Results for 'Long-distance dependencies'

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  1.  22
    Long-distance dependencies.Mihoko Zushi - 2001 - New York: Garland.
    This book investigates the theory of locality within the framework of minimalism, with a special focus on restructuring and other related phenomena that exhibit an apparent violation of the strictly local conditions.
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  2.  16
    EEG Correlates of Long-Distance Dependency Formation in Mandarin Wh-Questions.Chia-Wen Lo & Jonathan R. Brennan - 2021 - Frontiers in Human Neuroscience 15.
    Event-related potential components are sensitive to the processes underlying how questions are understood. We use so-called “covert” wh-questions in Mandarin to probe how such components generalize across different kinds of constructions. This study shows that covert Mandarin wh-questions do not elicit anterior negativities associated with memory maintenance, even when such a dependency is unambiguously cued. N = 37 native speakers of Mandarin Chinese read Chinese questions and declarative sentences word-by-word during EEG recording. In contrast to prior studies, no sustained anterior (...)
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  3.  3
    Discourse-based constraints on long-distance dependencies generalize across constructions in English and French.Elodie Winckel, Anne Abeillé, Barbara Hemforth & Edward Gibson - 2025 - Cognition 254 (C):105950.
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  4.  61
    Working memory differences in long-distance dependency resolution.Bruno Nicenboim, Shravan Vasishth, Carolina Gattei, Mariano Sigman & Reinhold Kliegl - 2015 - Frontiers in Psychology 6:126597.
    There is a wealth of evidence showing that increasing the distance between an argument and its head leads to more processing effort, namely, locality effects; these are usually associated with constraints in working memory (DLT: Gibson, 2000 ; activation-based model: Lewis and Vasishth, 2005 ). In SOV languages, however, the opposite effect has been found: antilocality (see discussion in Levy et al., 2013 ). Antilocality effects can be explained by the expectation-based approach as proposed by Levy ( 2008 ) (...)
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  5.  23
    Questions with long-distance dependencies: A usage-based perspective.Ewa Dąbrowska - 2008 - Cognitive Linguistics 19 (3).
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  6. Extending statistical learning farther and further: Long-distance dependencies, and individual differences in statistical learning and language.Jennifer B. Misyak & Morten H. Christiansen - 2007 - In McNamara D. S. & Trafton J. G. (eds.), Proceedings of the 29th Annual Cognitive Science Society. Cognitive Science Society. pp. 1307--1312.
  7.  23
    A verb-frame frequency account of constraints on long-distance dependencies in English.Yingtong Liu, Rachel Ryskin, Richard Futrell & Edward Gibson - 2022 - Cognition 222 (C):104902.
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  8.  49
    Understanding minimalist syntax: lessons from locality in long-distance dependencies.Cedric Boeckx - 2008 - Oxford: Blackwell.
    Understanding Minimalist Syntax introduces the logic of the Minimalist Program by analyzing well-known descriptive generalizations about long-distance dependencies. Proposes a new theory of how long-distance dependencies are formed, with implications for theories of locality, and the Minimalist Program as a whole Rich in empirical coverage, which will be welcomed by experts in the field, yet accessible enough for students looking for an introduction to the Minimalist Program.
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  9.  73
    Functional constraints, usage, and mental grammars: A study of speakers' intuitions about questions with long-distance dependencies.Ewa Dąbrowska - 2013 - Cognitive Linguistics 24 (4):633-665.
  10.  33
    The acquisition of questions with long-distance dependencies.Ewa Dąbrowska, Caroline Rowland & Anna Theakston - 2009 - Cognitive Linguistics 20 (3).
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  11. Production units and production problems in forming long-distance dependencies.K. Bock & J. C. Cutting - 1990 - Bulletin of the Psychonomic Society 28 (6):502-502.
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  12.  40
    Long-Distance Paradox and the Hybrid Nature of Language.Guillermo Lorenzo - 2018 - Biosemiotics 11 (3):387-404.
