The purpose of this paper is to defend, contra Fodor and Piattelli-Palmarini (F&PP), that the theory of natural selection (NS) is a perfectly bona fide empirical unified explanatory theory. F&PP claim there is nothing non-truistic, counterfactual-supporting, of an “adaptive” character and common to different explanations of trait evolution. In his debate with Fodor, and in other works, Sober defends NS but claims that, compared with classical mechanics (CM) and other standard theories, NS is peculiar in that its explanatory models are (...) a priori (a trait shared with few other theories). We argue that NS provides perfectly bona fide adaptive explanations of phenotype evolution, unified by a common natural-selection guiding principle. First, we introduce the debate and reply to F&PP’s main argument against NS. Then, by reviewing different examples and analyzing Fisher’s model in detail, we show that NS explanations of phenotypic evolution share a General Natural Selection Principle. Third, by elaborating an analogy with CM, we argue against F&PP’s claim that such a principle would be a mere truism and thus explanatorily useless, and against Sober’s thesis that NS models/explanations have a priori components that are not present in CM and other common empirical theories. Irrespective of differences in other respects, the NS guiding principle has the same epistemic status as other guiding principles in other highly unified theories such as CM. We argue that only by pointing to the guiding principle-driven nature that it shares with CM and other highly unified theories, something no-one has done yet in this debate, one can definitively show that NS is not defective in F&PP’s sense: in the respects relevant to the debate, Natural Selection is as defective and as epistemically peculiar as Classical Mechanics and other never questioned theories. (shrink)

Substructural approaches to paradoxes have attracted much attention from the philosophical community in the last decade. In this paper we focus on two substructural logics, named ST and TS, along with two structural cousins, LP and K3. It is well known that LP and K3 are duals in the sense that an inference is valid in one logic just in case the contrapositive is valid in the other logic. As a consequence of this duality, theories based on either logic are (...) tightly connected since many of the arguments for and objections against one theory reappear in the other theory in dual form. The target of the paper is making explicit in exactly what way, if any, ST and TS are dual to one another. The connection will allow us to gain a more fine-grained understanding of these logics and of the theories based on them. In particular, we will obtain new insights on two questions concerning ST which are being intensively discussed in the current literature: whether ST preserves classical logic and whether it is LP in sheep’s clothing. Explaining in what way ST and TS are duals requires comparing these logics at a metainferential level. We provide to this end a uniform proof theory to decide on valid metainferences for each of the four logics. This proof procedure allows us to show in a very simple way how different properties of inferences (unsatisfiability, supersatisfiability and antivalidity) that behave in very different ways for each logic can be captured in terms of the validity of a metainference. (shrink)

The literature on mathematical explanation contains numerous examples of explanatory, and not so explanatory proofs. In this paper we report results of an empirical study aimed at investigating mathematicians’ notion of explanatoriness, and its relationship to accounts of mathematical explanation. Using a Comparative Judgement approach, we asked 38 mathematicians to assess the explanatory value of several proofs of the same proposition. We found an extremely high level of agreement among mathematicians, and some inconsistencies between their assessments and claims in the (...) literature regarding the explanatoriness of certain types of proofs. (shrink)

Recent experiments have shown that naive speakers find borderline contradictions involving vague predicates acceptable. In Cobreros et al. we proposed a pragmatic explanation of the acceptability of borderline contradictions, building on a three-valued semantics. In a reply, Alxatib et al. show, however, that the pragmatic account predicts the wrong interpretations for some examples involving disjunction, and propose as a remedy a semantic analysis instead, based on fuzzy logic. In this paper we provide an explicit global pragmatic interpretation rule, based on (...) a somewhat richer semantics, and show that with its help the problem can be overcome in pragmatics after all. Furthermore, we use this pragmatic interpretation rule to define a new consequence-relation and discuss some of its properties. (shrink)

