désigne comme « socratique » (p. 3), comme « pyrrhonienne » (p. 184) ou comme une « lecture sceptique de Platon », et dont elle trouve et analyse les principaux éléments chez Platon, Sextus Empiricus et les stoïciens. Cette lignée est définie comme liant immédiatement les questions épistémologiques à des questions normatives à propos de notre incapa­cité d’examiner nos...

The Cambridge Companion to Ancient Scepticism. R. Bett (Ed.), New York: Cambridge University Press 2010, pp. 380+xii, ISBN 780521697545. -/- The Cambridge Companion to Ancient Scepticism, edited by Richard Bett, consists of an Introduction and fifteen papers written by international authors (three of them have been diligently translated into English by the editor). The volume presents the major figures of ancient skepticism and the major interpretational problems. Separate papers are devoted to Pyrrho of Elis (Svavar Hrafn Svavarsson), Arcesilaus and Carneades (...) (Harald Thorsrud), Aenesidemus (R.J. Hankinson) and Sextus Empiricus (Pierre Pellegrin). Agrippa seems to be the only missing figure on the list. Moreover, we can also find a lot of information about the minor figures of ancient skepticism. Mi-Kyoung Lee presents skeptical ideas in early Greek philosophy and Carlos Levy writes about the later academic skeptics, especially Clitomachus, Philo of Larissa and Cicero. Richard Bett in his Introduction lists the most important problems in interpreting ancient skepticism: What kinds of belief, if any, are open to a skeptic? Can a skeptic allow for choice and action and if so, then how? Is skepticism compatible with an ethical outlook? Is there a real difference between the Academic and Pyrrhonist varieties of skepticism? Casey Perin takes on the first one, Katja Maria Vogt—the second, Richard Bett—the third, and Gisela Striker—the last one. We also have the next five papers presenting other important aspects of ancient skepticism. Paul Woodruff writes about skeptical modes, James Allen about the relation between Pyrrhonism and medical schools, Emidio Spinelli about the critique of specialized sciences, Luciano Floridi about the modern rediscovery of ancient skepticism, and Michael Williams about its Cartesian transformation. The Companion is very rich in content and very up-to-date, presenting the latest hypotheses. Here I would like to discuss the problem of Pyrrho’s place within the skeptical tradition. (shrink)