PurposeTo explore the changes of cerebral blood flow and fractional anisotropy in stroke patients with motor dysfunction after repetitive transcranial magnetic stimulation treatment, and to better understand the role of rTMS on motor rehabilitation of subcortical stroke patients from the perfusion and structural level.Materials and MethodsIn total, 23 first-episode acute ischemic stroke patients and sixteen healthy controls were included. The patients were divided into the rTMS and sham group. The rehabilitation assessments and examination of perfusion and structural MRI were performed (...) before and after rTMS therapy for each patient. Voxel-based analysis was used to detect the difference in CBF and FA among all three groups. The Pearson correlation analysis was conducted to evaluate the relationship between the CBF/FA value and the motor scales.ResultsAfter rTMS, significantly increased CBF was found in the ipsilesional supplementary motor area, postcentral gyrus, precentral gyrus, pons, medulla oblongata, contralesional midbrain, superior cerebellar peduncle, and middle cerebellar peduncle compared to that during the prestimulation and in the sham group, these fasciculi comprise the cortex-pontine-cerebellum-cortex loop. Besides, altered CBF in the ipsilesional precentral gyrus, postcentral gyrus, and pons was positively associated with the improved Fugl-Meyer assessment scores. Significantly decreased FA was found in the contralesional precentral gyrus, increased FA was found in the ipsilesional postcentral gyrus, precentral gyrus, contralesional supplementary motor area, and bilateral cerebellum, these fasciculi comprise the corticospinal tract. The change of FMA score was positively correlated with altered FA value in the ipsilesional postcentral gyrus and negatively correlated with altered FA value in the contralesional precentral gyrus.ConclusionOur results suggested that rTMS could facilitate the motor recovery of stroke patients. High frequency could promote the improvement of functional activity of ipsilesional CPC loop and the recovery of the microstructure of CST. (shrink)

Guidelines for an ideal Islamic society and the responsibilities of Muslim according to Islamic teachings.

Faith and reason--Islam; Human beings--philosophy; Faith--philosophy; Islamic philosophy.

Logical thinking; criticism and interpretation; Arab philosophers.

Maḥmūd, Zakī Najīb, 1905-; philosophers; Egypt; biography; interview.

Anhand von zwei zentralen Schriften Hans Blumenbergs - den Paradigmen zu einer Metaphorologie (1960) und der Arbeit am Mythos (1979) - widmet sich der Band einer Relekture der ausgefeilten gedanklichen wie sprachlichen Verfahrensweisen, die der Philosoph zumeist unkommentiert zum Einsatz bringt. GEfragt wird damit nicht nur nach den spezifischen Darstellungsmitteln der Texte und dem Verhaltnis, das diese zu den verhandelten Themenkomplexen unterhalten, sondern auch, inwiefern deren reichhaltiges Arsenal an Denk- und Ausdrucksweisen gegenwartig Anschlussmoglichkeiten fur kulturanalytische Fragestellungen bereithalt. Die Beitrage stammen (...) von: Thomas Ballhausen, Eckhardt Kohn, Sebastian Lederle, Oliver Muller, Wolfgang Muller-Funk, Mauro Ponzi, Vahidin Preljevic, Matthias Schmidt, Tanja Veverka, Luca Viglialoro und Rudiger Zill. (shrink)

Maudoodi, Syed Abul ʻAla, 1903-1979; philisophy.

Islamic modernism; Islamic philosophy; 20th century.

A comprehensive biography which covers Adorno's life, work and times: from childhood, through to his student years, his years in emigration, his return to post-war Germany, his time in Frankfurt, his role as a public intellectual, and his ...

A speed-accuracy trade-off (SAT) in behavioural decisions is known to occur in a wide range of vertebrate and invertebrate taxa. Accurate decisions often take longer for a given condition, while fast decisions can be inaccurate in some tasks. Speed-accuracy tactics are known to vary consistently among individuals, and show a degree of flexibility during colour discrimination tasks in bees. Such individual flexibility in speed-accuracy tactics is likely to be advantageous for animals exposed to fluctuating environments, such as changes in predation (...) threat. We therefore test whether individual speed-accuracy tactics are fixed or flexible under different levels of predation threat in a model invertebrate, the bumblebee Bombus terrestris. The flexibility of speed-accuracy tactics in a foraging context was tested in the laboratory using a ‘meadow’ of artificial flowers harbouring ‘robotic’ crab spider predators. We found that while the ranking of bees along the speed and accuracy continuums was consistent across two levels of predation threat, there was some flexibility in the tactics used by individual bees – most bees became less accurate at colour discrimination when exposed to predation threat when flower types were rewarding. The relationship between decision speed and accuracy was influenced by predator detectability and the risk associated with making incorrect choices during the colour discrimination task. Predator crypsis resulted in a breakdown in the relationship between speed and accuracy, especially when making an incorrect floral choice incurred a distasteful quinine punishment. No single speed-accuracy tactic was found to be optimal in terms of foraging efficiency under either predation threat situation. However, bees that made faster decisions achieved higher nectar collection rates in predator free situations, while accurate bees achieved higher foraging rates under predation threat. Our findings show that while individual bees remain relatively consistent in terms of whether they place greater emphasis on speed or accuracy under predation threat, they can respond flexibly to the additional time costs of detecting predators. (shrink)

2. Saebyŏngnyŏk chʻodang esŏ on pʻyŏnji.