Ethical approval must be obtained before medical research can start. We describe the differences in EA for an pseudonymous, non-interventional, observational European study. Sixteen European national coordinators of the international study on very old intensive care patients answered an online questionnaire concerning their experience getting EA. N = 8/16 of the NCs could apply at one single national ethical committee, while the others had to apply to various regional ECs and/or individual hospital institutional research boards. The time between applying for (...) EA and the first decision varied between 7 days and 300 days. In 9/16 informed consent from the patient was not deemed necessary; in 7/16 informed consent was required from the patient or relatives. The upload of coded data to a central database required additional information in 14/16. In 4/16 the NCs had to ask separate approval to keep a subject identification code list to de-pseudonymize the patients if questions would occur. Only 2/16 of the NCs agreed that informed consent was necessary for this observational study. Overall, 6/16 of the NCs were satisfied with the entire process and 8/16 were unsatisfied. 11/16 would welcome a European central EC that would judge observational studies for all European countries. Variations in the process and prolonged time needed to get EA for observational studies hampers inclusion of patients in some European countries. This might have a negative influence on the external validity. Further harmonization of ethical approval process across Europe is welcomed for low-risk observational studies. Getting ethical approval for low-risk, non-interventional, observational studies varies enormously across European countries. (shrink)

This paper aims to argue for the thesis that it is not a priori morally justified that the first phase of space colonisation is based on sexual reproduction. We ground this position on the argument that, at least in the first colonisation settlements, those born in space may not have a good chance of having a good life. This problem does not depend on the fact that life on another planet would have to deal with issues such as solar radiation (...) or with the decrease or entire absence of the force of gravity. These issues could plausibly be addressed given that the planets or settlements we will feasibly colonise could be completely transformed through geoengineering processes. Likewise, the ability of humans to live in space could be enhanced through genetic modification interventions. Even if, however, the problems concerning survival in space were solved, we think that, at least in the first period of colonisation of space or other planets, giving birth to children in space could be a morally irresponsible choice since we argue, the life we ​​could give them might not be good enough. We contend that this is the case since when we decide to have a baby. We argue that it is not morally right to be content that our children have a minimally sufficient life worth living; before we give birth to children in space, we should make sure we can give them a reasonable chance of having a good life. This principle applies both on Earth - at least where you can choose - and for space travel. (shrink)

In ancient Chinese culture, landscape constituted a fundamental element in religious, literary and artistic expressions. This contribution is intended as an imperfect and concise attempt to trace the “guidelines” – influenced above all by Daoist doctrine – of Chinese thought on landscape within the literature and pictorial art of traditional China.

The translation of this work has been funded by SEPS - Segretariato Europeo per le Pubblicazioni Scientifiche.

Maurizio Ferraris explores how, through the reading of Proust's _In Search of Lost Time_, one can explore memory, art, and society, using the book as a guide for living life.

This article sets the stage for a genealogy of the postgenomic body. It starts with the current transformative views of epigenetics and microbiomics to offer a more pluralistic history in which the ethical problem of how to live with a permeable body – that is plasticity as a form of life – is pervasive in traditions pre-dating and coexisting with modern biomedicine (particularly humoralism in its several ramifications). To challenge universalizing narratives, I draw on genealogical method to illuminate the unequal (...) distribution of plasticity across gender and ethnic groups. Finally, after analysing postgenomics as a different thought-style to genomics, I outline some of its implications for notions of plasticity. I argue that postgenomic plasticity is neither a modernistic plasticity of instrumental control of the body nor a postmodernist celebration of endless potentialities. It is instead closer to an alter-modernistic view that disrupts clear boundaries between openness and determination, individual and community. (shrink)

v. 1. Il movimento neoscolastico e la fondazione della Rivista -- v. 2. La riflessione filosofica dalle pagine della Rivista.

An analysis of how capitalism today produces subjectivity like any other “good,” and what would allow us to escape its hold. “Capital is a semiotic operator”: this assertion by Félix Guattari is at the heart of Maurizio Lazzarato's Signs and Machines, which asks us to leave behind the logocentrism that still informs so many critical theories. Lazzarato calls instead for a new theory capable of explaining how signs function in the economy, in power apparatuses, and in the production of (...) subjectivity. Moving beyond the dualism of signifier and signified, Signs and Machines shows how signs act as “sign-operators” that enter directly into material flows and into the functioning of machines. Money, the stock market, price differentials, algorithms, and scientific equations and formulas constitute semiotic “motors” that make capitalism's social and technical machines run, bypassing representation and consciousness to produce social subjections and semiotic enslavements. Lazzarato contrasts Deleuze and Guattari's complex semiotics with the political theories of Jacques Rancière, Antonio Negri and Michael Hardt, Paolo Virno, and Judith Butler, for whom language and the public space it opens still play a fundamental role. Lazzarato asks: What are the conditions necessary for political and existential rupture at a time when the production of subjectivity represents the primary and perhaps most important work of capitalism? What are the specific tools required to undo the industrial mass production of subjectivity undertaken by business and the state? What types of organization must we construct for a process of subjectivation that would allow us to escape the hold of social subjection and machinic enslavement? In addressing these questions, Signs and Machines takes on a task that is today more urgent than ever. (shrink)

Nationalism and patriotism are two of the most powerful forces shaping world history. In this paperback edition of a highly successful, wide-ranging study, Maurizio Viroli shows exactly why patriotism is a political virtue and nationalism a political vice.