Principles of procreative beneficence (PPBs) hold that parents have good reasons to select the child with the best life prospects. Sparrow (2010) claims that PPBs imply that we should select only female children, unlesswe attach normative significance to “normal” human capacities. We argue that this claim fails on both empirical and logical grounds. Empirically, Sparrow’s argument for greater female wellbeing rests on a selective reading of the evidence and the incorrect assumption that an advantage for females would persist even when (...) a serious gender imbalance is obtained. Logically, PPBs cite only pro tanto reasons and allow that the good of an individual child could be outweighed by other morally relevant considerations, such as those which take collectively suboptimal outcomes into account. There is thus no need to attach value to the “normal.”. (shrink)

Este artigo revisa a idéia de filosofia “medieval” and põe ênfase na variedade de significados daquela palavra. O autor crê que necessitamos de uma nova terminologia para aquele período da história do pensamento e sugere, por razões históricas, as expressões “United Age” e “Formation Age”. Em todo o artigo prevalece uma tentativa de compreender a natureza da atividade filosófica e da história da filosofia.

An inquiry into the current ways of knowing, their ramifications, and institutional and noninstitutional artistic practices that provide channels for education from below. Artistic Ecologies: New Compasses and Tools aims to both analyze and speculate about potentials of artistic ecologies, collective learning, and engaged pedagogies to engender new institutionalities. Going beyond tensions between individuals and institutions, Artistic Ecologies examines avenues for collective learning. If learning for life is emancipation—understood not just as a matter of power but of freedom—the essential question (...) that emerges is: What knowledge makes us free and how can institutions help produce it? In search of an answer, this publication’s textual and visual contributions explore sites and practices through which new institutionalities can emerge. Artistic Ecologies comprises essays analyzing current ways of knowing and their ramifications (Marina Garcés, Yayo Herrero and Pirate Care) and portraying alternative ways of forming knowledge through institutional and non-institutional artistic practices (DAAR—Decolonizing Architecture Art Research, Yael Davids, Max Jorge Hinderer Cruz, The Sensing Salon). Artistic contributions in various formats—poems, drawings, visual essays—by Luna Acosta, CAConrads, Eva Ďurovec, Teuta Gatolin, Margherita Isola, and Jammers illustrate heterodox channels for questioning the dominant forms of knowledge and educating from below. (shrink)

El autor de este artículo lee el Apologeticum de Tertuliano como un texto de transición ideológica entre los primeros escritos mesiánicos del cristianismo y la teología política del siglo IV, i.e. una obra que fusiona teología imperial y cristianismo. Dejando de lado las disputas teológicas con el judaísmo, Tertuliano propone una discusión frontal con los romanos sobre la relación del concepto de divinidad con el poder político y quiere mostrar que la teología y la ética de los cristianos son mucho (...) más apropiadas para una realidad como el Imperio romano que las que ha impuesto la tradición politeísta. En este razonamiento se destaca la correspondencia entre monoteísmo y monarquía universal. The author of this paper reads Apologeticum by Tertullian as a text of ideological transition between the early messianic Christian writings and political fourth century theology, i.e. a work that combines Imperial theology and Christianity. Leaving apart the theological disputes with Judaism, Tertullian proposes a frontal discussion with the Romans on the relationship of the concept of divinity with political power and wants to show that theology and Christian ethics are much more appropriate for a reality as Roman Empire which has imposed the polytheistic tradition. His argumentation stands out the reciprocation between monotheism and universal monarchy. (shrink)

Traducción al español del artículo de Marc Richir «Phénoménologie et poésie», publicado en Serta: Revista Iberorrománica de Poesía y Pensamiento Poético, n.º 4, 1999, pp. 407-420. El artículo propone articular (comparando y diferenciando) la reflexión fenomenológica sin conceptos, propia de la fenomenología (que convoca esencias fenomenológicas), y la reflexión estética sin conceptos, en que se basa la poesía (que convoca categorías como singularidad y acontecimiento). El lugar de la afectividad en ambos tipos de reflexiones es uno de los factores dirimentes. (...) Por último, el autor aborda la cuestión de lo sublime y del esquematismo de la fenomenalización, al margen de toda intriga pulsional y psicoanalítica. (shrink)

This article presents a reconstruction of the so-called classical, formal or Mendelian genetics, which is intended to be more complete and adequate than existing reconstructions. This reconstruction has been carried out with the instruments, duly modified and extended with respect to the case under consideration, of the structuralist conception of theories. The so-called Mendel’s Laws, as well as linkage genetics and gene mapping are formulated in a precise manner while the global structure of genetics is represented as a theory-net. These (...) results are of methodological, philosophical and didactical relevance. (shrink)