    Non-adjacent or long-distance dependencies (LDDs) are routinely considered to be a distinctive trait of language, which purportedly locates it higher than other sequentially organized signal systems in terms of structural complexity. This paper argues that particular languages display specific resources (e.g. non-interpretive morphological agreement paradigms) that help the brain system responsible for dealing with LDDs to develop the capacity of acquiring and processing expressions with such a human-typical degree of computational complexity. Independently obtained naturalistic data is discussed (...)
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  13.  56
    Testing the Limits of Long-Distance Learning: Learning Beyond a Three-Segment Window.Sara Finley - 2012 - Cognitive Science 36 (4):740-756.
    Traditional flat-structured bigram and trigram models of phonotactics are useful because they capture a large number of facts about phonological processes. Additionally, these models predict that local interactions should be easier to learn than long-distance ones because long-distance dependencies are difficult to capture with these models. Long-distance phonotactic patterns have been observed by linguists in many languages, who have proposed different kinds of models, including feature-based bigram and trigram models, as well as precedence (...)
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  14.  50
    Customer Loyalty in Recreational Long-Distance Races: Differences Between Novice and Experienced Runners.David Cabello-Manrique, Antonio Fernández-Martínez, Antonio Francisco Roca Cruz, Borja García-García & Alberto Nuviala - 2021 - Frontiers in Psychology 12.
    A growing number of recreational races are being held in different locations, drawing many local and visiting runners. This study examined the relationships between quality, value, satisfaction, and loyalty among runners in a recreational race and examines potential differences in relationships between these constructs based on the runners’ experience. The participants were 985 runners with a mean age of 40.74±9.41years. Validated, reliable ad hoc instruments were used. A multi-group analysis was performed to ascertain the existence of relationships between the constructs (...)
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  15.  13
    Decision Making Strategy and the Simultaneous Processing of Syntactic Dependencies in Language and Music.M. P. Roncaglia-Denissen, Fleur L. Bouwer & Henkjan Honing - 2018 - Frontiers in Psychology 9:172262.
    Despite differences in their function and domain-specific elements, syntactic processing in music and language is believed to share cognitive resources. This study aims to investigate whether the simultaneous processing of language and music share the use of a common syntactic processor or more general attentional resources. To investigate this matter we tested musicians and non-musicians using visually presented sentences and aurally presented melodies containing syntactic local and long-distance dependencies. Accuracy rates and reaction times of participants’ responses were (...)
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  16.  18
    The Influence of Trait Emotion and Spatial Distance on Risky Choice Under the Framework of Gain and Loss.Fuming Xu & Long Huang - 2022 - Frontiers in Psychology 13.
    In the time of the COVID-19 pandemic, people are often faced with uncertain risky choice. Risky choice will be affected by different descriptions of the event’s gain or loss framework, this phenomenon is known as the framing effect. With the continuous expansion and in-depth study of frame effects in the field of risky choice, researchers have found that the are quite different in different situations. People have different interpretations of the same event at different psychological distances, and will also be (...)
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  17.  40
    Photon Flux and Distance from the Source: Consequences for Quantum Communication.Andrei Khrennikov, Börje Nilsson, Sven Nordebo & Igor Volovich - 2014 - Foundations of Physics 44 (4):389-405.
    The paper explores the fundamental physical principles of quantum mechanics (in fact, quantum field theory) that limit the bit rate for long distances and examines the assumption used in this exploration that losses can be ignored. Propagation of photons in optical fibers is modelled using methods of quantum electrodynamics. We define the “photon duration” as the standard deviation of the photon arrival time; we find its asymptotics for long distances and then obtain the main result of the paper: (...)
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  18.  65
    Backward Dependencies and in-Situ wh-Questions as Test Cases on How to Approach Experimental Linguistics Research That Pursues Theoretical Linguistics Questions.Leticia Pablos, Jenny Doetjes & Lisa L.-S. Cheng - 2018 - Frontiers in Psychology 8:307606.
