The involvement of developing countries in international clinical trials is necessary for the development of appropriate medicines for local populations. However, the absence of appropriate structures for ethical review represents a barrier for certain countries. Currently there is very little information available on existing structures dedicated to ethics in western and central Africa. This article briefly describes historical milestones in the development of networks dedicated to capacity building in ethical review in these regions and outlines the major conclusions of two (...) workshops on this issue, which were held in September and October 2002 in Libreville, Gabon, and Paris, France. The workshops were the culmination of collaboration between the African Malaria Network Trust (AMANET) and the Pan African Bioethics Initiative (PABIN). They produced an update on ethics organizations with regard to mission, function, activities, members, and contact people, in eight countries within the regions discussed. As a result of the commitment of mandated delegates, a further prominent outcome followed these workshops: the creation of national structures, where none existed before, dedicated to the ethical review of clinical trials. (shrink)

An English translation of Pierre Bayle's posthumous last book, Entretiens de Maxime et de Themiste (1707), in which Bayle defends his skeptical position on the problem of the evil. This book is often cited and attacked by G.W. Leibniz in his Theodicy (1710). Over one hundred pages of original philosophical and historical material introduce the translation, providing it with context and establishing the work's importance.

Letter to du Faur de Pibrac, 1621.--Exercises against the Aristotelians, 1624.--Letter to Diodati, 1634.--De motu, 1642.--The rebuttals against Descartes, 1644.--The syntagma, 1658.

This classic work in the philosophy of physical science is an incisive and readable account of the scientific method. Pierre Duhem was one of the great figures in French science, a devoted teacher, and a distinguished scholar of the history and philosophy of science. This book represents his most mature thought on a wide range of topics.

Pierre Soulages : régulièrement j’élimine des toiles, inabouties ou qui ont “tourné mal ”, banales, sans rien qui m’excite et qui sont d’ailleurs des sortes d’aventures avortées… Alors qu’à un moment, il y avait quelque chose qui était apparu, qui me paraissait intéressant à pousser, à intensifier, et puis ça s’est détourné, ça s’est terminé par quelque chose de morne, pas vraiment inachevé parce que l’inachevé c’est par rapport à un modèle parfait ou… qui n’est pas du tout ce (...) que je poursuiv... (shrink)

The French philosopher and intellectual historian Pierre Hadot (1922-2010) is known primarily for his conception of philosophy as spiritual exercise, which was an essential reference for the later Foucault. An aspect of his work that has received less attention is a set of methodological reflections on intellectual history and on the relationship between philosophy and history. Hadot was trained initially as a philosopher and was interested in existentialism as well as in the convergence between philosophy and poetry. Yet he (...) chose to become a historian of philosophy and produced extensive philological work on neo-Platonism and ancient philosophy in general. He found a philosophical rationale for this shift in his encounter with Wittgenstein's philosophy in the mid-1950s (Hadot was one of Wittgenstein's earliest French readers and interpreters). For Hadot, ancient philosophy must be understood as a series of language games, and each language game must be situated within the concrete conditions in which it happened. The reference to Wittgenstein therefore supports a strongly contextualist and historicist stance. It also supports its exact opposite: presentist appropriations of ancient texts are entirely legitimate, and they are the only way ancient philosophy can be existentially meaningful to us. Hadot addresses the contradiction by embracing it fully and claiming that his own practice aims at a coincidence of opposites (a concept borrowed from the Heraclitean tradition). For Hadot the fullest and truest way of doing philosophy is to be a philosopher and a historian at the same time. (shrink)

Ni religion ni philosophie, l'animisme est une compréhension neuve de la nature et sans doute aussi un art de vivre qui, face à un monde agité, nous apprend à mieux habiter le monde. Et si l'animisme s'avérait la seule possibilité de sauver l'homme? Par une nouvelle façon d'être au monde, cette pensée, souvent méconnue, se donne à vivre comme une contre-philosophie. Cette initiation est un éveil de l'être tout entier, une nouvelle cosmogonie qui se donne à lire. Il s'agit de (...) réapprivoiser son corps en réapprenant, par exemple, à respirer, à contempler, à se dessaisir du sens des choses, à apprendre à oublier le temps. Face à un monde agité et au seuil du chaos, l'animisme invite à retrouver l'aspect essentiel des choses. Instaurant un dialogue entre la philosophie occidentale et cette philosophie africaine, Gaston-Paul Effa décentre la perspective, et change de focale : et si une nouvelle révolution était en marche? Et si, contrairement à l'idée reçue, c'était la Nature qui humanisait l'Homme? (shrink)

Journal Name: Semiotica Issue: Ahead of print.

L'actualite du kantisme n'est plus a demontrer. Que l'on songe a l'ethique de la discussion, a la theorie de la justice, a la philosophie des relations internationales, au probleme des arguments dits transcendantaux ou encore a la theorie de l'experience esthetique, la pensee de Kant temoigne aujourd'hui d'une incontestable vigueur et d'une etonnante jeunesse. Cette contemporaneite de Kant se traduit par de multiples tentatives de dialogue avec cette oeuvre afin d'en degager la pertinence pour le debat actuel. L'oeuvre de (...) class='Hi'>Pierre Laberge a su repondre de maniere exemplaire a ses ordres de preoccupations dans l'etude de Kant. Les auteurs sollicites ont eu l'occasion de collaborer avec Pierre Laberge et lui rendent ici un hommage posthume. Ce recueil reflete ainsi cette double exigence d'actualiser le kantisme et d'en analyser les textes. (shrink)