RESUMEN Una atribución de agencia mental es definida como el acto de asignar el inicio o autoría de un pensamiento en primera persona a un agente específico, esto, con el fin de generar grados suficientes de control sobre nuestra vida cognitiva. Si bien esta estrategia es fundamental para distinguir diferentes tipos de estados cognitivos - tales como deliberaciones, razonamientos, juicios, entre otros -, muchos autores han indicado que también es clave para entender experiencias cognitivas psicopatológicas en psicosis. Este artículo revisa (...) la forma en que la estructura subjetiva de los delirios de inserción de pensamiento puede ser utilizada como una estrategia para evaluar los méritos argumentativos de las teorías que intentan explicar la arquitectura y naturaleza de las atribuciones de agencia mental. Luego de evaluar algunos aspectos fundamentales de las dos teorías dominantes en la literatura actual, se sugiere que, a pesar de sus importantes aportes al desarrollo de la discusión, tales enfoques no poseen los recursos explicativos suficientes para lidiar con el desafío propuesto. ABSTRACT An attribution of mental agency is defined as the act of assigning the initiation or authorship of a first personal thought to a specific agent in order to generate sufficient degrees of control over our own cognitive life. Although this strategy is crucial to distinguish different types of cognitive states - such as deliberations, reasonings, judgements, among others -, a number of authors have suggested that it is also crucial to understand psychopathological cognitive experiences in psychosis. This paper explores the way in which the subjective structure of thought insertion can be used as a strategy to evaluate the merits of theories aiming at explaining the nature and architecture of attributions of mental agency. After examining some of the most fundamental aspects of the two dominant theories in current literature, I suggest that, despite the contributions made by such theories to the discussion, none of them is able to face the challenge in a plausible way. (shrink)

Castro-Gómez, Santiago. Revoluciones sin sujeto. Slavoj Žižek y la crítica del historicismo posmoderno. Ciudad de México: Akal, 2015. 400 pp.

PurposeAnomic feelings are predicted to play a moderating role in the relationship between organisational justice perceptions and the citizenship use of the organisation's internet access, or cybercivism. The purpose of this paper is to hypothesise that, just as AFs are supported in prior research as able to intensify the negative effects of organisational justice on cyberloafing, they will also intensify the positive effects of OJ on cybercivism.Design/methodology/approachData were collected from 270 of the 1,547 respondents at a public university.FindingsExcept in the (...) case of procedural justice, the results support that AF act as a moderator of the OJ‐cybercivism link because, among employees with comparatively less AF, the perceptions of the OJ under study had a stronger impact on cybercivism.Research limitations/implicationsTo generalise from a convenience sample of 17 per cent to the entire University is unfeasible, let alone the “public sector” as a whole for a whole culture/country. Therefore, the paper only aims to be an early exploration of actual phenomenon, and to provide new insights necessary to understand the impact of pervasive new media and information and communication technologies on individual behaviour in virtual work settings.Practical implicationsThe findings contribute to an improved understanding of the influence of OJ on cybercivism. As a moderator, anomia is supported in our sample as one of the key “controllers” of the OJ predictions on cybercivism and sets a new scenario in seeking electronic business effectiveness. By encouraging convincing values and equity in the workplace, organisational management seems be on the right path to create the proper context for cybercivism to occur.Originality/valueEmployee AFs are shown to be a moderator in the relationship between OJ and cybercivism. This is the first empirical test of this interaction. (shrink)

A 68-year-old patient who suffered from gastric cancer diagnosed 8 months earlier presented with multiple peritoneal and hepatic metastasis, despite several rounds of chemo- and radiotherapy. After admission to hospital, his general condition quickly became severely compromised. He was nearly emaciated, despite being on partial parenteral feeding. Four years earlier, due to a cardiac arrhythmia that was refractory to medication, the patient had a cardiac pacemaker implanted, regulated to go off at frequencies of below 70 beats per minute. Given the (...) patient's terminal situation, the team started developing some doubts about the pacemaker's effects during his dying process. The patient had mentioned his intention to donate his pacemaker after his death, but had not asked for its deactivation. The specialists were not sure about the effect of the pacemaker in unnecessarily prolonging the patient's final hour. Nevertheless, they opposed deactivation, which they considered ethically uncertain. The family, who had been initially for the deactivation, decided against it. The patient's condition was progressively deteriorating, as he was falling into a state of sopor and, later, into a coma. (shrink)