    The empirical study of language is a young field in contemporary linguistics. This being the case, and following a natural development process, the field is currently at a stage where different research methods and experimental approaches are being put into question in terms of their validity. Without pretending to provide an answer with respect to the best way to conduct linguistics related experimental research, in this article we aim at examining the process that researchers follow in the design and implementation (...)
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  19.  34
    Effects of Case and Transitivity on Processing Dependencies: Evidence From Niuean.Rebecca Tollan, Diane Massam & Daphna Heller - 2019 - Cognitive Science 43 (6):e12736.
    We investigate the processing of wh questions in Niuean, a VSO ergative–absolutive Polynesian language. We use visual‐world eye tracking to examine how preference for subject or object dependencies is affected (a) by case marking of the subject (ergative vs. absolutive) and object (absolutive vs. oblique), and (b) by the transitivity of the verb (whether the object is obligatory). We find that Niuean exhibits (a) an effect of case, whereby dependencies of arguments with absolutive case (whether subjects or objects) (...)
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  20.  47
    Rethinking historical distance: From doctrine to heuristic.Mark Salber Phillips - 2011 - History and Theory 50 (4):11-23.
    ABSTRACTIn common usage, historical distance refers to a position of detached observation made possible by the passage of time. Understood in these terms, distance has long been regarded as essential to modern historical practice, but this conception narrows the idea of distance and burdens it with a regulatory purpose. I argue that distance needs to be re‐conceived in terms of the wider set of engagements that mediate our relations to the past, as well as the (...)
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  21.  32
    Non‐adjacent Dependencies Processing in Human and Non‐human Primates.Raphaëlle Malassis, Arnaud Rey & Joël Fagot - 2018 - Cognitive Science 42 (5):1677-1699.
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  22.  38
    Semantically Restricted Argument Dependencies.Alastair Butler - 2011 - Journal of Logic, Language and Information 20 (1):69-114.
    This paper presents a new take on how argument dependencies in natural language are established and constrained. The paper starts with a rather standard view that (quantificational) argument dependencies are operator-variable dependencies. The interesting twist the paper offers is to eliminate the need for syntax that serves to enforce what the operator-variable dependencies are. Instead the role of ensuring grammatical and generally unambiguous forms is taken up by semantics imposing what are dependency requirements for any interpretation (...)
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  23.  18
    Locality and the architecture of syntactic dependencies.Luis López - 2007 - New York: Palgrave Macmillian.
    A study on minimalist syntax develops an empirical argument for a crash-proof computational system. A crash-proof system is obtained if syntactic dependencies are strictly local (i.e. there is no long-distance Agree). Apparent long-distance dependencies turn out to be the outcome of a recursive chain on local complex dependencies. This framework allows for novel analyses of quirky subjects in Icelandic and Spanish, indefinite SE in Spanish and different types of expletive constructions in English, French, (...)
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  24.  40
    An Effective Two-Stage Model for Exploiting Non-Local Dependencies in Named Entity Recognition.Christopher D. Manning - unknown
    This paper shows that a simple two-stage approach to handle non-local dependencies in Named Entity Recognition (NER) can outperform existing approaches that handle non-local dependencies, while being much more computationally efficient. NER systems typically use sequence models for tractable inference, but this makes them unable to capture the long distance structure present in text. We use a Conbel.
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  25.  99
    The experience dependent dynamics of human consciousness.Birgitta Dresp-Langley - 2018 - Open Journal of Philosophy 8 (2):116-143.
    By reviewing most of the neurobiology of consciousness, this article highlights some major reasons why a successful emulation of the dynamics of human consciousness by artificial intelligence is unlikely. The analysis provided leads to conclude that human consciousness is epigenetically determined and experience and context-dependent at the individual level. It is subject to changes in time that are essentially unpredictable. If cracking the code to human consciousness were possible, the result would most likely have to consist of a temporal pattern (...)