The article Thinking embodiment with genetics: epigenetics and postgenomic biology in embodied cognition and enactivism, written by Maurizio Meloni and Jack Reynolds, was originally published electronically on the publisher’s internet portal on 18 June 2020 without open access. With the author’ decision to opt for Open Choice the copyright of the article changed on 6 November 2020 to ©The Author 2020 and the article is forthwith distributed under a Creative Commons Attribution.

As space travel and intentions to colonise other planets are becoming the norm in public debate and scholarship, we must also confront the technical and survival challenges that emerge from these hostile environments. This paper aims to evaluate the various arguments proposed to meet the challenges of human space travel and extraterrestrial planetary colonisation. In particular, two primary solutions have been present in the literature as the most straightforward solutions to the rigours of extraterrestrial survival and flourishing: (1) geoengineering, where (...) the environment is modified to become hospitable to its inhabitants, and (2) human (bio)enhancement where the genetic heritage of humans is modified to make them more resilient to the difficulties they may encounter as well as to permit them to thrive in non-terrestrial environments. Both positions have strong arguments supporting them but also severe philosophical and practical drawbacks when exposed to different circumstances. This paper aims to show that a principled stance where one position is accepted wholesale necessarily comes at the opportunity cost of the other where the other might be better suited, practically and morally. This paper concludes that case-by-case evaluations of the solutions to space travel and extraterrestrial colonisation are necessary to ensure moral congruency and the survival and flourishing of astronauts now and into the future. (shrink)

In this book, Esposito presents a historiography of organicist and holistic thought through an examination of the work of leading biologists from Britain and America. He shows how this work relates to earlier Romantic tradition and sets it within the wider context of the history and philosophy of the life sciences.

Hamlet swears by his father that he will be revenged, and in this scene we have the characteristics of the social object oath: it is a word that is said and not simply thought of; it is a given word that cannot be withdrawn without braking the oath; it is a written word, which has a value insofar as is fixed in the memories; and it is a loyal word, since an oath presupposes faithfulness.

italiano: Secondo l’interpretazione di Hegel gli edifici religiosi egiziani, e tra essi in particolare i templi, rappresentano l’inizio della storia dell’architettura, e con ciò di tutta la storia dell’arte.L’architettura religiosa egiziana ha un carattere simbolico, perché la sua forma cerca di rappresentare il contenuto spirituale senza esservi pienamente adeguata. Così il tempio egizio allude al divino con la sua intera struttura, ma non ha propriamente un interno, dedicato al culto dell’immagine del dio.L’egittologia contemporanea ha corretto Hegel su questo punto, perché (...) in generale il tempio egizio aveva un interno che custodiva l’immagine della divinità. Tuttavia la tesi di Hegel rimane paradossalmente valida per un caso particolare dell’esperienza egiziana, che egli non poteva conoscere: nella religione monoteista di Amarna il tempio del dio solare Aton non ha immagini e non ha un centro, perché il divino è presente dappertutto, come la luce del sole, che illumina egualmente ogni parte del tempio..Parole chiave: Egitto; architettura; tempio; simbolo; immagine. (shrink)

The essay maintains that, despite the significant successive transformations, a ordoliberal moment operates within the neoliberal program. Ordoliberalism establishes a specific political anthropology based on the centrality of economic action and on an a-revolutionary temporality that enhances the normative continuity of the tradition. Even against the specific configurations that the State can assume, especially the democratic one, it also aims at the constant reactivation of a political as a fundamental decision in favor of the economic.