There is vast evidence that accounts for the association between entrepreneurial orientation and the probability of starting a business. However, there are not many studies that test how psychological factors moderate this relationship. A variable that has been little studied in this relationship is Grit. Grit is considered a personality trait defined as perseverance and passion for long-term goals. Grit considers two sub-dimensions, one linked to the consistency of interests and the other linked to perseverance in the effort. The objective (...) of this article is to analyze the moderating role that both sub-dimensions of grit plays in the relationship between EO and PSB, considering its interaction with sociodemographic variables such as age, gender, and culture. This cross-sectional study has a sample of 1,761 participants, active workers. The EO scale and a Grit Scale were applied. In addition, participants were asked, based on their perception, how likely they were to start their own business within the next 5 years. A simple moderation analysis was considered to test the moderating role of grit in the relationship between EO and PSB. Subsequently, a double moderation analysis was carried out in order to identify which sociodemographic variables moderate the moderating effect of grit on the relationship in question. The results show that only the Grit-Passion component of grit moderates the relationship between EO and PSB. Regarding the sociodemographic variables, neither age, culture, nor gender showed a moderating effect on the moderation exercised by Grit-Passion in the relationship between OE and PSB. The results are discussed in terms of psychological capital, particularly with an emphasis on explaining why only the Grit-Passion shows a moderating effect on the relationship between EO and PSB, in detriment of Grit-Perseverance. In addition, the power of grit in the field of entrepreneurship is discussed, considering that its moderating effect is transversal to variations in age, gender and culture, as well as its relevance when considering interventions and pedagogical models in the field of entrepreneurship. (shrink)

El artículo aporta elementos fenomenológicos para reforzar algunas afirmaciones del enfoque simple en el contexto del debate sobre la identidad personal. Para esto se describe, en primer lugar, la propuesta de Geoffrey Madell y se introduce la noción fenomenológica del cuerpo propio (Leib). En segundo lugar, se muestra cómo la reducción vital propuesta por Francisco Leocata evita una posible interpretación inmanentista de la fenomenología, y favorece el desarrollo de una noción encarnada del yo y la posibilidad de entender el mundo (...) como traspasado por la subjetividad. Este desarrollo será el fundamento para mostrar, en tercer lugar, cómo la fenomenología de los vínculos personales y de la narración también pueden aportar a la cuestión de la identidad personal. (shrink)

Sobre el libro: Isaiah Berlin ha sido, además de un original e intuitivo historiador de las ideas y autor de numerosos conceptos teórico-políticos, un reconocido teorizador de la libertad y defensor acérrimo del pluralismo. Rasgos que lo han convertido en un innegable referente intelectual en nuestra época. Sobre el editor: El Editor de la presente obra, Pablo Badillo O'Farrell, con motivo del centenario del nacimiento de Berlin, ha reunido un número de contribuciones de estudiosos italianos y españoles que ofrecen, (...) desde muy diferentes perspectivas, un amplio abanico de miradas diversas sobre la obra y el pensamiento del autor, que van desde el análisis y confrontación del pluralismo valorativo y la ética de la libertad, al de la interculturalidad o la identidad personal y el nacionalismo, pasando por la confrontación de historicismo, historia de las ideas y contra-corriente. (shrink)