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  26.  83
    From Prolepsis to Hyperraising.Magdalena Lohninger, Iva Kovač & Susanne Wurmbrand - 2022 - Philosophies 7 (2):32.
    Case, agreement, and A-movement dependencies across finite clause boundaries, such as Hyperraising or Long-Distance Case or Agreement [LDA], are available in many typologically diverse languages. The research on such dependencies typically distinguishes between cross-linguistically restricted true A-dependencies across finite clauses, and generally available binding-like A′-dependencies as found in Prolepsis. In this paper, we investigate both types of configurations in parallel and refer to this as the A-domain. Since the diagnostics to distinguish A-configurations vary across (...)
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  27. Sequential Expectations: The Role of Prediction‐Based Learning in Language.Jennifer B. Misyak, Morten H. Christiansen & J. Bruce Tomblin - 2010 - Topics in Cognitive Science 2 (1):138-153.
    Prediction‐based processes appear to play an important role in language. Few studies, however, have sought to test the relationship within individuals between prediction learning and natural language processing. This paper builds upon existing statistical learning work using a novel paradigm for studying the on‐line learning of predictive dependencies. Within this paradigm, a new “prediction task” is introduced that provides a sensitive index of individual differences for developing probabilistic sequential expectations. Across three interrelated experiments, the prediction task and results thereof (...)
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  28. Paradoxes of aesthetic distance.Oswald Hanfling - 2003 - British Journal of Aesthetics 43 (2):175-186.
    A feature that contributes to the charm of much poetry is its obscurity and indirectness. We want to grasp what the poet is saying and yet, it appears, to do so only with difficulty. How is this preference to be explained? (1) It contributes to promoting an ‘aesthetic attitude’. (2) It conforms to certain general features of human psychology, including (a) a general preference for indirectness and indeterminacy and (b) the pleasure of working things out. Distance, in the relevant (...)
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  29.  35
    Consequences of the Serial Nature of Linguistic Input for Sentenial Complexity.Daniel Grodner & Edward Gibson - 2005 - Cognitive Science 29 (2):261-290.
    All other things being equal the parser favors attaching an ambiguous modifier to the most recent possible site. A plausible explanation is that locality preferences such as this arise in the service of minimizing memory costs—more distant sentential material is more difficult to reactivate than more recent material. Note that processing any sentence requires linking each new lexical item with material in the current parse. This often involves the construction of longdistance dependencies. Under a resource‐limited view of (...)
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  30.  46
    (1 other version)On the expressivity of feature logics with negation, functional uncertainty, and sort equations.Franz Baader, Hans-Jürgen Bürckert, Bernhard Nebel, Werner Nutt & Gert Smolka - 1993 - Journal of Logic, Language and Information 2 (1):1-18.
    Feature logics are the logical basis for so-called unification grammars studied in computational linguistics. We investigate the expressivity of feature terms with negation and the functional uncertainty construct needed for the description of long-distance dependencies and obtain the following results: satisfiability of feature terms is undecidable, sort equations can be internalized, consistency of sort equations is decidable if there is at least one atom, and consistency of sort equations is undecidable if there is no atom.
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  31.  38
    Island constraints and overgeneralization in language acquisition.Ben Ambridge - 2015 - Cognitive Linguistics 26 (2):361-370.
    Name der Zeitschrift: Cognitive Linguistics Jahrgang: 26 Heft: 2 Seiten: 361-370.
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  32.  15
    The N400 is Elicited by Meaning Changes but not Synonym Substitutions: Evidence From Persian Phrasal Verbs.Kate Stone, Naghmeh Khaleghi & Milena Rabovsky - 2023 - Cognitive Science 47 (12):e13394.
    We tested two accounts of the cognitive process underlying the N400 event‐related potential component: one that it reflects meaning‐based processing and one that it reflects the processing of specific words. The experimental design utilized separable Persian phrasal verbs, which form a strongly probabilistic, longdistance dependency, ideal for the study of probabilistic processing. In sentences strongly constraining for a particular continuation, we show evidence that between two low‐probability words, only the word that changed the expected meaning of the sentence (...)