L'article s'attaque aux racines mêmes du « mystère platonicien » en partant du constat de son caractère proprement « inexplicable »: qu'un auteur, dont on possède l'ensemble de l'œuvre écrite autorise des lectures, non seulement diverses, ce qui est légitime, mais également contradictoires, n'a aucun sens. L'article indique brièvement les éléments qui expliquent cette situation paradoxale et met en valeur les contributions de l'École de Tübingen (Krämer, Gaiser), qui insistent sur les « auto-témoignages » de Platon et sur la tradition (...) indirecte en vue d'une compréhension tout à fait nouvelle de Platon. L'auteur tente ensuite de dissiper quelques-unes des équivoques les plus graves qui grèvent le débat qu'elles ont suscité. L'article expose les analyses de Reale, qui éclairent d'un jour nouveau la valeur paradigmatique de cette nouvelle position, et l'apport de Szlezák, qui produit l'analyse des techniques d'écriture employées par Platon. Les commentaires de Movia et de Migliori prouvent finalement la puissance herméneutique du « nouveau paradigme » et apportent une série d'approfondissements explicatifs, surtout au sujet de la dialectique. The article tackles the roots of the « Plato mystery », beginning with its « inexplicable » existence. It is a nonsensical that an author, whose written corpus we possess, is not only open to different valid interpretations, but even to contradictory ones. After pointing out the elements behind this paradoxical situation, the contributions of the Tübingen school (Krämer, Gaiser) that enhance Plato's own testimony and the indirect tradition in respect of a renewed Platonic comprehension, are underlined. The author then attempts to eliminate some of the major misunderstandings which blocked the previous debate. The article exposes Reale's analysis, who clarifies the paradigmatic value of the new proposal, and the Szlezák's contribution, who threats the analysis of the writing techniques of Plato. Finally Movia's and Migliori's commentaries verify the hermeneutical capabilities of the « new paradigma » and bring a set of thorough examination of the dialectic mainly. (shrink)

Sex robots are already a reality: in this provocative text, Maurizio Balistreri explores the fascinating world of future sex, exploring the ethical questions raised by the existence of a sex robot industry.

There is a growing body of scholarship that is addressing the ethics, in particular, the bioethics of space travel and colonisation. Naturally, a variety of perspectives concerning the ethical issues and moral permissibility of different technological strategies for confronting the rigours of space travel and colonisation have emerged in the debate. Approaches ranging from genetically enhancing human astronauts to modifying the environments of planets to make them hospitable have been proposed as methods. This paper takes a look at a critique (...) of human bioenhancement proposed by Mirko Garasic who argues that the bioenhancement of human astronauts is not only functional but necessary and thus morally permissible. However, he further claims that the bioethical arguments proposed for the context of space do not apply to the context of Earth. This paper forwards three arguments for how Garasic’s views are philosophically dubious: (1) when he examines our responsibility towards future generations he refers to a moral principle (which we will call the principle of mere survival) which, besides being vague, is not morally acceptable; (2) the idea that human bioenhancement is not natural is not only debatable but morally irrelevant; and (3) it is not true that the situations that may arise in space travel cannot occur on Earth. We conclude that not only is the (bio)enhancement of humans on Earth permissible but perhaps even necessary in certain circumstances. (shrink)

This Article calls into question the primary meaning of copyright law. It argues that copyright is not primarily a legal instrument, but rather a fundamental mode of human existence. The starting point of the analysis is Kant’s definition of a book as a "public address" and of author’s rights as ultimately being grounded in the furtherance and maintenance of truth. Building on Kant’s argument, the Article defines the copyright primary subject matter as the act of speaking publicly in one’s own (...) name, and the copyright sphere as the author-public coalescence that such act of speaking generates. This enables reaching a proper understanding of the scope of copyright and to characterizing its specificity as compared to its "fellow rights," patents and trademarks. (shrink)

A history of colonization inflicts psychological, physical, and structural disadvantages that endure across generations. For an increasing number of Indigenous Australians, environmental epigenetics offers an important explanatory framework that links the social past with the biological present, providing a culturally relevant way of understanding the various intergenerational effects of historical trauma. In this paper, we critically examine the strategic uptake of environmental epigenetics by Indigenous researchers and policy advocates. We focus on the relationship between epigenetic processes and Indigenous views of (...) Country and health—views that locate health not in individual bodies but within relational contexts of Indigenous ontologies that embody interconnected environments of kin/animals/matter/bodies across time and space. This drawing together of Indigenous experience and epigenetic knowledge has strengthened calls for action including state-supported calls for financial reparations. We examine the consequences of this reimagining of disease responsibility in the context of “strategic biological essentialism,” a distinct form of biopolitics that, in this case, incorporates environmental determinism. We conclude that the shaping of the right to protection from biosocial injury is potentially empowering but also has the capacity to conceal forms of governance through claimants’ identification as “damaged,” thus furthering State justification of biopolitical intervention in Indigenous lives. (shrink)

We propose a mentalistic and nativist view of human early mental and social life and of the ontogeny of mindreading. We define the mental state of sharedness as the primitive, one-sided capability to take one's own mental states as mutually known to an i nteractant. We argue that this capability is an innate feature of the human mind, which the child uses to make a subjective sense of the world and of her actions. We argue that the child takes all (...) of her mental states as shared with her caregivers. This a llows her to interact with her caregivers in a mentalistic way from the very beginning and provides the grounds on which the later maturation of mindreading will build. As the latter process occurs, the child begins to understand the mental world in terms of differences between the mental states of different agents; subjectively, this also corresponds to the birth of privateness. ? (shrink)