DNA methylation can be considered a component of epigenetic memory with a critical role during embryo development, and which undergoes dramatic reprogramming after fertilization. Though it has been a focus of research for many years, the reprogramming mechanism is still not fully understood. Recent results suggest that absence of maintenance at DNA replication is a major factor, and that there is an unexpected role for TET3-mediated oxidation of 5mC to 5hmC in guarding against de novo methylation. Base-resolution and genome-wide profiling (...) methods are enabling more comprehensive assessments of the extent to which ART might impair DNA methylation reprogramming, and which sequence elements are most vulnerable. Indeed, as we also review here, studies showing the effect of culture media, ovarian stimulation or embryo transfer on the methylation pattern of embryos emphasize the need to face ART-associated defects and search for strategies to mitigate adverse effects on the health of ART-derived children. DNA methylation, critical for embryo development, suffers significant changes after fertilization, including demethylation, remethylation and TET3-mediated oxidation of 5 mC to 5 hmC. In addition to infertility and environmental insults, ART could impact DNA methylation and ART related consequences in the offspring have been reported. (shrink)

Las diferencias entre Francisco Suárez y Juan de Mariana son notables, empezando por sus caracteres personales. En particular, en el tratamiento de una cuestión de tanta importancia en la teoría política de la época como el tema del derecho de resistencia y el tiranicidio, y pese a ciertos rasgos similares que los enemigos de los jesuitas se encar-garán de acentuar, un somero estudio puede revelar una serie de diferencias. No obstante, merece la pena examinar dichas diferencias tomando como referencia una (...) cuestión práctica que podría arrojar luz sobre el grado de profundidad de esas divergencias. En efecto, pese a las evidencias que demuestran que Mariana y Suárez se conocían, y a la dificultad de sostener la idea de que el segundo desconociese la obra de Mariana, el granadino no cita en ningún momento al talaverano al tratar el tema que concita nuestro interés. Más allá de la presencia evidente de cuestiones de estrategia política en dicho silencio, no cabe duda de que Suárez debía entender también que su teoría no coincidía con la de Marian. (shrink)

Which is the best icon of philosophical activity? The Spanish philosopher Garcia Morente analyses three sculptures: Le penseur by Rodin, Il pensieroso by Michelangelo and a sculpture known as El Doncel de Siguenza, in the cathedral of this Castilian town. Morente asserts that the latest reflects better than anyone else the nature of philosophy. In this paper the Morente’s view is rejected and another two ways of representing the philosophical activity are suggested: two ancient paintings that represent more properly the (...) philosophical labour, understood as an unending Socratic dialogue. (shrink)

This article analyzes the evolution of state capacity in Peru during the recent commodity boom. Peru’s economic growth happened in a context in which inclusive democratic institutions were at play for the longest period ever registered in the country and at a time when political elites decided to invest considerable resources in developing state capacity. This case illustrates how boom-led economic growth can lead to the institutional strengthening of a weak state. However, state capacity continues to be low in Peru. (...) The causal mechanism that yields such continuity differs from those entertained in classic path-dependent explanations of state capacity in Latin America. The article identifies a novel mechanism that helped reproduce the Peruvian path intertemporally. This relational mechanism suggests that state capacity remains low because of the relatively enhanced capacities of state challengers to locally fend off and contest an otherwise much stronger state apparatus. The article argues, on that basis, the need to employ a relational analysis that gauges net state strength with respect to the power acquired by relevant non-state actors who might challenge state authority across different local arenas. Classic conceptualizations of state capacity are indeed relational, but conventional applications are predominantly unilateral and, thus, misleading. Unilateral notions of state capacity are those that focus on either state efforts and investments to assert state capacity or, alternatively, on the presence of challenges that curtail the levels of actually observed state capacity. (shrink)

Aproximación al pensamiento de Rodolfo Kusch -- Canto e identidad en el Martín Fierro según Carlos Astrada y Rodolfo Kusch -- Donde el barro se subleva -- La rehabilitación del saber seminal como camino hacia una mística popular -- Kusch y el impulso social de nuestra época -- La barbarización de la civilización, una grieta de antaño -- ¿De dónde pensarnos?