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  33.  38
    Enhancing legal judgment summarization with integrated semantic and structural information.Jingpei Dan, Weixuan Hu & Yuming Wang - forthcoming - Artificial Intelligence and Law:1-22.
    Legal Judgment Summarization (LJS) can highly summarize legal judgment documents, improving judicial work efficiency in case retrieval and other occasions. Legal judgment documents are usually lengthy; however, most existing LJS methods are directly based on general text summarization models, which cannot handle long texts effectively. Additionally, due to the complex structural characteristics of legal judgment documents, some information may be lost by applying only one single kind of summarization model. To address these issues, we propose an integrated summarization method (...)
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  34.  18
    A usage-based account of subextraction effects.Rui P. Chaves & Adriana King - 2019 - Cognitive Linguistics 30 (4):719-750.
    The idea that conventionalized general knowledge – sometimes referred to as a frame – guides the perception and interpretation of the world around us has long permeated various branches of cognitive science, including psychology, linguistics, and artificial intelligence. In this paper we provide experimental evidence suggesting that frames also play a role in explaining certain long-distance dependency phenomena, as originally proposed by Deane (1991). We focus on a constraint that restricts the extraction of an NP from another (...)
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  35.  45
    A Principled Approach to Feature Selection in Models of Sentence Processing.Garrett Smith & Shravan Vasishth - 2020 - Cognitive Science 44 (12):e12918.
    Among theories of human language comprehension, cue‐based memory retrieval has proven to be a useful framework for understanding when and how processing difficulty arises in the resolution of longdistance dependencies. Most previous work in this area has assumed that very general retrieval cues like [+subject] or [+singular] do the work of identifying (and sometimes misidentifying) a retrieval target in order to establish a dependency between words. However, recent work suggests that general, handpicked retrieval cues like these may (...)
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  36.  55
    Language as a phenomenon of the third kind.Ewa Dąbrowska - 2020 - Cognitive Linguistics 31 (2):213-229.
    While many linguists view language as either a cognitive or a social phenomenon, it is clearly both: a language can live only in individual minds, but it is learned from examples of utterances produced by speakers engaged in communicative interaction. In other words, language is what (Keller 1994. On language change: The invisible hand in language. London: Taylor & Francis) calls a “phenomenon of the third kind”, emerging from the interaction of a micro-level and a macro-level. Such a dual perspective (...)
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  37.  51
    Incorporating Non-local Information into Information Extraction Systems by Gibbs Sampling.Christopher Manning - unknown
    Most current statistical natural language processing models use only local features so as to permit dynamic programming in inference, but this makes them unable to fully account for the long distance structure that is prevalent in language use. We show how to solve this dilemma with Gibbs sam- pling, a simple Monte Carlo method used to perform approximate inference in factored probabilistic models. By using simulated annealing in place of Viterbi decoding in sequence models such as HMMs, CMMs, (...)
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  38.  50
    Difference and Dependency, Violence and Sublimation.Leonard Lawlor - 2018 - Philosophy Today 62 (2):607-617.
    This essay assesses Kelly Oliver’s long publication career by focusing on two novel ideas we find in her work. Both are ideas belonging to the new kind of ethics Oliver envisions. On the one hand, there is the idea of dependency. Through dependency, she aims to ground an obligation to care for the ones who provide the care to the dependents. The second idea is sublimation. Through her studies of psychoanalysis, Oliver shows that sublimation allows the subject to (...) herself from the violence of the drives. Sublimation is Oliver’s response to constitutive violence. In regard to Oliver’s ethical vision, I raise two questions. The first concerns the kind of obligation Oliver grounds; it seems to be hypothetical and not categorical. The second question concerns constitutive violence, whose existence Oliver seems to argue against. I conclude my essay by arguing that we must recognize the constitutive violence in all experience, and find a response to it. (shrink)
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  39.  38
    On the status of certain island violations in korean.Younghee Na & G. J. Huck - 1993 - Linguistics and Philosophy 16 (2):181 - 229.