Over the last four decades, the French sociologist Pierre Bourdieu produced one of the most imaginative and subtle bodies of social theory of the postwar era. When he died two years ago, he was considered to be a thinker on a par with Foucault, Barthes, and Lacan--a public intellectual as influential to his generation as Sartre was to his. Science of Science and Reflexivity will be welcomed as a companion volume to Bourdieu's now seminal An Invitation to Reflexive Sociology (...) . In this posthumous work, Bourdieu declares that science is in danger of becoming a handmaiden to biotechnology, medicine, genetic engineering, and military research--that it risks falling under the control of industrial corporations that seek to exploit it for monopolies and profit. Science thus endangered can become detrimental to mankind. The line between pure and applied science, therefore, must be subjected to intense theoretical scrutiny. Bourdieu's goals in Science of Science and Reflexivity are to identify the social conditions in which science develops in order to reclaim its objectivity and to rescue it from relativism and the forces that might exploit it. In the grand tradition of scientific reflections on science, Bourdieu provides a sociological analysis of the discipline as something capable of producing transhistorical truths he presents an incisive critique of the main currents in the study of science throughout the past half century and he offers a spirited defense of science against encroaching political and economic forces. A masterful summation of the principles underlying Bourdieu's oeuvre and a memoir of his own scientific journey, Science of Science and Reflexivity is a capstone to one of the most important and prodigious careers in the field of sociology. (shrink)

According to an influential view, one function of mirror neurons (MNs), first discovered in the brain of monkeys, is to underlie third-person mindreading. This view relies on two assumptions: the activity of MNs in an observer’s brain matches (simulates or resonates with) that of MNs in an agent’s brain and this resonance process retrodictively generates a representation of the agent’s intention from a perception of her movement. In this paper, I criticize both assumptions and I argue instead that the activity (...) of MNs in an observer’s brain is enhanced by a prior representation of the agent’s intention and that their task is to predictively compute the best motor command suitable to satisfy the agent’s intention. (shrink)

Pierre Maquet1,2,6, Steven Laureys1,2, Philippe Peigneux1,2,3, Sonia Fuchs1, Christophe Petiau1, Christophe Phillips1,6, Joel Aerts1, Guy Del Fiore1, Christian Degueldre1, Thierry Meulemans3, André Luxen1, Georges Franck1,2, Martial Van Der Linden3, Carlyle Smith4 and Axel Cleeremans5.

A magisterial mappa mundi of the terrain that Pierre Hadot has so productively worked for decades, this ambitious work revises our view of ancient philosophy- ...

We propose a modular ontology of the dynamic features of reality. This amounts, on the one hand, to a purely spatial ontology supporting snapshot views of the world at successive instants of time and, on the other hand, to a purely spatiotemporal ontology of change and process. We argue that dynamic spatial ontology must combine these two distinct types of inventory of the entities and relationships in reality, and we provide characterizations of spatiotemporal reasoning in the light of the interconnections (...) between them. (shrink)

We show that if κ is an infinite successor cardinal, and λ > κ a cardinal of cofinality less than κ satisfying certain conditions, then no ideal on Pκ is weakly λ+-saturated. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Intentionality is the power of minds to be about, to represent, or to stand for, things, properties and states of affairs. The puzzles of intentionality lie at the interface between the philosophy of mind and the philosophy of language. The word itself, which is of medieval Scholastic origin, was rehabilitated by the philosopher Franz Brentano towards the end of the nineteenth century. ‘Intentionality’ is a philosopher's word. It derives from the Latin word intentio, which in turn derives from the verb (...) intendere, which means being directed towards some goal or thing. The entry falls into eleven sections. (shrink)

Are there any advantages to thinking and speaking about ethical business in the language of citizenship? We will address this question in part by looking at the possible relevance of a vast literature on individual citizenship that has been produced by political philosophers over the last fifteen years. Some of the central elements of citizenship do not seem to apply straightforwardly to corporations. E.g., “citizenship” typically implies membership in a state and an identity akin to national identity; but this connotation (...) of citizenship is obviously problematic for multinational corporations. However, the language of citizenship does help to focus our attention on various legal and political virtues (or vices) for corporations—topics that have been largely neglected by discussions under other rubrics, such as CSR or sustainability. We finish with an evaluation of the potential benefits and costs of conceptualizing and talking about ethical business practices in the language of citizenship. (shrink)

Nothing has yet been done, and, here, in the middle of the twentieth century, it is fast becoming too late to draw up a suitable catalogue of the works of human wisdom. We are forced to project for the future the complete realization of our desires. This future will no doubt discover a conscious and effective organization of thought and action—a constant good fortune in the pursuit of legitimate satisfactions through a total mastery of natural forces—in a word, a perfect (...) and reciprocal adaptation between man and that part of the universe in which he lives. All this, or most of it, still remains to be done; but much has already been said in the five thousand years that men have been writing. An intelligent observer arriving from Sirius would doubtless be especially struck by the extraordinary gap separating here on earth what is so well said from what is so badly carried out. Or rather he would wonder how it is that beings as highly gifted as men, judging from the knowledge and wisdom they have accumulated, still make such ineffective and even harmful use of the means at their disposal. The most indulgent hypothesis would be to see in this the result of a temporary misunderstanding owing to the great speed with which human thought evolves. Our observer would resume his journey then, resolved to return after a hundred years or two, sure that he would then find that man had bridged the gap and become as great in what he does as in what he knows. (shrink)

We propose that the isomorphism generally observed between the representations composing our momentary phenomenal experience and the structure of the world is the end-product of a progressive organization that emerges thanks to elementary associative processes that take our conscious representations themselves as the stuff on which they operate, a thesis that we summarize in the concept of Self-Organizing Consciousness (SOC). Key Words: Associative learning; automatism; consciousness; development; implicit learning; incubation; language; mental representation; perception; phenomenal experience.