Derrida’s thought is a dynamic dimension, a movement beyond any attempt of conclusive definition. However, is there any possibility to grasp this task of endless destabilization? This paper brings up the proposal of reading Derrida’s work from the close but at the same time aporetical relation between place and space. In this sense, we question the common understanding of space as uniform and empty continuum where place would be just a ‘limit’, a perimeter. In order to do so, we will (...) pay attention to the particular Topology that ‘translation’ illustrates in Derrida’s work, just as the reality of the spectre and mourning, stating these two dimensions as examples of Derrida’s strategy. In this sense, through translation and mourning, we manage to make out that Derrida’s work, even though cannot be summarized in a single object or idea, it might be understood as the endless question about the place of and for deconstruction, that is, about place as deconstruction of space. Thus, Derrida’s Topology may constitute a new and radical way to read not only his own work, but to question ourselves. (shrink)

Se propone un examen crítico de la última obra de J.-L. Marion titulada, dedicada a la unión de alma y cuerpo, y cuya tesis principal es: los problemas que esta unión suscita confunden dos términos, cuerpo y mi cuerpo. Esta confusión lleva a que se apliquen al primero categorías propias del segundo. Se examinan las "paradojas ónticas" que mi cuerpo (la carne) inaugura (a); se despeja la tesis de dos interpretaciones de las meditaciones primera y sexta (b); se discute la (...) "excepción a la metafísica" instaurada por el conocimiento de mi cuerpo (c); se arriesga, siguiendo una indicación del autor, la apertura a una dimensión ética que exige examinar ya no la unión de cuerpo y alma, sino la unión por el amor a un semejante y a la comunidad de semejantes (d). -/- The article carries out a critical examination of J.-L. Marion's latest work, "Sur la pensée passive de Descartes", whose main thesis is that the problems posed by the union of body and soul confuse two terms: body and my body. This confusion leads to the application to the former of categories inherent to the latter. The paper examines the "ontic paradoxes" that my body (the flesh) gives rise to (a); it clarifies the thesis of two interpretations of the First and Sixth Meditations (b); it discusses the "exception to metaphysics" established by the knowledge of my body (c); and, following an indication by the author, it proposes an opening to the ethical dimension, which demands an examination of the union, through love, with a fellow human being and with the community of human beings, rather than of the union of body and soul (d). -/- Neste artigo, propõe-se um exame crítico da última obra de J.-L. Marion, intitulada "Sur la pensée passive de Descartes", dedicada à união de alma e corpo, e cuja tese principal é: os problemas que essa união suscita confundem dois termos, corpo e meu corpo. Essa confusão leva a que se apliquem ao primeiro categorias próprias do segundo. Examinam-se os "paradoxos ônticos" que meu corpo (a carne) inaugura; a tese de duas interpretações das medita ccedil;ões primeira e sexta é esclarecida; arrisca-se, seguindo uma indicação do autor, a abertura a uma dimensão ética que exige examinar já não a união de corpo e alma, mas sim a união pelo amor a um semelhante e à comunidade de semelhantes. (shrink)

This chapter describes and analyzes some trends in the design of truth commission mandates beyond their original fact-finding function. It establishes links between the expansion of truth commission mandates and two particular challenges truth commissions have encountered, namely the poor record of implementation of their recommendations and challenges relating to the selection of commissioners. It also discusses the relationship between the temporal scope of the truth commission and its mandate, including a list of the number of years many commissions were (...) given or took to attempt to carry out their mandate. The chapter argues for more stringent functional analysis in the design of truth commission mandates. (shrink)

The aim of Kant’s Sources in Translation is to retrieve the rich intellectual world that influenced Kant’s philosophical development. In its first stage, the series makes available the most important textbooks Kant used throughout his long teaching career. Many of these textbooks are in Latin or in German and remain inaccessible to Anglophone readers. Lacking this material, however, it is difficult to appreciate Kant’s originality and process of philosophical maturation, for readers are unable to understand what prompted Kant to introduce (...) a distinction, offer a qualification, attack a position, or develop a new thesis. This background is essential to understand the genesis of Kant’s thought. -/- This volume provides a translation of Georg Friedrich Meier’s Auszugaus der Vernunftlehre, the textbook that serves not only as the basis for Kant’s lectures on logic and related Reflexionen but is also crucial for studying the so-called Jäsche Logic of 1800, which is redacted from the marginal and interleave notes found in Kant’s personal copy of Meier’s book. Given the recent growth in scholarship on Kant’s logic, normative epistemology, and the psychology of belief, this volume makes a major contribution to contemporary debates in the field. (shrink)