    We have demonstrated in this study that the island phenomena exhibited in Korean complex constructions, such as they are, follow from the strict application of the Argument Condition to the semantic interpretations of those constructions — and not from formal restrictions on the location of the antecedents of gaps. The AC was shown to entail a kind of subjaceny restriction, although it is immaterial to the AC whether a particular gap is locally bound in a clause as long as (...)
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  40.  7
    Linguagem e Meditação: Considerações de Um Corredor de Longas Distâncias.César Fernando Meurer Meurer - 2018 - Simbio-Logias Revista Eletrônica de Educação Filosofia e Nutrição 10 (13):55-67.
    Can a lonely long-distance run instantiate a meditation? Based on personal experience with running, I develop an affirmative answer to this question. First, I distinguish contemplation from meditation, proposing that the former is a non-reflexive activity focused on the monitoring of one’s own body, and that the latter is a reflexive activity that includes a “self” in memories of episodes from the personal past as well as in episodic counterfactual thoughts and in episodic future thinking. Next, I suggest (...)
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  41.  24
    On Empirical Methodology, Constraints, and Hierarchy in Artificial Grammar Learning.Willem J. M. Levelt - 2020 - Topics in Cognitive Science 12 (3):942-956.
    Levelt, reviewing the AGL field from a psycholinguistic perspective, identifies various gaps and makes a number of concrete suggestions for improving several currently used experimental designs. He raises the question whether artificial (and natural) grammar learning is about detecting ‘rules’, as is commonly assumed, or rather the detection of a set of ‘constraints’. He cautions the community to not ignore ‘semantics’, and recommends to consider less artificial tasks, that may be needed for learning more complex rules by human or nonhuman (...)
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  42.  24
    Artificial Grammar Learning Capabilities in an Abstract Visual Task Match Requirements for Linguistic Syntax.Gesche Westphal-Fitch, Beatrice Giustolisi, Carlo Cecchetto, Jordan S. Martin & W. Tecumseh Fitch - 2018 - Frontiers in Psychology 9:387357.
    Whether pattern-parsing mechanisms are specific to language or apply across multiple cognitive domains remains unresolved. Formal language theory provides a mathematical framework for classifying pattern-generating rule sets (or “grammars”) according to complexity. This framework applies to patterns at any level of complexity, stretching from simple sequences, to highly complex tree-like or net-like structures, to any Turing-computable set of strings. Here, we explored human pattern-processing capabilities in the visual domain by generating abstract visual sequences made up of abstract tiles differing in (...)
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  43.  9
    Long Term Follow-Up on Pediatric Cases With Congenital Myasthenic Syndromes—A Retrospective Single Centre Cohort Study.Adela Della Marina, Eva Wibbeler, Angela Abicht, Heike Kölbel, Hanns Lochmüller, Andreas Roos & Ulrike Schara - 2020 - Frontiers in Human Neuroscience 14.
    Introduction: Congenital myasthenic syndromes refer to a heterogenic group of neuromuscular transmission disorders. CMS-subtypes are diverse regarding exercise intolerance and muscular weakness, varying from mild symptoms to life-limiting forms with neonatal onset. Long-term follow-up studies on disease progression and treatment-response in pediatric patients are rare.Patients and Methods: We analyzed retrospective clinical and medication data in a cohort of 32 CMS-patients including the application of a standardized, not yet validated test to examine muscular strength and endurance in 21 patients at (...)
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  44.  21
    Sentence Processing and Syntactic Theory.Dave Kush & Brian Dillon - 2021 - In Nicholas Allott, Terje Lohndal & Georges Rey (eds.), A Companion to Chomsky. Wiley. pp. 305–324.