Clinical ethics refers to an emerging field in clinical medicine that focuses on the process of ethical decision-making in a clinicalsetting. It has developed as a result of a growing awareness that modern medicine – characterized by technological progress, culturaldiversity and social challenges – is posing a range of new “ethical dilemmas” that medical science alone cannot solve. For thisreason, clinical ethics is often linked to “ethics consultation,” which consists of services provided by an individual ethicist, ethicsteam or committee to (...) address the ethical issues involved in a specific clinical case. Although clinical ethics developed in the beginningmainly as a methodological analysis to arrive at a justification for clinical ethical decisions, it quickly has become clear thatthe difficulty in clinical decision-making is only one aspect of wider ethical problems pertaining to the doctor-patient relationshipas a whole and, most likely, to the core value of the medical profession. The principles method is usually presented as the mostpopular methodological approach to an analysis of clinical cases. However, strong criticism of this model has been voiced, and otheralternative approaches are referred to, such as the casuistry model. Recently, significant contributions have been made by narrativemedicine and virtue ethics. According to these methodologies, sound anthropology and a good relationship with the sick person arekey elements required of any person engaged in medical practice who aims to be genuinely appropriate from an ethical perspective. DOI: 10.5294/pebi.2016.20.1.3. (shrink)

From the thirties "sinarquismo" became an important sociopolitic and socioideological strength in contrast with the Mexican posrevolutionary political system. This article makes an attempts to give and answer to some questions : what was the "sinarquismo" origin and development? Under what bases did it take root socially, politically and ideologically speaking?. How was "sinarquismo" linked to the global context of conservative, catholic and right-winger movements? And what was the story of the "sinarquista" movement in the middle occident of Mexico?

El objetivo de este artículo es situar contextualmente y explicar algunas de las bases de la acción y el discurso de la corriente de la Tradición Iberoamericana de los Derechos Humanos (TIDH). La llegada de los europeos a América fue abordada por la Escuela ibérica de la Paz desde las premisas de una tradición que esbozó una Modernidad católica diferente a la Modernidad hegemónica. La influencia de esas visiones permitió que el proyecto de la Monarquía hispánica en general, y para (...) el Nuevo Mundo en particular, contase con una importante dimensión ético-religiosa. Las contradicciones entre ese proyecto y la realidad de la acción de los españoles en las Indias Occidentales conformaron el marco que suscitó las denuncias y las realizaciones teórico-prácticas de los misioneros que, llegados al nuevo continente desde la Península ibérica, iniciaron la TIDH. El reconocimiento de la común dignidad humana será el fundamento para la construcción de un discurso que empleará los derechos humanos universales como instrumento de defensa de los pueblos amerindios y afroamericanos, llevando a su mejor desarrollo las ideas de la Escuela ibérica. (shrink)

La confrontación de Heidegger con el humanismo es bien conocida: es la forma de toda metafísica entendida desde la subjetividad. La tesis que se defiende en el ensayo es que hay otra forma de entender su relación con el humanismo desde un punto de vista espacial. Se establece una relación entre la concepción del espacio cotidiano y de lo «a la mano» en Ser y Tiempo, y la noción de colección en los primeros humanistas. De este modo se muestra que (...) el humanismo temprano no es un antecesor del subjetivismo cartesiano, y que, tal como lo proponen Gadamer o Grassi, representa una corriente que bebe de fuentes diferentes a la dominante en el pensamiento occidental. Heidegger, de un modo indirecto, apropia ese pensamiento para su proyecto de Ser y Tiempo. (shrink)

During replication, the topology of DNA changes continuously in response to well‐known activities of DNA helicases, polymerases, and topoisomerases. However, replisomes do not always progress at a constant speed and can slow‐down and even stall at precise sites. The way these changes in the rate of replisome progression affect DNA topology is not yet well understood. The interplay of DNA topology and replication in several cases where progression of replication forks reacts differently to changes in DNA topology ahead is discussed (...) here. It is proposed, there are at least two types of replication fork barriers: those that behave also as topological barriers and those that do not. Two‐Dimensional (2D) agarose gel electrophoresis is the method of choice to distinguish between these two different types of replication fork barriers. (shrink)