    In the 1950s, Noam Chomsky offered a new vision for linguistic research and syntacticians. This chapter explores some ways in which Chomsky's linguistic work has influenced research on one domain of linguistic performance, sentence processing, over the last half century. It shows that Chomsky's claim in Aspects of the Theory of Syntax is largely borne out: "the study of performance will proceed only as far as the study of the underlying competence permits". The chapter briefly addresses a question about the (...)
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  45.  32
    Semiotic Tools For Multilevel Cell Communication.Franco Giorgi & Gennaro Auletta - 2016 - Biosemiotics 9 (3):365-382.
    Cell communication plays a key role in multicellular organisms. In developing embryos as in adult organisms, cells communicate by coordinating their differentiation through the establishment and/or renewal of a variety of cell communication channels. Under both these conditions, cells interact by either receptor signalling, surface recognition of specific cell adhesion molecules or transfer of cytoplasmic components through junctional coupling. In recent years, it has become apparent that cells may also communicate through the extracellular release of microvesicles. They may originate as (...)
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  46.  52
    Clausal Pied-Piping.Karlos Arregi - 2003 - Natural Language Semantics 11 (2):115-143.
    In Basque, wh-movement can pied-pipe an entire clause. The surface syntax of clausal pied-piping structures suggests that their syntax and semantics should be similar to scope marking constructions as analyzed in the Indirect Dependency approach. However, data having to do with presupposition projection and the interpretation of how many-questions show that clausal pied-piping structures are actually more similar to their long-distance wh-movement counterparts than to scope marking constructions. I develop an analysis which takes into account these facts. Specifically, (...)
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  47.  35
    The Christianization of Usury in Early Modern Europe.Mark Valeri - 2011 - Interpretation: A Journal of Bible and Theology 65 (2):142-152.
    In the early seventeenth century, the beginning of Europe's commercial revolution forced reconsiderations of the use of credit in long-distance trade. Unlike their Catholic competitors, Protestant regimes depended on the exchange of paper securities and other credit instruments. Protestant moralists developed rationalizations for usury as a concerted effort to protect the Protestant interest in the context of imperial warfare and colonial settlement. By the end of the seventeenth century, these moralists had made modern, market-oriented conceptions of usury commonplace (...)
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  48.  32
    Intrinsic neuronal determinants that promotes axonal sprouting and elongation.Pico Caroni - 1997 - Bioessays 19 (9):767-775.
    Nerve processes elongate, branch and form synaptic contacts in a highly regulated and specific manner. Longdistance axon elongation is restricted to the main phase of axon formation during development, but can be reinduced upon lesions in the adult (regeneration). It correlates with the expression of defined genes, including proteins involved in signalling (e.g. src, NCAM, integrins), transcription factors (e.g. c‐jun) and structural proteins (e.g. actin and tubulin isoforms). Activation of an axon elongation program may require bcl‐2. The formation (...)
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  49.  25
    What are the functions of kinesin?Michael P. Sheetz - 1987 - Bioessays 7 (4):165-168.
    A variety of intracellular motile processes involve the directed movement of particles along microtubules, including organelle transport, endoplasmic reticulum extension, and movements in mitosis. Recently, a microtubule‐dependent motor protein, kinesin, was purified and was found to be present in a soluble form in a wide variety of organisms and tissues. Because microtubules provide polar pathways over long distances within cells, kinesin and the motors which move in the opposite direction to kinesin on microtubules provide a mechanism for directed communications (...)
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  50.  37
    Longdistance signal transfer in transcriptionally active chromatin – how does it occur?Andrey N. Luchnik - 1985 - Bioessays 3 (6):249-252.
    Gene transcription in eukaryotes is associated with conformational changes of a large area of chromatin adjacent to a gene. This rearrangement may involve the whole loop (topological domain) to which a given gene belongs.Regulatory events associated with activation or inactivation of transcription are found to act through relatively short nucleotide sequences, often located several thousand base pairs apart from gene. These sequences, termed enhancers may act independently on their distance from or orientation with respect to the gene.Both long‐range (...)
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